Silver nanoparticles strongly enhance and restore bactericidal activity of inactive antibiotics against multiresistant Enterobacteriaceae.
Identifieur interne : 000685 ( Main/Corpus ); précédent : 000684; suivant : 000686Silver nanoparticles strongly enhance and restore bactericidal activity of inactive antibiotics against multiresistant Enterobacteriaceae.
Auteurs : Aleš Paná Ek ; Monika Smékalová ; Renata Ve E Ová ; Kate Ina Bogdanová ; Magdaléna Röderová ; Milan Kolá ; Martina Kilianová ; Šárka Hradilová ; Jens P. Froning ; Markéta Havrdová ; Robert Prucek ; Radek Zbo Il ; Libor KvítekSource :
- Colloids and surfaces. B, Biointerfaces [ 1873-4367 ] ; 2016.
English descriptors
- KwdEn :
- Anti-Bacterial Agents (pharmacology), Cefotaxime (pharmacology), Ceftazidime (pharmacology), Ciprofloxacin (pharmacology), Drug Resistance, Multiple, Bacterial (drug effects), Drug Resistance, Multiple, Bacterial (genetics), Drug Synergism (MeSH), Escherichia coli (drug effects), Escherichia coli (enzymology), Escherichia coli (genetics), Escherichia coli (growth & development), Gene Expression (MeSH), Gentamicins (pharmacology), Klebsiella pneumoniae (drug effects), Klebsiella pneumoniae (enzymology), Klebsiella pneumoniae (genetics), Klebsiella pneumoniae (growth & development), Meropenem (MeSH), Metal Nanoparticles (chemistry), Metal Nanoparticles (toxicity), Microbial Sensitivity Tests (MeSH), Silver (pharmacology), Thienamycins (pharmacology), beta-Lactamases (genetics), beta-Lactamases (metabolism).
- MESH :
- chemical , genetics : beta-Lactamases.
- chemical , metabolism : beta-Lactamases.
- chemical , pharmacology : Anti-Bacterial Agents, Cefotaxime, Ceftazidime, Ciprofloxacin, Gentamicins, Silver, Thienamycins.
- chemistry : Metal Nanoparticles.
- drug effects : Drug Resistance, Multiple, Bacterial, Escherichia coli, Klebsiella pneumoniae.
- enzymology : Escherichia coli, Klebsiella pneumoniae.
- genetics : Drug Resistance, Multiple, Bacterial, Escherichia coli, Klebsiella pneumoniae.
- growth & development : Escherichia coli, Klebsiella pneumoniae.
- toxicity : Metal Nanoparticles.
- Drug Synergism, Gene Expression, Meropenem, Microbial Sensitivity Tests.
Abstract
Bacterial resistance to conventional antibiotics is currently one of the most important healthcare issues, and has serious negative impacts on medical practice. This study presents a potential solution to this problem, using the strong synergistic effects of antibiotics combined with silver nanoparticles (NPs). Silver NPs inhibit bacterial growth via a multilevel mode of antibacterial action at concentrations ranging from a few ppm to tens of ppm. Silver NPs strongly enhanced antibacterial activity against multiresistant, β-lactamase and carbapenemase-producing Enterobacteriaceae when combined with the following antibiotics: cefotaxime, ceftazidime, meropenem, ciprofloxacin and gentamicin. All the antibiotics, when combined with silver NPs, showed enhanced antibacterial activity at concentrations far below the minimum inhibitory concentrations (tenths to hundredths of one ppm) of individual antibiotics and silver NPs. The enhanced activity of antibiotics combined with silver NPs, especially meropenem, was weaker against non-resistant bacteria than against resistant bacteria. The double disk synergy test showed that bacteria produced no β-lactamase when treated with antibiotics combined with silver NPs. Low silver concentrations were required for effective enhancement of antibacterial activity against multiresistant bacteria. These low silver concentrations showed no cytotoxic effect towards mammalian cells, an important feature for potential medical applications.
