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Optical Stimulation of the Cavernous Nerves in the Rat Prostate

Identifieur interne : 000626 ( Pascal/Corpus ); précédent : 000625; suivant : 000627

Optical Stimulation of the Cavernous Nerves in the Rat Prostate

Auteurs : Nathaniel M. Fried ; Gwen A. Lagoda ; Nicholas J. Scott ; Li-Ming Su ; Arthur L. Bumett

Source :

RBID : Pascal:08-0371370

Descripteurs français

English descriptors

Abstract

Laser nerve stimulation has recently been studied as an alternative to electrical stimulation in neuroscience. Advantages include non-contact stimulation, improved spatial selectivity, and elimination of electrical stimulation artifacts. This study explores laser stimulation of the rat cavernous nerves, as a potential alternative to electrical nerve mapping during nerve-sparing radical prostatectomy. The cavernous nerves were surgically exposed in a total of 10 male rats. A Thulium fiber laser stimulated the nerves, with a wavelength of 1870 nm, pulse energy of 7.5 mJ, radiant exposure of 1 J/cm2, pulse duration of 2.5 ms, pulse rate of 10 Hz, and 1-mm laser spot diameter, for a stimulation time of 60 s. A significant increase in the intracavemosal pressure was detected upon laser stimulation, with pressure returning to baseline levels after stimulation. This study demonstrates the feasibility of non-contact laser stimulation of the cavernous nerves using near-infrared laser radiation.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A01 01  1    @0 1605-7422
A05       @2 6842
A08 01  1  ENG  @1 Optical Stimulation of the Cavernous Nerves in the Rat Prostate
A09 01  1  ENG  @1 Photonic therapeutics and diagnostics IV : 19 January 2008, San Jose, California, USA
A11 01  1    @1 FRIED (Nathaniel M.)
A11 02  1    @1 LAGODA (Gwen A.)
A11 03  1    @1 SCOTT (Nicholas J.)
A11 04  1    @1 SU (Li-Ming)
A11 05  1    @1 BUMETT (Arthur L.)
A12 01  1    @1 KOLLIAS (Nikiforos) @9 ed.
A14 01      @1 Dept. of Physics and Optical Science, University of North Carolina @2 Charlotte, NC @3 USA @Z 1 aut. @Z 3 aut.
A14 02      @1 Department of Urology, Johns Hopkins School of Medicine @2 Baltimore, MD @3 USA @Z 2 aut. @Z 4 aut. @Z 5 aut.
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A43 01      @1 INIST @2 21760 @5 354000172839540260
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
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A47 01  1    @0 08-0371370
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A64 01  1    @0 Progress in biomedical optics and imaging
A66 01      @0 USA
C01 01    ENG  @0 Laser nerve stimulation has recently been studied as an alternative to electrical stimulation in neuroscience. Advantages include non-contact stimulation, improved spatial selectivity, and elimination of electrical stimulation artifacts. This study explores laser stimulation of the rat cavernous nerves, as a potential alternative to electrical nerve mapping during nerve-sparing radical prostatectomy. The cavernous nerves were surgically exposed in a total of 10 male rats. A Thulium fiber laser stimulated the nerves, with a wavelength of 1870 nm, pulse energy of 7.5 mJ, radiant exposure of 1 J/cm2, pulse duration of 2.5 ms, pulse rate of 10 Hz, and 1-mm laser spot diameter, for a stimulation time of 60 s. A significant increase in the intracavemosal pressure was detected upon laser stimulation, with pressure returning to baseline levels after stimulation. This study demonstrates the feasibility of non-contact laser stimulation of the cavernous nerves using near-infrared laser radiation.
C02 01  X    @0 002B01
C03 01  X  FRE  @0 Stimulation @5 02
C03 01  X  ENG  @0 Stimulation @5 02
C03 01  X  SPA  @0 Estimulación @5 02
C03 02  X  FRE  @0 Animal @5 03
C03 02  X  ENG  @0 Animal @5 03
C03 02  X  SPA  @0 Animal @5 03
C03 03  X  FRE  @0 Rat @5 05
C03 03  X  ENG  @0 Rat @5 05
C03 03  X  SPA  @0 Rata @5 05
C03 04  X  FRE  @0 Prostate @5 06
C03 04  X  ENG  @0 Prostate @5 06
C03 04  X  SPA  @0 Prostata @5 06
C03 05  X  FRE  @0 Nerf caverneux @4 CD @5 96
C03 05  X  ENG  @0 Cavernous nerve @4 CD @5 96
C03 05  X  SPA  @0 Nervio cavernoso @4 CD @5 96
C07 01  X  FRE  @0 Rodentia @2 NS
C07 01  X  ENG  @0 Rodentia @2 NS
C07 01  X  SPA  @0 Rodentia @2 NS
C07 02  X  FRE  @0 Mammalia @2 NS
C07 02  X  ENG  @0 Mammalia @2 NS
C07 02  X  SPA  @0 Mammalia @2 NS
C07 03  X  FRE  @0 Vertebrata @2 NS
C07 03  X  ENG  @0 Vertebrata @2 NS
C07 03  X  SPA  @0 Vertebrata @2 NS
N21       @1 238
N44 01      @1 OTO
N82       @1 OTO
pR  
A30 01  1  ENG  @1 Photonic therapeutics and diagnostics. Conference @2 4 @3 San Jose CA USA @4 2008

Format Inist (serveur)

NO : PASCAL 08-0371370 INIST
ET : Optical Stimulation of the Cavernous Nerves in the Rat Prostate
AU : FRIED (Nathaniel M.); LAGODA (Gwen A.); SCOTT (Nicholas J.); SU (Li-Ming); BUMETT (Arthur L.); KOLLIAS (Nikiforos)
AF : Dept. of Physics and Optical Science, University of North Carolina/Charlotte, NC/Etats-Unis (1 aut., 3 aut.); Department of Urology, Johns Hopkins School of Medicine/Baltimore, MD/Etats-Unis (2 aut., 4 aut., 5 aut.)
DT : Publication en série; Congrès; Niveau analytique
SO : Progress in biomedical optics and imaging; ISSN 1605-7422; Etats-Unis; Da. 2008; Vol. 6842; 684213.1-684213.6; Bibl. 23 ref.
LA : Anglais
EA : Laser nerve stimulation has recently been studied as an alternative to electrical stimulation in neuroscience. Advantages include non-contact stimulation, improved spatial selectivity, and elimination of electrical stimulation artifacts. This study explores laser stimulation of the rat cavernous nerves, as a potential alternative to electrical nerve mapping during nerve-sparing radical prostatectomy. The cavernous nerves were surgically exposed in a total of 10 male rats. A Thulium fiber laser stimulated the nerves, with a wavelength of 1870 nm, pulse energy of 7.5 mJ, radiant exposure of 1 J/cm2, pulse duration of 2.5 ms, pulse rate of 10 Hz, and 1-mm laser spot diameter, for a stimulation time of 60 s. A significant increase in the intracavemosal pressure was detected upon laser stimulation, with pressure returning to baseline levels after stimulation. This study demonstrates the feasibility of non-contact laser stimulation of the cavernous nerves using near-infrared laser radiation.
CC : 002B01
FD : Stimulation; Animal; Rat; Prostate; Nerf caverneux
FG : Rodentia; Mammalia; Vertebrata
ED : Stimulation; Animal; Rat; Prostate; Cavernous nerve
EG : Rodentia; Mammalia; Vertebrata
SD : Estimulación; Animal; Rata; Prostata; Nervio cavernoso
LO : INIST-21760.354000172839540260
ID : 08-0371370

Links to Exploration step

Pascal:08-0371370

Le document en format XML

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<LA>Anglais</LA>
<EA>Laser nerve stimulation has recently been studied as an alternative to electrical stimulation in neuroscience. Advantages include non-contact stimulation, improved spatial selectivity, and elimination of electrical stimulation artifacts. This study explores laser stimulation of the rat cavernous nerves, as a potential alternative to electrical nerve mapping during nerve-sparing radical prostatectomy. The cavernous nerves were surgically exposed in a total of 10 male rats. A Thulium fiber laser stimulated the nerves, with a wavelength of 1870 nm, pulse energy of 7.5 mJ, radiant exposure of 1 J/cm
<sup>2</sup>
, pulse duration of 2.5 ms, pulse rate of 10 Hz, and 1-mm laser spot diameter, for a stimulation time of 60 s. A significant increase in the intracavemosal pressure was detected upon laser stimulation, with pressure returning to baseline levels after stimulation. This study demonstrates the feasibility of non-contact laser stimulation of the cavernous nerves using near-infrared laser radiation.</EA>
<CC>002B01</CC>
<FD>Stimulation; Animal; Rat; Prostate; Nerf caverneux</FD>
<FG>Rodentia; Mammalia; Vertebrata</FG>
<ED>Stimulation; Animal; Rat; Prostate; Cavernous nerve</ED>
<EG>Rodentia; Mammalia; Vertebrata</EG>
<SD>Estimulación; Animal; Rata; Prostata; Nervio cavernoso</SD>
<LO>INIST-21760.354000172839540260</LO>
<ID>08-0371370</ID>
</server>
</inist>
</record>

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