Idiopathic cerebrospinal fluid overproduction: case-based review of the pathophysiological mechanism implied in the cerebrospinal fluid production
Identifieur interne : 000300 ( Main/Exploration ); précédent : 000299; suivant : 000301Idiopathic cerebrospinal fluid overproduction: case-based review of the pathophysiological mechanism implied in the cerebrospinal fluid production
Auteurs : Gianluca Trevisi ; Paolo Frassanito ; Concezio Di RoccoSource :
- Croatian Medical Journal [ 0353-9504 ] ; 2014.
Abstract
Cerebrospinal fluid (CSF) overproduction results from either CSF infection or choroid plexus hypertrophy or tumor, with only a single idiopathic case described so far. We report a unique case of a male infant with Crouzon syndrome who presented with intracranial hypertension, caused by up to 4-fold increase in CSF daily production. Conditions related to CSF overproduction, namely central nervous system infections and choroid plexus hypertrophy or tumor, were ruled out by repeated magnetic resonance imaging and CSF samples. Medical therapy failed to reduce CSF production and the patient underwent several shunting procedures, cranial expansion, and endoscopic coagulation of the choroid plexus. This article thoroughly reviews pertinent literature on CSF production mechanisms and possible therapeutic implications.
Url:
DOI: 10.3325/cmj.2014.55.377
PubMed: 25165051
PubMed Central: 4157373
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We report a unique case of a male infant with Crouzon syndrome who presented with intracranial hypertension, caused by up to 4-fold increase in CSF daily production. Conditions related to CSF overproduction, namely central nervous system infections and choroid plexus hypertrophy or tumor, were ruled out by repeated magnetic resonance imaging and CSF samples. Medical therapy failed to reduce CSF production and the patient underwent several shunting procedures, cranial expansion, and endoscopic coagulation of the choroid plexus. 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Rockey</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Di Rocco, Concezio" sort="Di Rocco, Concezio" uniqKey="Di Rocco C" first="Concezio" last="Di Rocco">Concezio Di Rocco</name><name sortKey="Frassanito, Paolo" sort="Frassanito, Paolo" uniqKey="Frassanito P" first="Paolo" last="Frassanito">Paolo Frassanito</name><name sortKey="Trevisi, Gianluca" sort="Trevisi, Gianluca" uniqKey="Trevisi G" first="Gianluca" last="Trevisi">Gianluca Trevisi</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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