Enhanced silver loaded antibacterial titanium implant coating with novel hierarchical effect.
Identifieur interne : 000454 ( Main/Corpus ); précédent : 000453; suivant : 000455Enhanced silver loaded antibacterial titanium implant coating with novel hierarchical effect.
Auteurs : Yanxian Zhang ; Chaofang Dong ; Sefei Yang ; Te-Wei Chiu ; Junsheng Wu ; Kui Xiao ; Yunhua Huang ; Xiaogang LiSource :
- Journal of biomaterials applications [ 1530-8022 ] ; 2018.
English descriptors
- KwdEn :
- Animals (MeSH), Anti-Bacterial Agents (administration & dosage), Anti-Bacterial Agents (pharmacology), Cell Line (MeSH), Coated Materials, Biocompatible (chemistry), Delayed-Action Preparations (chemistry), Humans (MeSH), Indoles (chemistry), Mice (MeSH), Microbial Sensitivity Tests (MeSH), Nanotubes (chemistry), Polymers (chemistry), Prostheses and Implants (MeSH), Silver (administration & dosage), Silver (pharmacology), Staphylococcal Infections (drug therapy), Staphylococcal Infections (prevention & control), Staphylococcus aureus (drug effects), Surface Properties (MeSH), Titanium (chemistry).
- MESH :
- chemical , administration & dosage : Anti-Bacterial Agents, Silver.
- chemical , chemistry : Coated Materials, Biocompatible, Delayed-Action Preparations, Indoles, Polymers, Titanium.
- chemical , pharmacology : Anti-Bacterial Agents, Silver.
- chemistry : Nanotubes.
- drug effects : Staphylococcus aureus.
- drug therapy : Staphylococcal Infections.
- prevention & control : Staphylococcal Infections.
- Animals, Cell Line, Humans, Mice, Microbial Sensitivity Tests, Prostheses and Implants, Surface Properties.
Abstract
In this study, we present a novel strategy for hierarchical antibacterial implant coating by controlling structural and componential features as regulators of surface bactericidal property. Anodized titanium dioxide nanotubes and self-polymerized polydopamine were both used as preliminary antibacterial agents with a significant positive effect on surface bioactivity. At the same time, the storage capacity of nanotubes and the in situ reduction activity of polydopamine can introduce large amounts of strong attached silver nanoparticles for enhanced stable antibacterial performance. The surface morphology, chemical composition, and hydrophilicity had been thoroughly characterized. The sustained silver release performances were continuously monitored. The successively in vitro inhibition on Staphylococcus aureus growth of titanium dioxide nanotube, polydopamine layer and silver nanoparticles demonstrated the hierarchical antibacterial property of the final silver nanoparticles-incorporated polydopamine-modified titanium dioxide nanotube coating (silver/polydopamine/nanotube). Moreover, the bioactivity investigation indicated the vital role of polydopamine-modified titanium dioxide nanotube coating on preserving healthy osteoblast activity at the implant interface. The unique hierarchical coating for titanium implant may be a promising method to maximize antibacterial capacity and maintain good cellular activity at the same time.
DOI: 10.1177/0885328218755538
PubMed: 29417864
Links to Exploration step
pubmed:29417864Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Enhanced silver loaded antibacterial titanium implant coating with novel hierarchical effect.</title><author><name sortKey="Zhang, Yanxian" sort="Zhang, Yanxian" uniqKey="Zhang Y" first="Yanxian" last="Zhang">Yanxian Zhang</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Dong, Chaofang" sort="Dong, Chaofang" uniqKey="Dong C" first="Chaofang" last="Dong">Chaofang Dong</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Yang, Sefei" sort="Yang, Sefei" uniqKey="Yang S" first="Sefei" last="Yang">Sefei Yang</name><affiliation><nlm:affiliation>2 Department of Stomatology, The PLA General Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Chiu, Te Wei" sort="Chiu, Te Wei" uniqKey="Chiu T" first="Te-Wei" last="Chiu">Te-Wei Chiu</name><affiliation><nlm:affiliation>3 Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, Zhongxiao E. Rd., Taipei, Taiwan.</nlm:affiliation></affiliation></author><author><name sortKey="Wu, Junsheng" sort="Wu, Junsheng" uniqKey="Wu J" first="Junsheng" last="Wu">Junsheng Wu</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Xiao, Kui" sort="Xiao, Kui" uniqKey="Xiao K" first="Kui" last="Xiao">Kui Xiao</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Huang, Yunhua" sort="Huang, Yunhua" uniqKey="Huang Y" first="Yunhua" last="Huang">Yunhua Huang</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Xiaogang" sort="Li, Xiaogang" uniqKey="Li X" first="Xiaogang" last="Li">Xiaogang Li</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:29417864</idno><idno type="pmid">29417864</idno><idno type="doi">10.1177/0885328218755538</idno><idno type="wicri:Area/Main/Corpus">000454</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000454</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Enhanced silver loaded antibacterial titanium implant coating with novel hierarchical effect.</title><author><name sortKey="Zhang, Yanxian" sort="Zhang, Yanxian" uniqKey="Zhang Y" first="Yanxian" last="Zhang">Yanxian Zhang</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Dong, Chaofang" sort="Dong, Chaofang" uniqKey="Dong C" first="Chaofang" last="Dong">Chaofang Dong</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Yang, Sefei" sort="Yang, Sefei" uniqKey="Yang S" first="Sefei" last="Yang">Sefei Yang</name><affiliation><nlm:affiliation>2 Department of Stomatology, The PLA General Hospital, Beijing, China.