Subconjunctival THC:YAG laser thermal sclerostomy.
Identifieur interne : 003812 ( Main/Curation ); précédent : 003811; suivant : 003813Subconjunctival THC:YAG laser thermal sclerostomy.
Auteurs : H D Hoskins [États-Unis] ; A G Iwach ; A. Vassiliadis ; M V Drake ; D R HenningsSource :
- Ophthalmology [ 0161-6420 ] ; 1991.
Descripteurs français
- KwdFr :
- MESH :
- traitement médicamenteux : Glaucome.
- usage thérapeutique : Fluorouracil.
- Adulte, Adulte d'âge moyen, Conjonctive, Enfant, Femelle, Glaucome, Humains, Mâle, Pression intraoculaire, Résultat thérapeutique, Sclérostomie, Sujet âgé, Sujet âgé de 80 ans ou plus, Thérapie laser, Études de suivi.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Fluorouracil.
- drug therapy : Glaucoma.
- surgery : Conjunctiva, Glaucoma.
- Adult, Aged, Aged, 80 and over, Child, Female, Follow-Up Studies, Humans, Intraocular Pressure, Laser Therapy, Male, Middle Aged, Sclerostomy, Treatment Outcome.
Abstract
A THC:YAG laser (thulium, holmium, chromium-doped YAG crystal) was used to create thermal sclerostomies in 21 glaucomatous eyes of 19 patients. The laser is a long-pulsed (300 microsec), compact, self-contained, solid state laser operating in the near infrared (2.1 mu). A 1-mm conjunctival stab incision was made 12 mm away from the sclerostomy site to allow entry of a specially designed 22-gauge (712 mu) optic probe that delivers energy at a right angle to the long axis of the fiber. Probe insertion produced minimal disturbance of the conjunctiva. Pulse energies of 80 mJ to 120 mJ were used with a repetition rate of 5 pulses/second. Total energy levels to produce full-thickness sclerostomies ranged from 1.4 to 4.8 J. Subconjunctival 5-fluorouracil injections were administered in 15 eyes. At 3 months the mean intraocular pressure of successful cases (16) was 14 mmHg (range, 9 to 22 mmHg). Of successful cases, the mean intraocular pressure at 6 months was 13 mmHg (range, 2 to 22 mmHg). Five cases failed within the initial 3 months, and 3 additional cases failed by 6 months. The authors conclude that this full-thickness sclerostomy technique may simplify filtering surgery without anterior chamber instrumentation and with minimal conjunctival trauma.
PubMed: 1945315
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pubmed:1945315Le document en format XML
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<author><name sortKey="Hoskins, H D" sort="Hoskins, H D" uniqKey="Hoskins H" first="H D" last="Hoskins">H D Hoskins</name>
<affiliation wicri:level="2"><nlm:affiliation>Foundation for Glaucoma Research, San Francisco, CA 94102.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
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<wicri:cityArea>Foundation for Glaucoma Research, San Francisco</wicri:cityArea>
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<author><name sortKey="Iwach, A G" sort="Iwach, A G" uniqKey="Iwach A" first="A G" last="Iwach">A G Iwach</name>
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<author><name sortKey="Vassiliadis, A" sort="Vassiliadis, A" uniqKey="Vassiliadis A" first="A" last="Vassiliadis">A. Vassiliadis</name>
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<author><name sortKey="Drake, M V" sort="Drake, M V" uniqKey="Drake M" first="M V" last="Drake">M V Drake</name>
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<author><name sortKey="Hennings, D R" sort="Hennings, D R" uniqKey="Hennings D" first="D R" last="Hennings">D R Hennings</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Subconjunctival THC:YAG laser thermal sclerostomy.</title>
<author><name sortKey="Hoskins, H D" sort="Hoskins, H D" uniqKey="Hoskins H" first="H D" last="Hoskins">H D Hoskins</name>
<affiliation wicri:level="2"><nlm:affiliation>Foundation for Glaucoma Research, San Francisco, CA 94102.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
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<author><name sortKey="Iwach, A G" sort="Iwach, A G" uniqKey="Iwach A" first="A G" last="Iwach">A G Iwach</name>
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<author><name sortKey="Vassiliadis, A" sort="Vassiliadis, A" uniqKey="Vassiliadis A" first="A" last="Vassiliadis">A. Vassiliadis</name>
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<author><name sortKey="Drake, M V" sort="Drake, M V" uniqKey="Drake M" first="M V" last="Drake">M V Drake</name>
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<author><name sortKey="Hennings, D R" sort="Hennings, D R" uniqKey="Hennings D" first="D R" last="Hennings">D R Hennings</name>
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<series><title level="j">Ophthalmology</title>
<idno type="ISSN">0161-6420</idno>
<imprint><date when="1991" type="published">1991</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Child</term>
<term>Conjunctiva (surgery)</term>
<term>Female</term>
<term>Fluorouracil (therapeutic use)</term>
<term>Follow-Up Studies</term>
<term>Glaucoma (drug therapy)</term>
<term>Glaucoma (surgery)</term>
<term>Humans</term>
<term>Intraocular Pressure</term>
<term>Laser Therapy</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sclerostomy</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Conjonctive ()</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Fluorouracil (usage thérapeutique)</term>
<term>Glaucome ()</term>
<term>Glaucome (traitement médicamenteux)</term>
<term>Humains</term>
<term>Mâle</term>
<term>Pression intraoculaire</term>
<term>Résultat thérapeutique</term>
<term>Sclérostomie</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Thérapie laser</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Fluorouracil</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Glaucoma</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Conjunctiva</term>
<term>Glaucoma</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Glaucome</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Fluorouracil</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Child</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Intraocular Pressure</term>
<term>Laser Therapy</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sclerostomy</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Conjonctive</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Glaucome</term>
<term>Humains</term>
<term>Mâle</term>
<term>Pression intraoculaire</term>
<term>Résultat thérapeutique</term>
<term>Sclérostomie</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Thérapie laser</term>
<term>Études de suivi</term>
</keywords>
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<front><div type="abstract" xml:lang="en">A THC:YAG laser (thulium, holmium, chromium-doped YAG crystal) was used to create thermal sclerostomies in 21 glaucomatous eyes of 19 patients. The laser is a long-pulsed (300 microsec), compact, self-contained, solid state laser operating in the near infrared (2.1 mu). A 1-mm conjunctival stab incision was made 12 mm away from the sclerostomy site to allow entry of a specially designed 22-gauge (712 mu) optic probe that delivers energy at a right angle to the long axis of the fiber. Probe insertion produced minimal disturbance of the conjunctiva. Pulse energies of 80 mJ to 120 mJ were used with a repetition rate of 5 pulses/second. Total energy levels to produce full-thickness sclerostomies ranged from 1.4 to 4.8 J. Subconjunctival 5-fluorouracil injections were administered in 15 eyes. At 3 months the mean intraocular pressure of successful cases (16) was 14 mmHg (range, 9 to 22 mmHg). Of successful cases, the mean intraocular pressure at 6 months was 13 mmHg (range, 2 to 22 mmHg). Five cases failed within the initial 3 months, and 3 additional cases failed by 6 months. The authors conclude that this full-thickness sclerostomy technique may simplify filtering surgery without anterior chamber instrumentation and with minimal conjunctival trauma.</div>
</front>
</TEI>
</record>
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