DOI: 10.1016/j.colsurfb.2016.03.007
PubMed: 26970828
Links to Exploration step
pubmed:26970828Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Silver nanoparticles strongly enhance and restore bactericidal activity of inactive antibiotics against multiresistant Enterobacteriaceae.</title><author><name sortKey="Pana Ek, Ales" sort="Pana Ek, Ales" uniqKey="Pana Ek A" first="Aleš" last="Paná Ek">Aleš Paná Ek</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic. Electronic address: ales.panacek@upol.cz.</nlm:affiliation></affiliation></author><author><name sortKey="Smekalova, Monika" sort="Smekalova, Monika" uniqKey="Smekalova M" first="Monika" last="Smékalová">Monika Smékalová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Ve E Ova, Renata" sort="Ve E Ova, Renata" uniqKey="Ve E Ova R" first="Renata" last="Ve E Ová">Renata Ve E Ová</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Bogdanova, Kate Ina" sort="Bogdanova, Kate Ina" uniqKey="Bogdanova K" first="Kate Ina" last="Bogdanová">Kate Ina Bogdanová</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Roderova, Magdalena" sort="Roderova, Magdalena" uniqKey="Roderova M" first="Magdaléna" last="Röderová">Magdaléna Röderová</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Kola, Milan" sort="Kola, Milan" uniqKey="Kola M" first="Milan" last="Kolá">Milan Kolá</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Kilianova, Martina" sort="Kilianova, Martina" uniqKey="Kilianova M" first="Martina" last="Kilianová">Martina Kilianová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Hradilova, Sarka" sort="Hradilova, Sarka" uniqKey="Hradilova S" first="Šárka" last="Hradilová">Šárka Hradilová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Froning, Jens P" sort="Froning, Jens P" uniqKey="Froning J" first="Jens P" last="Froning">Jens P. Froning</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Havrdova, Marketa" sort="Havrdova, Marketa" uniqKey="Havrdova M" first="Markéta" last="Havrdová">Markéta Havrdová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Experimental Physics, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Prucek, Robert" sort="Prucek, Robert" uniqKey="Prucek R" first="Robert" last="Prucek">Robert Prucek</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Zbo Il, Radek" sort="Zbo Il, Radek" uniqKey="Zbo Il R" first="Radek" last="Zbo Il">Radek Zbo Il</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Kvitek, Libor" sort="Kvitek, Libor" uniqKey="Kvitek L" first="Libor" last="Kvítek">Libor Kvítek</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26970828</idno><idno type="pmid">26970828</idno><idno type="doi">10.1016/j.colsurfb.2016.03.007</idno><idno type="wicri:Area/Main/Corpus">000685</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000685</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Silver nanoparticles strongly enhance and restore bactericidal activity of inactive antibiotics against multiresistant Enterobacteriaceae.</title><author><name sortKey="Pana Ek, Ales" sort="Pana Ek, Ales" uniqKey="Pana Ek A" first="Aleš" last="Paná Ek">Aleš Paná Ek</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic. Electronic address: ales.panacek@upol.cz.</nlm:affiliation></affiliation></author><author><name sortKey="Smekalova, Monika" sort="Smekalova, Monika" uniqKey="Smekalova M" first="Monika" last="Smékalová">Monika Smékalová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Ve E Ova, Renata" sort="Ve E Ova, Renata" uniqKey="Ve E Ova R" first="Renata" last="Ve E Ová">Renata Ve E Ová</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Bogdanova, Kate Ina" sort="Bogdanova, Kate Ina" uniqKey="Bogdanova K" first="Kate Ina" last="Bogdanová">Kate Ina Bogdanová</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Roderova, Magdalena" sort="Roderova, Magdalena" uniqKey="Roderova M" first="Magdaléna" last="Röderová">Magdaléna Röderová</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Kola, Milan" sort="Kola, Milan" uniqKey="Kola M" first="Milan" last="Kolá">Milan Kolá</name><affiliation><nlm:affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Kilianova, Martina" sort="Kilianova, Martina" uniqKey="Kilianova M" first="Martina" last="Kilianová">Martina Kilianová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Hradilova, Sarka" sort="Hradilova, Sarka" uniqKey="Hradilova S" first="Šárka" last="Hradilová">Šárka Hradilová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Froning, Jens P" sort="Froning, Jens P" uniqKey="Froning J" first="Jens P" last="Froning">Jens P. Froning</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Havrdova, Marketa" sort="Havrdova, Marketa" uniqKey="Havrdova M" first="Markéta" last="Havrdová">Markéta Havrdová</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Experimental Physics, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Prucek, Robert" sort="Prucek, Robert" uniqKey="Prucek R" first="Robert" last="Prucek">Robert Prucek</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Zbo Il, Radek" sort="Zbo Il, Radek" uniqKey="Zbo Il R" first="Radek" last="Zbo Il">Radek Zbo Il</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author><author><name sortKey="Kvitek, Libor" sort="Kvitek, Libor" uniqKey="Kvitek L" first="Libor" last="Kvítek">Libor Kvítek</name><affiliation><nlm:affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Colloids and surfaces. B, Biointerfaces</title><idno type="eISSN">1873-4367</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Bacterial Agents (pharmacology)</term><term>Cefotaxime (pharmacology)</term><term>Ceftazidime (pharmacology)</term><term>Ciprofloxacin (pharmacology)</term><term>Drug Resistance, Multiple, Bacterial (drug effects)</term><term>Drug Resistance, Multiple, Bacterial (genetics)</term><term>Drug Synergism (MeSH)</term><term>Escherichia coli (drug effects)</term><term>Escherichia coli (enzymology)</term><term>Escherichia coli (genetics)</term><term>Escherichia coli (growth & development)</term><term>Gene Expression (MeSH)</term><term>Gentamicins (pharmacology)</term><term>Klebsiella pneumoniae (drug effects)</term><term>Klebsiella pneumoniae (enzymology)</term><term>Klebsiella pneumoniae (genetics)</term><term>Klebsiella pneumoniae (growth & development)</term><term>Meropenem (MeSH)</term><term>Metal Nanoparticles (chemistry)</term><term>Metal Nanoparticles (toxicity)</term><term>Microbial Sensitivity Tests (MeSH)</term><term>Silver (pharmacology)</term><term>Thienamycins (pharmacology)</term><term>beta-Lactamases (genetics)</term><term>beta-Lactamases (metabolism)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>beta-Lactamases</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>beta-Lactamases</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Cefotaxime</term><term>Ceftazidime</term><term>Ciprofloxacin</term><term>Gentamicins</term><term>Silver</term><term>Thienamycins</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Metal Nanoparticles</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Drug Resistance, Multiple, Bacterial</term><term>Escherichia coli</term><term>Klebsiella pneumoniae</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Escherichia coli</term><term>Klebsiella pneumoniae</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Drug Resistance, Multiple, Bacterial</term><term>Escherichia coli</term><term>Klebsiella pneumoniae</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Escherichia coli</term><term>Klebsiella pneumoniae</term></keywords><keywords scheme="MESH" qualifier="toxicity" xml:lang="en"><term>Metal Nanoparticles</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Drug Synergism</term><term>Gene Expression</term><term>Meropenem</term><term>Microbial Sensitivity Tests</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Bacterial resistance to conventional antibiotics is currently one of the most important healthcare issues, and has serious negative impacts on medical practice. This study presents a potential solution to this problem, using the strong synergistic effects of antibiotics combined with silver nanoparticles (NPs). Silver NPs inhibit bacterial growth via a multilevel mode of antibacterial action at concentrations ranging from a few ppm to tens of ppm. Silver NPs strongly enhanced antibacterial activity against multiresistant, β-lactamase and carbapenemase-producing Enterobacteriaceae when combined with the following antibiotics: cefotaxime, ceftazidime, meropenem, ciprofloxacin and gentamicin. All the antibiotics, when combined with silver NPs, showed enhanced antibacterial activity at concentrations far below the minimum inhibitory concentrations (tenths to hundredths of one ppm) of individual antibiotics and silver NPs. The enhanced activity of antibiotics combined with silver NPs, especially meropenem, was weaker against non-resistant bacteria than against resistant bacteria. The double disk synergy test showed that bacteria produced no β-lactamase when treated with antibiotics combined with silver NPs. Low silver concentrations were required for effective enhancement of antibacterial activity against multiresistant bacteria. These low silver concentrations showed no cytotoxic effect towards mammalian cells, an important feature for potential medical applications. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26970828</PMID><DateCompleted><Year>2016</Year><Month>12</Month><Day>27</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-4367</ISSN><JournalIssue CitedMedium="Internet"><Volume>142</Volume><PubDate><Year>2016</Year><Month>Jun</Month><Day>01</Day></PubDate></JournalIssue><Title>Colloids and surfaces. B, Biointerfaces</Title><ISOAbbreviation>Colloids Surf B Biointerfaces</ISOAbbreviation></Journal><ArticleTitle>Silver nanoparticles strongly enhance and restore bactericidal activity of inactive antibiotics against multiresistant Enterobacteriaceae.</ArticleTitle><Pagination><MedlinePgn>392-399</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0927-7765(16)30151-5</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.colsurfb.2016.03.007</ELocationID><Abstract><AbstractText>Bacterial resistance to conventional antibiotics is currently one of the most important healthcare issues, and has serious negative impacts on medical practice. This study presents a potential solution to this problem, using the strong synergistic effects of antibiotics combined with silver nanoparticles (NPs). Silver NPs inhibit bacterial growth via a multilevel mode of antibacterial action at concentrations ranging from a few ppm to tens of ppm. Silver NPs strongly enhanced antibacterial activity against multiresistant, β-lactamase and carbapenemase-producing Enterobacteriaceae when combined with the following antibiotics: cefotaxime, ceftazidime, meropenem, ciprofloxacin and gentamicin. All the antibiotics, when combined with silver NPs, showed enhanced antibacterial activity at concentrations far below the minimum inhibitory concentrations (tenths to hundredths of one ppm) of individual antibiotics and silver NPs. The enhanced activity of antibiotics combined with silver NPs, especially meropenem, was weaker against non-resistant bacteria than against resistant bacteria. The double disk synergy test showed that bacteria produced no β-lactamase when treated with antibiotics combined with silver NPs. Low silver concentrations were required for effective enhancement of antibacterial activity against multiresistant bacteria. These low silver concentrations showed no cytotoxic effect towards mammalian cells, an important feature for potential medical applications. </AbstractText><CopyrightInformation>Copyright © 2016 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Panáček</LastName><ForeName>Aleš</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic. Electronic address: ales.panacek@upol.cz.