Detection and minimally invasive treatment of early squamous lung cancer
Identifieur interne : 000404 ( Pmc/Corpus ); précédent : 000403; suivant : 000405Detection and minimally invasive treatment of early squamous lung cancer
Auteurs : Johannes M. A. Daniels ; Thomas G. SutedjaSource :
- Therapeutic Advances in Medical Oncology [ 1758-8340 ] ; 2013.
Abstract
Non-small cell lung cancer (NSCLC) is the most common cause of cancer deaths worldwide. The majority of patents presenting with NSCLC have advanced disease, which precludes curative treatment. Early detection and treatment might result in the identification of more patients with early central lung cancer and improve survival. In addition, the study of early lung cancer improves understanding of lung carcinogenesis and might also reveal new treatment targets for advanced lung cancer. Bronchoscopic investigation of the central airways can reveal both early central lung cancer
Url:
DOI: 10.1177/1758834013482345
PubMed: 23858332
PubMed Central: 3707338
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PMC:3707338Le document en format XML
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<author><name sortKey="Daniels, Johannes M A" sort="Daniels, Johannes M A" uniqKey="Daniels J" first="Johannes M. A." last="Daniels">Johannes M. A. Daniels</name>
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<series><title level="j">Therapeutic Advances in Medical Oncology</title>
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<front><div type="abstract" xml:lang="en"><p>Non-small cell lung cancer (NSCLC) is the most common cause of cancer deaths worldwide. The majority of patents presenting with NSCLC have advanced disease, which precludes curative treatment. Early detection and treatment might result in the identification of more patients with early central lung cancer and improve survival. In addition, the study of early lung cancer improves understanding of lung carcinogenesis and might also reveal new treatment targets for advanced lung cancer. Bronchoscopic investigation of the central airways can reveal both early central lung cancer <italic>in situ</italic>
(stage 0) and other preinvasive lesions such as dysplasia. In the current review we discuss the detection of early squamous lung cancer, the natural history of preinvasive lesions and whether biomarkers can be used to predict progression to cancer. Finally we will review the staging and management of preinvasive lung cancer lesions and the different therapeutic modalities that are available.</p>
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<pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ther Adv Med Oncol</journal-id>
<journal-id journal-id-type="iso-abbrev">Ther Adv Med Oncol</journal-id>
<journal-id journal-id-type="publisher-id">TAM</journal-id>
<journal-id journal-id-type="hwp">sptam</journal-id>
<journal-title-group><journal-title>Therapeutic Advances in Medical Oncology</journal-title>
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<issn pub-type="ppub">1758-8340</issn>
<issn pub-type="epub">1758-8359</issn>
<publisher><publisher-name>SAGE Publications</publisher-name>
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<article-id pub-id-type="publisher-id">10.1177_1758834013482345</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Reviews</subject>
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<title-group><article-title>Detection and minimally invasive treatment of early squamous lung cancer</article-title>
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<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Daniels</surname>
<given-names>Johannes M.A.</given-names>
</name>
<aff id="aff1-1758834013482345">Department of Pulmonary Diseases, Z 4A48, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Sutedja</surname>
<given-names>Thomas G.</given-names>
</name>
<aff id="aff2-1758834013482345">Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands</aff>
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<author-notes><corresp id="corresp1-1758834013482345"><email>j.daniels@vumc.nl</email>
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<pub-date pub-type="epub-ppub"><month>7</month>
<year>2013</year>
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<pmc-comment>Fake ppub date generated by PMC from publisher
pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub"><month>7</month>
<year>2013</year>
</pub-date>
<volume>5</volume>
<issue>4</issue>
<fpage>235</fpage>
<lpage>248</lpage>
<permissions><copyright-statement>© The Author(s), 2013</copyright-statement>
<copyright-year>2013</copyright-year>
<copyright-holder content-type="sage">SAGE Publications</copyright-holder>
</permissions>
<abstract><p>Non-small cell lung cancer (NSCLC) is the most common cause of cancer deaths worldwide. The majority of patents presenting with NSCLC have advanced disease, which precludes curative treatment. Early detection and treatment might result in the identification of more patients with early central lung cancer and improve survival. In addition, the study of early lung cancer improves understanding of lung carcinogenesis and might also reveal new treatment targets for advanced lung cancer. Bronchoscopic investigation of the central airways can reveal both early central lung cancer <italic>in situ</italic>
(stage 0) and other preinvasive lesions such as dysplasia. In the current review we discuss the detection of early squamous lung cancer, the natural history of preinvasive lesions and whether biomarkers can be used to predict progression to cancer. Finally we will review the staging and management of preinvasive lung cancer lesions and the different therapeutic modalities that are available.</p>
</abstract>
<kwd-group><kwd>biomarkers</kwd>
<kwd>diagnosis</kwd>
<kwd>non-small cell lung cancer</kwd>
<kwd>treatment</kwd>
</kwd-group>
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</front>
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</record>
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