Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony
Identifieur interne : 000E95 ( Istex/Corpus ); précédent : 000E94; suivant : 000E96Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony
Auteurs : Shinya S. Suzuki ; Grant K. SmithSource :
- Electroencephalography and Clinical Neurophysiology [ 0013-4694 ] ; 1987.
Abstract
Spontaneous EEG and unit activities were recorded from the CA1 region of the dorsal hippocampus by means of a movable microelectrode in normal behaving rats. Large amplitude (< 4mV) negative EEG spikes (SPKs) of 40–100 msec duration with frequencies in the range of 0.2–5/sec were consistently recorded from the middle apical dendritic layer (stratum radiatum) during awake immobility, grooming and slow-wave sleep. SPKs were replaced by rhythmical slow activity (RSA) during walking and paradoxical sleep. Laminar analysis indicated that SPKs were positive in stratum oriens, negative in stratum radiatum and polarity reversal just below stratum pyramidale. Peak positivity (about 1 mV on average) and peak negativity (2 mV) occurred some 80 μm above and 200 μm below the reversal point, respectively. The SPKs were invariably accompanied by synchronous burst discharges in stratum pyramidale. Bilateral recordings demonstrated that SPKs occurred synchronously in large areas of the CA1 field of the two hippocampi. These results suggest that the SPK represents a massive synaptic excitation of middle apical dendrites triggering synchronous burst discharges in a population of pyramidal cell bodies. A possibility was discussed that these non-pathological SPKs and interictal spikes share some common underlying mechanisms.
Url:
DOI: 10.1016/0013-4694(87)90123-4
Links to Exploration step
ISTEX:7F1E80AF0618294C8033650759976BD3047718E2Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</title><author><name sortKey="Suzuki, Shinya S" sort="Suzuki, Shinya S" uniqKey="Suzuki S" first="Shinya S." last="Suzuki">Shinya S. Suzuki</name><affiliation><mods:affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</mods:affiliation></affiliation></author><author><name sortKey="Smith, Grant K" sort="Smith, Grant K" uniqKey="Smith G" first="Grant K." last="Smith">Grant K. Smith</name><affiliation><mods:affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:7F1E80AF0618294C8033650759976BD3047718E2</idno><date when="1987" year="1987">1987</date><idno type="doi">10.1016/0013-4694(87)90123-4</idno><idno type="url">https://api.istex.fr/document/7F1E80AF0618294C8033650759976BD3047718E2/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000E95</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000E95</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</title><author><name sortKey="Suzuki, Shinya S" sort="Suzuki, Shinya S" uniqKey="Suzuki S" first="Shinya S." last="Suzuki">Shinya S. Suzuki</name><affiliation><mods:affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</mods:affiliation></affiliation></author><author><name sortKey="Smith, Grant K" sort="Smith, Grant K" uniqKey="Smith G" first="Grant K." last="Smith">Grant K. Smith</name><affiliation><mods:affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Electroencephalography and Clinical Neurophysiology</title><title level="j" type="abbrev">EEG</title><idno type="ISSN">0013-4694</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1987">1987</date><biblScope unit="volume">67</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="348">348</biblScope><biblScope unit="page" to="359">359</biblScope></imprint><idno type="ISSN">0013-4694</idno></series><idno type="istex">7F1E80AF0618294C8033650759976BD3047718E2</idno><idno type="DOI">10.1016/0013-4694(87)90123-4</idno><idno type="PII">0013-4694(87)90123-4</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0013-4694</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Spontaneous EEG and unit activities were recorded from the CA1 region of the dorsal hippocampus by means of a movable microelectrode in normal behaving rats. Large amplitude (< 4mV) negative EEG spikes (SPKs) of 40–100 msec duration with frequencies in the range of 0.2–5/sec were consistently recorded from the middle apical dendritic layer (stratum radiatum) during awake immobility, grooming and slow-wave sleep. SPKs were replaced by rhythmical slow activity (RSA) during walking and paradoxical sleep. Laminar analysis indicated that SPKs were positive in stratum oriens, negative in stratum radiatum and polarity reversal just below stratum pyramidale. Peak positivity (about 1 mV on average) and peak negativity (2 mV) occurred some 80 μm above and 200 μm below the reversal point, respectively. The SPKs were invariably accompanied by synchronous burst discharges in stratum pyramidale. Bilateral recordings demonstrated that SPKs occurred synchronously in large areas of the CA1 field of the two hippocampi. These results suggest that the SPK represents a massive synaptic excitation of middle apical dendrites triggering synchronous burst discharges in a population of pyramidal cell bodies. A possibility was discussed that these non-pathological SPKs and interictal spikes share some common underlying mechanisms.