Serveur d'exploration sur le thulium

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Thulium:YAG Vapoenucleation in Large Volume Prostates

Identifieur interne : 000192 ( Pascal/Curation ); précédent : 000191; suivant : 000193

Thulium:YAG Vapoenucleation in Large Volume Prostates

Auteurs : Thorsten Bach [Allemagne] ; Christopher Netsch [Allemagne] ; Laura Pohlmann [Allemagne] ; Thomas R. W. Herrmann [Allemagne] ; Andreas J. Gross [Allemagne]

Source :

RBID : Pascal:12-0005789

Descripteurs français

English descriptors

Abstract

Purpose: Tm:YAG vapoenucleation was introduced as a minimally invasive treatment in patients with benign prostatic obstruction. The efficiency and safety of Tm:YAG vapoenucleation must still be confirmed in large volume prostates to prove the size independence of this promising treatment option. We evaluated the safety and efficiency of Tm:YAG vapoenucleation in patients with a prostate volume of 80 cc or greater and benign prostatic obstruction during a 12-month followup. Materials and Methods: Included in this trial were 90 consecutive patients undergoing 90 W Tm:YAG vapoenucleation. Vapoenucleation was done using the 2 μm continuous wave Tm:YAG laser combined with a mechanical tissue morcellator. We analyzed patient demographic, perioperative and 12-month followup data. Complications were assessed. Results: Mean preoperative prostate volume was 108.6 cc (range 80 to 200), mean International Prostate Symptom Score was 23.5 (range 8 to 35) and mean quality of life score was 4.3 (range 1 to 6). There was an 86% reduction (range 67% to 99%) in prostate volume on transrectal ultrasound by 12 months and an 88% decrease (range 58% to 100%) in prostate specific antigen. International Index of Erectile Function score remained stable. Peak urinary flow rate, International Prostate Symptom Score and quality of life improved significantly (p <0.001), as did post-void residual urine. The overall complication rate was manageable. Two patients required blood transfusion and 10 experienced early postoperative stress incontinence. During followup 7% of patients had symptomatic urinary tract infection and 2 had persistent grade I stress urinary incontinence. The reoperation rate due to urethral stricture was 1.8% during the 12-month followup. Conclusions: Tm:YAG vapoenucleation is a safe, effective and size independent treatment option for benign prostatic obstruction. As shown by reductions in transrectal ultrasound prostate volume and prostate specific antigen, complete removal of the adenoma can be achieved by this procedure.
pA  
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A02 01      @0 JOURAA
A03   1    @0 J. urol.
A05       @2 186
A06       @2 6
A08 01  1  ENG  @1 Thulium:YAG Vapoenucleation in Large Volume Prostates
A11 01  1    @1 BACH (Thorsten)
A11 02  1    @1 NETSCH (Christopher)
A11 03  1    @1 POHLMANN (Laura)
A11 04  1    @1 HERRMANN (Thomas R. W.)
A11 05  1    @1 GROSS (Andreas J.)
A14 01      @1 Departments of Urology, Asklepios Hospital Barmbek @2 Hamburg @3 DEU @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 5 aut.
A14 02      @1 MHH Medical School of Hannover @2 Hannover @3 DEU @Z 4 aut.
A20       @1 2323-2327
A21       @1 2011
A23 01      @0 ENG
A43 01      @1 INIST @2 2081 @5 354000505638820290
A44       @0 0000 @1 © 2012 INIST-CNRS. All rights reserved.
A45       @0 28 ref.
A47 01  1    @0 12-0005789
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A61       @0 A
A64 01  1    @0 The Journal of urology
