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Bipolar plasma vaporization versus standard transurethral resection in secondary bladder neck sclerosis: a prospective, medium-term, randomized comparison

Identifieur interne : 000296 ( Pmc/Corpus ); précédent : 000295; suivant : 000297

Bipolar plasma vaporization versus standard transurethral resection in secondary bladder neck sclerosis: a prospective, medium-term, randomized comparison

Auteurs : Bogdan Geavlete ; Cristian Moldoveanu ; Catalin Iacoboaie ; Petrisor Geavlete

Source :

RBID : PMC:3607491

Abstract

Objectives:

This prospective, randomized, medium-term trial aimed to assess the efficiency, safety and postoperative results of bipolar plasma vaporization (BPV) in comparison with monopolar transurethral resection (TUR) in cases of secondary bladder neck sclerosis (BNS).

Methods:

A total of 70 patients with BNS secondary to transurethral resection of the prostate (TURP; 46 cases), open prostatectomy for benign prostatic hypertrophy (BPH; 18 cases) and radical prostatectomy for prostate cancer (6 cases) were enrolled in the trial. The inclusion criteria consisted of maximum flow rate (Qmax) <10 ml/s and International Prostate Symptom Score (IPSS) >19. All patients were evaluated preoperatively and at 1, 3, 6, 12 and 18 months after surgery by IPSS, quality of life score (QoL), Qmax and postvoiding residual urinary volume (PVR).

Results:

The mean operation time (10.3 versus 14.9 minutes), catheterization period (0.75 versus 2.1 days) and hospital stay (1.1 versus 3.2 days) were significantly reduced in the BPV series. During the immediate postoperative follow up, recatheterization for acute urinary retention only occurred in the TUR series (5.7%). The medium-term retreatment requirements due to BNS recurrence were lower in the BPV study arm (2.8% versus 8.5%). At the 1, 3, 6, 12 and 18 months assessments, statistically similar parameters were found concerning the IPSS and QoL symptom scores, Qmax and PVR values specific for the two therapeutic alternatives.

Conclusions:

BPV constitutes a valuable endoscopic treatment approach for secondary BNS. The method emphasized superior efficacy, a satisfactory safety profile and similar medium-term follow-up features when compared with standard TUR.


