Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Parental Age and Autism Spectrum Disorders</title><author><name sortKey="Parner, Erik Thorlund" sort="Parner, Erik Thorlund" uniqKey="Parner E" first="Erik Thorlund" last="Parner">Erik Thorlund Parner</name></author><author><name sortKey="Baron Cohen, Simon" sort="Baron Cohen, Simon" uniqKey="Baron Cohen S" first="Simon" last="Baron-Cohen">Simon Baron-Cohen</name></author><author><name sortKey="Lauritsen, Marlene B" sort="Lauritsen, Marlene B" uniqKey="Lauritsen M" first="Marlene B." last="Lauritsen">Marlene B. Lauritsen</name></author><author><name sortKey="J Rgensen, Meta" sort="J Rgensen, Meta" uniqKey="J Rgensen M" first="Meta" last="J Rgensen">Meta J Rgensen</name></author><author><name sortKey="Schieve, Laura A" sort="Schieve, Laura A" uniqKey="Schieve L" first="Laura A." last="Schieve">Laura A. Schieve</name></author><author><name sortKey="Yeargin Allsopp, Marshalyn" sort="Yeargin Allsopp, Marshalyn" uniqKey="Yeargin Allsopp M" first="Marshalyn" last="Yeargin-Allsopp">Marshalyn Yeargin-Allsopp</name></author><author><name sortKey="Obel, Carsten" sort="Obel, Carsten" uniqKey="Obel C" first="Carsten" last="Obel">Carsten Obel</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22277122</idno><idno type="pmc">4562461</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562461</idno><idno type="RBID">PMC:4562461</idno><idno type="doi">10.1016/j.annepidem.2011.12.006</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">000158</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000158</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Parental Age and Autism Spectrum Disorders</title><author><name sortKey="Parner, Erik Thorlund" sort="Parner, Erik Thorlund" uniqKey="Parner E" first="Erik Thorlund" last="Parner">Erik Thorlund Parner</name></author><author><name sortKey="Baron Cohen, Simon" sort="Baron Cohen, Simon" uniqKey="Baron Cohen S" first="Simon" last="Baron-Cohen">Simon Baron-Cohen</name></author><author><name sortKey="Lauritsen, Marlene B" sort="Lauritsen, Marlene B" uniqKey="Lauritsen M" first="Marlene B." last="Lauritsen">Marlene B. Lauritsen</name></author><author><name sortKey="J Rgensen, Meta" sort="J Rgensen, Meta" uniqKey="J Rgensen M" first="Meta" last="J Rgensen">Meta J Rgensen</name></author><author><name sortKey="Schieve, Laura A" sort="Schieve, Laura A" uniqKey="Schieve L" first="Laura A." last="Schieve">Laura A. Schieve</name></author><author><name sortKey="Yeargin Allsopp, Marshalyn" sort="Yeargin Allsopp, Marshalyn" uniqKey="Yeargin Allsopp M" first="Marshalyn" last="Yeargin-Allsopp">Marshalyn Yeargin-Allsopp</name></author><author><name sortKey="Obel, Carsten" sort="Obel, Carsten" uniqKey="Obel C" first="Carsten" last="Obel">Carsten Obel</name></author></analytic><series><title level="j">Annals of epidemiology</title><idno type="ISSN">1047-2797</idno><idno type="eISSN">1873-2585</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>PURPOSE</title><p id="P1">We sought to study the possible association between parental age and autism spectrum disorder (ASD) by using both a cohort design and a sibling design.</p></sec><sec id="S2"><title>METHODS</title><p id="P2">Our cohort included all singleton births in Denmark from January 1, 1980, through December 31, 2003, a total of 1,311,736 children. Cases of ASDs were obtained from the Danish National Psychiatric Register using International Classification of Diseases (ICD)-8 and ICD-10.</p></sec><sec id="S3"><title>RESULTS</title><p id="P3">A total of 9556 children were diagnosed with an ASD. Both maternal and paternal age were associated with a greater risk of ASD in the offspring (hazard ratios ranging from 1.21 (1.10–1.34) to 1.65 (1.09–2.48) depending on combinations of parental age categories; <35, 35–39, and 40+ years). For mothers younger than 35 years, the risk of ASD increased with increasing father’s age group. For fathers younger than 35 years, the risk of ASD increased with increasing maternal age.</p></sec><sec id="S4"><title>CONCLUSIONS</title><p id="P4">We found an association between parental age and ASD in the cohort study, but the combined underlying mechanisms through which paternal and maternal age impact ASD risk do not seem to act synergistically. The results of the sibling analysis suggest that the association between parental age and ASD found in the cohort study cannot be accounted for by common genetic and environmental factors.