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C01 01    ENG  @0 Purpose: Tm:YAG vapoenucleation was introduced as a minimally invasive treatment in patients with benign prostatic obstruction. The efficiency and safety of Tm:YAG vapoenucleation must still be confirmed in large volume prostates to prove the size independence of this promising treatment option. We evaluated the safety and efficiency of Tm:YAG vapoenucleation in patients with a prostate volume of 80 cc or greater and benign prostatic obstruction during a 12-month followup. Materials and Methods: Included in this trial were 90 consecutive patients undergoing 90 W Tm:YAG vapoenucleation. Vapoenucleation was done using the 2 μm continuous wave Tm:YAG laser combined with a mechanical tissue morcellator. We analyzed patient demographic, perioperative and 12-month followup data. Complications were assessed. Results: Mean preoperative prostate volume was 108.6 cc (range 80 to 200), mean International Prostate Symptom Score was 23.5 (range 8 to 35) and mean quality of life score was 4.3 (range 1 to 6). There was an 86% reduction (range 67% to 99%) in prostate volume on transrectal ultrasound by 12 months and an 88% decrease (range 58% to 100%) in prostate specific antigen. International Index of Erectile Function score remained stable. Peak urinary flow rate, International Prostate Symptom Score and quality of life improved significantly (p <0.001), as did post-void residual urine. The overall complication rate was manageable. Two patients required blood transfusion and 10 experienced early postoperative stress incontinence. During followup 7% of patients had symptomatic urinary tract infection and 2 had persistent grade I stress urinary incontinence. The reoperation rate due to urethral stricture was 1.8% during the 12-month followup. Conclusions: Tm:YAG vapoenucleation is a safe, effective and size independent treatment option for benign prostatic obstruction. As shown by reductions in transrectal ultrasound prostate volume and prostate specific antigen, complete removal of the adenoma can be achieved by this procedure.
C02 01  X    @0 002B14D02
C02 02  X    @0 002B20B02
C03 01  X  FRE  @0 Adénome de la prostate @2 NM @5 01
C03 01  X  ENG  @0 Benign prostatic hyperplasia @2 NM @5 01
C03 01  X  SPA  @0 Hiperplasia prostática benigna @2 NM @5 01
C03 02  X  FRE  @0 Thulium @2 NC @5 02
C03 02  X  ENG  @0 Thulium @2 NC @5 02
C03 02  X  SPA  @0 Tulio @2 NC @5 02
C03 03  X  FRE  @0 Volume @5 03
C03 03  X  ENG  @0 Volume @5 03
C03 03  X  SPA  @0 Volumen @5 03
C03 04  X  FRE  @0 Prostate @5 05
C03 04  X  ENG  @0 Prostate @5 05
C03 04  X  SPA  @0 Prostata @5 05
C03 05  X  FRE  @0 Laser @5 06
C03 05  X  ENG  @0 Laser @5 06
C03 05  X  SPA  @0 Láser @5 06
C03 06  X  FRE  @0 Traitement @5 08
C03 06  X  ENG  @0 Treatment @5 08
C03 06  X  SPA  @0 Tratamiento @5 08
C03 07  X  FRE  @0 Volatilisation @5 09
C03 07  X  ENG  @0 Volatilization @5 09
C03 07  X  SPA  @0 Volatilización @5 09
C03 08  X  FRE  @0 Néphrologie @5 11
C03 08  X  ENG  @0 Nephrology @5 11
C03 08  X  SPA  @0 Nefrología @5 11
C03 09  X  FRE  @0 Urologie @5 12
C03 09  X  ENG  @0 Urology @5 12
C03 09  X  SPA  @0 Urología @5 12
C07 01  X  FRE  @0 Appareil urogénital @5 37
C07 01  X  ENG  @0 Urogenital system @5 37
C07 01  X  SPA  @0 Aparato urogenital @5 37
C07 02  X  FRE  @0 Pathologie de l'appareil génital mâle @5 38
C07 02  X  ENG  @0 Male genital diseases @5 38
C07 02  X  SPA  @0 Aparato genital macho patología @5 38
C07 03  X  FRE  @0 Pathologie de l'appareil urinaire @5 39
C07 03  X  ENG  @0 Urinary system disease @5 39
C07 03  X  SPA  @0 Aparato urinario patología @5 39
C07 04  X  FRE  @0 Tumeur bénigne @5 40
C07 04  X  ENG  @0 Benign neoplasm @5 40
C07 04  X  SPA  @0 Tumor benigno @5 40
C07 05  X  FRE  @0 Pathologie de la prostate @5 41
C07 05  X  ENG  @0 Prostate disease @5 41
C07 05  X  SPA  @0 Prostata patología @5 41
N21       @1 002
N44 01      @1 OTO
N82       @1 OTO

