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Lipophilic phthalocyanines for their potential interest in photodynamic therapy: synthesis and photo-physical properties

Identifieur interne : 000693 ( Hal/Curation ); précédent : 000692; suivant : 000694

Lipophilic phthalocyanines for their potential interest in photodynamic therapy: synthesis and photo-physical properties

Auteurs : Albert Moussaron [France] ; Philippe Arnoux [France] ; Régis Vanderesse [France] ; Estelle Sibille [France] ; Patrick Chaimbault [France] ; Céline Frochot [France]

Source :

RBID : Hal:hal-01278786

Abstract

Several phthalocyanines with different peripheral substituents were prepared and characterized by MALDI-TOF, H-1 NMR, UV-vis, fluorescence, and singlet oxygen quantum yields and retention time in HPLC normal phase. Zinc was used as a central metal ion to increase the photodynamic therapy efficiency. Phthalonitrile or 4-nitro phthalonitriles were used as starting materials. The influence of lipophilicity on the photophysical and photochemical properties was evaluated.

Url:
DOI: 10.1016/j.tet.2013.09.035

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Hal:hal-01278786

Le document en format XML

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