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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Stereoselective Synthesis of Quaternary Proline Analogues</title><author><name sortKey="Calaza, M Isabel" sort="Calaza, M Isabel" uniqKey="Calaza M" first="M. Isabel" last="Calaza">M. Isabel Calaza</name><affiliation><nlm:aff id="A1">Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza–CSIC, 50009 Zaragoza, Spain, Fax: +34 976 761210</nlm:aff></affiliation></author><author><name sortKey="Cativiela, Carlos" sort="Cativiela, Carlos" uniqKey="Cativiela C" first="Carlos" last="Cativiela">Carlos Cativiela</name><affiliation><nlm:aff id="A1">Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza–CSIC, 50009 Zaragoza, Spain, Fax: +34 976 761210</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19655047</idno><idno type="pmc">2719988</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719988</idno><idno type="RBID">PMC:2719988</idno><idno type="doi">10.1002/ejoc.200800225</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">000115</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000115</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Stereoselective Synthesis of Quaternary Proline Analogues</title><author><name sortKey="Calaza, M Isabel" sort="Calaza, M Isabel" uniqKey="Calaza M" first="M. Isabel" last="Calaza">M. Isabel Calaza</name><affiliation><nlm:aff id="A1">Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza–CSIC, 50009 Zaragoza, Spain, Fax: +34 976 761210</nlm:aff></affiliation></author><author><name sortKey="Cativiela, Carlos" sort="Cativiela, Carlos" uniqKey="Cativiela C" first="Carlos" last="Cativiela">Carlos Cativiela</name><affiliation><nlm:aff id="A1">Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza–CSIC, 50009 Zaragoza, Spain, Fax: +34 976 761210</nlm:aff></affiliation></author></analytic><series><title level="j">European journal of organic chemistry</title><idno type="ISSN">1434-193X</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">This review describes available methods for the diastereoselective and asymmetric synthesis of quaternary prolines. The focus is on the preparation of α-functionalized prolines with the pyrrolidine moiety not embedded in a polycyclic frame. The diverse synthetic approaches are classified according to the bond which is formed to complete the quaternary skeleton.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9805750</journal-id><journal-id journal-id-type="pubmed-jr-id">33377</journal-id><journal-id journal-id-type="nlm-ta">European J Org Chem</journal-id><journal-title>European journal of organic chemistry</journal-title><issn pub-type="ppub">1434-193X</issn></journal-meta><article-meta><article-id pub-id-type="pmid">19655047</article-id><article-id pub-id-type="pmc">2719988</article-id><article-id pub-id-type="doi">10.1002/ejoc.200800225</article-id><article-id pub-id-type="manuscript">NIHMS111640</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Stereoselective Synthesis of Quaternary Proline Analogues</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Calaza</surname><given-names>M. Isabel</given-names></name><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Cativiela</surname><given-names>Carlos</given-names></name><xref ref-type="aff" rid="A1">a</xref><email>cativiela@unizar.es</email></contrib></contrib-group><aff id="A1"><label>a</label>Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza–CSIC, 50009 Zaragoza, Spain, Fax: +34 976 761210</aff><pub-date pub-type="nihms-submitted"><day>28</day><month>4</month><year>2009</year></pub-date><pub-date pub-type="ppub"><year>2008</year></pub-date><pub-date pub-type="pmc-release"><day>3</day><month>8</month><year>2009</year></pub-date><volume>20</volume><fpage>3427</fpage><lpage>3448</lpage><permissions><copyright-statement>© WILEY-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008</copyright-statement><copyright-year>2008</copyright-year></permissions><abstract><p id="P1">This review describes available methods for the diastereoselective and asymmetric synthesis of quaternary prolines. The focus is on the preparation of α-functionalized prolines with the pyrrolidine moiety not embedded in a polycyclic frame. The diverse synthetic approaches are classified according to the bond which is formed to complete the quaternary skeleton.</p></abstract><kwd-group><kwd>α,α-Disubstituted amino acid</kwd><kwd>Constrained amino acid</kwd><kwd>α-Substituted proline</kwd><kwd>Diastereoselectivity</kwd><kwd>Enantioselectivity</kwd></kwd-group><contract-num rid="CO1">N01 CO012400
||CO</contract-num><contract-sponsor id="CO1">Office of the Director : NCI</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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