Serveur d'exploration sur le thulium

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Complications and early postoperative outcome in 1080 patients after thulium vapoenucleation of the prostate: results at a single institution.

Identifieur interne : 000634 ( Ncbi/Merge ); précédent : 000633; suivant : 000635

Complications and early postoperative outcome in 1080 patients after thulium vapoenucleation of the prostate: results at a single institution.

Auteurs : Andreas J. Gross [Allemagne] ; Christopher Netsch ; Sophie Knipper ; Jasmin Hölzel ; Thorsten Bach

Source :

RBID : pubmed:23245687

Descripteurs français

English descriptors

Abstract

Thulium vapoenucleation of the prostate (ThuVEP) has been introduced as a minimally invasive treatment for benign prostatic obstruction (BPO).

DOI: 10.1016/j.eururo.2012.11.048
PubMed: 23245687

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pubmed:23245687

Le document en format XML

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<div type="abstract" xml:lang="en">Thulium vapoenucleation of the prostate (ThuVEP) has been introduced as a minimally invasive treatment for benign prostatic obstruction (BPO).</div>
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<ArticleTitle>Complications and early postoperative outcome in 1080 patients after thulium vapoenucleation of the prostate: results at a single institution.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Thulium vapoenucleation of the prostate (ThuVEP) has been introduced as a minimally invasive treatment for benign prostatic obstruction (BPO).</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To analyze immediate outcomes and the institutional learning curve of ThuVEP, and to report its standardized complication rates, using the modified Clavien classification system (CCS) to grade perioperative complication rates.</AbstractText>
<AbstractText Label="DESIGN, SETTINGS, AND PARTICIPANTS" NlmCategory="METHODS">A prospective evaluation of 1080 patients undergoing ThuVEP from January 2007 until May 2012 at our institution.</AbstractText>
<AbstractText Label="INTERVENTION" NlmCategory="METHODS">ThuVEP was performed using the 2-μm, continuous-wave, thulium:yttrium-aluminum-garnet laser.</AbstractText>
<AbstractText Label="OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS" NlmCategory="METHODS">Preoperative status, surgical details, and immediate outcome were recorded for each patient. Perioperative complications were classified according to the modified CCS.</AbstractText>
<AbstractText Label="RESULTS AND LIMITATIONS" NlmCategory="CONCLUSIONS">Median prostate size was 51 ml (interquartile range [IQR]: 36-78.7). Median operation time was 56 min (IQR: 40-80), and median enucleation time was 32.5 min (IQR: 22-50). Median catheterization time was 2 d (IQR: 2-2); median length of hospital stay was 4 d (IQR: 3-5). Median resected tissue weight was 30 g (IQR: 16.00-51.25). Incidental carcinoma of the prostate was detected in 59 (5.5%) patients. Median maximum urinary flow rate (8.9 vs 18.4 ml/s) and postvoid residual urine volume (120 vs 20 ml) changed significantly (p<0.001). Minor complications occurred in 24.6% of the patients (Clavien 1: 20.8%; Clavien 2: 3.8%). Early reinterventions were necessary in 6.6% of the patients (Clavien 3a: 0.6%; Clavien 3b: 6%). One Clavien 4 complication occurred (0.09%). The overall complication rates decreased significantly over time due to decreasing Clavien 1, 2, and 3b events. The major limitations of the study are the prospective, unicentric study design, the lack of a control group, and that only short-term data were documented on morbidity and efficacy of the ThuVEP procedure.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">ThuVEP is a safe and effective procedure for the treatment of symptomatic BPO, with low perioperative morbidity.</AbstractText>
<CopyrightInformation>Copyright © 2012 European Association of Urology. Published by Elsevier B.V. All rights reserved.</CopyrightInformation>
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