Lipophilic phthalocyanines for their potential interest in photodynamic therapy: synthesis and photo-physical properties
Identifieur interne : 000693 ( Hal/Curation ); précédent : 000692; suivant : 000694Lipophilic phthalocyanines for their potential interest in photodynamic therapy: synthesis and photo-physical properties
Auteurs : Albert Moussaron [France] ; Philippe Arnoux [France] ; Régis Vanderesse [France] ; Estelle Sibille [France] ; Patrick Chaimbault [France] ; Céline Frochot [France]Source :
- Tetrahedron [ 0040-4020 ] ; 2013-11.
Abstract
Several phthalocyanines with different peripheral substituents were prepared and characterized by MALDI-TOF, H-1 NMR, UV-vis, fluorescence, and singlet oxygen quantum yields and retention time in HPLC normal phase. Zinc was used as a central metal ion to increase the photodynamic therapy efficiency. Phthalonitrile or 4-nitro phthalonitriles were used as starting materials. The influence of lipophilicity on the photophysical and photochemical properties was evaluated.
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DOI: 10.1016/j.tet.2013.09.035
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