Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers
Identifieur interne : 002205 ( Istex/Corpus ); précédent : 002204; suivant : 002206Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers
Auteurs : Arielle N. B. KauvarSource :
- Lasers in Surgery and Medicine [ 0196-8092 ] ; 2012-02.
English descriptors
- KwdEn :
- Acad, Acad dermatol, Acad dermatol venereol, Adverse effects, Alexandrite laser, Alpha arbutin, Clearance, Clearance score, Combination treatment, Cosmet laser, Daily skin care regimen, Dermal, Dermatol, Dermatol surg, Erythema, Facial melasma, Fractional, Fractional photothermolysis, High incidence, Hydroquinone, Hyperpigmentation, Hypopigmentation, Laser, Laser treatment, Laser treatments, Lasers surg, Melanin, Melanin production, Melanocyte, Melanosomes, Melasma, Melasma clearance, Melasma recurrence, Microdermabrasion, Observational study, Percent clearance, Photothermolysis, Phototype, Pilot study, Refractory, Refractory melasma, Regimen, Selective photothermolysis, Side effects, Skin care, Skin care regimen, Skin rejuvenation, Skin type, Skin types, Spot size, Successful treatment, Surg, Treatment session, Treatment sessions, Uence, Uences.
- Teeft :
- Acad, Acad dermatol, Acad dermatol venereol, Adverse effects, Alexandrite laser, Alpha arbutin, Clearance, Clearance score, Combination treatment, Cosmet laser, Daily skin care regimen, Dermal, Dermatol, Dermatol surg, Erythema, Facial melasma, Fractional, Fractional photothermolysis, High incidence, Hydroquinone, Hyperpigmentation, Hypopigmentation, Laser, Laser treatment, Laser treatments, Lasers surg, Melanin, Melanin production, Melanocyte, Melanosomes, Melasma, Melasma clearance, Melasma recurrence, Microdermabrasion, Observational study, Percent clearance, Photothermolysis, Phototype, Pilot study, Refractory, Refractory melasma, Regimen, Selective photothermolysis, Side effects, Skin care, Skin care regimen, Skin rejuvenation, Skin type, Skin types, Spot size, Successful treatment, Surg, Treatment session, Treatment sessions, Uence, Uences.
Abstract
A common, disfiguring problem in women, melasma is often refractory to treatment, and long‐term remissions are difficult to achieve. This study assessed the safety and effectiveness of a procedure combining microdermabrasion, a topical regimen, and low fluence Q‐switched Nd:YAG laser treatment.
Url:
DOI: 10.1002/lsm.21156
Links to Exploration step
ISTEX:9948CE989C147271921DF2F3D75A6ACAE7D89E66Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers</title><author><name sortKey="Kauvar, Arielle N B" sort="Kauvar, Arielle N B" uniqKey="Kauvar A" first="Arielle N. B." last="Kauvar">Arielle N. B. Kauvar</name><affiliation><mods:affiliation>New York Laser & Skin Care, New York, NY 10028</mods:affiliation></affiliation><affiliation><mods:affiliation>Clinical Professor of Dermatology, NYU School of Medicine, New York, NY 10016</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: info@nylaserskincare.com</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: New York Laser & Skin Care, 1044 Fifth Avenue, New York, NY 10028.</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:9948CE989C147271921DF2F3D75A6ACAE7D89E66</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/lsm.21156</idno><idno type="url">https://api.istex.fr/document/9948CE989C147271921DF2F3D75A6ACAE7D89E66/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002205</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002205</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers<ref type="note" target="#fn1"></ref></title><author><name sortKey="Kauvar, Arielle N B" sort="Kauvar, Arielle N B" uniqKey="Kauvar A" first="Arielle N. B." last="Kauvar">Arielle N. B. Kauvar</name><affiliation><mods:affiliation>New York Laser & Skin Care, New York, NY 10028</mods:affiliation></affiliation><affiliation><mods:affiliation>Clinical Professor of Dermatology, NYU School of Medicine, New York, NY 10016</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: info@nylaserskincare.com</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: New York Laser & Skin Care, 1044 Fifth Avenue, New York, NY 10028.