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9100013</journal-id><journal-id journal-id-type="pubmed-jr-id">2576</journal-id><journal-id journal-id-type="nlm-ta">Ann Epidemiol</journal-id><journal-id journal-id-type="iso-abbrev">Ann Epidemiol</journal-id><journal-title-group><journal-title>Annals of epidemiology</journal-title></journal-title-group><issn pub-type="ppub">1047-2797</issn><issn pub-type="epub">1873-2585</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22277122</article-id><article-id pub-id-type="pmc">4562461</article-id><article-id pub-id-type="doi">10.1016/j.annepidem.2011.12.006</article-id><article-id pub-id-type="manuscript">HHSPA719265</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Parental Age and Autism Spectrum Disorders</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>PARNER</surname><given-names>ERIK THORLUND</given-names></name><degrees>MSc, PhD</degrees></contrib><contrib contrib-type="author"><name><surname>BARON-COHEN</surname><given-names>SIMON</given-names></name><degrees>PhD</degrees></contrib><contrib contrib-type="author"><name><surname>LAURITSEN</surname><given-names>MARLENE B.</given-names></name><degrees>MD</degrees></contrib><contrib contrib-type="author"><name><surname>JØRGENSEN</surname><given-names>META</given-names></name><degrees>MD</degrees></contrib><contrib contrib-type="author"><name><surname>SCHIEVE</surname><given-names>LAURA A.</given-names></name><degrees>PhD</degrees></contrib><contrib contrib-type="author"><name><surname>YEARGIN-ALLSOPP</surname><given-names>MARSHALYN</given-names></name><degrees>PhD</degrees></contrib><contrib contrib-type="author"><name><surname>OBEL</surname><given-names>CARSTEN</given-names></name><degrees>PhD</degrees></contrib><aff id="A1">School of Public Health, Department of Biostatistics, University of Aarhus, Denmark (E.T.P.); Autism Research Centre, Department of Psychiatry, University of Cambridge, UK (S.B.-C.); Regional Centre for Child and Adolescent Psychiatry, Aarhus University Hospital, Risskov, Denmark (M.B.L., M.J.); Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA (L.A.S., M.Y.-A.); School of Public Health, Department of General Practice, University of Aarhus, Denmark (C.O.); and School of Public Health, Center of Mental Childhealth, University of Aarhus, Denmark (C.O.)</aff></contrib-group><author-notes><corresp id="FN1">Address correspondence to: Erik Thorlund Parner, MSc, PhD, Department of Public Health, Section for Biostatistics, University of Aarhus Address: Bartholins Allé 2, DK-8000 Aarhus C, Denmark. Phone: +45 8716 7995. Fax: +45 8716 7305. <email>parner@biostat.au.dk</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>1</day><month>9</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>24</day><month>1</month><year>2012</year></pub-date><pub-date pub-type="ppub"><month>3</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>08</day><month>9</month><year>2015</year></pub-date><volume>22</volume><issue>3</issue><fpage>143</fpage><lpage>150</lpage><pmc-comment>elocation-id from pubmed: 10.1016/j.annepidem.2011.12.006</pmc-comment>
<abstract><sec id="S1"><title>PURPOSE</title><p id="P1">We sought to study the possible association between parental age and autism spectrum disorder (ASD) by using both a cohort design and a sibling design.</p></sec><sec id="S2"><title>METHODS</title><p id="P2">Our cohort included all singleton births in Denmark from January 1, 1980, through December 31, 2003, a total of 1,311,736 children. Cases of ASDs were obtained from the Danish National Psychiatric Register using International Classification of Diseases (ICD)-8 and ICD-10.</p></sec><sec id="S3"><title>RESULTS</title><p id="P3">A total of 9556 children were diagnosed with an ASD. Both maternal and paternal age were associated with a greater risk of ASD in the offspring (hazard ratios ranging from 1.21 (1.10–1.34) to 1.65 (1.09–2.48) depending on combinations of parental age categories; <35, 35–39, and 40+ years). For mothers younger than 35 years, the risk of ASD increased with increasing father’s age group. For fathers younger than 35 years, the risk of ASD increased with increasing maternal age.</p></sec><sec id="S4"><title>CONCLUSIONS</title><p id="P4">We found an association between parental age and ASD in the cohort study, but the combined underlying mechanisms through which paternal and maternal age impact ASD risk do not seem to act synergistically. The results of the sibling analysis suggest that the association between parental age and ASD found in the cohort study cannot be accounted for by common genetic and environmental factors.</p></sec></abstract><kwd-group><kwd>ASD</kwd><kwd>Autism Spectrum Disorder</kwd><kwd>Effect Measure Modification</kwd><kwd>Interaction</kwd><kwd>Maternal Age</kwd><kwd>Paternal Age</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Lorraine/explor/LrgpV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000158 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000158 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Lorraine
|area= LrgpV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.32. |  |