Effect of Laser Thermal Injury on Langerhans Cells in Mouse and Hairless Guinea Pig Epidermis
Identifieur interne : 000588 ( Main/Exploration ); précédent : 000587; suivant : 000589Effect of Laser Thermal Injury on Langerhans Cells in Mouse and Hairless Guinea Pig Epidermis
Auteurs : Kim Burnham [États-Unis] ; Kurt Schuster ; Aurora Shingledecker ; Robert Kornegay ; Jeffrey OliverSource :
- Photochemistry and Photobiology [ 0031-8655 ] ; 2013-09.
Descripteurs français
- KwdFr :
- MESH :
- cytologie : Épiderme.
- effets des radiations : Cellules de Langerhans, Épiderme.
- métabolisme : Adenosine triphosphatases, Antigènes d'histocompatibilité de classe II.
- Wicri :
- geographic : Animaux, Cochons d'Inde, Femelle, Guinée, Lasers, Souris, Souris de lignée BALB C.
- topic : Migration.
English descriptors
- KwdEn :
- Adenosine Triphosphatases (metabolism), Animals, Coagulation, Collagen denaturation, Dendritic, Dermal, Dermal damage, Dermis, Epidermal, Epidermal damage, Epidermis, Epidermis (cytology), Epidermis (radiation effects), Female, Guinea, Guinea Pigs, Hairless, Hairless guinea, Hairless guinea pigs, Highest dose, Histocompatibility Antigens Class II (metabolism), Human skin, Infectious agents, Infrared camera, Langerhans, Langerhans Cells (radiation effects), Langerhans cells, Laser, Laser exposure, Laser irradiation, Laser treatment, Lasers, Mice, Mice, Inbred BALB C, Migration, Mouse, Mouse skin, Normal levels, Peak temperature increase, Post exposure, Post irradiation, Separate power settings, Standard error, Thermal damage, Tissue damage, Unexposed skin, Viable epidermis.
- MESH :
- chemical , metabolism : Adenosine Triphosphatases, Histocompatibility Antigens Class II.
- cytology : Epidermis.
- radiation effects : Epidermis, Langerhans Cells.
- Teeft :
- Animals, Coagulation, Collagen denaturation, Dendritic, Dermal, Dermal damage, Dermis, Epidermal, Epidermal damage, Epidermis, Female, Guinea, Guinea Pigs, Hairless, Hairless guinea, Hairless guinea pigs, Highest dose, Human skin, Infectious agents, Infrared camera, Langerhans, Langerhans cells, Laser, Laser exposure, Laser irradiation, Laser treatment, Lasers, Mice, Mice, Inbred BALB C, Migration, Mouse, Mouse skin, Normal levels, Peak temperature increase, Post exposure, Post irradiation, Separate power settings, Standard error, Thermal damage, Tissue damage, Unexposed skin, Viable epidermis.
Abstract
To examine the effect of laser thermal injury on Langerhans cells (LC) within the epidermis, the dorsal skin of mice and hairless guinea pigs was exposed to varying levels of laser irradiation using a thulium laser at a wavelength of 2.0 μm. At 6, 24 and 48 h post irradiation, animals were euthanized, skin samples prepared for histology and the epidermis obtained and stained by major histocompatibility complex‐II staining (mice) or ATPase assay (hairless guinea pigs) for the enumeration of LC. Mouse skin exhibited histological evidence of thermal damage at 24 h post irradiation at even the lowest dose (0.14 W) and decreases in the numbers of epidermal LC were observed at all doses and decreases were proportional to dose. In contrast, hairless guinea pig skin only showed consistent histological evidence of thermal damage at the highest dose of irradiation (0.70 W) at 24 and 48 h post irradiation and exhibited a statistically significant decrease in numbers of epidermal LC only at this dose. Thus, epidermal LC depletion occurred in the skin of both mice and hairless guinea pigs in response to laser treatment and the magnitude of depletion directly correlated with the extent of thermal damage both within and between species.
