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120-W 2-µm thulium:yttrium-aluminium-garnet vapoenucleation of the prostate: 12-month follow-up.

Identifieur interne : 000516 ( Ncbi/Merge ); précédent : 000515; suivant : 000517

120-W 2-µm thulium:yttrium-aluminium-garnet vapoenucleation of the prostate: 12-month follow-up.

Auteurs : Christopher Netsch [Allemagne] ; Laura Pohlmann ; Thomas R W. Herrmann ; Andreas J. Gross ; Thorsten Bach

Source :

RBID : pubmed:22085294

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English descriptors

Abstract

Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Thulium VapoEnucleation of the prostate (ThuVEP) has been introduced as a minimally invasive treatment modality of benign prostate obstruction (BPO). This study reports the largest series of patients with symptomatic BPO undergoing ThuVEP. Efficacy of this procedure was confirmed by prostate volume and PSA measurements at 12-month follow up, which have not been reported after ThuVEP so far.

DOI: 10.1111/j.1464-410X.2011.10767.x
PubMed: 22085294

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pubmed:22085294

Le document en format XML

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<term>Lasers, Solid-State (therapeutic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prostate (pathology)</term>
<term>Prostatic Hyperplasia (diagnosis)</term>
<term>Prostatic Hyperplasia (pathology)</term>
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<term>Adulte d'âge moyen</term>
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<term>Hyperplasie de la prostate ()</term>
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<div type="abstract" xml:lang="en">Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Thulium VapoEnucleation of the prostate (ThuVEP) has been introduced as a minimally invasive treatment modality of benign prostate obstruction (BPO). This study reports the largest series of patients with symptomatic BPO undergoing ThuVEP. Efficacy of this procedure was confirmed by prostate volume and PSA measurements at 12-month follow up, which have not been reported after ThuVEP so far.</div>
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<DateCreated>
<Year>2012</Year>
<Month>06</Month>
<Day>13</Day>
</DateCreated>
<DateCompleted>
<Year>2012</Year>
<Month>09</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1464-410X</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>110</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2012</Year>
<Month>Jul</Month>
</PubDate>
</JournalIssue>
<Title>BJU international</Title>
<ISOAbbreviation>BJU Int.</ISOAbbreviation>
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<ArticleTitle>120-W 2-µm thulium:yttrium-aluminium-garnet vapoenucleation of the prostate: 12-month follow-up.</ArticleTitle>
<Pagination>
<MedlinePgn>96-101</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1464-410X.2011.10767.x</ELocationID>
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<AbstractText Label="UNLABELLED">Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Thulium VapoEnucleation of the prostate (ThuVEP) has been introduced as a minimally invasive treatment modality of benign prostate obstruction (BPO). This study reports the largest series of patients with symptomatic BPO undergoing ThuVEP. Efficacy of this procedure was confirmed by prostate volume and PSA measurements at 12-month follow up, which have not been reported after ThuVEP so far.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate the safety and efficacy of 120-W 2-µm thulium:yttrium-aluminium-garnet (YAG) vapoenucleation of the prostate (ThuVEP) for patients with symptomatic benign prostatic obstruction.</AbstractText>
<AbstractText Label="METHOD" NlmCategory="METHODS">In total, 207 consecutive patients undergoing ThuVEP at our institution were evaluated prospectively. ThuVEP was carried out using the 120-W 2-µm continuous-wave Tm:YAG laser. The enucleated tissue was then morcellated within the bladder. Patient demographic, perioperative and 12-month follow-up data were analysed. The complications were assessed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Mean preoperative prostate volume was 57.8 ± 31.5 mL. Total operation duration averaged 64.9 ± 29.9 min, and the enucleation time was 36.5 ± 20.1 min. The mean catheter time was 2.2 ± 0.6 days. Thirteen (6.28%) patients required a second-look operation in the immediate postoperative course (failed morcellation n= 1, clot retention n= 4, residual tissue at the apex of the prostate n= 8). Four patients needed blood transfusions (1.93%) postoperatively. In all, 147 (71%) patients were available for review at the 12-month follow-up mark. Quality of life (4.4 ± 1.3 vs 1.2 ± 1.1), international prostate symptom score (21.9 ± 7.2 vs 5.1 ± 4), maximum urinary flow rate (9.4 ± 3.8 vs 23.5 ± 10.9 mL/s), postvoiding residual urine (159.2 ± 153.2 vs 26.7 ± 38.3 mL), prostate-specific antigen (5.0 ± 5.2 vs 0.6 ± 0.5 ng/mL) and prostate volume (57.8 ± 31.5 vs 10.7 ± 4.4 mL) changed significantly (P= 0.000). Median prostate-specific antigen reduction and prostate volume reduction were 87% and 80% respectively at follow-up. Urethral stricture and bladder neck contracture developed in 1.45% and 1.93% respectively of the patients.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">120-W ThuVEP is a safe and efficacious procedure for the treatment of symptomatic benign prostatic obstruction. The incidence of complications with ThuVEP was low.</AbstractText>
<CopyrightInformation>© 2011 BJU INTERNATIONAL.</CopyrightInformation>
</Abstract>
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<RefSource>J Urol. 2013 Aug;190(2):626</RefSource>
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<RefSource>BJU Int. 2012 Jul;110(1):101</RefSource>
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