A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating.
Identifieur interne : 000B82 ( Main/Corpus ); précédent : 000B81; suivant : 000B83A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating.
Auteurs : Weiyong Yuan ; Jian Ji ; Jinhong Fu ; Jiacong ShenSource :
- Journal of biomedical materials research. Part B, Applied biomaterials [ 1552-4981 ] ; 2008.
English descriptors
- KwdEn :
- Anti-Bacterial Agents (chemistry), Chitosan (chemistry), Escherichia coli (growth & development), Membranes, Artificial (MeSH), Microbial Sensitivity Tests (methods), Nanoparticles (chemistry), Photochemistry (MeSH), Photosensitizing Agents (chemistry), Silver (chemistry), Time Factors (MeSH), Titanium (chemistry), Ultraviolet Rays (MeSH).
- MESH :
- chemical , chemistry : Anti-Bacterial Agents, Chitosan, Photosensitizing Agents, Silver, Titanium.
- chemistry : Nanoparticles.
- growth & development : Escherichia coli.
- methods : Microbial Sensitivity Tests.
- chemical : Membranes, Artificial, Photochemistry, Time Factors, Ultraviolet Rays.
Abstract
A multifunctional multilayered film containing TiO(2) nanoparticles as contact-active antibacterial agent and nanosilver as a release-active antibacterial agent was fabricated via layer-by-layer assembly. TiO(2) nanoparticles with the anatase crystalline dominant structure were synthesized via a sol-gel method. The QCM, AFM, and contact angle measurement results indicated that the TiO(2) nanoparticle-chitosan was successfully assembled with heparin via layer-by-layer assembly. The UV visible spectroscopy demonstrated that the silver ions could be loaded into the multilayers and in situ synthesize silver nanoparticles in the multilayers template. The short-term antibacterial assay showed the TiO(2)-chitosan/heparin multilayers loaded with nanosilver was bactericidal both in the low intensity UV light and in the dark. The long-term antibacterial assay indicated although the antibacterial in dark decreased with the PBS immersion time, the hybrid multilayered films sustained the long-term antibacterial in the low intensity UV light.
DOI: 10.1002/jbm.b.30979
PubMed: 18098202
Links to Exploration step
pubmed:18098202Le document en format XML
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<author><name sortKey="Yuan, Weiyong" sort="Yuan, Weiyong" uniqKey="Yuan W" first="Weiyong" last="Yuan">Weiyong Yuan</name>
<affiliation><nlm:affiliation>Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, People's Republic of China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Ji, Jian" sort="Ji, Jian" uniqKey="Ji J" first="Jian" last="Ji">Jian Ji</name>
</author>
<author><name sortKey="Fu, Jinhong" sort="Fu, Jinhong" uniqKey="Fu J" first="Jinhong" last="Fu">Jinhong Fu</name>
</author>
<author><name sortKey="Shen, Jiacong" sort="Shen, Jiacong" uniqKey="Shen J" first="Jiacong" last="Shen">Jiacong Shen</name>
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<author><name sortKey="Yuan, Weiyong" sort="Yuan, Weiyong" uniqKey="Yuan W" first="Weiyong" last="Yuan">Weiyong Yuan</name>
<affiliation><nlm:affiliation>Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, People's Republic of China.</nlm:affiliation>
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<author><name sortKey="Ji, Jian" sort="Ji, Jian" uniqKey="Ji J" first="Jian" last="Ji">Jian Ji</name>
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<author><name sortKey="Fu, Jinhong" sort="Fu, Jinhong" uniqKey="Fu J" first="Jinhong" last="Fu">Jinhong Fu</name>
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<author><name sortKey="Shen, Jiacong" sort="Shen, Jiacong" uniqKey="Shen J" first="Jiacong" last="Shen">Jiacong Shen</name>
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<series><title level="j">Journal of biomedical materials research. Part B, Applied biomaterials</title>
<idno type="eISSN">1552-4981</idno>
<imprint><date when="2008" type="published">2008</date>
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<term>Chitosan (chemistry)</term>
<term>Escherichia coli (growth & development)</term>
<term>Membranes, Artificial (MeSH)</term>
<term>Microbial Sensitivity Tests (methods)</term>
<term>Nanoparticles (chemistry)</term>
<term>Photochemistry (MeSH)</term>
<term>Photosensitizing Agents (chemistry)</term>
<term>Silver (chemistry)</term>
<term>Time Factors (MeSH)</term>
<term>Titanium (chemistry)</term>
<term>Ultraviolet Rays (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Anti-Bacterial Agents</term>
<term>Chitosan</term>
<term>Photosensitizing Agents</term>
<term>Silver</term>
<term>Titanium</term>
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<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nanoparticles</term>
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<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Escherichia coli</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Microbial Sensitivity Tests</term>
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<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Membranes, Artificial</term>
<term>Photochemistry</term>
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<front><div type="abstract" xml:lang="en">A multifunctional multilayered film containing TiO(2) nanoparticles as contact-active antibacterial agent and nanosilver as a release-active antibacterial agent was fabricated via layer-by-layer assembly. TiO(2) nanoparticles with the anatase crystalline dominant structure were synthesized via a sol-gel method. The QCM, AFM, and contact angle measurement results indicated that the TiO(2) nanoparticle-chitosan was successfully assembled with heparin via layer-by-layer assembly. The UV visible spectroscopy demonstrated that the silver ions could be loaded into the multilayers and in situ synthesize silver nanoparticles in the multilayers template. The short-term antibacterial assay showed the TiO(2)-chitosan/heparin multilayers loaded with nanosilver was bactericidal both in the low intensity UV light and in the dark. The long-term antibacterial assay indicated although the antibacterial in dark decreased with the PBS immersion time, the hybrid multilayered films sustained the long-term antibacterial in the low intensity UV light.</div>
</front>
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<Month>07</Month>
<Day>01</Day>
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<DateRevised><Year>2020</Year>
<Month>09</Month>
<Day>30</Day>
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<JournalIssue CitedMedium="Internet"><Volume>85</Volume>
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<Title>Journal of biomedical materials research. Part B, Applied biomaterials</Title>
<ISOAbbreviation>J Biomed Mater Res B Appl Biomater</ISOAbbreviation>
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<ArticleTitle>A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating.</ArticleTitle>
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<Abstract><AbstractText>A multifunctional multilayered film containing TiO(2) nanoparticles as contact-active antibacterial agent and nanosilver as a release-active antibacterial agent was fabricated via layer-by-layer assembly. TiO(2) nanoparticles with the anatase crystalline dominant structure were synthesized via a sol-gel method. The QCM, AFM, and contact angle measurement results indicated that the TiO(2) nanoparticle-chitosan was successfully assembled with heparin via layer-by-layer assembly. The UV visible spectroscopy demonstrated that the silver ions could be loaded into the multilayers and in situ synthesize silver nanoparticles in the multilayers template. The short-term antibacterial assay showed the TiO(2)-chitosan/heparin multilayers loaded with nanosilver was bactericidal both in the low intensity UV light and in the dark. The long-term antibacterial assay indicated although the antibacterial in dark decreased with the PBS immersion time, the hybrid multilayered films sustained the long-term antibacterial in the low intensity UV light.</AbstractText>
<CopyrightInformation>Copyright 2007 Wiley Periodicals, Inc.</CopyrightInformation>
</Abstract>
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