Biphasic solid and liquid gastric emptying in normal controls and diabetics using continuous acquisition in LAO view.
Identifieur interne : 005077 ( Main/Exploration ); précédent : 005076; suivant : 005078Biphasic solid and liquid gastric emptying in normal controls and diabetics using continuous acquisition in LAO view.
Auteurs : RBID : pubmed:1563318English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Chronic Disease, Diabetes Mellitus, Type 1 (physiopathology), Diabetes Mellitus, Type 1 (radionuclide imaging), Female, Gamma Cameras, Gastric Emptying (physiology), Humans, Indium Radioisotopes (diagnostic use), Male, Middle Aged, Pentetic Acid (diagnostic use), Stomach (physiopathology), Stomach (radionuclide imaging), Technetium (diagnostic use).
- MESH :
- chemical , diagnostic use : Indium Radioisotopes, Pentetic Acid, Technetium.
- physiology : Gastric Emptying.
- physiopathology : Diabetes Mellitus, Type 1, Stomach.
- radionuclide imaging : Diabetes Mellitus, Type 1, Stomach.
- Adolescent, Adult, Aged, Chronic Disease, Female, Gamma Cameras, Humans, Male, Middle Aged.
Abstract
The purpose of this study was to investigate the various phases of gastric emptying using a dual-isotope liquid-solid meal ([99mTc]SC egg sandwich and [111In]DPTA in water) and continuous acquisition in the left anterior oblique view. The study groups consisted of 10 normal controls and 20 diabetics with symptoms suggestive of diabetic gastroparesis. Solid-phase emptying in both groups almost always had a lag phase followed by linear emptying. Liquid-phase emptying was biexponential in 4/10 normals and 12/20 diabetics, with a short early rapid emptying rate (mean T1/2 = 48 min in normals and 79 min in diabetics). Solid emptying was delayed in 10, normal in eight, and rapid in two diabetics. Liquid emptying was delayed in 9/10 diabetics who had delayed solid emptying. Diabetics as a group had a significantly delayed solid lag phase (P less than 0.025), rate of emptying (P less than 0.05) and percent emptying at 90 min (P less than 0.025) compared to normal controls. Diabetic liquid emptying was also significantly delayed (P less than 0.025). The second component of liquid emptying strongly correlated with the solid rate of emptying (r = 0.826 in normals and 0.855 in diabetics). Continuous acquisition of gastric emptying studies in the LAO view has allowed us to better define the various phases of solid and liquid gastric emptying.
PubMed: 1563318
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Biphasic solid and liquid gastric emptying in normal controls and diabetics using continuous acquisition in LAO view.</title><author><name sortKey="Ziessman, H A" uniqKey="Ziessman H">H A Ziessman</name><affiliation><nlm:affiliation>Department of Radiology, Georgetown University Hospital, Washington, D.C. 20007.</nlm:affiliation><wicri:noCountry code="subField">D.C.</wicri:noCountry></affiliation></author><author><name sortKey="Fahey, F H" uniqKey="Fahey F">F H Fahey</name></author><author><name sortKey="Collen, M J" uniqKey="Collen M">M J Collen</name></author></titleStmt><publicationStmt><date when="1992">1992</date><idno type="RBID">pubmed:1563318</idno><idno type="pmid">1563318</idno><idno type="wicri:Area/Main/Corpus">005310</idno><idno type="wicri:Area/Main/Curation">005310</idno><idno type="wicri:Area/Main/Exploration">005077</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Chronic Disease</term><term>Diabetes Mellitus, Type 1 (physiopathology)</term><term>Diabetes Mellitus, Type 1 (radionuclide imaging)</term><term>Female</term><term>Gamma Cameras</term><term>Gastric Emptying (physiology)</term><term>Humans</term><term>Indium Radioisotopes (diagnostic use)</term><term>Male</term><term>Middle Aged</term><term>Pentetic Acid (diagnostic use)</term><term>Stomach (physiopathology)</term><term>Stomach (radionuclide imaging)</term><term>Technetium (diagnostic use)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Indium Radioisotopes</term><term>Pentetic Acid</term><term>Technetium</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Gastric Emptying</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Diabetes Mellitus, Type 1</term><term>Stomach</term></keywords><keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Diabetes Mellitus, Type 1</term><term>Stomach</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Chronic Disease</term><term>Female</term><term>Gamma Cameras</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this study was to investigate the various phases of gastric emptying using a dual-isotope liquid-solid meal ([99mTc]SC egg sandwich and [111In]DPTA in water) and continuous acquisition in the left anterior oblique view. The study groups consisted of 10 normal controls and 20 diabetics with symptoms suggestive of diabetic gastroparesis. Solid-phase emptying in both groups almost always had a lag phase followed by linear emptying. Liquid-phase emptying was biexponential in 4/10 normals and 12/20 diabetics, with a short early rapid emptying rate (mean T1/2 = 48 min in normals and 79 min in diabetics). Solid emptying was delayed in 10, normal in eight, and rapid in two diabetics. Liquid emptying was delayed in 9/10 diabetics who had delayed solid emptying. Diabetics as a group had a significantly delayed solid lag phase (P less than 0.025), rate of emptying (P less than 0.05) and percent emptying at 90 min (P less than 0.025) compared to normal controls. Diabetic liquid emptying was also significantly delayed (P less than 0.025). The second component of liquid emptying strongly correlated with the solid rate of emptying (r = 0.826 in normals and 0.855 in diabetics). Continuous acquisition of gastric emptying studies in the LAO view has allowed us to better define the various phases of solid and liquid gastric emptying.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">1563318</PMID><DateCreated><Year>1992</Year><Month>05</Month><Day>20</Day></DateCreated><DateCompleted><Year>1992</Year><Month>05</Month><Day>20</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0163-2116</ISSN><JournalIssue CitedMedium="Print"><Volume>37</Volume><Issue>5</Issue><PubDate><Year>1992</Year><Month>May</Month></PubDate></JournalIssue><Title>Digestive diseases and sciences</Title><ISOAbbreviation>Dig. Dis. Sci.</ISOAbbreviation></Journal><ArticleTitle>Biphasic solid and liquid gastric emptying in normal controls and diabetics using continuous acquisition in LAO view.</ArticleTitle><Pagination><MedlinePgn>744-50</MedlinePgn></Pagination><Abstract><AbstractText>The purpose of this study was to investigate the various phases of gastric emptying using a dual-isotope liquid-solid meal ([99mTc]SC egg sandwich and [111In]DPTA in water) and continuous acquisition in the left anterior oblique view. The study groups consisted of 10 normal controls and 20 diabetics with symptoms suggestive of diabetic gastroparesis. Solid-phase emptying in both groups almost always had a lag phase followed by linear emptying. Liquid-phase emptying was biexponential in 4/10 normals and 12/20 diabetics, with a short early rapid emptying rate (mean T1/2 = 48 min in normals and 79 min in diabetics). Solid emptying was delayed in 10, normal in eight, and rapid in two diabetics. Liquid emptying was delayed in 9/10 diabetics who had delayed solid emptying. Diabetics as a group had a significantly delayed solid lag phase (P less than 0.025), rate of emptying (P less than 0.05) and percent emptying at 90 min (P less than 0.025) compared to normal controls. Diabetic liquid emptying was also significantly delayed (P less than 0.025). The second component of liquid emptying strongly correlated with the solid rate of emptying (r = 0.826 in normals and 0.855 in diabetics). Continuous acquisition of gastric emptying studies in the LAO view has allowed us to better define the various phases of solid and liquid gastric emptying.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ziessman</LastName><ForeName>H A</ForeName><Initials>HA</Initials><Affiliation>Department of Radiology, Georgetown University Hospital, Washington, D.C. 20007.</Affiliation></Author><Author ValidYN="Y"><LastName>Fahey</LastName><ForeName>F H</ForeName><Initials>FH</Initials></Author><Author ValidYN="Y"><LastName>Collen</LastName><ForeName>M J</ForeName><Initials>MJ</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Comparative Study</PublicationType><PublicationType>Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>UNITED STATES</Country><MedlineTA>Dig Dis Sci</MedlineTA><NlmUniqueID>7902782</NlmUniqueID><ISSNLinking>0163-2116</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Indium Radioisotopes</NameOfSubstance></Chemical><Chemical><RegistryNumber>7440-26-8</RegistryNumber><NameOfSubstance>Technetium</NameOfSubstance></Chemical><Chemical><RegistryNumber>7A314HQM0I</RegistryNumber><NameOfSubstance>Pentetic Acid</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Chronic Disease</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Diabetes Mellitus, Type 1</DescriptorName><QualifierName MajorTopicYN="Y">physiopathology</QualifierName><QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Gamma Cameras</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Gastric Emptying</DescriptorName><QualifierName MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Pentetic Acid</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Stomach</DescriptorName><QualifierName MajorTopicYN="N">physiopathology</QualifierName><QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Technetium</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1992</Year><Month>5</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1992</Year><Month>5</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1992</Year><Month>5</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">1563318</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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