Url:
DOI: 10.1177/1756287212470695
PubMed: 23554842
PubMed Central: 3607491

Links to Exploration step

PMC:3607491

Le document en format XML

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standard transurethral resection in secondary bladder neck sclerosis: a prospective, medium-term, randomized comparison</title>
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<name sortKey="Geavlete, Bogdan" sort="Geavlete, Bogdan" uniqKey="Geavlete B" first="Bogdan" last="Geavlete">Bogdan Geavlete</name>
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<name sortKey="Moldoveanu, Cristian" sort="Moldoveanu, Cristian" uniqKey="Moldoveanu C" first="Cristian" last="Moldoveanu">Cristian Moldoveanu</name>
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<name sortKey="Iacoboaie, Catalin" sort="Iacoboaie, Catalin" uniqKey="Iacoboaie C" first="Catalin" last="Iacoboaie">Catalin Iacoboaie</name>
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<name sortKey="Geavlete, Petrisor" sort="Geavlete, Petrisor" uniqKey="Geavlete P" first="Petrisor" last="Geavlete">Petrisor Geavlete</name>
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standard transurethral resection in secondary bladder neck sclerosis: a prospective, medium-term, randomized comparison</title>
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<name sortKey="Geavlete, Bogdan" sort="Geavlete, Bogdan" uniqKey="Geavlete B" first="Bogdan" last="Geavlete">Bogdan Geavlete</name>
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<div type="abstract" xml:lang="en">
<sec id="section1-1756287212470695">
<title>Objectives:</title>
<p>This prospective, randomized, medium-term trial aimed to assess the efficiency, safety and postoperative results of bipolar plasma vaporization (BPV) in comparison with monopolar transurethral resection (TUR) in cases of secondary bladder neck sclerosis (BNS).</p>
</sec>
<sec id="section2-1756287212470695">
<title>Methods:</title>
<p>A total of 70 patients with BNS secondary to transurethral resection of the prostate (TURP; 46 cases), open prostatectomy for benign prostatic hypertrophy (BPH; 18 cases) and radical prostatectomy for prostate cancer (6 cases) were enrolled in the trial. The inclusion criteria consisted of maximum flow rate (
<italic>Q</italic>
<sub>max</sub>
) <10 ml/s and International Prostate Symptom Score (IPSS) >19. All patients were evaluated preoperatively and at 1, 3, 6, 12 and 18 months after surgery by IPSS, quality of life score (QoL),
<italic>Q</italic>
<sub>max</sub>
and postvoiding residual urinary volume (PVR).</p>
</sec>
<sec id="section3-1756287212470695">
<title>Results:</title>
<p>The mean operation time (10.3
<italic>versus</italic>
14.9 minutes), catheterization period (0.75
<italic>versus</italic>
2.1 days) and hospital stay (1.1
<italic>versus</italic>
3.2 days) were significantly reduced in the BPV series. During the immediate postoperative follow up, recatheterization for acute urinary retention only occurred in the TUR series (5.7%). The medium-term retreatment requirements due to BNS recurrence were lower in the BPV study arm (2.8%
<italic>versus</italic>
8.5%). At the 1, 3, 6, 12 and 18 months assessments, statistically similar parameters were found concerning the IPSS and QoL symptom scores,
<italic>Q</italic>
<sub>max</sub>
and PVR values specific for the two therapeutic alternatives.</p>
</sec>
<sec id="section4-1756287212470695">
<title>Conclusions:</title>
<p>BPV constitutes a valuable endoscopic treatment approach for secondary BNS. The method emphasized superior efficacy, a satisfactory safety profile and similar medium-term follow-up features when compared with standard TUR.</p>
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</div>
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<journal-id journal-id-type="nlm-ta">Ther Adv Urol</journal-id>
<journal-id journal-id-type="iso-abbrev">Ther Adv Urol</journal-id>
<journal-id journal-id-type="publisher-id">TAU</journal-id>
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<article-title>Bipolar plasma vaporization
<italic>versus</italic>
standard transurethral resection in secondary bladder neck sclerosis: a prospective, medium-term, randomized comparison</article-title>
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<contrib contrib-type="author">
<name>
<surname>Geavlete</surname>
<given-names>Bogdan</given-names>
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<aff id="aff1-1756287212470695">‘Saint John’ Emergency Clinical Hospital, Department of Urology, Bucharest, Romania</aff>
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<contrib contrib-type="author">
<name>
<surname>Moldoveanu</surname>
<given-names>Cristian</given-names>
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<aff id="aff2-1756287212470695">‘Saint John’ Emergency Clinical Hospital, Department of Urology, Bucharest, Romania</aff>
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<name>
<surname>Iacoboaie</surname>
<given-names>Catalin</given-names>
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<aff id="aff3-1756287212470695">‘Saint John’ Emergency Clinical Hospital, Department of Urology, Bucharest, Romania</aff>
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<contrib contrib-type="author" corresp="yes">
<name>
<surname>Geavlete</surname>
<given-names>Petrisor</given-names>
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<aff id="aff4-1756287212470695">‘Saint John’ Emergency Clinical Hospital, Department of Urology, Vitan Barzesti Street No. 13, Sector 4, Code: 042122, Bucharest, Romania</aff>
</contrib>
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<author-notes>
<corresp id="corresp1-1756287212470695">
<email>geavlete@gmail.com</email>
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<pub-date pub-type="epub-ppub">
<month>4</month>
<year>2013</year>
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<pmc-comment>Fake ppub date generated by PMC from publisher pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub">
<month>4</month>
<year>2013</year>
</pub-date>
<volume>5</volume>
<issue>2</issue>
<fpage>75</fpage>
<lpage>83</lpage>
<permissions>
<copyright-statement>© The Author(s), 2012</copyright-statement>
<copyright-year>2012</copyright-year>
<copyright-holder content-type="sage">SAGE Publications</copyright-holder>
</permissions>
<abstract>
<sec id="section1-1756287212470695">
<title>Objectives:</title>
<p>This prospective, randomized, medium-term trial aimed to assess the efficiency, safety and postoperative results of bipolar plasma vaporization (BPV) in comparison with monopolar transurethral resection (TUR) in cases of secondary bladder neck sclerosis (BNS).</p>
</sec>
<sec id="section2-1756287212470695">
<title>Methods:</title>
<p>A total of 70 patients with BNS secondary to transurethral resection of the prostate (TURP; 46 cases), open prostatectomy for benign prostatic hypertrophy (BPH; 18 cases) and radical prostatectomy for prostate cancer (6 cases) were enrolled in the trial. The inclusion criteria consisted of maximum flow rate (
<italic>Q</italic>
<sub>max</sub>
) <10 ml/s and International Prostate Symptom Score (IPSS) >19. All patients were evaluated preoperatively and at 1, 3, 6, 12 and 18 months after surgery by IPSS, quality of life score (QoL),
<italic>Q</italic>
<sub>max</sub>
and postvoiding residual urinary volume (PVR).</p>
</sec>
<sec id="section3-1756287212470695">
<title>Results:</title>
<p>The mean operation time (10.3
<italic>versus</italic>
14.9 minutes), catheterization period (0.75
<italic>versus</italic>
2.1 days) and hospital stay (1.1
<italic>versus</italic>
3.2 days) were significantly reduced in the BPV series. During the immediate postoperative follow up, recatheterization for acute urinary retention only occurred in the TUR series (5.7%). The medium-term retreatment requirements due to BNS recurrence were lower in the BPV study arm (2.8%
<italic>versus</italic>
8.5%). At the 1, 3, 6, 12 and 18 months assessments, statistically similar parameters were found concerning the IPSS and QoL symptom scores,
<italic>Q</italic>
<sub>max</sub>
and PVR values specific for the two therapeutic alternatives.</p>
</sec>
<sec id="section4-1756287212470695">
<title>Conclusions:</title>
<p>BPV constitutes a valuable endoscopic treatment approach for secondary BNS. The method emphasized superior efficacy, a satisfactory safety profile and similar medium-term follow-up features when compared with standard TUR.</p>
</sec>
</abstract>
<kwd-group>
<kwd>bipolar plasma vaporization</kwd>
<kwd>monopolar transurethral resection</kwd>
<kwd>secondary bladder neck sclerosis.</kwd>
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</front>
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</record>

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