ThuliumV1, Pascal, Corpus, bibRecord, 000136

Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions

Identifieur interne : 000136 ( Pascal/Corpus ); précédent : 000135; suivant : 000137

Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions

Auteurs : Marianne Liebi ; Joachim Kohlbrecher ; Takashi Ishikawa ; Peter Fischer ; Peter Walde ; Erich J. Windhab

Source :

Langmuir [ 0743-7463 ] ; 2012.

RBID : Pascal:12-0335971

Descripteurs français

Pascal (Inist)
- Cholestérol, Disque, Complexe, Thulium, Ion, Champ magnétique, Transition phase, Température transition, Microscopie électronique transmission, Diffusion neutron centrale, Phospholipide, Phénomène transitoire.

English descriptors

KwdEn :
- Cholesterol, Complexes, Disk, Ions, Magnetic field, Phase transitions, Phospholipid, Small angle neutron scattering, Thulium, Transients, Transition temperature, Transmission electron microscopy.

Abstract

Aqueous mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-diethylenetriamine pentaacetate (DMPE-DTPA) with complexed thulium ions (Tm³⁺), and cholesterol with varying molar ratio were studied at different temperatures in the presence and absence of a magnetic field. For mixtures without cholesterol weakly magnetically alignable small disks, so-called bicelles, are formed at temperatures below the phase transition temperature (5- 22 °C), as shown by cryo-transmission electron microscopy (cryoTEM) and small-angle neutron scattering (SANS). In presence of 16 mol % cholesterol the disk size and the magnetic alignability were larger within the entire temperature range studied (5-40 °C). Cholesterol acts as a spacer between DMPE-DTPA with complexed Tm³⁺, allowing these molecules to integrate more frequently into the planar part of the bicelles. Replacing DMPC partially by cholesterol thus lead to an increase in magnetic aligning by a higher amount of the magnetic handles (Tm³⁺ complexed to DMPE-DTPA) in the plane and by an increased number of phospholipids in the enlarged bicelles. The magnetic aligning was most pronounced at 5 °C. The temperature-dependent structural changes of the DMPC/cholesterol/DMPE-DTPA/Tm³⁺ aqueous mixtures are complex, including the transient appearance of holes in the disks at intermediate temperatures.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0743-7463`
A02	`01`			`@0 LANGD5`
A03		`1`		`@0 Langmuir`
A05				`@2 28`
A06				`@2 29`
A08	`01`	`1`	`ENG`	`@1 Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions`
A11	`01`	`1`		`@1 LIEBI (Marianne)`
A11	`02`	`1`		`@1 KOHLBRECHER (Joachim)`
A11	`03`	`1`		`@1 ISHIKAWA (Takashi)`
A11	`04`	`1`		`@1 FISCHER (Peter)`
A11	`05`	`1`		`@1 WALDE (Peter)`
A11	`06`	`1`		`@1 WINDHAB (Erich J.)`
A14	`01`			`@1 Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9 @2 8092 Zurich @3 CHE @Z 1 aut. @Z 4 aut. @Z 6 aut.`
A14	`02`			`@1 Laboratory for Neutron Scattering, Paul Scherrer Institute @2 5232 Villigen PSI @3 CHE @Z 2 aut.`
A14	`03`			`@1 Biomolecular Research Laboratory, Paul Scherrer Institute @2 5232 Villigen PSI @3 CHE @Z 3 aut.`
A14	`04`			`@1 Department of Materials, ETH Zurich, Wolfgang-Pauli-Strasse 10 @2 8093 Zurich @3 CHE @Z 5 aut.`
