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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Detection and minimally invasive treatment of early squamous lung cancer</title><author><name sortKey="Daniels, Johannes M A" sort="Daniels, Johannes M A" uniqKey="Daniels J" first="Johannes M. A." last="Daniels">Johannes M. A. Daniels</name></author><author><name sortKey="Sutedja, Thomas G" sort="Sutedja, Thomas G" uniqKey="Sutedja T" first="Thomas G." last="Sutedja">Thomas G. Sutedja</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23858332</idno><idno type="pmc">3707338</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707338</idno><idno type="RBID">PMC:3707338</idno><idno type="doi">10.1177/1758834013482345</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000404</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000404</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Detection and minimally invasive treatment of early squamous lung cancer</title><author><name sortKey="Daniels, Johannes M A" sort="Daniels, Johannes M A" uniqKey="Daniels J" first="Johannes M. A." last="Daniels">Johannes M. A. Daniels</name></author><author><name sortKey="Sutedja, Thomas G" sort="Sutedja, Thomas G" uniqKey="Sutedja T" first="Thomas G." last="Sutedja">Thomas G. Sutedja</name></author></analytic><series><title level="j">Therapeutic Advances in Medical Oncology</title><idno type="ISSN">1758-8340</idno><idno type="eISSN">1758-8359</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Non-small cell lung cancer (NSCLC) is the most common cause of cancer deaths worldwide. The majority of patents presenting with NSCLC have advanced disease, which precludes curative treatment. Early detection and treatment might result in the identification of more patients with early central lung cancer and improve survival. In addition, the study of early lung cancer improves understanding of lung carcinogenesis and might also reveal new treatment targets for advanced lung cancer. Bronchoscopic investigation of the central airways can reveal both early central lung cancer <italic>in situ</italic> (stage 0) and other preinvasive lesions such as dysplasia. In the current review we discuss the detection of early squamous lung cancer, the natural history of preinvasive lesions and whether biomarkers can be used to predict progression to cancer. Finally we will review the staging and management of preinvasive lung cancer lesions and the different therapeutic modalities that are available.</p></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ther Adv Med Oncol</journal-id><journal-id journal-id-type="iso-abbrev">Ther Adv Med Oncol</journal-id><journal-id journal-id-type="publisher-id">TAM</journal-id><journal-id journal-id-type="hwp">sptam</journal-id><journal-title-group><journal-title>Therapeutic Advances in Medical Oncology</journal-title></journal-title-group><issn pub-type="ppub">1758-8340</issn><issn pub-type="epub">1758-8359</issn><publisher><publisher-name>SAGE Publications</publisher-name><publisher-loc>Sage UK: London, England</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23858332</article-id><article-id pub-id-type="pmc">3707338</article-id><article-id pub-id-type="doi">10.1177/1758834013482345</article-id><article-id pub-id-type="publisher-id">10.1177_1758834013482345</article-id><article-categories><subj-group subj-group-type="heading"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Detection and minimally invasive treatment of early squamous lung cancer</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Daniels</surname><given-names>Johannes M.A.</given-names></name><aff id="aff1-1758834013482345">Department of Pulmonary Diseases, Z 4A48, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands</aff></contrib><contrib contrib-type="author"><name><surname>Sutedja</surname><given-names>Thomas G.</given-names></name><aff id="aff2-1758834013482345">Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands</aff></contrib></contrib-group><author-notes><corresp id="corresp1-1758834013482345"><email>j.daniels@vumc.nl</email></corresp></author-notes><pub-date pub-type="epub-ppub"><month>7</month><year>2013</year></pub-date><pmc-comment>Fake ppub date generated by PMC from publisher
pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub"><month>7</month><year>2013</year></pub-date><volume>5</volume><issue>4</issue><fpage>235</fpage><lpage>248</lpage><permissions><copyright-statement>© The Author(s), 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder content-type="sage">SAGE Publications</copyright-holder></permissions><abstract><p>Non-small cell lung cancer (NSCLC) is the most common cause of cancer deaths worldwide. The majority of patents presenting with NSCLC have advanced disease, which precludes curative treatment. Early detection and treatment might result in the identification of more patients with early central lung cancer and improve survival. In addition, the study of early lung cancer improves understanding of lung carcinogenesis and might also reveal new treatment targets for advanced lung cancer. Bronchoscopic investigation of the central airways can reveal both early central lung cancer <italic>in situ</italic> (stage 0) and other preinvasive lesions such as dysplasia. In the current review we discuss the detection of early squamous lung cancer, the natural history of preinvasive lesions and whether biomarkers can be used to predict progression to cancer. Finally we will review the staging and management of preinvasive lung cancer lesions and the different therapeutic modalities that are available.</p></abstract><kwd-group><kwd>biomarkers</kwd><kwd>diagnosis</kwd><kwd>non-small cell lung cancer</kwd><kwd>treatment</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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