Primitive megalencephaly in children: Natural history, medium term prognosis with special reference to external hydrocephalus
Identifieur interne : 001558 ( Istex/Corpus ); précédent : 001557; suivant : 001559Primitive megalencephaly in children: Natural history, medium term prognosis with special reference to external hydrocephalus
Auteurs : B. Laubscher ; T. Deonna ; A. Uske ; G. Van MelleSource :
- European Journal of Pediatrics [ 0340-6199 ] ; 1990-04-01.
Abstract
Abstract: We studied 74 children with primitive megalencephaly retrospectively with attention directed to familial megalencephaly, birth history, enlarged pericerebral subarachnoid space (SAS) (idiopathic external hydrocephalus), head and statural growth dynamics, developmental and school prognosis, morphological findings and development of subdural haematoma. In the megalencephalic children, no significant differences were found between those with normal or those with enlarged pericerebral SAS. Out of 62, 31 children (50%) were already megalencephalic at birth. Of 74, 37 children (50%) showed variable degrees of developmental delay which in 18 was transient. Eight out of 74 were mentally retarded. Of 52 children at school age, 42 attend normal schools and 10, of whom 7 are mentally retarded, attend special schools. Three children showed subdural haematoma resulting from apparently minor trauma or occurring spontaneously. We suggest that idiopathic external hydrocephalus represents a variant of primitive megalencephaly with transient increase of intracranial pressure and that it could predispose to the development of idiopathic (spontaneous or non-traumatic) subdural haematoma.
Url:
DOI: 10.1007/BF01959405
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<Country>Switzerland</Country>
</OrgAddress>
</Affiliation>
<Affiliation ID="Aff2"><OrgDivision>Department of Radiology</OrgDivision>
<OrgName>Centre Hospitalier Universitaire Vaudois</OrgName>
<OrgAddress><Postcode>CH-1011</Postcode>
<City>Lausanne</City>
<Country>Switzerland</Country>
</OrgAddress>
</Affiliation>
<Affiliation ID="Aff3"><OrgDivision>Institute of Social and Preventive Medicine</OrgDivision>
<OrgName>University of Lausanne</OrgName>
<OrgAddress><Postcode>CH-1005</Postcode>
<City>Lausanne</City>
<Country>Switzerland</Country>
</OrgAddress>
</Affiliation>
</AuthorGroup>
<Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading>
<Para>We studied 74 children with primitive megalencephaly retrospectively with attention directed to familial megalencephaly, birth history, enlarged pericerebral subarachnoid space (SAS) (idiopathic external hydrocephalus), head and statural growth dynamics, developmental and school prognosis, morphological findings and development of subdural haematoma. In the megalencephalic children, no significant differences were found between those with normal or those with enlarged pericerebral SAS. Out of 62, 31 children (50%) were already megalencephalic at birth. Of 74, 37 children (50%) showed variable degrees of developmental delay which in 18 was transient. Eight out of 74 were mentally retarded. Of 52 children at school age, 42 attend normal schools and 10, of whom 7 are mentally retarded, attend special schools. Three children showed subdural haematoma resulting from apparently minor trauma or occurring spontaneously. We suggest that idiopathic external hydrocephalus represents a variant of primitive megalencephaly with transient increase of intracranial pressure and that it could predispose to the development of idiopathic (spontaneous or non-traumatic) subdural haematoma.</Para>
</Abstract>
<KeywordGroup Language="En"><Heading>Key words</Heading>
<Keyword>Childhood</Keyword>
<Keyword>Hydrocephalus</Keyword>
<Keyword>Megalencephaly</Keyword>
<Keyword>Subdural haematoma</Keyword>
</KeywordGroup>
<AbbreviationGroup><Heading>Abbreviations</Heading>
<DefinitionList><DefinitionListEntry><Term>CSF</Term>
<Description><Para>cerebrospinal fluid</Para>
</Description>
</DefinitionListEntry>
<DefinitionListEntry><Term>DD</Term>
<Description><Para>developmental delay</Para>
</Description>
</DefinitionListEntry>
<DefinitionListEntry><Term>IEH</Term>
<Description><Para>idiopathic external hydrocephalus</Para>
</Description>
</DefinitionListEntry>
<DefinitionListEntry><Term>OFC</Term>
<Description><Para>occipitofrontal circumference</Para>
</Description>
</DefinitionListEntry>
<DefinitionListEntry><Term>PMG</Term>
<Description><Para>primitive megalencephaly</Para>
</Description>
</DefinitionListEntry>
<DefinitionListEntry><Term>SAS</Term>
<Description><Para>subarachnoid space</Para>
</Description>
</DefinitionListEntry>
</DefinitionList>
</AbbreviationGroup>
<ArticleNote Type="Misc"><SimplePara>This work has been presented in part at the Société de Neurologie Infantile, Tlemcen, Algeria, November 1987</SimplePara>
</ArticleNote>
</ArticleHeader>
<NoBody></NoBody>
</Article>
</Issue>
</Volume>
</Journal>
</Publisher>
</istex:document>
</istex:metadataXml>
<mods version="3.6"><titleInfo lang="en"><title>Primitive megalencephaly in children: Natural history, medium term prognosis with special reference to external hydrocephalus</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en"><title>Primitive megalencephaly in children: Natural history, medium term prognosis with special reference to external hydrocephalus</title>
</titleInfo>
<name type="personal"><namePart type="given">B.</namePart>
<namePart type="family">Laubscher</namePart>
<affiliation>Department of Paediatrics (Neuropaediatric Unit), Centre Hospitalier Universitaire Vaudois, CH-1011, Lausanne, Switzerland</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal" displayLabel="corresp"><namePart type="given">T.</namePart>
<namePart type="family">Deonna</namePart>
<affiliation>Department of Paediatrics (Neuropaediatric Unit), Centre Hospitalier Universitaire Vaudois, CH-1011, Lausanne, Switzerland</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal"><namePart type="given">A.</namePart>
<namePart type="family">Uske</namePart>
<affiliation>Department of Radiology, Centre Hospitalier Universitaire Vaudois, CH-1011, Lausanne, Switzerland</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal"><namePart type="given">G.</namePart>
<namePart type="family">van Melle</namePart>
<affiliation>Institute of Social and Preventive Medicine, University of Lausanne, CH-1005, Lausanne, Switzerland</affiliation>
<role><roleTerm type="text">author</roleTerm>
</role>
</name>
<typeOfResource>text</typeOfResource>
<genre type="research-article" displayLabel="OriginalPaper"></genre>
<originInfo><publisher>Springer-Verlag</publisher>
<place><placeTerm type="text">Berlin/Heidelberg</placeTerm>
</place>
<dateCreated encoding="w3cdtf">1989-01-13</dateCreated>
<dateIssued encoding="w3cdtf">1990-04-01</dateIssued>
<copyrightDate encoding="w3cdtf">1990</copyrightDate>
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<abstract lang="en">Abstract: We studied 74 children with primitive megalencephaly retrospectively with attention directed to familial megalencephaly, birth history, enlarged pericerebral subarachnoid space (SAS) (idiopathic external hydrocephalus), head and statural growth dynamics, developmental and school prognosis, morphological findings and development of subdural haematoma. In the megalencephalic children, no significant differences were found between those with normal or those with enlarged pericerebral SAS. Out of 62, 31 children (50%) were already megalencephalic at birth. Of 74, 37 children (50%) showed variable degrees of developmental delay which in 18 was transient. Eight out of 74 were mentally retarded. Of 52 children at school age, 42 attend normal schools and 10, of whom 7 are mentally retarded, attend special schools. Three children showed subdural haematoma resulting from apparently minor trauma or occurring spontaneously. We suggest that idiopathic external hydrocephalus represents a variant of primitive megalencephaly with transient increase of intracranial pressure and that it could predispose to the development of idiopathic (spontaneous or non-traumatic) subdural haematoma.</abstract>
<note>Neuropediatrics</note>
<subject><genre>Abbreviations</genre>
<topic>CSF : cerebrospinal fluid</topic>
<topic>DD : developmental delay</topic>
<topic>IEH : idiopathic external hydrocephalus</topic>
<topic>OFC : occipitofrontal circumference</topic>
<topic>PMG : primitive megalencephaly</topic>
<topic>SAS : subarachnoid space</topic>
</subject>
<relatedItem type="host"><titleInfo><title>European Journal of Pediatrics</title>
</titleInfo>
<titleInfo type="abbreviated"><title>Eur J Pediatr</title>
</titleInfo>
<genre type="journal" displayLabel="Archive Journal"></genre>
<originInfo><dateIssued encoding="w3cdtf">1990-04-01</dateIssued>
<copyrightDate encoding="w3cdtf">1990</copyrightDate>
</originInfo>
<subject><genre>Medicine & Public Health</genre>
<topic>Pediatrics</topic>
</subject>
<identifier type="ISSN">0340-6199</identifier>
<identifier type="eISSN">1432-1076</identifier>
<identifier type="JournalID">431</identifier>
<identifier type="IssueArticleCount">18</identifier>
<identifier type="VolumeIssueCount">12</identifier>
<part><date>1990</date>
<detail type="volume"><number>149</number>
<caption>vol.</caption>
</detail>
<detail type="issue"><number>7</number>
<caption>no.</caption>
</detail>
<extent unit="pages"><start>502</start>
<end>507</end>
</extent>
</part>
<recordInfo><recordOrigin>Springer-Verlag, 1990</recordOrigin>
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<identifier type="istex">C012DFADBF730A965F2D8529C898CD82F44236F8</identifier>
<identifier type="DOI">10.1007/BF01959405</identifier>
<identifier type="ArticleID">BF01959405</identifier>
<identifier type="ArticleID">Art14</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Springer-Verlag, 1990</accessCondition>
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