ThuliumV1, Main, Exploration, bibRecordById, pubmed:20443484

Study of encapsulated 170Tm sources for their potential use in brachytherapy.

Identifieur interne : 000C15 ( Main/Exploration ); précédent : 000C14; suivant : 000C16

Study of encapsulated 170Tm sources for their potential use in brachytherapy.

Auteurs : Facundo Ballester [Espagne] ; Domingo Granero ; Jose Perez-Calatayud ; Jack L M. Venselaar ; Mark J. Rivard

Source :

Medical physics [ 0094-2405 ] ; 2010.

RBID : pubmed:20443484

Descripteurs français

KwdFr :
- Curiethérapie (), Humains, Logiciel, Méthode de Monte-Carlo, Neutrons, Photons, Platine (), Radio-isotopes (usage thérapeutique), Radio-isotopes de l'iridium (usage thérapeutique), Radiométrie (), Radiothérapie (), Thulium (usage thérapeutique), Ytterbium (usage thérapeutique), Électrons.
MESH :
- usage thérapeutique : Radio-isotopes, Radio-isotopes de l'iridium, Thulium, Ytterbium.
- Curiethérapie, Humains, Logiciel, Méthode de Monte-Carlo, Neutrons, Photons, Platine, Radiométrie, Radiothérapie, Électrons.

English descriptors

KwdEn :
- Brachytherapy (methods), Electrons, Humans, Iridium Radioisotopes (therapeutic use), Monte Carlo Method, Neutrons, Photons, Platinum (chemistry), Radioisotopes (therapeutic use), Radiometry (methods), Radiotherapy (methods), Software, Thulium (therapeutic use), Ytterbium (therapeutic use).
MESH :
- chemical , chemistry : Platinum.
- chemical , therapeutic use : Iridium Radioisotopes, Radioisotopes, Thulium, Ytterbium.
- methods : Brachytherapy, Radiometry, Radiotherapy.
- Electrons, Humans, Monte Carlo Method, Neutrons, Photons, Software.

Abstract

High dose-rate (HDR) brachytherapy is currently performed with 192Ir sources, and 60Co has returned recently into clinical use as a source for this kind of cancer treatment. Both radionuclides have mean photon energies high enough to require specific shielded treatment rooms. In recent years, 169Yb has been explored as an alternative for HDR-brachytherapy implants. Although it has mean photon energy lower than 192Ir, it still requires extensive shielding to deliver treatment. An alternative radionuclide for brachytherapy is 170Tm (Z=69) because it has three physical properties adequate for clinical practice: (a) 128.6 day half-life, (b) high specific activity, and (c) mean photon energy of 66.39 keV. The main drawback of this radionuclide is the low photon yield (six photons per 100 electrons emitted). The purpose of this work is to study the dosimetric characteristics of this radionuclide for potential use in HDR-brachytherapy.

DOI: 10.1118/1.3360441
PubMed: 20443484

Affiliations:

Espagne

Le document en format XML

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<author><name sortKey="Perez Calatayud, Jose" sort="Perez Calatayud, Jose" uniqKey="Perez Calatayud J" first="Jose" last="Perez-Calatayud">Jose Perez-Calatayud</name>
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<author><name sortKey="Venselaar, Jack L M" sort="Venselaar, Jack L M" uniqKey="Venselaar J" first="Jack L M" last="Venselaar">Jack L M. Venselaar</name>
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<term>Monte Carlo Method</term>
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<term>Photons</term>
<term>Platinum (chemistry)</term>
<term>Radioisotopes (therapeutic use)</term>
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<term>Ytterbium</term>
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<front><div type="abstract" xml:lang="en">High dose-rate (HDR) brachytherapy is currently performed with 192Ir sources, and 60Co has returned recently into clinical use as a source for this kind of cancer treatment. Both radionuclides have mean photon energies high enough to require specific shielded treatment rooms. In recent years, 169Yb has been explored as an alternative for HDR-brachytherapy implants. Although it has mean photon energy lower than 192Ir, it still requires extensive shielding to deliver treatment. An alternative radionuclide for brachytherapy is 170Tm (Z=69) because it has three physical properties adequate for clinical practice: (a) 128.6 day half-life, (b) high specific activity, and (c) mean photon energy of 66.39 keV. The main drawback of this radionuclide is the low photon yield (six photons per 100 electrons emitted). The purpose of this work is to study the dosimetric characteristics of this radionuclide for potential use in HDR-brachytherapy.</div>
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<name sortKey="Rivard, Mark J" sort="Rivard, Mark J" uniqKey="Rivard M" first="Mark J" last="Rivard">Mark J. Rivard</name>
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<country name="Espagne"><noRegion><name sortKey="Ballester, Facundo" sort="Ballester, Facundo" uniqKey="Ballester F" first="Facundo" last="Ballester">Facundo Ballester</name>
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Study of encapsulated 170Tm sources for their potential use in brachytherapy.

Study of encapsulated 170Tm sources for their potential use in brachytherapy.

Source :

Descripteurs français

English descriptors

Abstract

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