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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Temporal and spatial temperature distributions on glabrous skin irradiated by a 1940 nm continuous-wave laser stimulator</title><author><name sortKey="Yang, Ji Chun" sort="Yang, Ji Chun" uniqKey="Yang J" first="Ji-Chun" last="Yang">Ji-Chun Yang</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Dong, Xiao Xi" sort="Dong, Xiao Xi" uniqKey="Dong X" first="Xiao-Xi" last="Dong">Xiao-Xi Dong</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation><affiliation><nlm:aff id="aff3">Xiao-xi Dong and Ji-chun Yang contributed equally to this work.</nlm:aff></affiliation></author><author><name sortKey="Mu, Zhi Ming" sort="Mu, Zhi Ming" uniqKey="Mu Z" first="Zhi-Ming" last="Mu">Zhi-Ming Mu</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Jin, Wen Dong" sort="Jin, Wen Dong" uniqKey="Jin W" first="Wen-Dong" last="Jin">Wen-Dong Jin</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Huang, He" sort="Huang, He" uniqKey="Huang H" first="He" last="Huang">He Huang</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Lu, Yu" sort="Lu, Yu" uniqKey="Lu Y" first="Yu" last="Lu">Yu Lu</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation><affiliation><nlm:aff id="aff2">Tianjin University of Technology and Education, Electronic Engineering College, No.1310, Dagu South Road, Tianjin, 300222,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Chen, Zhu Ying" sort="Chen, Zhu Ying" uniqKey="Chen Z" first="Zhu-Ying" last="Chen">Zhu-Ying Chen</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Li, Ying Xin" sort="Li, Ying Xin" uniqKey="Li Y" first="Ying-Xin" last="Li">Ying-Xin Li</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25909027</idno><idno type="pmc">4399682</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399682</idno><idno type="RBID">PMC:4399682</idno><idno type="doi">10.1364/BOE.6.001451</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000263</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000263</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Temporal and spatial temperature distributions on glabrous skin irradiated by a 1940 nm continuous-wave laser stimulator</title><author><name sortKey="Yang, Ji Chun" sort="Yang, Ji Chun" uniqKey="Yang J" first="Ji-Chun" last="Yang">Ji-Chun Yang</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Dong, Xiao Xi" sort="Dong, Xiao Xi" uniqKey="Dong X" first="Xiao-Xi" last="Dong">Xiao-Xi Dong</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation><affiliation><nlm:aff id="aff3">Xiao-xi Dong and Ji-chun Yang contributed equally to this work.</nlm:aff></affiliation></author><author><name sortKey="Mu, Zhi Ming" sort="Mu, Zhi Ming" uniqKey="Mu Z" first="Zhi-Ming" last="Mu">Zhi-Ming Mu</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Jin, Wen Dong" sort="Jin, Wen Dong" uniqKey="Jin W" first="Wen-Dong" last="Jin">Wen-Dong Jin</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Huang, He" sort="Huang, He" uniqKey="Huang H" first="He" last="Huang">He Huang</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Lu, Yu" sort="Lu, Yu" uniqKey="Lu Y" first="Yu" last="Lu">Yu Lu</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation><affiliation><nlm:aff id="aff2">Tianjin University of Technology and Education, Electronic Engineering College, No.1310, Dagu South Road, Tianjin, 300222,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Chen, Zhu Ying" sort="Chen, Zhu Ying" uniqKey="Chen Z" first="Zhu-Ying" last="Chen">Zhu-Ying Chen</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author><author><name sortKey="Li, Ying Xin" sort="Li, Ying Xin" uniqKey="Li Y" first="Ying-Xin" last="Li">Ying-Xin Li</name><affiliation><nlm:aff id="aff1">Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></nlm:aff></affiliation></author></analytic><series><title level="j">Biomedical Optics Express</title><idno type="eISSN">2156-7085</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>For predicting pain stimulation effects and avoiding damage in 1940nm laser evoked potentials (LEPs) experiments, a 2-layer finite element model (FEM-2) was constructed. A series of experiments were conducted on <italic>ex-vivo</italic> pig skin pieces to verify temperature distribution predicted by this model. Various laser powers and beam radii were employed. Experimental data of time-dependent temperature responses in different sub-skin depths and space-dependent surface temperature was recorded by thermocouple instrument. By comparing with the experimental data and model results, FEM-2 model was proved to predict temperature distributions accurately. A logarithmic relationship between laser power density and temperature increment was revealed by the results. It is concluded that power density is an effective parameter to estimate pain and damage effect. The obtained results also indicated that the proposed FEM-2 model can be extended to predict pain and damage thresholds of human skin samples and thus contribute to LEPs study.