A20				`@1 10905-10915`
A21				`@1 2012`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20642 @5 354000506692590330`
A44				`@0 0000 @1 © 2012 INIST-CNRS. All rights reserved.`
A45				`@0 67 ref.`
A47	`01`	`1`		`@0 12-0335971`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Langmuir`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Aqueous mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-diethylenetriamine pentaacetate (DMPE-DTPA) with complexed thulium ions (Tm³⁺), and cholesterol with varying molar ratio were studied at different temperatures in the presence and absence of a magnetic field. For mixtures without cholesterol weakly magnetically alignable small disks, so-called bicelles, are formed at temperatures below the phase transition temperature (5- 22 °C), as shown by cryo-transmission electron microscopy (cryoTEM) and small-angle neutron scattering (SANS). In presence of 16 mol % cholesterol the disk size and the magnetic alignability were larger within the entire temperature range studied (5-40 °C). Cholesterol acts as a spacer between DMPE-DTPA with complexed Tm³⁺, allowing these molecules to integrate more frequently into the planar part of the bicelles. Replacing DMPC partially by cholesterol thus lead to an increase in magnetic aligning by a higher amount of the magnetic handles (Tm³⁺ complexed to DMPE-DTPA) in the plane and by an increased number of phospholipids in the enlarged bicelles. The magnetic aligning was most pronounced at 5 °C. The temperature-dependent structural changes of the DMPC/cholesterol/DMPE-DTPA/Tm³⁺ aqueous mixtures are complex, including the transient appearance of holes in the disks at intermediate temperatures.
C02	`01`	`X`		`@0 001C01`
C03	`01`	`X`	`FRE`	`@0 Cholestérol @2 NK @5 01`
C03	`01`	`X`	`ENG`	`@0 Cholesterol @2 NK @5 01`
C03	`01`	`X`	`SPA`	`@0 Colesterol @2 NK @5 01`
C03	`02`	`X`	`FRE`	`@0 Disque @5 02`
C03	`02`	`X`	`ENG`	`@0 Disk @5 02`
C03	`02`	`X`	`SPA`	`@0 Disco @5 02`
C03	`03`	`X`	`FRE`	`@0 Complexe @2 NA @5 03`
C03	`03`	`X`	`ENG`	`@0 Complexes @2 NA @5 03`
C03	`03`	`X`	`SPA`	`@0 Complejo @2 NA @5 03`
C03	`04`	`X`	`FRE`	`@0 Thulium @2 NC @5 04`
C03	`04`	`X`	`ENG`	`@0 Thulium @2 NC @5 04`
C03	`04`	`X`	`SPA`	`@0 Tulio @2 NC @5 04`
C03	`05`	`X`	`FRE`	`@0 Ion @2 NA @5 05`
C03	`05`	`X`	`ENG`	`@0 Ions @2 NA @5 05`
C03	`05`	`X`	`SPA`	`@0 Ión @2 NA @5 05`
C03	`06`	`X`	`FRE`	`@0 Champ magnétique @5 06`
C03	`06`	`X`	`ENG`	`@0 Magnetic field @5 06`
C03	`06`	`X`	`SPA`	`@0 Campo magnético @5 06`
C03	`07`	`X`	`FRE`	`@0 Transition phase @5 07`
C03	`07`	`X`	`ENG`	`@0 Phase transitions @5 07`
C03	`07`	`X`	`SPA`	`@0 Transición fase @5 07`
C03	`08`	`X`	`FRE`	`@0 Température transition @5 08`
C03	`08`	`X`	`ENG`	`@0 Transition temperature @5 08`
C03	`08`	`X`	`SPA`	`@0 Temperatura transición @5 08`
C03	`09`	`X`	`FRE`	`@0 Microscopie électronique transmission @5 09`
C03	`09`	`X`	`ENG`	`@0 Transmission electron microscopy @5 09`
C03	`09`	`X`	`SPA`	`@0 Microscopía electrónica transmisión @5 09`
C03	`10`	`X`	`FRE`	`@0 Diffusion neutron centrale @5 10`
C03	`10`	`X`	`ENG`	`@0 Small angle neutron scattering @5 10`
