LrgpV1, Hal, Corpus, bibRecord, 000626

Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method

Identifieur interne : 000626 ( Hal/Corpus ); précédent : 000625; suivant : 000627

Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method

Auteurs : Amal Tita ; Diana Campos ; Véronique Sadtler ; Philippe Marchal ; Véronique Falk

Source :

Powder Technology [ 0032-5910 ] ; 2012-11.

RBID : Hal:hal-00778448

English descriptors

mix :
- GLASS-TRANSITION, Liquid binders, Sugars, TABLETS, Tensile strength, WATER, Water activity, Wet compression.

Abstract

In this work, we aimed at studying formulation and design of powders by modified wet compression method. In order to focus only on the role of the liquid binder in the mechanical cohesion of compacts, glass beads were used as model particles because they do not deform or fragment at the compression pressure used (35kN). The three different binders studied were sugars: fructose, glucose and saccharose, used as solutions. Therefore, compacts were stored at controlled conditions until reaching water activity equilibrium at a fixed temperature of 25 degrees C. Then, the tensile strength of the compacts was determined using a Brazilian test. It was found to be dependent on the water activity. Critical values of Aw were measured (A(w) = 0.23 for the fructose, A(w) = 0.33 for the glucose, and A(w) = 0.44 for the saccharose), beyond which the glass transition phenomenon of the sugars appeared, and resulted in a sharp drop in the mechanical strength of the compacts. The classification of the sugars according to their respective glass transition temperature (Tg(fructose) < Tg(glucose), < Tg(saccharose)) permitted to confirm the role of the glass transition of the sugars as binders in the mechanical resistance of the compacts. Finally, sorption isotherms of the sugars coupled to the tensile strength results showed that the main parameter for predicting mechanical strength of the compact was the amount of sorbed water by the sugar, regardless to his nature.

Url:

