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OPTICS OF CONDUCTIVE KERATOPLASTY: IMPLICATIONS FOR PRESBYOPIA MANAGEMENT

Identifieur interne : 001857 ( Main/Exploration ); précédent : 001856; suivant : 001858

OPTICS OF CONDUCTIVE KERATOPLASTY: IMPLICATIONS FOR PRESBYOPIA MANAGEMENT

Auteurs : Peter S. Hersh

Source :

RBID : PMC:1447583

Abstract

Purpose

To define the corneal optics of conductive keratoplasty (CK) and assess the clinical implications for hyperopia and presbyopia management.

Methods

Four analyses were done. (1) Multifocal effects: In a prospective study of CK, uncorrected visual acuity (UCVA) for a given refractive error in 72 postoperative eyes was compared to control eyes. (2) Surgically induced astigmatism (SIA): 203 eyes were analyzed for magnitude and axis of SIA. (3) Higher-order optical aberrations: Corneal higher-order optical aberrations were assessed for 36 eyes after CK and a similar patient population after hyperopic laser in situ keratomileusis (LASIK). (4) Presbyopia clinical trial: Visual acuity, refractive result, and patient questionnaires were analyzed for 150 subjects in a prospective, multicenter clinical trial of presbyopia management with CK.

Results

(1) 63% and 82% of eyes after CK had better UCVA at distance and near, respectively, than controls. (2) The mean SIA was 0.23 diopter (D) steepening at 175° (P < .001); mean magnitude was 0.66 D (SD, 0.43 D). (3) After CK, composite fourth- and sixth-order spherical aberration increased; change in (Z12) spherical aberration alone was not statistically significant. When compared to hyperopic LASIK, there was a statistically significant increase in composite fourth- and sixth-order spherical aberration (P < .01) and spherical aberration (Z12) alone (P < .02); spherical aberration change was more prolate after CK. (4) After the CK monovision procedure, 80% of patients had J3 or better binocular UCVA at near; 84% of patients were satisfied. Satisfaction was associated with near UCVA of J3 or better in the monovision eye (P = .001) and subjectively good postoperative depth perception (P = .038).

Conclusions

CK seems to produce functional corneal multifocality with definable introduction of SIA and higher-order optical aberrations, and development of a more prolate corneal contour. These optical factors may militate toward improved near vision function.


Url:
PubMed: 17057812
PubMed Central: 1447583


Affiliations:


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<title>Purpose</title>
<p>To define the corneal optics of conductive keratoplasty (CK) and assess the clinical implications for hyperopia and presbyopia management.</p>
</sec>
<sec>
<title>Methods</title>
<p>Four analyses were done. (1) Multifocal effects: In a prospective study of CK, uncorrected visual acuity (UCVA) for a given refractive error in 72 postoperative eyes was compared to control eyes. (2) Surgically induced astigmatism (SIA): 203 eyes were analyzed for magnitude and axis of SIA. (3) Higher-order optical aberrations: Corneal higher-order optical aberrations were assessed for 36 eyes after CK and a similar patient population after hyperopic laser in situ keratomileusis (LASIK). (4) Presbyopia clinical trial: Visual acuity, refractive result, and patient questionnaires were analyzed for 150 subjects in a prospective, multicenter clinical trial of presbyopia management with CK.</p>
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<sec>
<title>Results</title>
<p>(1) 63% and 82% of eyes after CK had better UCVA at distance and near, respectively, than controls. (2) The mean SIA was 0.23 diopter (D) steepening at 175° (
<italic>P</italic>
< .001); mean magnitude was 0.66 D (SD, 0.43 D). (3) After CK, composite fourth- and sixth-order spherical aberration increased; change in (Z
<sup>12</sup>
) spherical aberration alone was not statistically significant. When compared to hyperopic LASIK, there was a statistically significant increase in composite fourth- and sixth-order spherical aberration (
<italic>P</italic>
< .01) and spherical aberration (Z
<sup>12</sup>
) alone (
<italic>P</italic>
< .02); spherical aberration change was more prolate after CK. (4) After the CK monovision procedure, 80% of patients had J3 or better binocular UCVA at near; 84% of patients were satisfied. Satisfaction was associated with near UCVA of J3 or better in the monovision eye (
<italic>P</italic>
= .001) and subjectively good postoperative depth perception (
<italic>P</italic>
= .038).</p>
</sec>
<sec>
<title>Conclusions</title>
<p>CK seems to produce functional corneal multifocality with definable introduction of SIA and higher-order optical aberrations, and development of a more prolate corneal contour. These optical factors may militate toward improved near vision function.</p>
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