C03	`10`	`X`	`SPA`	`@0 Difusión neutrón central @5 10`
C03	`11`	`X`	`FRE`	`@0 Phospholipide @5 11`
C03	`11`	`X`	`ENG`	`@0 Phospholipid @5 11`
C03	`11`	`X`	`SPA`	`@0 Fosfolípido @5 11`
C03	`12`	`X`	`FRE`	`@0 Phénomène transitoire @5 12`
C03	`12`	`X`	`ENG`	`@0 Transients @5 12`
C03	`12`	`X`	`SPA`	`@0 Fenómeno transitorio @5 12`
N21				`@1 254`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 12-0335971 INIST
ET :	Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions
AU :	LIEBI (Marianne); KOHLBRECHER (Joachim); ISHIKAWA (Takashi); FISCHER (Peter); WALDE (Peter); WINDHAB (Erich J.)
AF :	Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9/8092 Zurich/Suisse (1 aut., 4 aut., 6 aut.); Laboratory for Neutron Scattering, Paul Scherrer Institute/5232 Villigen PSI/Suisse (2 aut.); Biomolecular Research Laboratory, Paul Scherrer Institute/5232 Villigen PSI/Suisse (3 aut.); Department of Materials, ETH Zurich, Wolfgang-Pauli-Strasse 10/8093 Zurich/Suisse (5 aut.)
DT :	Publication en série; Niveau analytique
SO :	Langmuir; ISSN 0743-7463; Coden LANGD5; Etats-Unis; Da. 2012; Vol. 28; No. 29; Pp. 10905-10915; Bibl. 67 ref.
LA :	Anglais
EA :	Aqueous mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-diethylenetriamine pentaacetate (DMPE-DTPA) with complexed thulium ions (Tm³⁺), and cholesterol with varying molar ratio were studied at different temperatures in the presence and absence of a magnetic field. For mixtures without cholesterol weakly magnetically alignable small disks, so-called bicelles, are formed at temperatures below the phase transition temperature (5- 22 °C), as shown by cryo-transmission electron microscopy (cryoTEM) and small-angle neutron scattering (SANS). In presence of 16 mol % cholesterol the disk size and the magnetic alignability were larger within the entire temperature range studied (5-40 °C). Cholesterol acts as a spacer between DMPE-DTPA with complexed Tm³⁺, allowing these molecules to integrate more frequently into the planar part of the bicelles. Replacing DMPC partially by cholesterol thus lead to an increase in magnetic aligning by a higher amount of the magnetic handles (Tm³⁺ complexed to DMPE-DTPA) in the plane and by an increased number of phospholipids in the enlarged bicelles. The magnetic aligning was most pronounced at 5 °C. The temperature-dependent structural changes of the DMPC/cholesterol/DMPE-DTPA/Tm³⁺ aqueous mixtures are complex, including the transient appearance of holes in the disks at intermediate temperatures.
CC :	001C01
FD :	Cholestérol; Disque; Complexe; Thulium; Ion; Champ magnétique; Transition phase; Température transition; Microscopie électronique transmission; Diffusion neutron centrale; Phospholipide; Phénomène transitoire
ED :	Cholesterol; Disk; Complexes; Thulium; Ions; Magnetic field; Phase transitions; Transition temperature; Transmission electron microscopy; Small angle neutron scattering; Phospholipid; Transients
SD :	Colesterol; Disco; Complejo; Tulio; Ión; Campo magnético; Transición fase; Temperatura transición; Microscopía electrónica transmisión; Difusión neutrón central; Fosfolípido; Fenómeno transitorio
LO :	INIST-20642.354000506692590330
ID :	12-0335971

