Role of cultivation media in the development of yeast strains for large scale industrial use
Identifieur interne : 000362 ( Pmc/Checkpoint ); précédent : 000361; suivant : 000363Role of cultivation media in the development of yeast strains for large scale industrial use
Auteurs : B Rbel Hahn-H Gerdal [Suède] ; Kaisa Karhumaa [Suède] ; Christer U. Larsson [Suède] ; Marie Gorwa-Grauslund [Suède] ; Johann Görgens [Afrique du Sud] ; Willem H. Van ZylSource :
- Microbial Cell Factories [ 1475-2859 ] ; 2005.
Abstract
The composition of cultivation media in relation to strain development for industrial application is reviewed. Heterologous protein production and pentose utilization by
Url:
DOI: 10.1186/1475-2859-4-31
PubMed: 16283927
PubMed Central: 1316877
Affiliations:
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PMC:1316877Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>The composition of cultivation media in relation to strain development for industrial application is reviewed. Heterologous protein production and pentose utilization by <italic>Saccharomyces cerevisiae </italic>
are used to illustrate the influence of media composition at different stages of strain construction and strain development. The effects of complex, defined and industrial media are compared. Auxotrophic strains and strain stability are discussed. Media for heterologous protein production and for bulk bio-commodity production are summarized.</p>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Microb Cell Fact</journal-id>
<journal-title>Microbial Cell Factories</journal-title>
<issn pub-type="epub">1475-2859</issn>
<publisher><publisher-name>BioMed Central</publisher-name>
<publisher-loc>London</publisher-loc>
</publisher>
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<article-id pub-id-type="pmc">1316877</article-id>
<article-id pub-id-type="publisher-id">1475-2859-4-31</article-id>
<article-id pub-id-type="doi">10.1186/1475-2859-4-31</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Review</subject>
</subj-group>
</article-categories>
<title-group><article-title>Role of cultivation media in the development of yeast strains for large scale industrial use</article-title>
</title-group>
<contrib-group><contrib id="A1" corresp="yes" contrib-type="author"><name><surname>Hahn-Hägerdal</surname>
<given-names>Bärbel</given-names>
</name>
<xref ref-type="aff" rid="I1">1</xref>
<email>barbel.hahn-hagerdal@tmb.lth.se</email>
</contrib>
<contrib id="A2" contrib-type="author"><name><surname>Karhumaa</surname>
<given-names>Kaisa</given-names>
</name>
<xref ref-type="aff" rid="I1">1</xref>
<email>kaisa.karhumaa@tmb.lth.se</email>
</contrib>
<contrib id="A3" contrib-type="author"><name><surname>Larsson</surname>
<given-names>Christer U</given-names>
</name>
<xref ref-type="aff" rid="I1">1</xref>
<email>christer.larsson@tmb.lth.se</email>
</contrib>
<contrib id="A4" contrib-type="author"><name><surname>Gorwa-Grauslund</surname>
<given-names>Marie</given-names>
</name>
<xref ref-type="aff" rid="I1">1</xref>
<email>Marie-Francoise.Gorwa@tmb.lth.se</email>
</contrib>
<contrib id="A5" contrib-type="author"><name><surname>Görgens</surname>
<given-names>Johann</given-names>
</name>
<xref ref-type="aff" rid="I2">2</xref>
<email>jgorgens@sun.ac.za</email>
</contrib>
<contrib id="A6" contrib-type="author"><name><surname>van Zyl</surname>
<given-names>Willem H</given-names>
</name>
<xref ref-type="aff" rid="I3">3</xref>
<email>WHVZ@sun.ac.za</email>
</contrib>
</contrib-group>
<aff id="I1"><label>1</label>
Applied Microbiology, LTH/Lund University, P O Box 124, SE-221 00 Lund, Sweden</aff>
<aff id="I2"><label>2</label>
Department of Process Engineering, Stellenbosch University, Private Bag X1, Stellenbosch, 7602, South Africa</aff>
<aff id="I3"><label>3</label>
Department of Microbiology, Stellenbosch University, Private Bag X1, Stellenbosch</aff>
<pub-date pub-type="collection"><year>2005</year>
</pub-date>
<pub-date pub-type="epub"><day>10</day>
<month>11</month>
<year>2005</year>
</pub-date>
<volume>4</volume>
<fpage>31</fpage>
<lpage>31</lpage>
<ext-link ext-link-type="uri" xlink:href="http://www.microbialcellfactories.com/content/4/1/31"></ext-link>
<history><date date-type="received"><day>30</day>
<month>9</month>
<year>2005</year>
</date>
<date date-type="accepted"><day>10</day>
<month>11</month>
<year>2005</year>
</date>
</history>
<copyright-statement>Copyright © 2005 Hahn-Hägerdal et al; licensee BioMed Central Ltd.</copyright-statement>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0"><p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/2.0"></ext-link>
), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p>
</license>
<abstract><p>The composition of cultivation media in relation to strain development for industrial application is reviewed. Heterologous protein production and pentose utilization by <italic>Saccharomyces cerevisiae </italic>
are used to illustrate the influence of media composition at different stages of strain construction and strain development. The effects of complex, defined and industrial media are compared. Auxotrophic strains and strain stability are discussed. Media for heterologous protein production and for bulk bio-commodity production are summarized.</p>
</abstract>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>Afrique du Sud</li>
<li>Suède</li>
</country>
</list>
<tree><noCountry><name sortKey="Van Zyl, Willem H" sort="Van Zyl, Willem H" uniqKey="Van Zyl W" first="Willem H" last="Van Zyl">Willem H. Van Zyl</name>
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<country name="Suède"><noRegion><name sortKey="Hahn H Gerdal, B Rbel" sort="Hahn H Gerdal, B Rbel" uniqKey="Hahn H Gerdal B" first="B Rbel" last="Hahn-H Gerdal">B Rbel Hahn-H Gerdal</name>
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<name sortKey="Gorwa Grauslund, Marie" sort="Gorwa Grauslund, Marie" uniqKey="Gorwa Grauslund M" first="Marie" last="Gorwa-Grauslund">Marie Gorwa-Grauslund</name>
<name sortKey="Karhumaa, Kaisa" sort="Karhumaa, Kaisa" uniqKey="Karhumaa K" first="Kaisa" last="Karhumaa">Kaisa Karhumaa</name>
<name sortKey="Larsson, Christer U" sort="Larsson, Christer U" uniqKey="Larsson C" first="Christer U" last="Larsson">Christer U. Larsson</name>
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<country name="Afrique du Sud"><noRegion><name sortKey="Gorgens, Johann" sort="Gorgens, Johann" uniqKey="Gorgens J" first="Johann" last="Görgens">Johann Görgens</name>
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