https://hal.archives-ouvertes.fr/hal-00778448

DOI: 10.1016/j.powtec.2012.06.058

Links to Exploration step

Hal:hal-00778448

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method</title>
<author><name sortKey="Tita, Amal" sort="Tita, Amal" uniqKey="Tita A" first="Amal" last="Tita">Amal Tita</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Campos, Diana" sort="Campos, Diana" uniqKey="Campos D" first="Diana" last="Campos">Diana Campos</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Sadtler, Veronique" sort="Sadtler, Veronique" uniqKey="Sadtler V" first="Véronique" last="Sadtler">Véronique Sadtler</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Marchal, Philippe" sort="Marchal, Philippe" uniqKey="Marchal P" first="Philippe" last="Marchal">Philippe Marchal</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Falk, Veronique" sort="Falk, Veronique" uniqKey="Falk V" first="Véronique" last="Falk">Véronique Falk</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-00778448</idno>
<idno type="halId">hal-00778448</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-00778448</idno>
<idno type="url">https://hal.archives-ouvertes.fr/hal-00778448</idno>
<idno type="doi">10.1016/j.powtec.2012.06.058</idno>
<date when="2012-11">2012-11</date>
<idno type="wicri:Area/Hal/Corpus">000626</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method</title>
<author><name sortKey="Tita, Amal" sort="Tita, Amal" uniqKey="Tita A" first="Amal" last="Tita">Amal Tita</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Campos, Diana" sort="Campos, Diana" uniqKey="Campos D" first="Diana" last="Campos">Diana Campos</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Sadtler, Veronique" sort="Sadtler, Veronique" uniqKey="Sadtler V" first="Véronique" last="Sadtler">Véronique Sadtler</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Marchal, Philippe" sort="Marchal, Philippe" uniqKey="Marchal P" first="Philippe" last="Marchal">Philippe Marchal</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Falk, Veronique" sort="Falk, Veronique" uniqKey="Falk V" first="Véronique" last="Falk">Véronique Falk</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-211875" status="VALID"><idno type="IdRef">153068876</idno>
<idno type="RNSR">201320573K</idno>
<idno type="IdUnivLorraine">[UL]RQC--</idno>
<orgName>Laboratoire Réactions et Génie des Procédés</orgName>
<orgName type="acronym">LRGP</orgName>
<date type="start">2013-01-01</date>
<desc><address><addrLine>Université de Lorraine - ENSIC, 1 rue de Grandville BP 20451, 54001 Nancy Cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://lrgp.univ-lorraine.fr/</ref>
</desc>
<listRelation><relation active="#struct-413289" type="direct"></relation>
<relation name="UMR7274" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"><idno type="IdRef">157040569</idno>
<idno type="IdUnivLorraine">[UL]100--</idno>
<orgName>Université de Lorraine</orgName>
<orgName type="acronym">UL</orgName>
<date type="start">2012-01-01</date>
<desc><address><addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-lorraine.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7274" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"><idno type="ISNI">0000000122597504</idno>
<idno type="IdRef">02636817X</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc><address><country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1016/j.powtec.2012.06.058</idno>
<series><title level="j">Powder Technology</title>
<idno type="ISSN">0032-5910</idno>
<imprint><date type="datePub">2012-11</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>GLASS-TRANSITION</term>
<term>Liquid binders</term>
<term>Sugars</term>
<term>TABLETS</term>
<term>Tensile strength</term>
<term>WATER</term>
<term>Water activity</term>
<term>Wet compression</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">In this work, we aimed at studying formulation and design of powders by modified wet compression method. In order to focus only on the role of the liquid binder in the mechanical cohesion of compacts, glass beads were used as model particles because they do not deform or fragment at the compression pressure used (35kN). The three different binders studied were sugars: fructose, glucose and saccharose, used as solutions. Therefore, compacts were stored at controlled conditions until reaching water activity equilibrium at a fixed temperature of 25 degrees C. Then, the tensile strength of the compacts was determined using a Brazilian test. It was found to be dependent on the water activity. Critical values of Aw were measured (A(w) = 0.23 for the fructose, A(w) = 0.33 for the glucose, and A(w) = 0.44 for the saccharose), beyond which the glass transition phenomenon of the sugars appeared, and resulted in a sharp drop in the mechanical strength of the compacts. The classification of the sugars according to their respective glass transition temperature (Tg(fructose) < Tg(glucose), < Tg(saccharose)) permitted to confirm the role of the glass transition of the sugars as binders in the mechanical resistance of the compacts. Finally, sorption isotherms of the sugars coupled to the tensile strength results showed that the main parameter for predicting mechanical strength of the compact was the amount of sorbed water by the sugar, regardless to his nature.</div>
</front>
</TEI>
<hal api="V3"><titleStmt><title xml:lang="en">Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method</title>
<author role="aut"><persName><forename type="first">Amal</forename>
<surname>Tita</surname>
</persName>
<email></email>
<idno type="halauthor">807628</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="aut"><persName><forename type="first">Diana</forename>
<surname>Campos</surname>
</persName>
<email></email>
<idno type="halauthor">807629</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="aut"><persName><forename type="first">Véronique</forename>
<surname>Sadtler</surname>
</persName>
<email></email>
<idno type="halauthor">807630</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="aut"><persName><forename type="first">Philippe</forename>
<surname>Marchal</surname>
</persName>
<email></email>
<idno type="halauthor">57749</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="crp"><persName><forename type="first">Véronique</forename>