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Lasers in Surgery and Medicine</title><title level="j" type="alt">LASERS IN SURGERY AND MEDICINE</title><idno type="ISSN">0196-8092</idno><idno type="eISSN">1096-9101</idno><imprint><biblScope unit="vol">44</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="117">117</biblScope><biblScope unit="page" to="124">124</biblScope><biblScope unit="page-count">8</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-02">2012-02</date></imprint><idno type="ISSN">0196-8092</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0196-8092</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acad</term><term>Acad dermatol</term><term>Acad dermatol venereol</term><term>Adverse effects</term><term>Alexandrite laser</term><term>Alpha arbutin</term><term>Clearance</term><term>Clearance score</term><term>Combination treatment</term><term>Cosmet laser</term><term>Daily skin care regimen</term><term>Dermal</term><term>Dermatol</term><term>Dermatol surg</term><term>Erythema</term><term>Facial melasma</term><term>Fractional</term><term>Fractional photothermolysis</term><term>High incidence</term><term>Hydroquinone</term><term>Hyperpigmentation</term><term>Hypopigmentation</term><term>Laser</term><term>Laser treatment</term><term>Laser treatments</term><term>Lasers surg</term><term>Melanin</term><term>Melanin production</term><term>Melanocyte</term><term>Melanosomes</term><term>Melasma</term><term>Melasma clearance</term><term>Melasma recurrence</term><term>Microdermabrasion</term><term>Observational study</term><term>Percent clearance</term><term>Photothermolysis</term><term>Phototype</term><term>Pilot study</term><term>Refractory</term><term>Refractory melasma</term><term>Regimen</term><term>Selective photothermolysis</term><term>Side effects</term><term>Skin care</term><term>Skin care regimen</term><term>Skin rejuvenation</term><term>Skin type</term><term>Skin types</term><term>Spot size</term><term>Successful treatment</term><term>Surg</term><term>Treatment session</term><term>Treatment sessions</term><term>Uence</term><term>Uences</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Acad</term><term>Acad dermatol</term><term>Acad dermatol venereol</term><term>Adverse effects</term><term>Alexandrite laser</term><term>Alpha arbutin</term><term>Clearance</term><term>Clearance score</term><term>Combination treatment</term><term>Cosmet laser</term><term>Daily skin care regimen</term><term>Dermal</term><term>Dermatol</term><term>Dermatol surg</term><term>Erythema</term><term>Facial melasma</term><term>Fractional</term><term>Fractional photothermolysis</term><term>High incidence</term><term>Hydroquinone</term><term>Hyperpigmentation</term><term>Hypopigmentation</term><term>Laser</term><term>Laser treatment</term><term>Laser treatments</term><term>Lasers surg</term><term>Melanin</term><term>Melanin production</term><term>Melanocyte</term><term>Melanosomes</term><term>Melasma</term><term>Melasma clearance</term><term>Melasma recurrence</term><term>Microdermabrasion</term><term>Observational study</term><term>Percent clearance</term><term>Photothermolysis</term><term>Phototype</term><term>Pilot study</term><term>Refractory</term><term>Refractory melasma</term><term>Regimen</term><term>Selective photothermolysis</term><term>Side effects</term><term>Skin care</term><term>Skin care regimen</term><term>Skin rejuvenation</term><term>Skin type</term><term>Skin types</term><term>Spot size</term><term>Successful treatment</term><term>Surg</term><term>Treatment session</term><term>Treatment sessions</term><term>Uence</term><term>Uences</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">A common, disfiguring problem in women, melasma is often refractory to treatment, and long‐term remissions are difficult to achieve. This study assessed the safety and effectiveness of a procedure combining microdermabrasion, a topical regimen, and low fluence Q‐switched Nd:YAG laser treatment.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>laser</json:string><json:string>melasma</json:string><json:string>dermatol</json:string><json:string>surg</json:string><json:string>laser treatment</json:string><json:string>microdermabrasion</json:string><json:string>hyperpigmentation</json:string><json:string>uence</json:string><json:string>melanocyte</json:string><json:string>melanin</json:string><json:string>photothermolysis</json:string><json:string>uences</json:string><json:string>dermatol surg</json:string><json:string>hydroquinone</json:string><json:string>melanosomes</json:string><json:string>skin care regimen</json:string><json:string>regimen</json:string><json:string>acad</json:string><json:string>phototype</json:string><json:string>skin type</json:string><json:string>erythema</json:string><json:string>dermal</json:string><json:string>treatment sessions</json:string><json:string>hypopigmentation</json:string><json:string>percent clearance</json:string><json:string>lasers surg</json:string><json:string>laser treatments</json:string><json:string>adverse effects</json:string><json:string>fractional photothermolysis</json:string><json:string>acad dermatol</json:string><json:string>selective photothermolysis</json:string><json:string>refractory melasma</json:string><json:string>spot size</json:string><json:string>fractional</json:string><json:string>clearance</json:string><json:string>melasma recurrence</json:string><json:string>skin types</json:string><json:string>refractory</json:string><json:string>combination treatment</json:string><json:string>side effects</json:string><json:string>high incidence</json:string><json:string>daily skin care regimen</json:string><json:string>skin rejuvenation</json:string><json:string>melasma clearance</json:string><json:string>clearance score</json:string><json:string>alpha arbutin</json:string><json:string>melanin production</json:string><json:string>treatment session</json:string><json:string>observational study</json:string><json:string>cosmet laser</json:string><json:string>facial melasma</json:string><json:string>acad dermatol venereol</json:string><json:string>skin care</json:string><json:string>alexandrite laser</json:string><json:string>pilot study</json:string><json:string>successful treatment</json:string></teeft></keywords><author><json:item><name>Arielle N.B. Kauvar MD</name><affiliations><json:string>New York Laser & Skin Care, New York, NY 10028</json:string><json:string>Clinical Professor of Dermatology, NYU School of Medicine, New York, NY 10016</json:string><json:string>New York Laser & Skin Care, 1044 Fifth Avenue, New York, NY 10028.</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>chloasma</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>pigment</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>melanosome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Nd:YAG laser</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>hyperpigmentation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>phototypes</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>mixed‐type melasma</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>low‐fluence laser</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>microdermabrasion</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>melanin</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>melanocytes</value></json:item></subject><articleId><json:string>LSM21156</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>caseStudy</json:string></originalGenre><qualityIndicators><score>5.352</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>295</abstractCharCount><pdfWordCount>4860</pdfWordCount><pdfCharCount>31102</pdfCharCount><pdfPageCount>8</pdfPageCount><abstractWordCount>41</abstractWordCount></qualityIndicators><title>Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers</title><genre><json:string>case-report</json:string></genre><host><title>Lasers in Surgery and Medicine</title><language><json:string>unknown</json:string></language><doi><json:string>10.1002/(ISSN)1096-9101</json:string></doi><issn><json:string>0196-8092</json:string></issn><eissn><json:string>1096-9101</json:string></eissn><publisherId><json:string>LSM</json:string></publisherId><volume>44</volume><issue>2</issue><pages><first>117</first><last>124</last><total>8</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Clinical Report</value></json:item></subject></host><categories><wos><json:string>science</json:string><json:string>surgery</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>dermatology & venereal diseases</json:string></scienceMetrix></categories><publicationDate>2012</publicationDate><copyrightDate>2012</copyrightDate><doi><json:string>10.1002/lsm.21156</json:string></doi><id>9948CE989C147271921DF2F3D75A6ACAE7D89E66</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/9948CE989C147271921DF2F3D75A6ACAE7D89E66/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/9948CE989C147271921DF2F3D75A6ACAE7D89E66/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/9948CE989C147271921DF2F3D75A6ACAE7D89E66/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers<ref type="note" target="#fn1"></ref></title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><licence>Copyright © 2011 Wiley Periodicals, Inc.</licence></availability><date type="published" when="2012-02"></date></publicationStmt><notesStmt><note type="content-type" subtype="case-report" source="caseStudy" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-29919SZJ-6">case-report</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="case-report"><analytic><title level="a" type="main" xml:lang="en">Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers<ref type="note" target="#fn1"></ref></title><title level="a" type="short" xml:lang="en">SUCCESSFUL TREATMENT OF MELASMA</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">Arielle N.B.</forename><surname>Kauvar</surname><roleName type="degree">MD</roleName></persName><email>info@nylaserskincare.com</email><affiliation>New York Laser & Skin Care, New York, NY 10028<address><country key="US"></country></address></affiliation><affiliation>Clinical Professor of Dermatology, NYU School of Medicine, New York, NY 10016<address><country key="US"></country></address></affiliation><affiliation>New York Laser & Skin Care, 1044 Fifth Avenue, New York, NY 10028.</affiliation></author><idno type="istex">9948CE989C147271921DF2F3D75A6ACAE7D89E66</idno><idno type="ark">ark:/67375/WNG-BMKZRV9S-3</idno><idno type="DOI">10.1002/lsm.21156</idno><idno type="unit">LSM21156</idno><idno type="toTypesetVersion">file:LSM.LSM21156.pdf</idno></analytic><monogr><title level="j" type="main">Lasers in Surgery and Medicine</title><title level="j" type="alt">LASERS IN SURGERY AND MEDICINE</title><idno type="pISSN">0196-8092</idno><idno type="eISSN">1096-9101</idno><idno type="book-DOI">10.1002/(ISSN)1096-9101</idno><idno type="book-part-DOI">10.1002/lsm.v44.2</idno><idno type="product">LSM</idno><imprint><biblScope unit="vol">44</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="117">117</biblScope><biblScope unit="page" to="124">124</biblScope><biblScope unit="page-count">8</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-02"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head>
Background and Objective
<p>A common, disfiguring problem in women, melasma is often refractory to treatment, and long‐term remissions are difficult to achieve. This study assessed the safety and effectiveness of a procedure combining microdermabrasion, a topical regimen, and low fluence Q‐switched Nd:YAG laser treatment.</p>
Materials and Methods
<p>In this observational study of 27 female subjects, phototypes II–V, referred for treatment of mixed‐type melasma refractory to previous therapies, low‐fluence QS Nd:YAG laser treatment of 1.6–2 J/cm<hi rend="superscript">2</hi> with 5 or 6 mm spot was administered immediately following microdermabrasion. Daily application of a broad‐spectrum sunscreen began immediately; subjects used a topical skin care regimen of hydroquinone with tretinoin or vitamin C. Treatments were repeated at 4‐week intervals. Follow‐up assessment was done 3–12 months after the last treatment. Adverse effects were recorded at each visit. Standardized digital photographs obtained before each treatment session and at follow‐up visits were objectively assessed by blinded comparison using a quartile grading system.</p>
Results
<p>Treatment was successful in all skin types, deemed painless by all subjects, and required no anesthesia. Average number of treatments was 2.6. Twenty‐two subjects (81%) had >75% clearance of melasma; 11 subjects (40%) achieved >95% clearance. Most subjects showed >50% clearance of their melasma 1 month after the first treatment. Side effects were limited to mild post‐treatment erythema, which developed after the microdermabrasion and lasted approximately 30–60 minutes. Four subjects noted temporary exacerbation of melasma after inadvertent sun exposure, but this resolved within several weeks of resuming the topical skin care regime. Remission lasted at least 6 months.</p>
Conclusion
<p>Microdermabrasion plus low‐fluence QS Nd:YAG laser treatment is a simple, non‐invasive procedure with minimal risk, no recovery time, and long‐lasting remission. Treatment works on all skin phototypes in just two to three treatment sessions. Subject compliance with skin care was excellent, probably due to the dramatic improvement observed within 4 weeks. Lasers Surg. Med. 44:117–124, 2012. © 2012 Wiley Periodicals, Inc.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="kwd1">chloasma</term><term xml:id="kwd2">pigment</term><term xml:id="kwd3">melanosome</term><term xml:id="kwd4">Nd:YAG laser</term><term xml:id="kwd5">hyperpigmentation</term><term xml:id="kwd6">phototypes</term><term xml:id="kwd7">mixed‐type melasma</term><term xml:id="kwd8">low‐fluence laser</term><term xml:id="kwd9">microdermabrasion</term><term xml:id="kwd10">melanin</term><term xml:id="kwd11">melanocytes</term></keywords><keywords rend="articleCategory"><term>Clinical Report</term></keywords><keywords rend="tocHeading1"><term>Clinical Reports</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/9948CE989C147271921DF2F3D75A6ACAE7D89E66/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1096-9101</doi><issn type="print">0196-8092</issn><issn type="electronic">1096-9101</issn><idGroup><id type="product" value="LSM"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="LASERS IN SURGERY AND MEDICINE">Lasers in Surgery and Medicine</title><title type="short">Lasers Surg. Med.</title></titleGroup></publicationMeta><publicationMeta level="part" position="20"><doi origin="wiley" registered="yes">10.1002/lsm.v44.2</doi><numberingGroup><numbering type="journalVolume" number="44">44</numbering><numbering type="journalIssue">2</numbering></numberingGroup><coverDate startDate="2012-02">February 2012</coverDate></publicationMeta><publicationMeta level="unit" type="caseStudy" position="60" status="forIssue"><doi origin="wiley" registered="yes">10.1002/lsm.21156</doi><idGroup><id type="unit" value="LSM21156"></id></idGroup><countGroup><count type="pageTotal" number="8"></count></countGroup><titleGroup><title type="articleCategory">Clinical Report</title><title type="tocHeading1">Clinical Reports</title></titleGroup><copyright ownership="publisher">Copyright © 2011 Wiley Periodicals, Inc.</copyright><eventGroup><event type="manuscriptAccepted" date="2011-11-23"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:3.1.2.1 standalone mode:FullText" date="2012-02-14"></event><event type="publishedOnlineEarlyUnpaginated" date="2012-01-03"></event><event type="publishedOnlineFinalForm" date="2012-02-14"></event><event type="firstOnline" date="2012-01-03"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-01"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.3.4 mode:FullText" date="2015-02-24"></event></eventGroup><numberingGroup><numbering type="pageFirst">117</numbering><numbering type="pageLast">124</numbering></numberingGroup><correspondenceTo>New York Laser & Skin Care, 1044 Fifth Avenue, New York, NY 10028.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:LSM.LSM21156.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="7"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="48"></count><count type="wordTotal" number="5581"></count></countGroup><titleGroup><title type="main" xml:lang="en">Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers<link href="#fn1"></link></title><title type="short" xml:lang="en">SUCCESSFUL TREATMENT OF MELASMA</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1 #af2" corresponding="yes"><personName><givenNames>Arielle N.B.</givenNames><familyName>Kauvar</familyName><degrees>MD</degrees></personName><contactDetails><email>info@nylaserskincare.com</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="US" type="organization"><unparsedAffiliation>New York Laser & Skin Care, New York, NY 10028</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="US" type="organization"><unparsedAffiliation>Clinical Professor of Dermatology, NYU School of Medicine, New York, NY 10016</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">chloasma</keyword><keyword xml:id="kwd2">pigment</keyword><keyword xml:id="kwd3">melanosome</keyword><keyword xml:id="kwd4">Nd:YAG laser</keyword><keyword xml:id="kwd5">hyperpigmentation</keyword><keyword xml:id="kwd6">phototypes</keyword><keyword xml:id="kwd7">mixed‐type melasma</keyword><keyword xml:id="kwd8">low‐fluence laser</keyword><keyword xml:id="kwd9">microdermabrasion</keyword><keyword xml:id="kwd10">melanin</keyword><keyword xml:id="kwd11">melanocytes</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><section xml:id="abs1-1"><title type="main">Background and Objective</title><p>A common, disfiguring problem in women, melasma is often refractory to treatment, and long‐term remissions are difficult to achieve. This study assessed the safety and effectiveness of a procedure combining microdermabrasion, a topical regimen, and low fluence Q‐switched Nd:YAG laser treatment.</p></section><section xml:id="abs1-2"><title type="main">Materials and Methods</title><p>In this observational study of 27 female subjects, phototypes II–V, referred for treatment of mixed‐type melasma refractory to previous therapies, low‐fluence QS Nd:YAG laser treatment of 1.6–2 J/cm<sup>2</sup> with 5 or 6 mm spot was administered immediately following microdermabrasion. Daily application of a broad‐spectrum sunscreen began immediately; subjects used a topical skin care regimen of hydroquinone with tretinoin or vitamin C. Treatments were repeated at 4‐week intervals. Follow‐up assessment was done 3–12 months after the last treatment. Adverse effects were recorded at each visit. Standardized digital photographs obtained before each treatment session and at follow‐up visits were objectively assessed by blinded comparison using a quartile grading system.</p></section><section xml:id="abs1-3"><title type="main">Results</title><p>Treatment was successful in all skin types, deemed painless by all subjects, and required no anesthesia. Average number of treatments was 2.6. Twenty‐two subjects (81%) had >75% clearance of melasma; 11 subjects (40%) achieved >95% clearance. Most subjects showed >50% clearance of their melasma 1 month after the first treatment. Side effects were limited to mild post‐treatment erythema, which developed after the microdermabrasion and lasted approximately 30–60 minutes. Four subjects noted temporary exacerbation of melasma after inadvertent sun exposure, but this resolved within several weeks of resuming the topical skin care regime. Remission lasted at least 6 months.</p></section><section xml:id="abs1-4"><title type="main">Conclusion</title><p>Microdermabrasion plus low‐fluence QS Nd:YAG laser treatment is a simple, non‐invasive procedure with minimal risk, no recovery time, and long‐lasting remission. Treatment works on all skin phototypes in just two to three treatment sessions. Subject compliance with skin care was excellent, probably due to the dramatic improvement observed within 4 weeks. Lasers Surg. Med. 44:117–124, 2012. © 2012 Wiley Periodicals, Inc.</p></section></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Conflict of interest: None.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>SUCCESSFUL TREATMENT OF MELASMA</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers</title></titleInfo><name type="personal"><namePart type="given">Arielle N.B.</namePart><namePart type="family">Kauvar</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>New York Laser & Skin Care, New York, NY 10028</affiliation><affiliation>Clinical Professor of Dermatology, NYU School of Medicine, New York, NY 10016</affiliation><affiliation>E-mail: info@nylaserskincare.com</affiliation><affiliation>Correspondence address: New York Laser & Skin Care, 1044 Fifth Avenue, New York, NY 10028.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="case-report" displayLabel="caseStudy" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-29919SZJ-6">case-report</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2012-02</dateIssued><dateValid encoding="w3cdtf">2011-11-23</dateValid><copyrightDate encoding="w3cdtf">2012</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">7</extent><extent unit="tables">1</extent><extent unit="references">48</extent><extent unit="words">5581</extent></physicalDescription><abstract>A common, disfiguring problem in women, melasma is often refractory to treatment, and long‐term remissions are difficult to achieve. This study assessed the safety and effectiveness of a procedure combining microdermabrasion, a topical regimen, and low fluence Q‐switched Nd:YAG laser treatment.</abstract><abstract>In this observational study of 27 female subjects, phototypes II–V, referred for treatment of mixed‐type melasma refractory to previous therapies, low‐fluence QS Nd:YAG laser treatment of 1.6–2 J/cm2 with 5 or 6 mm spot was administered immediately following microdermabrasion. Daily application of a broad‐spectrum sunscreen began immediately; subjects used a topical skin care regimen of hydroquinone with tretinoin or vitamin C. Treatments were repeated at 4‐week intervals. Follow‐up assessment was done 3–12 months after the last treatment. Adverse effects were recorded at each visit. Standardized digital photographs obtained before each treatment session and at follow‐up visits were objectively assessed by blinded comparison using a quartile grading system.</abstract><abstract>Treatment was successful in all skin types, deemed painless by all subjects, and required no anesthesia. Average number of treatments was 2.6. Twenty‐two subjects (81%) had >75% clearance of melasma; 11 subjects (40%) achieved >95% clearance. Most subjects showed >50% clearance of their melasma 1 month after the first treatment. Side effects were limited to mild post‐treatment erythema, which developed after the microdermabrasion and lasted approximately 30–60 minutes. Four subjects noted temporary exacerbation of melasma after inadvertent sun exposure, but this resolved within several weeks of resuming the topical skin care regime. Remission lasted at least 6 months.</abstract><abstract>Microdermabrasion plus low‐fluence QS Nd:YAG laser treatment is a simple, non‐invasive procedure with minimal risk, no recovery time, and long‐lasting remission. Treatment works on all skin phototypes in just two to three treatment sessions. Subject compliance with skin care was excellent, probably due to the dramatic improvement observed within 4 weeks. Lasers Surg. Med. 44:117–124, 2012. © 2012 Wiley Periodicals, Inc.</abstract><note type="content">*Conflict of interest: None.</note><subject lang="en"><genre>keywords</genre><topic>chloasma</topic><topic>pigment</topic><topic>melanosome</topic><topic>Nd:YAG laser</topic><topic>hyperpigmentation</topic><topic>phototypes</topic><topic>mixed‐type melasma</topic><topic>low‐fluence laser</topic><topic>microdermabrasion</topic><topic>melanin</topic><topic>melanocytes</topic></subject><relatedItem type="host"><titleInfo><title>Lasers in Surgery and Medicine</title></titleInfo><titleInfo type="abbreviated"><title>Lasers Surg. Med.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Clinical Report</topic></subject><identifier type="ISSN">0196-8092</identifier><identifier type="eISSN">1096-9101</identifier><identifier type="DOI">10.1002/(ISSN)1096-9101</identifier><identifier type="PublisherID">LSM</identifier><part><date>2012</date><detail type="volume"><caption>vol.</caption><number>44</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>117</start><end>124</end><total>8</total></extent></part></relatedItem><identifier type="istex">9948CE989C147271921DF2F3D75A6ACAE7D89E66</identifier><identifier type="ark">ark:/67375/WNG-BMKZRV9S-3</identifier><identifier type="DOI">10.1002/lsm.21156</identifier><identifier type="ArticleID">LSM21156</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2011 Wiley Periodicals, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/9948CE989C147271921DF2F3D75A6ACAE7D89E66/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/ThuliumV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002205 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 002205 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Terre
|area= ThuliumV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:9948CE989C147271921DF2F3D75A6ACAE7D89E66
|texte= Successful treatment of melasma using a combination of microdermabrasion and Q‐switched Nd:YAG lasers
}}
| This area was generated with Dilib version V0.6.21. |  |