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Biomed Opt Express</journal-id><journal-id journal-id-type="iso-abbrev">Biomed Opt Express</journal-id><journal-id journal-id-type="publisher-id">BOE</journal-id><journal-title-group><journal-title>Biomedical Optics Express</journal-title></journal-title-group><issn pub-type="epub">2156-7085</issn><publisher><publisher-name>Optical Society of America</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25909027</article-id><article-id pub-id-type="pmc">4399682</article-id><article-id pub-id-type="publisher-id">1451</article-id><article-id pub-id-type="doi">10.1364/BOE.6.001451</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Temporal and spatial temperature distributions on glabrous skin irradiated by a 1940 nm continuous-wave laser stimulator</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Yang</surname><given-names>Ji-chun</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><name><surname>Dong</surname><given-names>Xiao-xi</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Mu</surname><given-names>Zhi-ming</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Jin</surname><given-names>Wen-dong</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>He</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Lu</surname><given-names>Yu</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Zhu-ying</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Ying-xin</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><aff id="aff1"><label>1</label>Chinese Academy of Medical Science &Peking Union Medical College, Institute of Biomedical Engineering, Laboratory of Laser Medicine, No.236, Baidi Road, Tianjin, 300192,<country country="CN">China</country></aff><aff id="aff2"><label>2</label>Tianjin University of Technology and Education, Electronic Engineering College, No.1310, Dagu South Road, Tianjin, 300222,<country country="CN">China</country></aff><aff id="aff3"><label>3</label>Xiao-xi Dong and Ji-chun Yang contributed equally to this work.</aff></contrib-group><author-notes><corresp id="cor1"><label>*</label><email xlink:href="yingxinli2005@126.com">yingxinli2005@126.com</email></corresp></author-notes><pub-date pub-type="epub"><day>24</day><month>3</month><year>2015</year></pub-date><pub-date pub-type="collection"><day>01</day><month>4</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>24</day><month>3</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>6</volume><issue>4</issue><fpage>1451</fpage><lpage>1463</lpage><history><date date-type="received"><day>15</day><month>12</month><year>2014</year></date><date date-type="rev-recd"><day>14</day><month>2</month><year>2015</year></date><date date-type="accepted"><day>23</day><month>2</month><year>2015</year></date></history><permissions><copyright-statement>© 2015 Optical Society of America</copyright-statement><copyright-year>2015</copyright-year><copyright-holder>Optical Society of America</copyright-holder></permissions><abstract><p>For predicting pain stimulation effects and avoiding damage in 1940nm laser evoked potentials (LEPs) experiments, a 2-layer finite element model (FEM-2) was constructed. A series of experiments were conducted on <italic>ex-vivo</italic> pig skin pieces to verify temperature distribution predicted by this model. Various laser powers and beam radii were employed. Experimental data of time-dependent temperature responses in different sub-skin depths and space-dependent surface temperature was recorded by thermocouple instrument. By comparing with the experimental data and model results, FEM-2 model was proved to predict temperature distributions accurately. A logarithmic relationship between laser power density and temperature increment was revealed by the results. It is concluded that power density is an effective parameter to estimate pain and damage effect. The obtained results also indicated that the proposed FEM-2 model can be extended to predict pain and damage thresholds of human skin samples and thus contribute to LEPs study.</p></abstract><kwd-group kwd-group-type="OCIS"><title>OCIS codes: </title><kwd>(140.0140) Lasers and laser optics</kwd><kwd>(140.3330) Laser damage</kwd><kwd>(140.6810) Thermal effects</kwd><kwd>(140.3580) Lasers, solid-state</kwd><kwd>(170.0170) Medical optics and biotechnology</kwd><kwd>(170.3660) Light propagation in tissues</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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