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Pascal:12-0005789

Le document en format XML

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<div type="abstract" xml:lang="en">Purpose: Tm:YAG vapoenucleation was introduced as a minimally invasive treatment in patients with benign prostatic obstruction. The efficiency and safety of Tm:YAG vapoenucleation must still be confirmed in large volume prostates to prove the size independence of this promising treatment option. We evaluated the safety and efficiency of Tm:YAG vapoenucleation in patients with a prostate volume of 80 cc or greater and benign prostatic obstruction during a 12-month followup. Materials and Methods: Included in this trial were 90 consecutive patients undergoing 90 W Tm:YAG vapoenucleation. Vapoenucleation was done using the 2 μm continuous wave Tm:YAG laser combined with a mechanical tissue morcellator. We analyzed patient demographic, perioperative and 12-month followup data. Complications were assessed. Results: Mean preoperative prostate volume was 108.6 cc (range 80 to 200), mean International Prostate Symptom Score was 23.5 (range 8 to 35) and mean quality of life score was 4.3 (range 1 to 6). There was an 86% reduction (range 67% to 99%) in prostate volume on transrectal ultrasound by 12 months and an 88% decrease (range 58% to 100%) in prostate specific antigen. International Index of Erectile Function score remained stable. Peak urinary flow rate, International Prostate Symptom Score and quality of life improved significantly (p <0.001), as did post-void residual urine. The overall complication rate was manageable. Two patients required blood transfusion and 10 experienced early postoperative stress incontinence. During followup 7% of patients had symptomatic urinary tract infection and 2 had persistent grade I stress urinary incontinence. The reoperation rate due to urethral stricture was 1.8% during the 12-month followup. Conclusions: Tm:YAG vapoenucleation is a safe, effective and size independent treatment option for benign prostatic obstruction. As shown by reductions in transrectal ultrasound prostate volume and prostate specific antigen, complete removal of the adenoma can be achieved by this procedure.</div>
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<s0>Purpose: Tm:YAG vapoenucleation was introduced as a minimally invasive treatment in patients with benign prostatic obstruction. The efficiency and safety of Tm:YAG vapoenucleation must still be confirmed in large volume prostates to prove the size independence of this promising treatment option. We evaluated the safety and efficiency of Tm:YAG vapoenucleation in patients with a prostate volume of 80 cc or greater and benign prostatic obstruction during a 12-month followup. Materials and Methods: Included in this trial were 90 consecutive patients undergoing 90 W Tm:YAG vapoenucleation. Vapoenucleation was done using the 2 μm continuous wave Tm:YAG laser combined with a mechanical tissue morcellator. We analyzed patient demographic, perioperative and 12-month followup data. Complications were assessed. Results: Mean preoperative prostate volume was 108.6 cc (range 80 to 200), mean International Prostate Symptom Score was 23.5 (range 8 to 35) and mean quality of life score was 4.3 (range 1 to 6). There was an 86% reduction (range 67% to 99%) in prostate volume on transrectal ultrasound by 12 months and an 88% decrease (range 58% to 100%) in prostate specific antigen. International Index of Erectile Function score remained stable. Peak urinary flow rate, International Prostate Symptom Score and quality of life improved significantly (p <0.001), as did post-void residual urine. The overall complication rate was manageable. Two patients required blood transfusion and 10 experienced early postoperative stress incontinence. During followup 7% of patients had symptomatic urinary tract infection and 2 had persistent grade I stress urinary incontinence. The reoperation rate due to urethral stricture was 1.8% during the 12-month followup. Conclusions: Tm:YAG vapoenucleation is a safe, effective and size independent treatment option for benign prostatic obstruction. As shown by reductions in transrectal ultrasound prostate volume and prostate specific antigen, complete removal of the adenoma can be achieved by this procedure.</s0>
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<s0>Laser</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Láser</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Volatilisation</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Volatilization</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Volatilización</s0>
<s5>09</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Néphrologie</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Nephrology</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Nefrología</s0>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Urologie</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Urology</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Urología</s0>
<s5>12</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Appareil urogénital</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Urogenital system</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Aparato urogenital</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Pathologie de l'appareil génital mâle</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Male genital diseases</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Aparato genital macho patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Pathologie de l'appareil urinaire</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Urinary system disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Aparato urinario patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Tumeur bénigne</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Benign neoplasm</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Tumor benigno</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Pathologie de la prostate</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Prostate disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Prostata patología</s0>
<s5>41</s5>
</fC07>
<fN21>
<s1>002</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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