Links to Exploration step

Pascal:12-0335971

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions</title>
<author><name sortKey="Liebi, Marianne" sort="Liebi, Marianne" uniqKey="Liebi M" first="Marianne" last="Liebi">Marianne Liebi</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9</s1>
<s2>8092 Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Kohlbrecher, Joachim" sort="Kohlbrecher, Joachim" uniqKey="Kohlbrecher J" first="Joachim" last="Kohlbrecher">Joachim Kohlbrecher</name>
<affiliation><inist:fA14 i1="02"><s1>Laboratory for Neutron Scattering, Paul Scherrer Institute</s1>
<s2>5232 Villigen PSI</s2>
<s3>CHE</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ishikawa, Takashi" sort="Ishikawa, Takashi" uniqKey="Ishikawa T" first="Takashi" last="Ishikawa">Takashi Ishikawa</name>
<affiliation><inist:fA14 i1="03"><s1>Biomolecular Research Laboratory, Paul Scherrer Institute</s1>
<s2>5232 Villigen PSI</s2>
<s3>CHE</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Fischer, Peter" sort="Fischer, Peter" uniqKey="Fischer P" first="Peter" last="Fischer">Peter Fischer</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9</s1>
<s2>8092 Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Walde, Peter" sort="Walde, Peter" uniqKey="Walde P" first="Peter" last="Walde">Peter Walde</name>
<affiliation><inist:fA14 i1="04"><s1>Department of Materials, ETH Zurich, Wolfgang-Pauli-Strasse 10</s1>
<s2>8093 Zurich</s2>
<s3>CHE</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Windhab, Erich J" sort="Windhab, Erich J" uniqKey="Windhab E" first="Erich J." last="Windhab">Erich J. Windhab</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9</s1>
<s2>8092 Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">12-0335971</idno>
<date when="2012">2012</date>
<idno type="stanalyst">PASCAL 12-0335971 INIST</idno>
<idno type="RBID">Pascal:12-0335971</idno>
<idno type="wicri:Area/Pascal/Corpus">000136</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions</title>
<author><name sortKey="Liebi, Marianne" sort="Liebi, Marianne" uniqKey="Liebi M" first="Marianne" last="Liebi">Marianne Liebi</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9</s1>
<s2>8092 Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Kohlbrecher, Joachim" sort="Kohlbrecher, Joachim" uniqKey="Kohlbrecher J" first="Joachim" last="Kohlbrecher">Joachim Kohlbrecher</name>
<affiliation><inist:fA14 i1="02"><s1>Laboratory for Neutron Scattering, Paul Scherrer Institute</s1>
<s2>5232 Villigen PSI</s2>
<s3>CHE</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ishikawa, Takashi" sort="Ishikawa, Takashi" uniqKey="Ishikawa T" first="Takashi" last="Ishikawa">Takashi Ishikawa</name>
<affiliation><inist:fA14 i1="03"><s1>Biomolecular Research Laboratory, Paul Scherrer Institute</s1>
<s2>5232 Villigen PSI</s2>
<s3>CHE</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Fischer, Peter" sort="Fischer, Peter" uniqKey="Fischer P" first="Peter" last="Fischer">Peter Fischer</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9</s1>
<s2>8092 Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Walde, Peter" sort="Walde, Peter" uniqKey="Walde P" first="Peter" last="Walde">Peter Walde</name>
<affiliation><inist:fA14 i1="04"><s1>Department of Materials, ETH Zurich, Wolfgang-Pauli-Strasse 10</s1>
<s2>8093 Zurich</s2>
<s3>CHE</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Windhab, Erich J" sort="Windhab, Erich J" uniqKey="Windhab E" first="Erich J." last="Windhab">Erich J. Windhab</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9</s1>
<s2>8092 Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Langmuir</title>
<title level="j" type="abbreviated">Langmuir</title>
<idno type="ISSN">0743-7463</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Langmuir</title>
<title level="j" type="abbreviated">Langmuir</title>
<idno type="ISSN">0743-7463</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cholesterol</term>
<term>Complexes</term>
<term>Disk</term>
<term>Ions</term>
<term>Magnetic field</term>
<term>Phase transitions</term>
<term>Phospholipid</term>
<term>Small angle neutron scattering</term>
<term>Thulium</term>
<term>Transients</term>
<term>Transition temperature</term>
<term>Transmission electron microscopy</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cholestérol</term>
<term>Disque</term>
<term>Complexe</term>
<term>Thulium</term>
<term>Ion</term>
<term>Champ magnétique</term>
<term>Transition phase</term>
<term>Température transition</term>
<term>Microscopie électronique transmission</term>
<term>Diffusion neutron centrale</term>
<term>Phospholipide</term>
<term>Phénomène transitoire</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Aqueous mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-diethylenetriamine pentaacetate (DMPE-DTPA) with complexed thulium ions (Tm<sup>3+</sup>
), and cholesterol with varying molar ratio were studied at different temperatures in the presence and absence of a magnetic field. For mixtures without cholesterol weakly magnetically alignable small disks, so-called bicelles, are formed at temperatures below the phase transition temperature (5- 22 °C), as shown by cryo-transmission electron microscopy (cryoTEM) and small-angle neutron scattering (SANS). In presence of 16 mol % cholesterol the disk size and the magnetic alignability were larger within the entire temperature range studied (5-40 °C). Cholesterol acts as a spacer between DMPE-DTPA with complexed Tm<sup>3+</sup>
, allowing these molecules to integrate more frequently into the planar part of the bicelles. Replacing DMPC partially by cholesterol thus lead to an increase in magnetic aligning by a higher amount of the magnetic handles (Tm<sup>3+</sup>
 complexed to DMPE-DTPA) in the plane and by an increased number of phospholipids in the enlarged bicelles. The magnetic aligning was most pronounced at 5 °C. The temperature-dependent structural changes of the DMPC/cholesterol/DMPE-DTPA/Tm<sup>3+</sup>
 aqueous mixtures are complex, including the transient appearance of holes in the disks at intermediate temperatures.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0743-7463</s0>
</fA01>
<fA02 i1="01"><s0>LANGD5</s0>
</fA02>
<fA03 i2="1"><s0>Langmuir</s0>
</fA03>
<fA05><s2>28</s2>
</fA05>
<fA06><s2>29</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>LIEBI (Marianne)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>KOHLBRECHER (Joachim)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>ISHIKAWA (Takashi)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>FISCHER (Peter)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>WALDE (Peter)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>WINDHAB (Erich J.)</s1>
</fA11>
<fA14 i1="01"><s1>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9</s1>
<s2>8092 Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Laboratory for Neutron Scattering, Paul Scherrer Institute</s1>
<s2>5232 Villigen PSI</s2>
<s3>CHE</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Biomolecular Research Laboratory, Paul Scherrer Institute</s1>
<s2>5232 Villigen PSI</s2>
<s3>CHE</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Department of Materials, ETH Zurich, Wolfgang-Pauli-Strasse 10</s1>
<s2>8093 Zurich</s2>
<s3>CHE</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA20><s1>10905-10915</s1>
</fA20>
<fA21><s1>2012</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>20642</s2>
<s5>354000506692590330</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2012 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>67 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>12-0335971</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Langmuir</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Aqueous mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-diethylenetriamine pentaacetate (DMPE-DTPA) with complexed thulium ions (Tm<sup>3+</sup>
), and cholesterol with varying molar ratio were studied at different temperatures in the presence and absence of a magnetic field. For mixtures without cholesterol weakly magnetically alignable small disks, so-called bicelles, are formed at temperatures below the phase transition temperature (5- 22 °C), as shown by cryo-transmission electron microscopy (cryoTEM) and small-angle neutron scattering (SANS). In presence of 16 mol % cholesterol the disk size and the magnetic alignability were larger within the entire temperature range studied (5-40 °C). Cholesterol acts as a spacer between DMPE-DTPA with complexed Tm<sup>3+</sup>
, allowing these molecules to integrate more frequently into the planar part of the bicelles. Replacing DMPC partially by cholesterol thus lead to an increase in magnetic aligning by a higher amount of the magnetic handles (Tm<sup>3+</sup>
 complexed to DMPE-DTPA) in the plane and by an increased number of phospholipids in the enlarged bicelles. The magnetic aligning was most pronounced at 5 °C. The temperature-dependent structural changes of the DMPC/cholesterol/DMPE-DTPA/Tm<sup>3+</sup>
 aqueous mixtures are complex, including the transient appearance of holes in the disks at intermediate temperatures.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>001C01</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Cholestérol</s0>
<s2>NK</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Cholesterol</s0>
<s2>NK</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Colesterol</s0>
<s2>NK</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Disque</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Disk</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Disco</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Complexe</s0>
<s2>NA</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Complexes</s0>
<s2>NA</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Complejo</s0>
<s2>NA</s2>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Thulium</s0>
<s2>NC</s2>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Thulium</s0>
<s2>NC</s2>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Tulio</s0>
<s2>NC</s2>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Ion</s0>
<s2>NA</s2>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Ions</s0>
<s2>NA</s2>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Ión</s0>