<surname>Falk</surname>
</persName>
<email>veronique.falk@univ-lorraine.fr</email>
<idno type="halauthor">807631</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<editor role="depositor"><persName><forename>Gabriel</forename>
<surname>Wild</surname>
</persName>
<email>gabriel.wild@univ-lorraine.fr</email>
</editor>
</titleStmt>
<editionStmt><edition n="v1" type="current"><date type="whenSubmitted">2013-01-20 14:21:33</date>
<date type="whenWritten">2012</date>
<date type="whenModified">2016-05-10 16:53:34</date>
<date type="whenReleased">2013-01-20 14:21:33</date>
<date type="whenProduced">2012-11</date>
</edition>
<respStmt><resp>contributor</resp>
<name key="179637"><persName><forename>Gabriel</forename>
<surname>Wild</surname>
</persName>
<email>gabriel.wild@univ-lorraine.fr</email>
</name>
</respStmt>
</editionStmt>
<publicationStmt><distributor>CCSD</distributor>
<idno type="halId">hal-00778448</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-00778448</idno>
<idno type="halBibtex">tita:hal-00778448</idno>
<idno type="halRefHtml">Powder Technology, Elsevier, 2012, 230, pp.86-92. <10.1016/j.powtec.2012.06.058></idno>
<idno type="halRef">Powder Technology, Elsevier, 2012, 230, pp.86-92. <10.1016/j.powtec.2012.06.058></idno>
</publicationStmt>
<seriesStmt><idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
<idno type="stamp" n="UNIV-LORRAINE">Université de Lorraine</idno>
<idno type="stamp" n="LRGP-UL">LRGP</idno>
</seriesStmt>
<notesStmt><note type="audience" n="2">International</note>
<note type="popular" n="0">No</note>
<note type="peer" n="1">Yes</note>
</notesStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method</title>
<author role="aut"><persName><forename type="first">Amal</forename>
<surname>Tita</surname>
</persName>
<idno type="halAuthorId">807628</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="aut"><persName><forename type="first">Diana</forename>
<surname>Campos</surname>
</persName>
<idno type="halAuthorId">807629</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="aut"><persName><forename type="first">Véronique</forename>
<surname>Sadtler</surname>
</persName>
<idno type="halAuthorId">807630</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="aut"><persName><forename type="first">Philippe</forename>
<surname>Marchal</surname>
</persName>
<idno type="halAuthorId">57749</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
<author role="crp"><persName><forename type="first">Véronique</forename>
<surname>Falk</surname>
</persName>
<email>veronique.falk@univ-lorraine.fr</email>
<idno type="halAuthorId">807631</idno>
<affiliation ref="#struct-211875"></affiliation>
</author>
</analytic>
<monogr><idno type="halJournalId" status="VALID">18151</idno>
<idno type="issn">0032-5910</idno>
<title level="j">Powder Technology</title>
<imprint><publisher>Elsevier</publisher>
<biblScope unit="volume">230</biblScope>
<biblScope unit="pp">86-92</biblScope>
<date type="datePub">2012-11</date>
</imprint>
</monogr>
<idno type="doi">10.1016/j.powtec.2012.06.058</idno>
</biblStruct>
</sourceDesc>
<profileDesc><langUsage><language ident="en">English</language>
</langUsage>
<textClass><keywords scheme="author"><term xml:lang="en">Wet compression</term>
<term xml:lang="en">Liquid binders</term>
<term xml:lang="en">Sugars</term>
<term xml:lang="en">Water activity</term>
<term xml:lang="en">Tensile strength</term>
<term xml:lang="en">GLASS-TRANSITION</term>
<term xml:lang="en">TABLETS</term>
<term xml:lang="en">WATER</term>
</keywords>
<classCode scheme="halDomain" n="spi.gproc">Engineering Sciences [physics]/Chemical and Process Engineering</classCode>
<classCode scheme="halTypology" n="ART">Journal articles</classCode>
</textClass>
<abstract xml:lang="en">In this work, we aimed at studying formulation and design of powders by modified wet compression method. In order to focus only on the role of the liquid binder in the mechanical cohesion of compacts, glass beads were used as model particles because they do not deform or fragment at the compression pressure used (35kN). The three different binders studied were sugars: fructose, glucose and saccharose, used as solutions. Therefore, compacts were stored at controlled conditions until reaching water activity equilibrium at a fixed temperature of 25 degrees C. Then, the tensile strength of the compacts was determined using a Brazilian test. It was found to be dependent on the water activity. Critical values of Aw were measured (A(w) = 0.23 for the fructose, A(w) = 0.33 for the glucose, and A(w) = 0.44 for the saccharose), beyond which the glass transition phenomenon of the sugars appeared, and resulted in a sharp drop in the mechanical strength of the compacts. The classification of the sugars according to their respective glass transition temperature (Tg(fructose) < Tg(glucose), < Tg(saccharose)) permitted to confirm the role of the glass transition of the sugars as binders in the mechanical resistance of the compacts. Finally, sorption isotherms of the sugars coupled to the tensile strength results showed that the main parameter for predicting mechanical strength of the compact was the amount of sorbed water by the sugar, regardless to his nature.</abstract>
</profileDesc>
</hal>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Lorraine/explor/LrgpV1/Data/Hal/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000626 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Hal/Corpus/biblio.hfd -nk 000626 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Lorraine
   |area=    LrgpV1
   |flux=    Hal
   |étape=   Corpus
   |type=    RBID
   |clé=     Hal:hal-00778448
   |texte=   Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method
}}

This area was generated with Dilib version V0.6.32.
Data generation: Sat Nov 11 15:47:48 2017. Site generation: Wed Mar 6 23:31:34 2024

	Serveur d'exploration sur le LRGP
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le LRGP

Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method

Influence of the binder on the mechanical strength of compacts prepared by modified wet compression method

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri