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J F Chatal (France) ; A Faivre-Chauvet ; M Bardies ; P Peltier ; E Gautherot ; J Barbet | Bifunctional antibodies for radioimmunotherapy. |
| 000241 (1993) |
P Peltier (France) ; C Curtet ; J F Chatal ; J M Le Doussal ; G Daniel ; G Aillet ; A Gruaz-Guyon ; J Barbet ; M Delaage | Radioimmunodetection of medullary thyroid cancer using a bispecific anti-CEA/anti-indium-DTPA antibody and an indium-111-labeled DTPA dimer. |
| 000248 (1993) |
J M Le Doussal (France) ; A Chetanneau ; A Gruaz-Guyon ; M Martin ; E Gautherot ; P A Lehur ; J F Chatal ; M Delaage ; J Barbet | Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: pharmacokinetics, biodistribution, scintigraphy and immune response. |
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F Kraeber-Bodéré (France) ; A Faivre-Chauvet ; C Saï-Maurel ; L Campion ; M Fiche ; E Gautherot ; J Le Boterff ; J Barbet ; J F Chatal ; P Thédrez | Toxicity and efficacy of radioimmunotherapy in carcinoembryonic antigen-producing medullary thyroid cancer xenograft: comparison of iodine 131-labeled F(ab')2 and pretargeted bivalent hapten and evaluation of repeated injections. |
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A Devys (France) ; P Thedrez ; E Gautherot ; A Faivre-Chauvet ; C Saï-Maurel ; E Rouvier ; J L Auget ; J Barbet ; J F Chatal | Comparative targeting of human colon-carcinoma multicell spheroids using one- and two-step (bispecific antibody) techniques. |
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A Chetanneau (France) ; J Barbet ; P Peltier ; J M Le Doussal ; A Gruaz-Guyon ; A M Bernard ; I Resche ; E Rouvier ; P Bourguet ; M Delaage | Pretargetted imaging of colorectal cancer recurrences using an 111In-labelled bivalent hapten and a bispecific antibody conjugate. |
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J Barbet (France) ; J M Le Doussal ; A Gruaz-Guyon ; M Martin ; E Gautherot ; M Delaage | Computer calculation of multiple binding equilibrium isotherms: application to the binding of bivalent ligands to antibodies interacting with cell surface Fc-receptors. |
| 000272 (1991) |
J M Le Doussal (France) ; E Gautherot ; M Martin ; J Barbet ; M Delaage | Enhanced in vivo targeting of an asymmetric bivalent hapten to double-antigen-positive mouse B cells with monoclonal antibody conjugate cocktails. |
| 000275 (1990) |
J M Le Doussal (France) ; A Gruaz-Guyon ; M Martin ; E Gautherot ; M Delaage ; J Barbet | Targeting of indium 111-labeled bivalent hapten to human melanoma mediated by bispecific monoclonal antibody conjugates: imaging of tumors hosted in nude mice. |
| 000287 (1989) |
J M Le Doussal (France) ; M Martin ; E Gautherot ; M Delaage ; J Barbet | In vitro and in vivo targeting of radiolabeled monovalent and divalent haptens with dual specificity monoclonal antibody conjugates: enhanced divalent hapten affinity for cell-bound antibody conjugate. |
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L Morandeau (France) ; E Benoist ; A Loussouarn ; A Ouadi ; P Lesaec ; M Mougin ; A Faivre-Chauvet ; J Le Boterff ; J F Chatal ; J Barbet ; J F Gestin | Synthesis of new bivalent peptides for applications in the Affinity Enhancement System. |
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E Gautherot (France) ; F Kraeber-Bodéré ; L Daniel ; M Fiche ; E Rouvier ; C Saï-Maurel ; P Thedrez ; J F Chatal ; J Barbet | Immunohistology of carcinoembryonic antigen (CEA)-expressing tumors grafted in nude mice after radioimmunotherapy with 131I-labeled bivalent hapten and anti-CEA x antihapten bispecific antibody. |
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J Barbet (France) ; P Peltier ; S Bardet ; J P Vuillez ; I Bachelot ; S Denet ; P Olivier ; F Leccia ; B Corcuff ; D Huglo ; C Proye ; E Rouvier ; P Meyer ; J F Chatal | Radioimmunodetection of medullary thyroid carcinoma using indium-111 bivalent hapten and anti-CEA x anti-DTPA-indium bispecific antibody. |
