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A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating.

Identifieur interne : 000B82 ( Main/Corpus ); précédent : 000B81; suivant : 000B83

A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating.

Auteurs : Weiyong Yuan ; Jian Ji ; Jinhong Fu ; Jiacong Shen

Source :

RBID : pubmed:18098202

English descriptors

Abstract

A multifunctional multilayered film containing TiO(2) nanoparticles as contact-active antibacterial agent and nanosilver as a release-active antibacterial agent was fabricated via layer-by-layer assembly. TiO(2) nanoparticles with the anatase crystalline dominant structure were synthesized via a sol-gel method. The QCM, AFM, and contact angle measurement results indicated that the TiO(2) nanoparticle-chitosan was successfully assembled with heparin via layer-by-layer assembly. The UV visible spectroscopy demonstrated that the silver ions could be loaded into the multilayers and in situ synthesize silver nanoparticles in the multilayers template. The short-term antibacterial assay showed the TiO(2)-chitosan/heparin multilayers loaded with nanosilver was bactericidal both in the low intensity UV light and in the dark. The long-term antibacterial assay indicated although the antibacterial in dark decreased with the PBS immersion time, the hybrid multilayered films sustained the long-term antibacterial in the low intensity UV light.

DOI: 10.1002/jbm.b.30979
PubMed: 18098202

Links to Exploration step

pubmed:18098202

Le document en format XML

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<div type="abstract" xml:lang="en">A multifunctional multilayered film containing TiO(2) nanoparticles as contact-active antibacterial agent and nanosilver as a release-active antibacterial agent was fabricated via layer-by-layer assembly. TiO(2) nanoparticles with the anatase crystalline dominant structure were synthesized via a sol-gel method. The QCM, AFM, and contact angle measurement results indicated that the TiO(2) nanoparticle-chitosan was successfully assembled with heparin via layer-by-layer assembly. The UV visible spectroscopy demonstrated that the silver ions could be loaded into the multilayers and in situ synthesize silver nanoparticles in the multilayers template. The short-term antibacterial assay showed the TiO(2)-chitosan/heparin multilayers loaded with nanosilver was bactericidal both in the low intensity UV light and in the dark. The long-term antibacterial assay indicated although the antibacterial in dark decreased with the PBS immersion time, the hybrid multilayered films sustained the long-term antibacterial in the low intensity UV light.</div>
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