Serveur d'exploration sur le thulium

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A prospective, randomized comparison of a 1940 nm and a 2013 nm thulium: yttrium–aluminum–garnet laser device for Thulium VapoEnucleation of the prostate (ThuVEP): First results

Identifieur interne : 000084 ( Pmc/Checkpoint ); précédent : 000083; suivant : 000085

A prospective, randomized comparison of a 1940 nm and a 2013 nm thulium: yttrium–aluminum–garnet laser device for Thulium VapoEnucleation of the prostate (ThuVEP): First results

Auteurs : Christian Tiburtius [Allemagne] ; Andreas J. Gross [Allemagne] ; Christopher Netsch [Allemagne]

Source :

RBID : PMC:4300572

Abstract

Introduction:

We report the early postoperative results of the first prospective, randomized comparison of two commercially available thulium lasers with different wavelengths for the treatment of benign prostatic obstruction (BPO).

Materials and Methods:

From January to June 2013, 80 consecutive patients were randomized for Thulium VapoEnucleation of the prostate (ThuVEP) with a 2013 nm (RevoLix®) (n = 39) or a 1940 nm (Vela®XL) (n = 41) thulium laser. Preoperative status, surgical details and the immediate outcome were recorded for each patient. The perioperative complications were assessed and classified according to the modified Clavien classification system.

Results:

Median operation time, resected tissue, percentage of resected tissue, catheter time, overall operation efficiency and Hb loss differed nonsignificantly between both devices (P > 0.05). At discharge, the median maximum urinary flow rate and postvoiding residual (PVR) urine improved significantly in both groups (P < 0.001). The PVR was lower in the 1940 nm ThuVEP group (P ≤ 0.034). Perioperative complications occurred in 18 (22.5%) patients (Clavien 1: 12.5%; Clavien 2: 5%, Clavien 3b: 2.5%, Clavien 4a: 2.5%), with no differences between the groups (P = 0.5).

Conclusions:

The 1940 nm and the 2013 nm thulium lasers are both safe and effective for the treatment of BPO with ThuVEP. Both lasers give equivalent and satisfactory immediate micturition improvement with low perioperative morbidity.


Url:
DOI: 10.4103/0970-1591.148308
PubMed: 25624576
PubMed Central: 4300572


Affiliations:


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PMC:4300572

Le document en format XML

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<title>Introduction:</title>
<p>We report the early postoperative results of the first prospective, randomized comparison of two commercially available thulium lasers with different wavelengths for the treatment of benign prostatic obstruction (BPO).</p>
</sec>
<sec id="st2">
<title>Materials and Methods:</title>
<p>From January to June 2013, 80 consecutive patients were randomized for Thulium VapoEnucleation of the prostate (ThuVEP) with a 2013 nm (RevoLix
<sup>®</sup>
) (
<italic>n</italic>
= 39) or a 1940 nm (Vela
<sup>®</sup>
XL) (
<italic>n</italic>
= 41) thulium laser. Preoperative status, surgical details and the immediate outcome were recorded for each patient. The perioperative complications were assessed and classified according to the modified Clavien classification system.</p>
</sec>
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<title>Results:</title>
<p>Median operation time, resected tissue, percentage of resected tissue, catheter time, overall operation efficiency and Hb loss differed nonsignificantly between both devices (
<italic>P</italic>
> 0.05). At discharge, the median maximum urinary flow rate and postvoiding residual (PVR) urine improved significantly in both groups (
<italic>P</italic>
< 0.001). The PVR was lower in the 1940 nm ThuVEP group (
<italic>P</italic>
≤ 0.034). Perioperative complications occurred in 18 (22.5%) patients (Clavien 1: 12.5%; Clavien 2: 5%, Clavien 3b: 2.5%, Clavien 4a: 2.5%), with no differences between the groups (
<italic>P</italic>
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<title>Conclusions:</title>
<p>The 1940 nm and the 2013 nm thulium lasers are both safe and effective for the treatment of BPO with ThuVEP. Both lasers give equivalent and satisfactory immediate micturition improvement with low perioperative morbidity.</p>
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<name sortKey="Wyler, Sf" uniqKey="Wyler S">SF Wyler</name>
</author>
<author>
<name sortKey="Abe, C" uniqKey="Abe C">C Abe</name>
</author>
<author>
<name sortKey="Rieken, M" uniqKey="Rieken M">M Rieken</name>
</author>
<author>
<name sortKey="Reich, O" uniqKey="Reich O">O Reich</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Gilling, Pj" uniqKey="Gilling P">PJ Gilling</name>
</author>
<author>
<name sortKey="Aho, Tf" uniqKey="Aho T">TF Aho</name>
</author>
<author>
<name sortKey="Frampton, Cm" uniqKey="Frampton C">CM Frampton</name>
</author>
<author>
<name sortKey="King, Cj" uniqKey="King C">CJ King</name>
</author>
<author>
<name sortKey="Fraundorfer, Mr" uniqKey="Fraundorfer M">MR Fraundorfer</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Shah, Hn" uniqKey="Shah H">HN Shah</name>
</author>
<author>
<name sortKey="Mahajan, Ap" uniqKey="Mahajan A">AP Mahajan</name>
</author>
<author>
<name sortKey="Sodha, Hs" uniqKey="Sodha H">HS Sodha</name>
</author>
<author>
<name sortKey="Hegde, S" uniqKey="Hegde S">S Hegde</name>
</author>
<author>
<name sortKey="Mohile, Pd" uniqKey="Mohile P">PD Mohile</name>
</author>
<author>
<name sortKey="Bansal, Mb" uniqKey="Bansal M">MB Bansal</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Indian J Urol</journal-id>
<journal-id journal-id-type="iso-abbrev">Indian J Urol</journal-id>
<journal-id journal-id-type="publisher-id">IJU</journal-id>
<journal-title-group>
<journal-title>Indian Journal of Urology : IJU : Journal of the Urological Society of India</journal-title>
</journal-title-group>
<issn pub-type="ppub">0970-1591</issn>
<issn pub-type="epub">1998-3824</issn>
<publisher>
<publisher-name>Medknow Publications & Media Pvt Ltd</publisher-name>
<publisher-loc>India</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">25624576</article-id>
<article-id pub-id-type="pmc">4300572</article-id>
<article-id pub-id-type="publisher-id">IJU-31-47</article-id>
<article-id pub-id-type="doi">10.4103/0970-1591.148308</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>A prospective, randomized comparison of a 1940 nm and a 2013 nm thulium: yttrium–aluminum–garnet laser device for Thulium VapoEnucleation of the prostate (ThuVEP): First results</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Tiburtius</surname>
<given-names>Christian</given-names>
</name>
<xref ref-type="aff" rid="aff1"></xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gross</surname>
<given-names>Andreas J.</given-names>
</name>
<xref ref-type="aff" rid="aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Netsch</surname>
<given-names>Christopher</given-names>
</name>
<xref ref-type="aff" rid="aff1"></xref>
</contrib>
</contrib-group>
<aff id="aff1">Department of Urology, Asklepios Hospital Barmbek, Rübenkamp 220, 22291 Hamburg, Germany</aff>
<author-notes>
<corresp id="cor1">
<bold>For correspondence:</bold>
Dr. Christian Tiburtius, Department of Urology, Asklepios Hospital Barmbek, Rübenkamp 220, 22291 Hamburg, Germany. E-mail:
<email xlink:href="c.tiburtius@asklepios.com">c.tiburtius@asklepios.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<season>Jan-Mar</season>
<year>2015</year>
</pub-date>
<volume>31</volume>
<issue>1</issue>
<fpage>47</fpage>
<lpage>51</lpage>
<permissions>
<copyright-statement>Copyright: © Indian Journal of Urology</copyright-statement>
<copyright-year>2015</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract>
<sec id="st1">
<title>Introduction:</title>
<p>We report the early postoperative results of the first prospective, randomized comparison of two commercially available thulium lasers with different wavelengths for the treatment of benign prostatic obstruction (BPO).</p>
</sec>
<sec id="st2">
<title>Materials and Methods:</title>
<p>From January to June 2013, 80 consecutive patients were randomized for Thulium VapoEnucleation of the prostate (ThuVEP) with a 2013 nm (RevoLix
<sup>®</sup>
) (
<italic>n</italic>
= 39) or a 1940 nm (Vela
<sup>®</sup>
XL) (
<italic>n</italic>
= 41) thulium laser. Preoperative status, surgical details and the immediate outcome were recorded for each patient. The perioperative complications were assessed and classified according to the modified Clavien classification system.</p>
</sec>
<sec id="st3">
<title>Results:</title>
<p>Median operation time, resected tissue, percentage of resected tissue, catheter time, overall operation efficiency and Hb loss differed nonsignificantly between both devices (
<italic>P</italic>
> 0.05). At discharge, the median maximum urinary flow rate and postvoiding residual (PVR) urine improved significantly in both groups (
<italic>P</italic>
< 0.001). The PVR was lower in the 1940 nm ThuVEP group (
<italic>P</italic>
≤ 0.034). Perioperative complications occurred in 18 (22.5%) patients (Clavien 1: 12.5%; Clavien 2: 5%, Clavien 3b: 2.5%, Clavien 4a: 2.5%), with no differences between the groups (
<italic>P</italic>
= 0.5).</p>
</sec>
<sec id="st4">
<title>Conclusions:</title>
<p>The 1940 nm and the 2013 nm thulium lasers are both safe and effective for the treatment of BPO with ThuVEP. Both lasers give equivalent and satisfactory immediate micturition improvement with low perioperative morbidity.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Benign prostatic obstruction</kwd>
<kwd>VapoEnucleation</kwd>
<kwd>ThuVEP</kwd>
<kwd>Tm: YAG</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>Allemagne</li>
</country>
<region>
<li>Hambourg</li>
</region>
<settlement>
<li>Hambourg</li>
</settlement>
</list>
<tree>
<country name="Allemagne">
<region name="Hambourg">
<name sortKey="Tiburtius, Christian" sort="Tiburtius, Christian" uniqKey="Tiburtius C" first="Christian" last="Tiburtius">Christian Tiburtius</name>
</region>
<name sortKey="Gross, Andreas J" sort="Gross, Andreas J" uniqKey="Gross A" first="Andreas J." last="Gross">Andreas J. Gross</name>
<name sortKey="Netsch, Christopher" sort="Netsch, Christopher" uniqKey="Netsch C" first="Christopher" last="Netsch">Christopher Netsch</name>
</country>
</tree>
</affiliations>
</record>

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