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E Gautherot (France) ; J Bouhou ; J M Le Doussal ; C Manetti ; M Martin ; E Rouvier ; J Barbet | Therapy for colon carcinoma xenografts with bispecific antibody-targeted, iodine-131-labeled bivalent hapten. |
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A Faivre-Chauvet (France) ; R C Mease ; A Chetanneau ; M Bardiès ; C Sai-Maurel ; G E Meinken ; S C Srivastava ; J F Chatal ; J F Gestin | Pre-clinical and clinical studies of two new bifunctional chelating agents for immunoscintigraphy with 111In-anti-CEA monoclonal antibody. |
| 000244 (1993) |
A Faivre-Chauvet (France) ; J F Gestin ; R C Mease ; C Sai-Maurel ; P Thédrez ; M Slinkin ; G E Meinken ; S C Srivastava ; J F Chatal | Introduction of five potentially metabolizable linking groups between 111In-cyclohexyl EDTA derivatives and F(ab')2 fragments of anti-carcinoembryonic antigen antibody--II. Comparative pharmacokinetics and biodistribution in human colorectal carcinoma-bearing nude mice. |
| 000245 (1993) |
J F Gestin (France) ; A Faivre-Chauvet ; R C Mease ; C Sai-Maurel ; P Thédrez ; M Slinkin ; G E Meinken ; S C Srivastava ; J F Chatal | Introduction of five potentially metabolizable linking groups between 111In-cyclohexyl EDTA derivatives and F(ab')2 fragments of anti-carcinoembryonic antigen antibody--I. A new reproducible synthetic method. |
| 000249 (1993) |
M A Slinkin (France) ; C Curtet ; A Faivre-Chauvet ; C Sai-Maurel ; J F Gestin ; V P Torchilin ; J F Chatal | Biodistribution of anti-CEA F(ab')2 fragments conjugated with chelating polymers: influence of conjugate electron charge on tumor uptake and blood clearance. |
| 000254 (1992) |
M Bardiès (France) ; P Thedrez ; J F Gestin ; B M Marcille ; D Guerreau ; A Faivre-Chauvet ; M Mahé ; C Sai-Maurel ; J F Chatal | Use of multi-cell spheroids of ovarian carcinoma as an intraperitoneal radio-immunotherapy model: uptake, retention kinetics and dosimetric evaluation. |
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J M Le Doussal (France) ; J Barbet ; M Delaage | Bispecific-antibody-mediated targeting of radiolabeled bivalent haptens: theoretical, experimental and clinical results. |
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M Mougin-Degraef (France) ; C Bourdeau ; E Jestin ; C Saï-Maurel ; M Bourgeois ; P Remaud-Le Saëc ; P Thédrez ; J-F Gestin ; J Barbet ; A Faivre-Chauvet | Doubly radiolabeled liposomes for pretargeted radioimmunotherapy. |
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J P Vuillez (France) ; D Moro ; P Y Brichon ; E Rouvier ; E Brambilla ; J Barbet ; P Peltier ; P Meyer ; R Sarrazin ; C Brambilla | Two-step immunoscintigraphy for non-small-cell lung cancer staging using a bispecific anti-CEA/anti-indium-DTPA antibody and an indium-111-labeled DTPA dimer. |
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C Manetti (France) ; J M Le Doussal ; E Rouvier ; A Gruaz-Guyon ; J Barbet | Intracellular uptake and catabolism of anti-IgM antibodies and bi-specific antibody-targeted hapten by B-lymphoma cells. |
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V Boden (France) ; C Colin ; J Barbet ; J M Le Doussal ; M Vijayalakshmi | Complementary approach for the determination of histidine in the metal-binding site of an anti-DTPA-indium monoclonal antibody. |
| 000237 (1993) |
P Peltier (France) ; J P Dutin ; J F Chatal ; P Fumoleau ; P Bourguet ; J C Liehn ; J P Vuillez ; J Y Hérry ; A Loboguerrero | Usefulness of imaging ovarian cancer recurrence with In-111-labeled monoclonal antibody (OC 125) specific for CA 125 antigen. The INSERM Research Network (Nantes, Rennes, Reims, Vuillejuif, Saclay. |
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J P Vuillez (France) ; P Peltier ; J P Caravel ; A Chetanneau ; J C Saccavini ; J F Chatal | Immunoscintigraphy using 111In-labeled F(ab')2 fragments of anticarcinoembryonic antigen monoclonal antibody for detecting recurrences of medullary thyroid carcinoma. |
| 000259 (1992) |
P Peltier (France) ; K Wiharto ; J P Dutin ; J F Chatal ; P Bourguet ; J C Liehn ; J P Vuillez ; J Y Hérry ; A Loboguerrero | Correlative imaging study in the diagnosis of ovarian cancer recurrences. The INSERM Research Network (Nantes, Rennes, Reims, Villejuif, Saclay), France. |
| 000266 (1991) |
J P Vuillez (France) ; P Peltier ; J C Mayer ; F Dubois ; A Chetanneau ; P Fumoleau ; A Bertrand ; J F Chatal | Reproducibility of image interpretation in immunoscintigraphy performed with indium-111- and iodine-131-labeled OC125 F(ab')2 antibody injected into the same patients. |
| 000271 (1991) |
P De Faucal (France) ; P Peltier ; B Planchon ; B Dupas ; M D Touze ; D Baron ; T Scaible ; H J Berger ; J F Chatal | Evaluation of indium-111-labeled antifibrin monoclonal antibody for the diagnosis of venous thrombotic disease. |
| 000289 (1989) |
A Chetanneau (France) ; P A Lehur ; D Ripoche ; P Peltier ; J C Saccavini ; J P Vuillez ; N Tournemaine ; P Thedrez ; J F Chatal | Histological correlation of 17 prospective immunoscintigraphies of recurrences of colorectal carcinomas using indium-111-labeled anti-cea and(or) 19-9 monoclonal antibodies. |
| 000292 (1989) |
J F Chatal (France) ; J C Saccavini ; J F Gestin ; P Thédrez ; C Curtet ; M Kremer ; D Guerreau ; D Nolibé ; P Fumoleau ; Y Guillard | Biodistribution of indium-111-labeled OC 125 monoclonal antibody intraperitoneally injected into patients operated on for ovarian carcinomas. |
| 000293 (1989) |
P Thédrez (France) ; J C Saccavini ; D Nolibé ; J P Simoen ; D Guerreau ; J F Gestin ; M Kremer ; J F Chatal | Biodistribution of indium-111-labeled OC 125 monoclonal antibody after intraperitoneal injection in nude mice intraperitoneally grafted with ovarian carcinoma. |
| 000311 (????) |
V Boden (France) ; C Colin ; J Barbet ; J M Le Doussal ; M Vijayalakshmi | Preliminary study of the metal binding site of an anti-DTPA-indium antibody by equilibrium binding immunoassays and immobilized metal ion affinity chromatography. |
| 000084 (2007) |
A Sézeur (France) ; F P Châtelet ; Ch Cywiner ; Cl de Labriolle-Vaylet ; C Chastang ; Cl Billotey ; M Malafosse ; D Gallot ; P Betton ; F Montravers ; S Carvajal-Gonzalez ; S Askienazy ; J N Talbot ; J D Rain ; G Milhaud ; G Saumon ; J Barbet ; A Gruaz-Guyon | Pathology underrates colon cancer extranodal and nodal metastases; ex vivo radioimmunodetection helps staging. |
| 000279 (1990) |
A Chetanneau (France) ; R P Baum ; P A Lehur ; J C Liehn ; A C Perkins ; R Bares ; P Bourguet ; J Y Herry ; J C Saccavini ; J F Chatal | Multi-centre immunoscintigraphic study using indium-111-labelled CEA-specific and/or 19-9 monoclonal antibody F(ab')2 fragments. |
| 000283 (1990) |
C Curtet (France) ; J P Vuillez ; G Daniel ; G Aillet ; A Chetanneau ; J Visset ; M Kremer ; P Thédrez ; J F Chatal | Feasibility study of radioimmunoguided surgery of colorectal carcinomas using indium-111 CEA-specific monoclonal antibody. |
| 000316 (????) |
A Hamy (France) ; C Curtet ; J Paineau ; J F Chatal ; J Visset | Feasibility of radioimmunoguided surgery of colorectal carcinoma using indium 111 CEA specific antibody and simulation with a phantom using 2 steps targetting with bispecific antibody. |
| 000317 (????) |
M Hillairet de Boisferon (France) ; O Raguin ; M Dussaillant ; W Rostène ; J Barbet ; A Gruaz-Guyon | Enhanced targeting specificity to tumor cells by simultaneous recognition of two antigens. |
