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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Novel Wavelengths for Laser Nerve Stimulation</title>
<author><name sortKey="Mccaughey, Ryan G" sort="Mccaughey, Ryan G" uniqKey="Mccaughey R" first="Ryan G." last="Mccaughey">Ryan G. Mccaughey</name>
</author>
<author><name sortKey="Chlebicki, Cara" sort="Chlebicki, Cara" uniqKey="Chlebicki C" first="Cara" last="Chlebicki">Cara Chlebicki</name>
</author>
<author><name sortKey="Wong, Brian J F" sort="Wong, Brian J F" uniqKey="Wong B" first="Brian J. F." last="Wong">Brian J. F. Wong</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">19802885</idno>
<idno type="pmc">4144435</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144435</idno>
<idno type="RBID">PMC:4144435</idno>
<idno type="doi">10.1002/lsm.20856</idno>
<date when="2010">2010</date>
<idno type="wicri:Area/Pmc/Corpus">000328</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000328</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Novel Wavelengths for Laser Nerve Stimulation</title>
<author><name sortKey="Mccaughey, Ryan G" sort="Mccaughey, Ryan G" uniqKey="Mccaughey R" first="Ryan G." last="Mccaughey">Ryan G. Mccaughey</name>
</author>
<author><name sortKey="Chlebicki, Cara" sort="Chlebicki, Cara" uniqKey="Chlebicki C" first="Cara" last="Chlebicki">Cara Chlebicki</name>
</author>
<author><name sortKey="Wong, Brian J F" sort="Wong, Brian J F" uniqKey="Wong B" first="Brian J. F." last="Wong">Brian J. F. Wong</name>
</author>
</analytic>
<series><title level="j">Lasers in surgery and medicine</title>
<idno type="ISSN">0196-8092</idno>
<idno type="eISSN">1096-9101</idno>
<imprint><date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">Laser light is known to stimulate nerves. This study investigated alternative wavelengths for nerve stimulation.</p>
</sec>
<sec id="S2"><title>Materials and Methods</title>
<p id="P2">The sciatic nerves of rats were irradiated with four different lasers—a Ho:YAG (2100 nm), a Yb:glass fiber laser (1495 nm) and diode lasers (1450 nm and 1540 nm).</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">All lasers evoked a visible leg twitch response, and electromyography confirmed muscle activation. The Yb:glass laser at 1495 nm delivered through a single mode fiber was found to be the most effective stimulus. The stimulation threshold for a 2 millisecond pulse from the Yb:glass laser was determined to be 3.7 ± 2.8 mJ/cm<sup>2</sup>
.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">The Yb:glass laser has the potential for use in neurostimulation, as an alternative to electrical stimulation.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8007168</journal-id>
<journal-id journal-id-type="pubmed-jr-id">5477</journal-id>
<journal-id journal-id-type="nlm-ta">Lasers Surg Med</journal-id>
<journal-id journal-id-type="iso-abbrev">Lasers Surg Med</journal-id>
<journal-title-group><journal-title>Lasers in surgery and medicine</journal-title>
</journal-title-group>
<issn pub-type="ppub">0196-8092</issn>
<issn pub-type="epub">1096-9101</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">19802885</article-id>
<article-id pub-id-type="pmc">4144435</article-id>
<article-id pub-id-type="doi">10.1002/lsm.20856</article-id>
<article-id pub-id-type="manuscript">NIHMS616664</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Novel Wavelengths for Laser Nerve Stimulation</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>McCaughey</surname>
<given-names>Ryan G.</given-names>
</name>
<degrees>PhD</degrees>
<xref rid="FN1" ref-type="author-notes">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chlebicki</surname>
<given-names>Cara</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Wong</surname>
<given-names>Brian J.F.</given-names>
</name>
<degrees>MD, PhD</degrees>
</contrib>
<aff id="A1">Beckman Laser Institute and Medical Clinic, University of California, Irvine, California 92612</aff>
</contrib-group>
<author-notes><corresp id="FN1"><label>*</label>
Correspondence to: Ryan G. McCaughey, PhD, Beckman Laser Institute, 1002 Health Sciences Rd, Irvine, CA 92612. <email>ryanmccaughey@hotmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>30</day>
<month>7</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub"><month>1</month>
<year>2010</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>26</day>
<month>8</month>
<year>2014</year>
</pub-date>
<volume>42</volume>
<issue>1</issue>
<fpage>69</fpage>
<lpage>75</lpage>
<pmc-comment>elocation-id from pubmed: 10.1002/lsm.20856</pmc-comment>
<permissions><copyright-statement>© 2009 Wiley-Liss, Inc.</copyright-statement>
<copyright-year>2009</copyright-year>
</permissions>
<abstract><sec id="S1"><title>Background</title>
<p id="P1">Laser light is known to stimulate nerves. This study investigated alternative wavelengths for nerve stimulation.</p>
</sec>
<sec id="S2"><title>Materials and Methods</title>
<p id="P2">The sciatic nerves of rats were irradiated with four different lasers—a Ho:YAG (2100 nm), a Yb:glass fiber laser (1495 nm) and diode lasers (1450 nm and 1540 nm).</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">All lasers evoked a visible leg twitch response, and electromyography confirmed muscle activation. The Yb:glass laser at 1495 nm delivered through a single mode fiber was found to be the most effective stimulus. The stimulation threshold for a 2 millisecond pulse from the Yb:glass laser was determined to be 3.7 ± 2.8 mJ/cm<sup>2</sup>
.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">The Yb:glass laser has the potential for use in neurostimulation, as an alternative to electrical stimulation.</p>
</sec>
</abstract>
<kwd-group><kwd>nerve stimulation</kwd>
<kwd>laser</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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