<s2>NA</s2>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Champ magnétique</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Magnetic field</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Campo magnético</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Transition phase</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Phase transitions</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Transición fase</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Température transition</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Transition temperature</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Temperatura transición</s0>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Microscopie électronique transmission</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Transmission electron microscopy</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Microscopía electrónica transmisión</s0>
<s5>09</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Diffusion neutron centrale</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Small angle neutron scattering</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Difusión neutrón central</s0>
<s5>10</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Phospholipide</s0>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Phospholipid</s0>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Fosfolípido</s0>
<s5>11</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Phénomène transitoire</s0>
<s5>12</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Transients</s0>
<s5>12</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Fenómeno transitorio</s0>
<s5>12</s5>
</fC03>
<fN21><s1>254</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 12-0335971 INIST</NO>
<ET>Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions</ET>
<AU>LIEBI (Marianne); KOHLBRECHER (Joachim); ISHIKAWA (Takashi); FISCHER (Peter); WALDE (Peter); WINDHAB (Erich J.)</AU>
<AF>Laboratory of Food Process Engineering, ETH Zurich, Schmelzbergstrasse 9/8092 Zurich/Suisse (1 aut., 4 aut., 6 aut.); Laboratory for Neutron Scattering, Paul Scherrer Institute/5232 Villigen PSI/Suisse (2 aut.); Biomolecular Research Laboratory, Paul Scherrer Institute/5232 Villigen PSI/Suisse (3 aut.); Department of Materials, ETH Zurich, Wolfgang-Pauli-Strasse 10/8093 Zurich/Suisse (5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Langmuir; ISSN 0743-7463; Coden LANGD5; Etats-Unis; Da. 2012; Vol. 28; No. 29; Pp. 10905-10915; Bibl. 67 ref.</SO>
<LA>Anglais</LA>
<EA>Aqueous mixtures of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-diethylenetriamine pentaacetate (DMPE-DTPA) with complexed thulium ions (Tm<sup>3+</sup>
), and cholesterol with varying molar ratio were studied at different temperatures in the presence and absence of a magnetic field. For mixtures without cholesterol weakly magnetically alignable small disks, so-called bicelles, are formed at temperatures below the phase transition temperature (5- 22 °C), as shown by cryo-transmission electron microscopy (cryoTEM) and small-angle neutron scattering (SANS). In presence of 16 mol % cholesterol the disk size and the magnetic alignability were larger within the entire temperature range studied (5-40 °C). Cholesterol acts as a spacer between DMPE-DTPA with complexed Tm<sup>3+</sup>
, allowing these molecules to integrate more frequently into the planar part of the bicelles. Replacing DMPC partially by cholesterol thus lead to an increase in magnetic aligning by a higher amount of the magnetic handles (Tm<sup>3+</sup>
 complexed to DMPE-DTPA) in the plane and by an increased number of phospholipids in the enlarged bicelles. The magnetic aligning was most pronounced at 5 °C. The temperature-dependent structural changes of the DMPC/cholesterol/DMPE-DTPA/Tm<sup>3+</sup>
 aqueous mixtures are complex, including the transient appearance of holes in the disks at intermediate temperatures.</EA>
<CC>001C01</CC>
<FD>Cholestérol; Disque; Complexe; Thulium; Ion; Champ magnétique; Transition phase; Température transition; Microscopie électronique transmission; Diffusion neutron centrale; Phospholipide; Phénomène transitoire</FD>
<ED>Cholesterol; Disk; Complexes; Thulium; Ions; Magnetic field; Phase transitions; Transition temperature; Transmission electron microscopy; Small angle neutron scattering; Phospholipid; Transients</ED>
<SD>Colesterol; Disco; Complejo; Tulio; Ión; Campo magnético; Transición fase; Temperatura transición; Microscopía electrónica transmisión; Difusión neutrón central; Fosfolípido; Fenómeno transitorio</SD>
<LO>INIST-20642.354000506692590330</LO>
<ID>12-0335971</ID>
</server>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/ThuliumV1/Data/Pascal/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000136 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Pascal/Corpus/biblio.hfd -nk 000136 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Terre
   |area=    ThuliumV1
   |flux=    Pascal
   |étape=   Corpus
   |type=    RBID
   |clé=     Pascal:12-0335971
   |texte=   Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions
}}

This area was generated with Dilib version V0.6.21.
Data generation: Thu May 12 08:27:09 2016. Site generation: Thu Mar 7 22:33:44 2024

	Serveur d'exploration sur le thulium
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le thulium

Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions

Cholesterol Increases the Magnetic Aligning of Bicellar Disks from an Aqueous Mixture of DMPC and DMPE-DTPA with Complexed Thulium Ions

Source :

Descripteurs français

English descriptors

Abstract

Notice en format standard (ISO 2709)

Format Inist (serveur)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri