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Two-level antibacterial coating with both release-killing and contact-killing capabilities.

Identifieur interne : 000C04 ( Main/Corpus ); précédent : 000C03; suivant : 000C05

Two-level antibacterial coating with both release-killing and contact-killing capabilities.

Auteurs : Zhi Li ; Daeyeon Lee ; Xiaoxia Sheng ; Robert E. Cohen ; Michael F. Rubner

Source :

RBID : pubmed:17106967

English descriptors

Abstract

Using a combination of an aqueous layer-by-layer deposition technique, nanoparticle surface modification chemistry, and nanoreactor chemistry, we constructed thin film coatings with two distinct layered functional regions: a reservoir for the loading and release of bactericidal chemicals and a nanoparticle surface cap with immobilized bactericides. This results in dual-functional bactericidal coatings bearing both chemical-releasing bacteria-killing capacity and contact bacteria-killing capacity. These dual-functional coatings showed very high initial bacteria-killing efficiency due to the release of Ag ions and retained significant antibacterial activity after the depletion of embedded Ag because of the immobilized quaternary ammonium salts.

DOI: 10.1021/la0622166
PubMed: 17106967

Links to Exploration step

pubmed:17106967

Le document en format XML

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<name sortKey="Lee, Daeyeon" sort="Lee, Daeyeon" uniqKey="Lee D" first="Daeyeon" last="Lee">Daeyeon Lee</name>
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<name sortKey="Sheng, Xiaoxia" sort="Sheng, Xiaoxia" uniqKey="Sheng X" first="Xiaoxia" last="Sheng">Xiaoxia Sheng</name>
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<div type="abstract" xml:lang="en">Using a combination of an aqueous layer-by-layer deposition technique, nanoparticle surface modification chemistry, and nanoreactor chemistry, we constructed thin film coatings with two distinct layered functional regions: a reservoir for the loading and release of bactericidal chemicals and a nanoparticle surface cap with immobilized bactericides. This results in dual-functional bactericidal coatings bearing both chemical-releasing bacteria-killing capacity and contact bacteria-killing capacity. These dual-functional coatings showed very high initial bacteria-killing efficiency due to the release of Ag ions and retained significant antibacterial activity after the depletion of embedded Ag because of the immobilized quaternary ammonium salts.</div>
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