Url:
DOI: 10.1111/php.12092
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002F17
- to stream Istex, to step Curation: 002F17
- to stream Istex, to step Checkpoint: 000045
- to stream PubMed, to step Corpus: 000282
- to stream PubMed, to step Curation: 000282
- to stream PubMed, to step Checkpoint: 000282
- to stream Ncbi, to step Merge: 000684
- to stream Ncbi, to step Curation: 000684
- to stream Ncbi, to step Checkpoint: 000684
- to stream Main, to step Merge: 000588
- to stream Main, to step Curation: 000588
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of Laser Thermal Injury on Langerhans Cells in Mouse and Hairless Guinea Pig Epidermis</title><author><name sortKey="Burnham, Kim" sort="Burnham, Kim" uniqKey="Burnham K" first="Kim" last="Burnham">Kim Burnham</name></author><author><name sortKey="Schuster, Kurt" sort="Schuster, Kurt" uniqKey="Schuster K" first="Kurt" last="Schuster">Kurt Schuster</name></author><author><name sortKey="Shingledecker, Aurora" sort="Shingledecker, Aurora" uniqKey="Shingledecker A" first="Aurora" last="Shingledecker">Aurora Shingledecker</name></author><author><name sortKey="Kornegay, Robert" sort="Kornegay, Robert" uniqKey="Kornegay R" first="Robert" last="Kornegay">Robert Kornegay</name></author><author><name sortKey="Oliver, Jeffrey" sort="Oliver, Jeffrey" uniqKey="Oliver J" first="Jeffrey" last="Oliver">Jeffrey Oliver</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D5781CEB6336A6B1C0CAAFAABB7857A5DD64D9E4</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1111/php.12092</idno><idno type="url">https://api.istex.fr/document/D5781CEB6336A6B1C0CAAFAABB7857A5DD64D9E4/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002F17</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002F17</idno><idno type="wicri:Area/Istex/Curation">002F17</idno><idno type="wicri:Area/Istex/Checkpoint">000045</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000045</idno><idno type="wicri:doubleKey">0031-8655:2013:Burnham K:effect:of:laser</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:23663071</idno><idno type="wicri:Area/PubMed/Corpus">000282</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000282</idno><idno type="wicri:Area/PubMed/Curation">000282</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000282</idno><idno type="wicri:Area/PubMed/Checkpoint">000282</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000282</idno><idno type="wicri:Area/Ncbi/Merge">000684</idno><idno type="wicri:Area/Ncbi/Curation">000684</idno><idno type="wicri:Area/Ncbi/Checkpoint">000684</idno><idno type="wicri:Area/Main/Merge">000588</idno><idno type="wicri:Area/Main/Curation">000588</idno><idno type="wicri:Area/Main/Exploration">000588</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Effect of Laser Thermal Injury on Langerhans Cells in Mouse and Hairless Guinea Pig Epidermis</title><author><name sortKey="Burnham, Kim" sort="Burnham, Kim" uniqKey="Burnham K" first="Kim" last="Burnham">Kim Burnham</name><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author><author><name sortKey="Schuster, Kurt" sort="Schuster, Kurt" uniqKey="Schuster K" first="Kurt" last="Schuster">Kurt Schuster</name><affiliation><wicri:noCountry code="subField">Houston</wicri:noCountry></affiliation></author><author><name sortKey="Shingledecker, Aurora" sort="Shingledecker, Aurora" uniqKey="Shingledecker A" first="Aurora" last="Shingledecker">Aurora Shingledecker</name><affiliation><wicri:noCountry code="subField">Houston</wicri:noCountry></affiliation></author><author><name sortKey="Kornegay, Robert" sort="Kornegay, Robert" uniqKey="Kornegay R" first="Robert" last="Kornegay">Robert Kornegay</name><affiliation><wicri:noCountry code="subField">Houston</wicri:noCountry></affiliation></author><author><name sortKey="Oliver, Jeffrey" sort="Oliver, Jeffrey" uniqKey="Oliver J" first="Jeffrey" last="Oliver">Jeffrey Oliver</name><affiliation><wicri:noCountry code="subField">Houston</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Photochemistry and Photobiology</title><title level="j" type="alt">PHOTOCHEMISTRY AND PHOTOBIOLOGY</title><idno type="ISSN">0031-8655</idno><idno type="eISSN">1751-1097</idno><imprint><biblScope unit="vol">89</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="1249">1249</biblScope><biblScope unit="page" to="1254">1254</biblScope><biblScope unit="page-count">6</biblScope><date type="published" when="2013-09">2013-09</date></imprint><idno type="ISSN">0031-8655</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0031-8655</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenosine Triphosphatases (metabolism)</term><term>Animals</term><term>Coagulation</term><term>Collagen denaturation</term><term>Dendritic</term><term>Dermal</term><term>Dermal damage</term><term>Dermis</term><term>Epidermal</term><term>Epidermal damage</term><term>Epidermis</term><term>Epidermis (cytology)</term><term>Epidermis (radiation effects)</term><term>Female</term><term>Guinea</term><term>Guinea Pigs</term><term>Hairless</term><term>Hairless guinea</term><term>Hairless guinea pigs</term><term>Highest dose</term><term>Histocompatibility Antigens Class II (metabolism)</term><term>Human skin</term><term>Infectious agents</term><term>Infrared camera</term><term>Langerhans</term><term>Langerhans Cells (radiation effects)</term><term>Langerhans cells</term><term>Laser</term><term>Laser exposure</term><term>Laser irradiation</term><term>Laser