Q-switched CTE:YAG laser sclerostomies on human autopsy eyes.
Identifieur interne : 000C37 ( Ncbi/Merge ); précédent : 000C36; suivant : 000C38Q-switched CTE:YAG laser sclerostomies on human autopsy eyes.
Auteurs : O. Kermani [Allemagne] ; H. Lubatschowski ; W. Ertmer ; G K KrieglsteinSource :
- German journal of ophthalmology [ 0941-2921 ] ; 1993.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- methods : Sclerostomy.
- ultrastructure : Eye, Sclera, Trabecular Meshwork.
- Humans, Laser Therapy, Microscopy, Electron, Scanning, Ophthalmologic Surgical Procedures.
Abstract
Experimental laser sclerostomies were performed on human eye-bank eyes with a new mid-infrared solid-state laser that is characterized by adequate optic-fiber transmission and low-thermal tissue interaction. The laser presented herein works with a chromium thulium erbium-doped (CTE): YAG crystal as the active medium, emitting radiation at a wavelength of 2.69 microns. In the Q-switch mode, the pulse duration is tunable from 0.5 to 2.5 microseconds. The maximal energy is 50 mJ/pulse (1-10 Hz). Attenuation of energy transmission in quartz (0.3 ppm) optic fibers is < 8 dB/m (diameter, 200 microns). Absorption depths of 2.69 microns radiation in water is 12.5 microns. In vitro procedures performed were ab-interno and ab-externo full-thickness sclerostomies. Histological and micro-morphological examination was performed by light microscopy and scanning electron microscopy. Collateral tissue damage in processed sclerostomies did not exceed 50(+/- 10) microns at typical fluences (10 J/cm2). In contact guidance, 10-15 laser pulses were required in the full-thickness ab-externo procedure, whereas up to 50 pulses were required in the ab-interno procedure. The number of laser pulses applied corresponded to the length of the filtration canals created. The canal was significantly longer (2.5 +/- 1 mm) in the ab-interno approach than in the ab-externo approach (1 +/- 0.2 mm). The intraocular ostium of the filtration canal in the ab-externo procedure showed enhanced signs of mechanical deterioration. It is concluded that both the wavelength (2.69 microns) and the pulse duration (0.5-2.5 microseconds) of the CTE: YAG laser are appropriate for laser sclerostomy.(ABSTRACT TRUNCATED AT 250 WORDS)
PubMed: 8485435
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<author><name sortKey="Kermani, O" sort="Kermani, O" uniqKey="Kermani O" first="O" last="Kermani">O. Kermani</name>
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<author><name sortKey="Lubatschowski, H" sort="Lubatschowski, H" uniqKey="Lubatschowski H" first="H" last="Lubatschowski">H. Lubatschowski</name>
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<author><name sortKey="Ertmer, W" sort="Ertmer, W" uniqKey="Ertmer W" first="W" last="Ertmer">W. Ertmer</name>
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<author><name sortKey="Krieglstein, G K" sort="Krieglstein, G K" uniqKey="Krieglstein G" first="G K" last="Krieglstein">G K Krieglstein</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Q-switched CTE:YAG laser sclerostomies on human autopsy eyes.</title>
<author><name sortKey="Kermani, O" sort="Kermani, O" uniqKey="Kermani O" first="O" last="Kermani">O. Kermani</name>
<affiliation wicri:level="1"><nlm:affiliation>University Eye Hospital of Cologne, Germany.</nlm:affiliation>
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<term>Microscopy, Electron, Scanning</term>
<term>Ophthalmologic Surgical Procedures</term>
<term>Sclera (ultrastructure)</term>
<term>Sclerostomy (methods)</term>
<term>Trabecular Meshwork (ultrastructure)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term>
<term>Microscopie électronique à balayage</term>
<term>Oeil (ultrastructure)</term>
<term>Procédures de chirurgie ophtalmologique</term>
<term>Réseau trabéculaire de la sclère (ultrastructure)</term>
<term>Sclère (ultrastructure)</term>
<term>Sclérostomie ()</term>
<term>Thérapie laser</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Sclerostomy</term>
</keywords>
<keywords scheme="MESH" qualifier="ultrastructure" xml:lang="en"><term>Eye</term>
<term>Sclera</term>
<term>Trabecular Meshwork</term>
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<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Laser Therapy</term>
