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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cervical Cancer in Ethiopia: Survival of 1,059 Patients Who Received Oncologic Therapy</title><author><name sortKey="Kantelhardt, Eva Johanna" sort="Kantelhardt, Eva Johanna" uniqKey="Kantelhardt E" first="Eva Johanna" last="Kantelhardt">Eva Johanna Kantelhardt</name></author><author><name sortKey="Moelle, Ulrike" sort="Moelle, Ulrike" uniqKey="Moelle U" first="Ulrike" last="Moelle">Ulrike Moelle</name></author><author><name sortKey="Begoihn, Matthias" sort="Begoihn, Matthias" uniqKey="Begoihn M" first="Matthias" last="Begoihn">Matthias Begoihn</name></author><author><name sortKey="Addissie, Adamu" sort="Addissie, Adamu" uniqKey="Addissie A" first="Adamu" last="Addissie">Adamu Addissie</name></author><author><name sortKey="Trocchi, Pietro" sort="Trocchi, Pietro" uniqKey="Trocchi P" first="Pietro" last="Trocchi">Pietro Trocchi</name></author><author><name sortKey="Yonas, Bekuretsion" sort="Yonas, Bekuretsion" uniqKey="Yonas B" first="Bekuretsion" last="Yonas">Bekuretsion Yonas</name></author><author><name sortKey="Hezkiel, Petros" sort="Hezkiel, Petros" uniqKey="Hezkiel P" first="Petros" last="Hezkiel">Petros Hezkiel</name></author><author><name sortKey="Stang, Andreas" sort="Stang, Andreas" uniqKey="Stang A" first="Andreas" last="Stang">Andreas Stang</name></author><author><name sortKey="Thomssen, Christoph" sort="Thomssen, Christoph" uniqKey="Thomssen C" first="Christoph" last="Thomssen">Christoph Thomssen</name></author><author><name sortKey="Vordermark, Dirk" sort="Vordermark, Dirk" uniqKey="Vordermark D" first="Dirk" last="Vordermark">Dirk Vordermark</name></author><author><name sortKey="Gemechu, Tufa" sort="Gemechu, Tufa" uniqKey="Gemechu T" first="Tufa" last="Gemechu">Tufa Gemechu</name></author><author><name sortKey="Gebrehiwot, Yirgu" sort="Gebrehiwot, Yirgu" uniqKey="Gebrehiwot Y" first="Yirgu" last="Gebrehiwot">Yirgu Gebrehiwot</name></author><author><name sortKey="Wondemagegnehu, Tigeneh" sort="Wondemagegnehu, Tigeneh" uniqKey="Wondemagegnehu T" first="Tigeneh" last="Wondemagegnehu">Tigeneh Wondemagegnehu</name></author><author><name sortKey="Aynalem, Abreha" sort="Aynalem, Abreha" uniqKey="Aynalem A" first="Abreha" last="Aynalem">Abreha Aynalem</name></author><author><name sortKey="Mathewos, Assefa" sort="Mathewos, Assefa" uniqKey="Mathewos A" first="Assefa" last="Mathewos">Assefa Mathewos</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24951611</idno><idno type="pmc">4077439</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077439</idno><idno type="RBID">PMC:4077439</idno><idno type="doi">10.1634/theoncologist.2013-0326</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000326</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000326</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cervical Cancer in Ethiopia: Survival of 1,059 Patients Who Received Oncologic Therapy</title><author><name sortKey="Kantelhardt, Eva Johanna" sort="Kantelhardt, Eva Johanna" uniqKey="Kantelhardt E" first="Eva Johanna" last="Kantelhardt">Eva Johanna Kantelhardt</name></author><author><name sortKey="Moelle, Ulrike" sort="Moelle, Ulrike" uniqKey="Moelle U" first="Ulrike" last="Moelle">Ulrike Moelle</name></author><author><name sortKey="Begoihn, Matthias" sort="Begoihn, Matthias" uniqKey="Begoihn M" first="Matthias" last="Begoihn">Matthias Begoihn</name></author><author><name sortKey="Addissie, Adamu" sort="Addissie, Adamu" uniqKey="Addissie A" first="Adamu" last="Addissie">Adamu Addissie</name></author><author><name sortKey="Trocchi, Pietro" sort="Trocchi, Pietro" uniqKey="Trocchi P" first="Pietro" last="Trocchi">Pietro Trocchi</name></author><author><name sortKey="Yonas, Bekuretsion" sort="Yonas, Bekuretsion" uniqKey="Yonas B" first="Bekuretsion" last="Yonas">Bekuretsion Yonas</name></author><author><name sortKey="Hezkiel, Petros" sort="Hezkiel, Petros" uniqKey="Hezkiel P" first="Petros" last="Hezkiel">Petros Hezkiel</name></author><author><name sortKey="Stang, Andreas" sort="Stang, Andreas" uniqKey="Stang A" first="Andreas" last="Stang">Andreas Stang</name></author><author><name sortKey="Thomssen, Christoph" sort="Thomssen, Christoph" uniqKey="Thomssen C" first="Christoph" last="Thomssen">Christoph Thomssen</name></author><author><name sortKey="Vordermark, Dirk" sort="Vordermark, Dirk" uniqKey="Vordermark D" first="Dirk" last="Vordermark">Dirk Vordermark</name></author><author><name sortKey="Gemechu, Tufa" sort="Gemechu, Tufa" uniqKey="Gemechu T" first="Tufa" last="Gemechu">Tufa Gemechu</name></author><author><name sortKey="Gebrehiwot, Yirgu" sort="Gebrehiwot, Yirgu" uniqKey="Gebrehiwot