treatment</term><term>Lasers</term><term>Mice</term><term>Mice, Inbred BALB C</term><term>Migration</term><term>Mouse</term><term>Mouse skin</term><term>Normal levels</term><term>Peak temperature increase</term><term>Post exposure</term><term>Post irradiation</term><term>Separate power settings</term><term>Standard error</term><term>Thermal damage</term><term>Tissue damage</term><term>Unexposed skin</term><term>Viable epidermis</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adenosine triphosphatases (métabolisme)</term><term>Animaux</term><term>Antigènes d'histocompatibilité de classe II (métabolisme)</term><term>Cellules de Langerhans (effets des radiations)</term><term>Cochons d'Inde</term><term>Femelle</term><term>Lasers</term><term>Souris</term><term>Souris de lignée BALB C</term><term>Épiderme (cytologie)</term><term>Épiderme (effets des radiations)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Adenosine Triphosphatases</term><term>Histocompatibility Antigens Class II</term></keywords><keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Épiderme</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Epidermis</term></keywords><keywords scheme="MESH" qualifier="effets des radiations" xml:lang="fr"><term>Cellules de Langerhans</term><term>Épiderme</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Adenosine triphosphatases</term><term>Antigènes d'histocompatibilité de classe II</term></keywords><keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Epidermis</term><term>Langerhans Cells</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Animals</term><term>Coagulation</term><term>Collagen denaturation</term><term>Dendritic</term><term>Dermal</term><term>Dermal damage</term><term>Dermis</term><term>Epidermal</term><term>Epidermal damage</term><term>Epidermis</term><term>Female</term><term>Guinea</term><term>Guinea Pigs</term><term>Hairless</term><term>Hairless guinea</term><term>Hairless guinea pigs</term><term>Highest dose</term><term>Human skin</term><term>Infectious agents</term><term>Infrared camera</term><term>Langerhans</term><term>Langerhans cells</term><term>Laser</term><term>Laser exposure</term><term>Laser irradiation</term><term>Laser treatment</term><term>Lasers</term><term>Mice</term><term>Mice, Inbred BALB C</term><term>Migration</term><term>Mouse</term><term>Mouse skin</term><term>Normal levels</term><term>Peak temperature increase</term><term>Post exposure</term><term>Post irradiation</term><term>Separate power settings</term><term>Standard error</term><term>Thermal damage</term><term>Tissue damage</term><term>Unexposed skin</term><term>Viable epidermis</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Animaux</term><term>Cochons d'Inde</term><term>Femelle</term><term>Guinée</term><term>Lasers</term><term>Souris</term><term>Souris de lignée BALB C</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Migration</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">To examine the effect of laser thermal injury on Langerhans cells (LC) within the epidermis, the dorsal skin of mice and hairless guinea pigs was exposed to varying levels of laser irradiation using a thulium laser at a wavelength of 2.0 μm. At 6, 24 and 48 h post irradiation, animals were euthanized, skin samples prepared for histology and the epidermis obtained and stained by major histocompatibility complex‐II staining (mice) or ATPase assay (hairless guinea pigs) for the enumeration of LC. Mouse skin exhibited histological evidence of thermal damage at 24 h post irradiation at even the lowest dose (0.14 W) and decreases in the numbers of epidermal LC were observed at all doses and decreases were proportional to dose. In contrast, hairless guinea pig skin only showed consistent histological evidence of thermal damage at the highest dose of irradiation (0.70 W) at 24 and 48 h post irradiation and exhibited a statistically significant decrease in numbers of epidermal LC only at this dose. Thus, epidermal LC depletion occurred in the skin of both mice and hairless guinea pigs in response to laser treatment and the magnitude of depletion directly correlated with the extent of thermal damage both within and between species.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Kornegay, Robert" sort="Kornegay, Robert" uniqKey="Kornegay R" first="Robert" last="Kornegay">Robert Kornegay</name><name sortKey="Oliver, Jeffrey" sort="Oliver, Jeffrey" uniqKey="Oliver J" first="Jeffrey" last="Oliver">Jeffrey Oliver</name><name sortKey="Schuster, Kurt" sort="Schuster, Kurt" uniqKey="Schuster K" first="Kurt" last="Schuster">Kurt Schuster</name><name sortKey="Shingledecker, Aurora" sort="Shingledecker, Aurora" uniqKey="Shingledecker A" first="Aurora" last="Shingledecker">Aurora Shingledecker</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Burnham, Kim" sort="Burnham, Kim" uniqKey="Burnham K" first="Kim" last="Burnham">Kim Burnham</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/ThuliumV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000588 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000588 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Terre
|area= ThuliumV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:D5781CEB6336A6B1C0CAAFAABB7857A5DD64D9E4
|texte= Effect of Laser Thermal Injury on Langerhans Cells in Mouse and Hairless Guinea Pig Epidermis
}}
| This area was generated with Dilib version V0.6.21. |  |