</nlm:affiliation></affiliation></author><author><name sortKey="Chiu, Te Wei" sort="Chiu, Te Wei" uniqKey="Chiu T" first="Te-Wei" last="Chiu">Te-Wei Chiu</name><affiliation><nlm:affiliation>3 Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, Zhongxiao E. Rd., Taipei, Taiwan.</nlm:affiliation></affiliation></author><author><name sortKey="Wu, Junsheng" sort="Wu, Junsheng" uniqKey="Wu J" first="Junsheng" last="Wu">Junsheng Wu</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Xiao, Kui" sort="Xiao, Kui" uniqKey="Xiao K" first="Kui" last="Xiao">Kui Xiao</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Huang, Yunhua" sort="Huang, Yunhua" uniqKey="Huang Y" first="Yunhua" last="Huang">Yunhua Huang</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Xiaogang" sort="Li, Xiaogang" uniqKey="Li X" first="Xiaogang" last="Li">Xiaogang Li</name><affiliation><nlm:affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of biomaterials applications</title><idno type="eISSN">1530-8022</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term><term>Anti-Bacterial Agents (administration & dosage)</term><term>Anti-Bacterial Agents (pharmacology)</term><term>Cell Line (MeSH)</term><term>Coated Materials, Biocompatible (chemistry)</term><term>Delayed-Action Preparations (chemistry)</term><term>Humans (MeSH)</term><term>Indoles (chemistry)</term><term>Mice (MeSH)</term><term>Microbial Sensitivity Tests (MeSH)</term><term>Nanotubes (chemistry)</term><term>Polymers (chemistry)</term><term>Prostheses and Implants (MeSH)</term><term>Silver (administration & dosage)</term><term>Silver (pharmacology)</term><term>Staphylococcal Infections (drug therapy)</term><term>Staphylococcal Infections (prevention & control)</term><term>Staphylococcus aureus (drug effects)</term><term>Surface Properties (MeSH)</term><term>Titanium (chemistry)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Silver</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Coated Materials, Biocompatible</term><term>Delayed-Action Preparations</term><term>Indoles</term><term>Polymers</term><term>Titanium</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Silver</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nanotubes</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Staphylococcus aureus</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Staphylococcal Infections</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Staphylococcal Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Line</term><term>Humans</term><term>Mice</term><term>Microbial Sensitivity Tests</term><term>Prostheses and Implants</term><term>Surface Properties</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In this study, we present a novel strategy for hierarchical antibacterial implant coating by controlling structural and componential features as regulators of surface bactericidal property. Anodized titanium dioxide nanotubes and self-polymerized polydopamine were both used as preliminary antibacterial agents with a significant positive effect on surface bioactivity. At the same time, the storage capacity of nanotubes and the in situ reduction activity of polydopamine can introduce large amounts of strong attached silver nanoparticles for enhanced stable antibacterial performance. The surface morphology, chemical composition, and hydrophilicity had been thoroughly characterized. The sustained silver release performances were continuously monitored. The successively in vitro inhibition on Staphylococcus aureus growth of titanium dioxide nanotube, polydopamine layer and silver nanoparticles demonstrated the hierarchical antibacterial property of the final silver nanoparticles-incorporated polydopamine-modified titanium dioxide nanotube coating (silver/polydopamine/nanotube). Moreover, the bioactivity investigation indicated the vital role of polydopamine-modified titanium dioxide nanotube coating on preserving healthy osteoblast activity at the implant interface. The unique hierarchical coating for titanium implant may be a promising method to maximize antibacterial capacity and maintain good cellular activity at the same time.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29417864</PMID><DateCompleted><Year>2019</Year><Month>07</Month><Day>16</Day></DateCompleted><DateRevised><Year>2019</Year><Month>07</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1530-8022</ISSN><JournalIssue CitedMedium="Internet"><Volume>32</Volume><Issue>9</Issue><PubDate><Year>2018</Year><Month>04</Month></PubDate></JournalIssue><Title>Journal of biomaterials applications</Title><ISOAbbreviation>J Biomater Appl</ISOAbbreviation></Journal><ArticleTitle>Enhanced silver loaded antibacterial titanium implant coating with novel hierarchical effect.