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Bactericidal mechanism of Ag/Al2O3 against Escherichia coli.

Identifieur interne : 000B85 ( Main/Corpus ); précédent : 000B84; suivant : 000B86

Bactericidal mechanism of Ag/Al2O3 against Escherichia coli.

Auteurs : Qingyun Chang ; Lizhu Yan ; Meixue Chen ; Hong He ; Jiuhui Qu

Source :

RBID : pubmed:17902710

English descriptors

Abstract

The bactericidal process of Ag/Al2O3 to Escherichia coli has been investigated to clarify the bactericidal mechanism. In SEM images, the configuration of E. coli cells contacting with the catalyst surface was quite different from that contacting with AgNO3 solution, which indicated that the Ag+ eluted from the catalyst did not play an important role in the bactericidal process. The bactericidal experiments strongly confirmed the contribution of multiform reactive oxygen species (ROS) (super oxide dismutase (SOD) and catalase as the scavengers for O2*- and H2O2, respectively) to bactericidal effect on the catalyst surface. Furthermore, the surface modification of Ag/Al2O3 by ultraviolet and formaldehyde influenced the bactericidal effect obviously, which not only confirmed the bactericidal mechanism of catalytic oxidation but also provided evidence for the synergistic effect between Ag and Al2O3 on the catalyst surface.

DOI: 10.1021/la701006r
PubMed: 17902710

Links to Exploration step

pubmed:17902710

Le document en format XML

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<name sortKey="Chang, Qingyun" sort="Chang, Qingyun" uniqKey="Chang Q" first="Qingyun" last="Chang">Qingyun Chang</name>
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<nlm:affiliation>Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.</nlm:affiliation>
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<name sortKey="Yan, Lizhu" sort="Yan, Lizhu" uniqKey="Yan L" first="Lizhu" last="Yan">Lizhu Yan</name>
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<name sortKey="Chen, Meixue" sort="Chen, Meixue" uniqKey="Chen M" first="Meixue" last="Chen">Meixue Chen</name>
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<name sortKey="He, Hong" sort="He, Hong" uniqKey="He H" first="Hong" last="He">Hong He</name>
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<name sortKey="Qu, Jiuhui" sort="Qu, Jiuhui" uniqKey="Qu J" first="Jiuhui" last="Qu">Jiuhui Qu</name>
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<name sortKey="Chang, Qingyun" sort="Chang, Qingyun" uniqKey="Chang Q" first="Qingyun" last="Chang">Qingyun Chang</name>
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<term>Catalase (pharmacology)</term>
<term>Escherichia coli (drug effects)</term>
<term>Escherichia coli (metabolism)</term>
<term>Escherichia coli (ultrastructure)</term>
<term>Formaldehyde (MeSH)</term>
<term>Free Radical Scavengers (pharmacology)</term>
<term>Microscopy, Electron, Scanning (MeSH)</term>
<term>Reactive Oxygen Species (metabolism)</term>
<term>Silver (pharmacology)</term>
<term>Superoxide Dismutase (pharmacology)</term>
<term>Surface Properties (MeSH)</term>
<term>Ultraviolet Rays (MeSH)</term>
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<term>Formaldehyde</term>
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<div type="abstract" xml:lang="en">The bactericidal process of Ag/Al2O3 to Escherichia coli has been investigated to clarify the bactericidal mechanism. In SEM images, the configuration of E. coli cells contacting with the catalyst surface was quite different from that contacting with AgNO3 solution, which indicated that the Ag+ eluted from the catalyst did not play an important role in the bactericidal process. The bactericidal experiments strongly confirmed the contribution of multiform reactive oxygen species (ROS) (super oxide dismutase (SOD) and catalase as the scavengers for O2*- and H2O2, respectively) to bactericidal effect on the catalyst surface. Furthermore, the surface modification of Ag/Al2O3 by ultraviolet and formaldehyde influenced the bactericidal effect obviously, which not only confirmed the bactericidal mechanism of catalytic oxidation but also provided evidence for the synergistic effect between Ag and Al2O3 on the catalyst surface.</div>
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<AbstractText>The bactericidal process of Ag/Al2O3 to Escherichia coli has been investigated to clarify the bactericidal mechanism. In SEM images, the configuration of E. coli cells contacting with the catalyst surface was quite different from that contacting with AgNO3 solution, which indicated that the Ag+ eluted from the catalyst did not play an important role in the bactericidal process. The bactericidal experiments strongly confirmed the contribution of multiform reactive oxygen species (ROS) (super oxide dismutase (SOD) and catalase as the scavengers for O2*- and H2O2, respectively) to bactericidal effect on the catalyst surface. Furthermore, the surface modification of Ag/Al2O3 by ultraviolet and formaldehyde influenced the bactericidal effect obviously, which not only confirmed the bactericidal mechanism of catalytic oxidation but also provided evidence for the synergistic effect between Ag and Al2O3 on the catalyst surface.</AbstractText>
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