<term>Microscopy, Electron, Scanning</term>
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<term>Microscopie électronique à balayage</term>
<term>Oeil</term>
<term>Procédures de chirurgie ophtalmologique</term>
<term>Réseau trabéculaire de la sclère</term>
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<front><div type="abstract" xml:lang="en">Experimental laser sclerostomies were performed on human eye-bank eyes with a new mid-infrared solid-state laser that is characterized by adequate optic-fiber transmission and low-thermal tissue interaction. The laser presented herein works with a chromium thulium erbium-doped (CTE): YAG crystal as the active medium, emitting radiation at a wavelength of 2.69 microns. In the Q-switch mode, the pulse duration is tunable from 0.5 to 2.5 microseconds. The maximal energy is 50 mJ/pulse (1-10 Hz). Attenuation of energy transmission in quartz (0.3 ppm) optic fibers is < 8 dB/m (diameter, 200 microns). Absorption depths of 2.69 microns radiation in water is 12.5 microns. In vitro procedures performed were ab-interno and ab-externo full-thickness sclerostomies. Histological and micro-morphological examination was performed by light microscopy and scanning electron microscopy. Collateral tissue damage in processed sclerostomies did not exceed 50(+/- 10) microns at typical fluences (10 J/cm2). In contact guidance, 10-15 laser pulses were required in the full-thickness ab-externo procedure, whereas up to 50 pulses were required in the ab-interno procedure. The number of laser pulses applied corresponded to the length of the filtration canals created. The canal was significantly longer (2.5 +/- 1 mm) in the ab-interno approach than in the ab-externo approach (1 +/- 0.2 mm). The intraocular ostium of the filtration canal in the ab-externo procedure showed enhanced signs of mechanical deterioration. It is concluded that both the wavelength (2.69 microns) and the pulse duration (0.5-2.5 microseconds) of the CTE: YAG laser are appropriate for laser sclerostomy.(ABSTRACT TRUNCATED AT 250 WORDS)</div>
</front>
</TEI>
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<DateCreated><Year>1993</Year>
<Month>06</Month>
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<Title>German journal of ophthalmology</Title>
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<ArticleTitle>Q-switched CTE:YAG laser sclerostomies on human autopsy eyes.</ArticleTitle>
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<Abstract><AbstractText>Experimental laser sclerostomies were performed on human eye-bank eyes with a new mid-infrared solid-state laser that is characterized by adequate optic-fiber transmission and low-thermal tissue interaction. The laser presented herein works with a chromium thulium erbium-doped (CTE): YAG crystal as the active medium, emitting radiation at a wavelength of 2.69 microns. In the Q-switch mode, the pulse duration is tunable from 0.5 to 2.5 microseconds. The maximal energy is 50 mJ/pulse (1-10 Hz). Attenuation of energy transmission in quartz (0.3 ppm) optic fibers is < 8 dB/m (diameter, 200 microns). Absorption depths of 2.69 microns radiation in water is 12.5 microns. In vitro procedures performed were ab-interno and ab-externo full-thickness sclerostomies. Histological and micro-morphological examination was performed by light microscopy and scanning electron microscopy. Collateral tissue damage in processed sclerostomies did not exceed 50(+/- 10) microns at typical fluences (10 J/cm2). In contact guidance, 10-15 laser pulses were required in the full-thickness ab-externo procedure, whereas up to 50 pulses were required in the ab-interno procedure. The number of laser pulses applied corresponded to the length of the filtration canals created. The canal was significantly longer (2.5 +/- 1 mm) in the ab-interno approach than in the ab-externo approach (1 +/- 0.2 mm). The intraocular ostium of the filtration canal in the ab-externo procedure showed enhanced signs of mechanical deterioration. It is concluded that both the wavelength (2.69 microns) and the pulse duration (0.5-2.5 microseconds) of the CTE: YAG laser are appropriate for laser sclerostomy.(ABSTRACT TRUNCATED AT 250 WORDS)</AbstractText>
</Abstract>
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