Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy
Identifieur interne : 001196 ( Pascal/Corpus ); précédent : 001195; suivant : 001197Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy
Auteurs : Ralf Brinkmann ; Ansgar Knipper ; Gerit Droge ; Frank Schroer ; Bernd Gromoll ; Reginald BirngruberSource :
- Journal of biomedical optics [ 1083-3668 ] ; 1998-01.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed for different laser and application parameters. The ablation dynamics in water and tissue was investigated by fast flash photography. Uniform cuts could be achieved with 200- and 318-μm fibers using a free-running holmium laser with a pulse repetition rate of 10 Hz and an average power of up to 4 W. The depth of the cuts could be increased by using a thulium laser with the same laser parameters. By reducing the pulse duration by one order of magnitude, the quality of the incisions was made more irregular, the zone of thermomechanical damage increased, and the cuts became deeper owing to the growing influence of cavitation on shorter laser pulse durations. In a first clinical trial, 20 patients underwent holmium laser therapy to reopen ureteral strictures. Neither bleeding nor other adverse effects due to the laser treatment occurred, showing IR laser ureterotomy to be a suitable and promising minimally invasive technique. © 1998 Society of Photo-Optical Instrumentation Engineers.
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Format Inist (serveur)
NO : | PASCAL 98-0220474 AIP |
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ET : | Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy |
AU : | BRINKMANN (Ralf); KNIPPER (Ansgar); DROGE (Gerit); SCHROER (Frank); GROMOLL (Bernd); BIRNGRUBER (Reginald) |
AF : | Medical Laser Center Lubeck GmbH, Peter-Monnik-Weg 4, D-23562 Lubeck, Germany (1 aut.); Medical University Lubeck, Clinic of Urology, D-23562 Lubeck, Germany (1 aut.); Medical University Lubeck, Institute of Pathology, D-23562 Lubeck, Germany (1 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Journal of biomedical optics; ISSN 1083-3668; Coden JBOPFO; Etats-Unis; Da. 1998-01; Vol. 3; No. 1; Pp. 85-95 |
LA : | Anglais |
EA : | Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed for different laser and application parameters. The ablation dynamics in water and tissue was investigated by fast flash photography. Uniform cuts could be achieved with 200- and 318-μm fibers using a free-running holmium laser with a pulse repetition rate of 10 Hz and an average power of up to 4 W. The depth of the cuts could be increased by using a thulium laser with the same laser parameters. By reducing the pulse duration by one order of magnitude, the quality of the incisions was made more irregular, the zone of thermomechanical damage increased, and the cuts became deeper owing to the growing influence of cavitation on shorter laser pulse durations. In a first clinical trial, 20 patients underwent holmium laser therapy to reopen ureteral strictures. Neither bleeding nor other adverse effects due to the laser treatment occurred, showing IR laser ureterotomy to be a suitable and promising minimally invasive technique. © 1998 Society of Photo-Optical Instrumentation Engineers. |
CC : | 002A01C; 001D03G02C1 |
FD : | 4262B; 4281; Etude expérimentale; Application médicale laser; Chirurgie; Fibre optique; Découpage |
ED : | Experimental study; Laser applications in medicine; Surgery; Optical fibers; Cutting |
LO : | AIP |
ID : | 98-0220474 |
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Pascal:98-0220474Le document en format XML
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<front><div type="abstract" xml:lang="en">Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed for different laser and application parameters. The ablation dynamics in water and tissue was investigated by fast flash photography. Uniform cuts could be achieved with 200- and 318-μm fibers using a free-running holmium laser with a pulse repetition rate of 10 Hz and an average power of up to 4 W. The depth of the cuts could be increased by using a thulium laser with the same laser parameters. By reducing the pulse duration by one order of magnitude, the quality of the incisions was made more irregular, the zone of thermomechanical damage increased, and the cuts became deeper owing to the growing influence of cavitation on shorter laser pulse durations. In a first clinical trial, 20 patients underwent holmium laser therapy to reopen ureteral strictures. Neither bleeding nor other adverse effects due to the laser treatment occurred, showing IR laser ureterotomy to be a suitable and promising minimally invasive technique. © 1998 Society of Photo-Optical Instrumentation Engineers.</div>
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<ET>Fundamental Studies of Fiber-Guided Soft Tissue Cutting by Means of Pulsed Midinfrared Lasers and their Application in Ureterotomy</ET>
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<EA>Fiber-guided ablation of soft tissue with pulsed holmium and thulium lasers was investigated for intraluminal incisions. A bare fiber/tissue-contact application system with a nearly tangential irradiation geometry was first used in vitro on porcine ureter tissue. The efficiency and precision of the method was analyzed for different laser and application parameters. The ablation dynamics in water and tissue was investigated by fast flash photography. Uniform cuts could be achieved with 200- and 318-μm fibers using a free-running holmium laser with a pulse repetition rate of 10 Hz and an average power of up to 4 W. The depth of the cuts could be increased by using a thulium laser with the same laser parameters. By reducing the pulse duration by one order of magnitude, the quality of the incisions was made more irregular, the zone of thermomechanical damage increased, and the cuts became deeper owing to the growing influence of cavitation on shorter laser pulse durations. In a first clinical trial, 20 patients underwent holmium laser therapy to reopen ureteral strictures. Neither bleeding nor other adverse effects due to the laser treatment occurred, showing IR laser ureterotomy to be a suitable and promising minimally invasive technique. © 1998 Society of Photo-Optical Instrumentation Engineers.</EA>
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