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Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy

Identifieur interne : 001196 ( Pascal/Corpus ); précédent : 001195; suivant : 001197

Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy

Auteurs : Ralf Brinkmann ; Ansgar Knipper ; Gerit Droge ; Frank Schroer ; Bernd Gromoll ; Reginald Birngruber

Source :

RBID : Pascal:98-0220474

Descripteurs français

English descriptors

Abstract

Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed for different laser and application parameters. The ablation dynamics in water and tissue was investigated by fast flash photography. Uniform cuts could be achieved with 200- and 318-μm fibers using a free-running holmium laser with a pulse repetition rate of 10 Hz and an average power of up to 4 W. The depth of the cuts could be increased by using a thulium laser with the same laser parameters. By reducing the pulse duration by one order of magnitude, the quality of the incisions was made more irregular, the zone of thermomechanical damage increased, and the cuts became deeper owing to the growing influence of cavitation on shorter laser pulse durations. In a first clinical trial, 20 patients underwent holmium laser therapy to reopen ureteral strictures. Neither bleeding nor other adverse effects due to the laser treatment occurred, showing IR laser ureterotomy to be a suitable and promising minimally invasive technique. © 1998 Society of Photo-Optical Instrumentation Engineers.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A02 01      @0 JBOPFO
A03   1    @0 J. biomed. opt.
A05       @2 3
A06       @2 1
A08 01  1  ENG  @1 Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy
A11 01  1    @1 BRINKMANN (Ralf)
A11 02  1    @1 KNIPPER (Ansgar)
A11 03  1    @1 DROGE (Gerit)
A11 04  1    @1 SCHROER (Frank)
A11 05  1    @1 GROMOLL (Bernd)
A11 06  1    @1 BIRNGRUBER (Reginald)
A14 01      @1 Medical Laser Center Lubeck GmbH, Peter-Monnik-Weg 4, D-23562 Lubeck, Germany @Z 1 aut.
A14 02      @1 Medical University Lubeck, Clinic of Urology, D-23562 Lubeck, Germany @Z 1 aut.
A14 03      @1 Medical University Lubeck, Institute of Pathology, D-23562 Lubeck, Germany @Z 1 aut.
A20       @1 85-95
A21       @1 1998-01
A23 01      @0 ENG
A43 01      @1 AIP
A44       @0 8100 @1 © 1998 American Institute of Physics. All rights reserved.
A47 01  1    @0 98-0220474
A60       @1 P
A61       @0 A
A64   1    @0 Journal of biomedical optics
A66 01      @0 USA
C01 01    ENG  @0 Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed for different laser and application parameters. The ablation dynamics in water and tissue was investigated by fast flash photography. Uniform cuts could be achieved with 200- and 318-μm fibers using a free-running holmium laser with a pulse repetition rate of 10 Hz and an average power of up to 4 W. The depth of the cuts could be increased by using a thulium laser with the same laser parameters. By reducing the pulse duration by one order of magnitude, the quality of the incisions was made more irregular, the zone of thermomechanical damage increased, and the cuts became deeper owing to the growing influence of cavitation on shorter laser pulse durations. In a first clinical trial, 20 patients underwent holmium laser therapy to reopen ureteral strictures. Neither bleeding nor other adverse effects due to the laser treatment occurred, showing IR laser ureterotomy to be a suitable and promising minimally invasive technique. © 1998 Society of Photo-Optical Instrumentation Engineers.
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C03 03  3  ENG  @0 Experimental study
C03 04  3  FRE  @0 Application médicale laser
C03 04  3  ENG  @0 Laser applications in medicine
C03 05  3  FRE  @0 Chirurgie
C03 05  3  ENG  @0 Surgery
C03 06  3  FRE  @0 Fibre optique
C03 06  3  ENG  @0 Optical fibers
C03 07  3  FRE  @0 Découpage
C03 07  3  ENG  @0 Cutting
N21       @1 145
N47 01  1    @0 9802M000229

Format Inist (serveur)

NO : PASCAL 98-0220474 AIP
ET : Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy
AU : BRINKMANN (Ralf); KNIPPER (Ansgar); DROGE (Gerit); SCHROER (Frank); GROMOLL (Bernd); BIRNGRUBER (Reginald)
AF : Medical Laser Center Lubeck GmbH, Peter-Monnik-Weg 4, D-23562 Lubeck, Germany (1 aut.); Medical University Lubeck, Clinic of Urology, D-23562 Lubeck, Germany (1 aut.); Medical University Lubeck, Institute of Pathology, D-23562 Lubeck, Germany (1 aut.)
DT : Publication en série; Niveau analytique
SO : Journal of biomedical optics; ISSN 1083-3668; Coden JBOPFO; Etats-Unis; Da. 1998-01; Vol. 3; No. 1; Pp. 85-95
LA : Anglais
EA : Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed for different laser and application parameters. The ablation dynamics in water and tissue was investigated by fast flash photography. Uniform cuts could be achieved with 200- and 318-μm fibers using a free-running holmium laser with a pulse repetition rate of 10 Hz and an average power of up to 4 W. The depth of the cuts could be increased by using a thulium laser with the same laser parameters. By reducing the pulse duration by one order of magnitude, the quality of the incisions was made more irregular, the zone of thermomechanical damage increased, and the cuts became deeper owing to the growing influence of cavitation on shorter laser pulse durations. In a first clinical trial, 20 patients underwent holmium laser therapy to reopen ureteral strictures. Neither bleeding nor other adverse effects due to the laser treatment occurred, showing IR laser ureterotomy to be a suitable and promising minimally invasive technique. © 1998 Society of Photo-Optical Instrumentation Engineers.
CC : 002A01C; 001D03G02C1
FD : 4262B; 4281; Etude expérimentale; Application médicale laser; Chirurgie; Fibre optique; Découpage
ED : Experimental study; Laser applications in medicine; Surgery; Optical fibers; Cutting
LO : AIP
ID : 98-0220474

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Pascal:98-0220474

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