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smékalová</LastName><ForeName>Monika</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Večeřová</LastName><ForeName>Renata</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bogdanová</LastName><ForeName>Kateřina</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Röderová</LastName><ForeName>Magdaléna</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kolář</LastName><ForeName>Milan</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Hněvotínská 5, 775 15 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kilianová</LastName><ForeName>Martina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hradilová</LastName><ForeName>Šárka</ForeName><Initials>Š</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Froning</LastName><ForeName>Jens P</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Havrdová</LastName><ForeName>Markéta</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Experimental Physics, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prucek</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zbořil</LastName><ForeName>Radek</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kvítek</LastName><ForeName>Libor</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacký University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>03</Month><Day>04</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Colloids Surf B Biointerfaces</MedlineTA><NlmUniqueID>9315133</NlmUniqueID><ISSNLinking>0927-7765</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005839">Gentamicins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013845">Thienamycins</NameOfSubstance></Chemical><Chemical><RegistryNumber>3M4G523W1G</RegistryNumber><NameOfSubstance UI="D012834">Silver</NameOfSubstance></Chemical><Chemical><RegistryNumber>5E8K9I0O4U</RegistryNumber><NameOfSubstance UI="D002939">Ciprofloxacin</NameOfSubstance></Chemical><Chemical><RegistryNumber>9M416Z9QNR</RegistryNumber><NameOfSubstance UI="D002442">Ceftazidime</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.5.2.6</RegistryNumber><NameOfSubstance UI="D001618">beta-Lactamases</NameOfSubstance></Chemical><Chemical><RegistryNumber>FV9J3JU8B1</RegistryNumber><NameOfSubstance UI="D000077731">Meropenem</NameOfSubstance></Chemical><Chemical><RegistryNumber>N2GI8B1GK7</RegistryNumber><NameOfSubstance UI="D002439">Cefotaxime</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002439" MajorTopicYN="N">Cefotaxime</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002442" MajorTopicYN="N">Ceftazidime</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002939" MajorTopicYN="N">Ciprofloxacin</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D024901" MajorTopicYN="N">Drug Resistance, Multiple, Bacterial</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004357" MajorTopicYN="N">Drug Synergism</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004926" MajorTopicYN="N">Escherichia coli</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName><QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015870" MajorTopicYN="N">Gene Expression</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005839" MajorTopicYN="N">Gentamicins</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007711" MajorTopicYN="N">Klebsiella pneumoniae</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName><QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000077731" MajorTopicYN="N">Meropenem</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053768" MajorTopicYN="N">Metal Nanoparticles</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008826" MajorTopicYN="N">Microbial Sensitivity Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012834" MajorTopicYN="N">Silver</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013845" MajorTopicYN="N">Thienamycins</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001618" MajorTopicYN="N">beta-Lactamases</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Antibiotic</Keyword><Keyword MajorTopicYN="N">Cytotoxicity</Keyword><Keyword MajorTopicYN="N">Resistant bacteria</Keyword><Keyword MajorTopicYN="N">Silver nanoparticle</Keyword><Keyword MajorTopicYN="N">Synergism</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>10</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>03</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>03</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>3</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>3</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>12</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26970828</ArticleId><ArticleId IdType="pii">S0927-7765(16)30151-5</ArticleId><ArticleId IdType="doi">10.1016/j.colsurfb.2016.03.007</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Terre/explor/SilverBacteriV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000685 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000685 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Terre
|area= SilverBacteriV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= pubmed:26970828
|texte= Silver nanoparticles strongly enhance and restore bactericidal activity of inactive antibiotics against multiresistant Enterobacteriaceae.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Corpus/RBID.i -Sk "pubmed:26970828" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a SilverBacteriV1
| This area was generated with Dilib version V0.6.38. |  |