</ArticleTitle><Pagination><MedlinePgn>1289-1299</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1177/0885328218755538</ELocationID><Abstract><AbstractText>In this study, we present a novel strategy for hierarchical antibacterial implant coating by controlling structural and componential features as regulators of surface bactericidal property. Anodized titanium dioxide nanotubes and self-polymerized polydopamine were both used as preliminary antibacterial agents with a significant positive effect on surface bioactivity. At the same time, the storage capacity of nanotubes and the in situ reduction activity of polydopamine can introduce large amounts of strong attached silver nanoparticles for enhanced stable antibacterial performance. The surface morphology, chemical composition, and hydrophilicity had been thoroughly characterized. The sustained silver release performances were continuously monitored. The successively in vitro inhibition on Staphylococcus aureus growth of titanium dioxide nanotube, polydopamine layer and silver nanoparticles demonstrated the hierarchical antibacterial property of the final silver nanoparticles-incorporated polydopamine-modified titanium dioxide nanotube coating (silver/polydopamine/nanotube). Moreover, the bioactivity investigation indicated the vital role of polydopamine-modified titanium dioxide nanotube coating on preserving healthy osteoblast activity at the implant interface. The unique hierarchical coating for titanium implant may be a promising method to maximize antibacterial capacity and maintain good cellular activity at the same time.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Yanxian</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dong</LastName><ForeName>Chaofang</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Sefei</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>2 Department of Stomatology, The PLA General Hospital, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chiu</LastName><ForeName>Te-Wei</ForeName><Initials>TW</Initials><AffiliationInfo><Affiliation>3 Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, Zhongxiao E. Rd., Taipei, Taiwan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>Junsheng</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xiao</LastName><ForeName>Kui</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huang</LastName><ForeName>Yunhua</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Xiaogang</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>1 Corrosion and Protection Center, Key Laboratory for Corrosion and Protection (MOE), 12507 University of Science and Technology, Beijing , China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>02</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Biomater Appl</MedlineTA><NlmUniqueID>8813912</NlmUniqueID><ISSNLinking>0885-3282</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D020099">Coated Materials, Biocompatible</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D003692">Delayed-Action Preparations</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007211">Indoles</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011108">Polymers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C568283">polydopamine</NameOfSubstance></Chemical><Chemical><RegistryNumber>15FIX9V2JP</RegistryNumber><NameOfSubstance UI="C009495">titanium dioxide</NameOfSubstance></Chemical><Chemical><RegistryNumber>3M4G523W1G</RegistryNumber><NameOfSubstance UI="D012834">Silver</NameOfSubstance></Chemical><Chemical><RegistryNumber>D1JT611TNE</RegistryNumber><NameOfSubstance UI="D014025">Titanium</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002460" MajorTopicYN="N">Cell Line</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020099" MajorTopicYN="N">Coated Materials, Biocompatible</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003692" MajorTopicYN="N">Delayed-Action Preparations</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007211" MajorTopicYN="N">Indoles</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008826" MajorTopicYN="N">Microbial Sensitivity Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D043942" MajorTopicYN="N">Nanotubes</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011108" MajorTopicYN="N">Polymers</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019736" MajorTopicYN="N">Prostheses and Implants</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012834" MajorTopicYN="N">Silver</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013203" MajorTopicYN="N">Staphylococcal Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013211" MajorTopicYN="N">Staphylococcus aureus</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013499" MajorTopicYN="N">Surface Properties</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014025" MajorTopicYN="N">Titanium</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Titanium implant</Keyword><Keyword MajorTopicYN="Y">antibacterial coating</Keyword><Keyword MajorTopicYN="Y">hierarchical effect</Keyword><Keyword MajorTopicYN="Y">sliver nanoparticles</Keyword><Keyword MajorTopicYN="Y">sustained release</Keyword><Keyword MajorTopicYN="Y">titanium dioxide nanotubes</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>2</Month><Day>9</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>7</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>2</Month><Day>9</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29417864</ArticleId><ArticleId IdType="doi">10.1177/0885328218755538</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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