Y" first="Yirgu" last="Gebrehiwot">Yirgu Gebrehiwot</name></author><author><name sortKey="Wondemagegnehu, Tigeneh" sort="Wondemagegnehu, Tigeneh" uniqKey="Wondemagegnehu T" first="Tigeneh" last="Wondemagegnehu">Tigeneh Wondemagegnehu</name></author><author><name sortKey="Aynalem, Abreha" sort="Aynalem, Abreha" uniqKey="Aynalem A" first="Abreha" last="Aynalem">Abreha Aynalem</name></author><author><name sortKey="Mathewos, Assefa" sort="Mathewos, Assefa" uniqKey="Mathewos A" first="Assefa" last="Mathewos">Assefa Mathewos</name></author></analytic><series><title level="j">The Oncologist</title><idno type="ISSN">1083-7159</idno><idno type="eISSN">1549-490X</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The primary objective was to evaluate outcome of consecutive cervical cancer patients treated over 4 years at the only radiotherapy center in Ethiopia. Two-year overall survival was 73.6%. Promoting early detection and increasing ... Increasing the capacity for external-beam radiation as well as options for brachytherapy would facilitate treatment with curative intention.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Oncologist</journal-id><journal-id journal-id-type="iso-abbrev">Oncologist</journal-id><journal-id journal-id-type="pmc">oncologist</journal-id><journal-id journal-id-type="hwp">theoncologist</journal-id><journal-id journal-id-type="publisher-id">The Oncologist</journal-id><journal-title-group><journal-title>The Oncologist</journal-title></journal-title-group><issn pub-type="ppub">1083-7159</issn><issn pub-type="epub">1549-490X</issn><publisher><publisher-name>AlphaMed Press</publisher-name><publisher-loc>Durham, NC, USA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24951611</article-id><article-id pub-id-type="pmc">4077439</article-id><article-id pub-id-type="publisher-id">T13326</article-id><article-id pub-id-type="doi">10.1634/theoncologist.2013-0326</article-id><article-categories><subj-group subj-group-type="heading"><subject>Global Health and Cancer</subject></subj-group></article-categories><title-group><article-title>Cervical Cancer in Ethiopia: Survival of 1,059 Patients Who Received Oncologic Therapy</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Kantelhardt</surname><given-names>Eva Johanna</given-names></name><xref ref-type="aff" rid="aff1"><sup>a</sup></xref><xref ref-type="aff" rid="aff2"><sup>b</sup></xref></contrib><contrib contrib-type="author"><name><surname>Moelle</surname><given-names>Ulrike</given-names></name><xref ref-type="aff" rid="aff1"><sup>a</sup></xref></contrib><contrib contrib-type="author"><name><surname>Begoihn</surname><given-names>Matthias</given-names></name><xref ref-type="aff" rid="aff1"><sup>a</sup></xref></contrib><contrib contrib-type="author"><name><surname>Addissie</surname><given-names>Adamu</given-names></name><xref ref-type="aff" rid="aff3"><sup>c</sup></xref></contrib><contrib contrib-type="author"><name><surname>Trocchi</surname><given-names>Pietro</given-names></name><xref ref-type="aff" rid="aff2"><sup>b</sup></xref></contrib><contrib contrib-type="author"><name><surname>Yonas</surname><given-names>Bekuretsion</given-names></name><xref ref-type="aff" rid="aff4"><sup>d</sup></xref></contrib><contrib contrib-type="author"><name><surname>Hezkiel</surname><given-names>Petros</given-names></name><xref ref-type="aff" rid="aff5"><sup>e</sup></xref></contrib><contrib contrib-type="author"><name><surname>Stang</surname><given-names>Andreas</given-names></name><xref ref-type="aff" rid="aff2"><sup>b</sup></xref><xref ref-type="aff" rid="aff7"><sup>g</sup></xref></contrib><contrib contrib-type="author"><name><surname>Thomssen</surname><given-names>Christoph</given-names></name><xref ref-type="aff" rid="aff1"><sup>a</sup></xref></contrib><contrib contrib-type="author"><name><surname>Vordermark</surname><given-names>Dirk</given-names></name><xref ref-type="aff" rid="aff3"><sup>c</sup></xref></contrib><contrib contrib-type="author"><name><surname>Gemechu</surname><given-names>Tufa</given-names></name><xref ref-type="aff" rid="aff4"><sup>d</sup></xref></contrib><contrib contrib-type="author"><name><surname>Gebrehiwot</surname><given-names>Yirgu</given-names></name><xref ref-type="aff" rid="aff5"><sup>e</sup></xref></contrib><contrib contrib-type="author"><name><surname>Wondemagegnehu</surname><given-names>Tigeneh</given-names></name><xref ref-type="aff" rid="aff6"><sup>f</sup></xref></contrib><contrib contrib-type="author"><name><surname>Aynalem</surname><given-names>Abreha</given-names></name><xref ref-type="aff" rid="aff6"><sup>f</sup></xref></contrib><contrib contrib-type="author"><name><surname>Mathewos</surname><given-names>Assefa</given-names></name><xref ref-type="aff" rid="aff6"><sup>f</sup></xref></contrib><aff><target id="aff1" target-type="aff"><sup>a</sup></target>Department of Gynaecology and<target id="aff2" target-type="aff"><sup>b</sup></target>Institute of Clinical Epidemiology, Martin Luther University, Halle an der Saale, Germany;<target id="aff3" target-type="aff"><sup>c</sup></target>School of Public Health, Departments of<target id="aff4" target-type="aff"><sup>d</sup></target>Pathology and<target id="aff5" target-type="aff"><sup>e</sup></target>Gynaecology, and<target id="aff6" target-type="aff"><sup>f</sup></target>Radiotherapy Center, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia;<target id="aff7" target-type="aff"><sup>g</sup></target>Department of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts, USA</aff></contrib-group><author-notes><corresp id="cor1">Correspondence: Eva Johanna Kantelhardt, M.D., Department of Gynaecology and Institute of Clinical Epidemiology, Ernst-Grube Strasse 40, 06097 Halle an der Saale, Germany. Telephone: <phone>49-345-557-1847</phone>; E-Mail: <email>eva.kantelhardt@medizin.uni-halle.de</email></corresp><fn id="afn1" fn-type="conflict"><p>Disclosures of potential conflicts of interest may be found at the end of this article.</p></fn></author-notes><pub-date pub-type="ppub"><month>7</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>20</day><month>6</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>7</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 12 months and 0 days and was based on the
<volume>19</volume><issue>7</issue><fpage>727</fpage><lpage>734</lpage><history><date date-type="received"><day>20</day><month>8</month><year>2013</year></date><date date-type="accepted"><day>08</day><month>5</month><year>2014</year></date></history><permissions><copyright-statement>©AlphaMed Press</copyright-statement><copyright-year>2014</copyright-year></permissions><self-uri xlink:title="pdf" xlink:type="simple" xlink:href="theoncologist_13326.pdf"></self-uri><abstract abstract-type="precis"><p>The primary objective was to evaluate outcome of consecutive cervical cancer patients treated over 4 years at the only radiotherapy center in Ethiopia. Two-year overall survival was 73.6%. Promoting early detection and increasing ... Increasing the capacity for external-beam radiation as well as options for brachytherapy would facilitate treatment with curative intention.</p></abstract><abstract><sec><title>Background.</title><p>Almost 500,000 women are newly diagnosed with cervical cancer (CC) every year, the majority from developing countries. There is little information on the survival of these patients. Our primary objective was to evaluate consecutive CC patients presenting over 4 years at the only radiotherapy center in Ethiopia.</p></sec><sec><title>Methods.</title><p>All patients with CC from September 2008 to September 2012 who received radiotherapy and/or surgery were included (without brachytherapy). Vital status was obtained through telephone contact or patient cards.</p></sec><sec><title>Results.</title><p>Of 2,300 CC patients, 1,059 patients with standardized treatment were included. At the end of the study, 249 patients had died; surviving patients had a median follow-up of 16.5 months; the 10% and 90% percentiles were 3.0 and 32.7 months, respectively. Mean age was 49 years (21–91 years). The majority of patients presented with International Federation of Gynecology and Obstetrics stage IIb–IIIa (46.7%). Because of progression during the waiting time (median 3.8 months), this proportion declined to 19.3% at the beginning of radiotherapy. The 1- and 2-year overall survival probabilities were 90.4% and 73.6%. If assuming a worst-case scenario (i.e., if all patients not available for follow-up after 6 months had died), the 2-year survival probability would be 45.4%.</p></sec><sec><title>Conclusion.</title><p>This study gives a thorough 4-year overview of treated patients with CC in Ethiopia. Given the limited treatment availability, a relatively high proportion of patients survived 2 years. More prevention and early detection at all levels of the health care system are needed. Increasing the capacity for external-beam radiation as well as options for brachytherapy would facilitate treatment with curative intention.</p></sec></abstract><kwd-group><kwd>Uterine cervical neoplasms</kwd><kwd>Africa</kwd><kwd>Ethiopia</kwd><kwd>Survival</kwd><kwd>Prognosis</kwd></kwd-group><counts><page-count count="8"></page-count></counts><custom-meta-group><custom-meta><meta-name> DJS Export </meta-name><meta-value>v1</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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