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Shinya S. Suzuki</name><affiliations><json:string>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</json:string></affiliations></json:item><json:item><name>Grant K. Smith</name><affiliations><json:string>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Hippocampal EEG spike</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>CA1 region</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Behavioral correlation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Laminar profile</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Bilateral synchrony</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Rat</value></json:item></subject><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>Spontaneous EEG and unit activities were recorded from the CA1 region of the dorsal hippocampus by means of a movable microelectrode in normal behaving rats. Large amplitude (> 4mV) negative EEG spikes (SPKs) of 40–100 msec duration with frequencies in the range of 0.2–5/sec were consistently recorded from the middle apical dendritic layer (stratum radiatum) during awake immobility, grooming and slow-wave sleep. SPKs were replaced by rhythmical slow activity (RSA) during walking and paradoxical sleep. Laminar analysis indicated that SPKs were positive in stratum oriens, negative in stratum radiatum and polarity reversal just below stratum pyramidale. Peak positivity (about 1 mV on average) and peak negativity (2 mV) occurred some 80 μm above and 200 μm below the reversal point, respectively. The SPKs were invariably accompanied by synchronous burst discharges in stratum pyramidale. Bilateral recordings demonstrated that SPKs occurred synchronously in large areas of the CA1 field of the two hippocampi. These results suggest that the SPK represents a massive synaptic excitation of middle apical dendrites triggering synchronous burst discharges in a population of pyramidal cell bodies. A possibility was discussed that these non-pathological SPKs and interictal spikes share some common underlying mechanisms.</abstract><qualityIndicators><score>7.316</score><pdfVersion>1.2</pdfVersion><pdfPageSize>540 x 720 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>6</keywordCount><abstractCharCount>1325</abstractCharCount><pdfWordCount>6550</pdfWordCount><pdfCharCount>38479</pdfCharCount><pdfPageCount>12</pdfPageCount><abstractWordCount>193</abstractWordCount></qualityIndicators><title>Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</title><pii><json:string>0013-4694(87)90123-4</json:string></pii><genre><json:string>research-article</json:string></genre><serie><volume>Vol. 2</volume><pages><first>23</first></pages><language><json:string>unknown</json:string></language><title>Sleep Research</title></serie><host><volume>67</volume><pii><json:string>S0013-4694(00)X0292-1</json:string></pii><pages><last>359</last><first>348</first></pages><issn><json:string>0013-4694</json:string></issn><issue>4</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><title>Electroencephalography and Clinical Neurophysiology</title><publicationDate>1987</publicationDate></host><categories><wos><json:string>CLINICAL NEUROLOGY</json:string><json:string>ENGINEERING, BIOMEDICAL</json:string></wos></categories><publicationDate>1987</publicationDate><copyrightDate>1987</copyrightDate><doi><json:string>10.1016/0013-4694(87)90123-4</json:string></doi><id>7F1E80AF0618294C8033650759976BD3047718E2</id><score>0.052793976</score><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/7F1E80AF0618294C8033650759976BD3047718E2/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/7F1E80AF0618294C8033650759976BD3047718E2/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/7F1E80AF0618294C8033650759976BD3047718E2/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1987</date></publicationStmt><notesStmt><note>This work was supported in part by Grant 7465 from the Natural Sciences and Engineering Research Council of Canada.</note><note type="content">Section title: Experimental section</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</title><author xml:id="author-1"><persName><forename type="first">Shinya S.</forename><surname>Suzuki</surname></persName><note type="correspondence"><p>Correspondence to: S.S. Suzuki, Department of Neuroscience, Mitsubishi-Kasei Institute of Life Sciences, 11 Minamiooya, Machida-shi, Tokyo 194, Japan.</p></note><affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</affiliation></author><author xml:id="author-2"><persName><forename type="first">Grant K.</forename><surname>Smith</surname></persName><affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</affiliation></author></analytic><monogr><title level="j">Electroencephalography and Clinical Neurophysiology</title><title level="j" type="abbrev">EEG</title><idno type="pISSN">0013-4694</idno><idno type="PII">S0013-4694(00)X0292-1</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1987"></date><biblScope unit="volume">67</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="348">348</biblScope><biblScope unit="page" to="359">359</biblScope></imprint></monogr><idno type="istex">7F1E80AF0618294C8033650759976BD3047718E2</idno><idno type="DOI">10.1016/0013-4694(87)90123-4</idno><idno type="PII">0013-4694(87)90123-4</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1987</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Spontaneous EEG and unit activities were recorded from the CA1 region of the dorsal hippocampus by means of a movable microelectrode in normal behaving rats. Large amplitude (< 4mV) negative EEG spikes (SPKs) of 40–100 msec duration with frequencies in the range of 0.2–5/sec were consistently recorded from the middle apical dendritic layer (stratum radiatum) during awake immobility, grooming and slow-wave sleep. SPKs were replaced by rhythmical slow activity (RSA) during walking and paradoxical sleep. Laminar analysis indicated that SPKs were positive in stratum oriens, negative in stratum radiatum and polarity reversal just below stratum pyramidale. Peak positivity (about 1 mV on average) and peak negativity (2 mV) occurred some 80 μm above and 200 μm below the reversal point, respectively. The SPKs were invariably accompanied by synchronous burst discharges in stratum pyramidale. Bilateral recordings demonstrated that SPKs occurred synchronously in large areas of the CA1 field of the two hippocampi. These results suggest that the SPK represents a massive synaptic excitation of middle apical dendrites triggering synchronous burst discharges in a population of pyramidal cell bodies. A possibility was discussed that these non-pathological SPKs and interictal spikes share some common underlying mechanisms.</p></abstract><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>Hippocampal EEG spike</term></item><item><term>CA1 region</term></item><item><term>Behavioral correlation</term></item><item><term>Laminar profile</term></item><item><term>Bilateral synchrony</term></item><item><term>Rat</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1987">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/7F1E80AF0618294C8033650759976BD3047718E2/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>EEG</jid><aid>87901234</aid><ce:pii>0013-4694(87)90123-4</ce:pii><ce:doi>10.1016/0013-4694(87)90123-4</ce:doi><ce:copyright type="unknown" year="1987"></ce:copyright></item-info><head><ce:article-footnote><ce:label>☆</ce:label><ce:note-para>This work was supported in part by Grant 7465 from the Natural Sciences and Engineering Research Council of Canada.</ce:note-para></ce:article-footnote><ce:dochead><ce:textfn>Experimental section</ce:textfn></ce:dochead><ce:title>Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</ce:title><ce:author-group><ce:author><ce:given-name>Shinya S.</ce:given-name><ce:surname>Suzuki</ce:surname><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Grant K.</ce:given-name><ce:surname>Smith</ce:surname></ce:author><ce:affiliation><ce:textfn>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Correspondence to: S.S. Suzuki, Department of Neuroscience, Mitsubishi-Kasei Institute of Life Sciences, 11 Minamiooya, Machida-shi, Tokyo 194, Japan.</ce:text></ce:correspondence></ce:author-group><ce:date-accepted day="17" month="3" year="1987"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Spontaneous EEG and unit activities were recorded from the CA1 region of the dorsal hippocampus by means of a movable microelectrode in normal behaving rats. Large amplitude (< 4mV) negative EEG spikes (SPKs) of 40–100 msec duration with frequencies in the range of 0.2–5/sec were consistently recorded from the middle apical dendritic layer (stratum radiatum) during awake immobility, grooming and slow-wave sleep. SPKs were replaced by rhythmical slow activity (RSA) during walking and paradoxical sleep. Laminar analysis indicated that SPKs were positive in stratum oriens, negative in stratum radiatum and polarity reversal just below stratum pyramidale. Peak positivity (about 1 mV on average) and peak negativity (2 mV) occurred some 80 μm above and 200 μm below the reversal point, respectively. The SPKs were invariably accompanied by synchronous burst discharges in stratum pyramidale. Bilateral recordings demonstrated that SPKs occurred synchronously in large areas of the CA1 field of the two hippocampi. These results suggest that the SPK represents a massive synaptic excitation of middle apical dendrites triggering synchronous burst discharges in a population of pyramidal cell bodies. A possibility was discussed that these non-pathological SPKs and interictal spikes share some common underlying mechanisms.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>Hippocampal EEG spike</ce:text></ce:keyword><ce:keyword><ce:text>CA1 region</ce:text></ce:keyword><ce:keyword><ce:text>Behavioral correlation</ce:text></ce:keyword><ce:keyword><ce:text>Laminar profile</ce:text></ce:keyword><ce:keyword><ce:text>Bilateral synchrony</ce:text></ce:keyword><ce:keyword><ce:text>Rat</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony</title></titleInfo><name type="personal"><namePart type="given">Shinya S.</namePart><namePart type="family">Suzuki</namePart><affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</affiliation><description>Correspondence to: S.S. Suzuki, Department of Neuroscience, Mitsubishi-Kasei Institute of Life Sciences, 11 Minamiooya, Machida-shi, Tokyo 194, Japan.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Grant K.</namePart><namePart type="family">Smith</namePart><affiliation>Department of Psychology, McMaster University, Hamilton, Ont. L8S 4K1 Canada</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1987</dateIssued><copyrightDate encoding="w3cdtf">1987</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Spontaneous EEG and unit activities were recorded from the CA1 region of the dorsal hippocampus by means of a movable microelectrode in normal behaving rats. Large amplitude (< 4mV) negative EEG spikes (SPKs) of 40–100 msec duration with frequencies in the range of 0.2–5/sec were consistently recorded from the middle apical dendritic layer (stratum radiatum) during awake immobility, grooming and slow-wave sleep. SPKs were replaced by rhythmical slow activity (RSA) during walking and paradoxical sleep. Laminar analysis indicated that SPKs were positive in stratum oriens, negative in stratum radiatum and polarity reversal just below stratum pyramidale. Peak positivity (about 1 mV on average) and peak negativity (2 mV) occurred some 80 μm above and 200 μm below the reversal point, respectively. The SPKs were invariably accompanied by synchronous burst discharges in stratum pyramidale. Bilateral recordings demonstrated that SPKs occurred synchronously in large areas of the CA1 field of the two hippocampi. These results suggest that the SPK represents a massive synaptic excitation of middle apical dendrites triggering synchronous burst discharges in a population of pyramidal cell bodies. A possibility was discussed that these non-pathological SPKs and interictal spikes share some common underlying mechanisms.</abstract><note>This work was supported in part by Grant 7465 from the Natural Sciences and Engineering Research Council of Canada.</note><note type="content">Section title: Experimental section</note><subject><genre>Keywords</genre><topic>Hippocampal EEG spike</topic><topic>CA1 region</topic><topic>Behavioral correlation</topic><topic>Laminar profile</topic><topic>Bilateral synchrony</topic><topic>Rat</topic></subject><relatedItem type="host"><titleInfo><title>Electroencephalography and Clinical Neurophysiology</title></titleInfo><titleInfo type="abbreviated"><title>EEG</title></titleInfo><genre type="journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">198710</dateIssued></originInfo><identifier type="ISSN">0013-4694</identifier><identifier type="PII">S0013-4694(00)X0292-1</identifier><part><date>198710</date><detail type="volume"><number>67</number><caption>vol.</caption></detail><detail type="issue"><number>4</number><caption>no.</caption></detail><extent unit="issue pages"><start>P73</start><end>P88</end></extent><extent unit="issue pages"><start>289</start><end>388</end></extent><extent unit="pages"><start>348</start><end>359</end></extent></part></relatedItem><identifier type="istex">7F1E80AF0618294C8033650759976BD3047718E2</identifier><identifier type="DOI">10.1016/0013-4694(87)90123-4</identifier><identifier type="PII">0013-4694(87)90123-4</identifier><recordInfo><recordContentSource>ELSEVIER</recordContentSource></recordInfo></mods></metadata></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/CobaltMaghrebV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E95 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000E95 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Terre
|area= CobaltMaghrebV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:7F1E80AF0618294C8033650759976BD3047718E2
|texte= Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony
}}
| This area was generated with Dilib version V0.6.32. |  |