Cyberinfrastructure for PathoSystems Biology
Identifieur interne : 000016 ( Istex/Corpus ); précédent : 000015; suivant : 000017Cyberinfrastructure for PathoSystems Biology
Auteurs : S. SobralSource :
- Lecture Notes in Computer Science [ 0302-9743 ] ; 2005.
Abstract
Abstract: The application of new information and biotechnologies to infectious disease research provides an opportunity to design, develop and deploy a comprehensive cyberinfrastructure for life sciences. The application of integrative approaches including theory, wet experimentation, modeling and simulation and the leveraging of a strong comparative, evolutionary framework has spawned pathosystems biology. I will show examples of how cyberinfrastructure is being developed and used to support pathosystems biology.
Url:
DOI: 10.1007/11532323_3
Links to Exploration step
ISTEX:A100AAD981C3B7283078AF5A91BF5005B3E243EDLe document en format XML
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Sobral</name><affiliation><mods:affiliation>Virginia Bioinformatics Institute at Virginia Tech (0477), 92024, Blacksburg, VA, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: sobral@vt.edu</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A100AAD981C3B7283078AF5A91BF5005B3E243ED</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1007/11532323_3</idno><idno type="url">https://api.istex.fr/document/A100AAD981C3B7283078AF5A91BF5005B3E243ED/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000016</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Cyberinfrastructure for PathoSystems Biology</title><author><name sortKey="Sobral, S" sort="Sobral, S" uniqKey="Sobral S" first="S." last="Sobral">S. Sobral</name><affiliation><mods:affiliation>Virginia Bioinformatics Institute at Virginia Tech (0477), 92024, Blacksburg, VA, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: sobral@vt.edu</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="s">Lecture Notes in Computer Science</title><imprint><date>2005</date></imprint><idno type="ISSN">0302-9743</idno><idno type="eISSN">1611-3349</idno><idno type="ISSN">0302-9743</idno></series><idno type="istex">A100AAD981C3B7283078AF5A91BF5005B3E243ED</idno><idno type="DOI">10.1007/11532323_3</idno><idno type="ChapterID">3</idno><idno type="ChapterID">Chap3</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0302-9743</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The application of new information and biotechnologies to infectious disease research provides an opportunity to design, develop and deploy a comprehensive cyberinfrastructure for life sciences. The application of integrative approaches including theory, wet experimentation, modeling and simulation and the leveraging of a strong comparative, evolutionary framework has spawned pathosystems biology. I will show examples of how cyberinfrastructure is being developed and used to support pathosystems biology.</div></front></TEI><istex><corpusName>springer</corpusName><author><json:item><name>Bruno W. S. Sobral</name><affiliations><json:string>Virginia Bioinformatics Institute at Virginia Tech (0477), 92024, Blacksburg, VA, USA</json:string><json:string>E-mail: sobral@vt.edu</json:string></affiliations></json:item></author><language><json:string>eng</json:string></language><originalGenre><json:string>OriginalPaper</json:string></originalGenre><abstract>Abstract: The application of new information and biotechnologies to infectious disease research provides an opportunity to design, develop and deploy a comprehensive cyberinfrastructure for life sciences. 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Kleinberg</name><affiliations><json:string>Cornell University, Ithaca, NY, USA</json:string></affiliations></json:item><json:item><name>Friedemann Mattern</name><affiliations><json:string>ETH Zurich, Switzerland</json:string></affiliations></json:item><json:item><name>John C. Mitchell</name><affiliations><json:string>Stanford University, CA, USA</json:string></affiliations></json:item><json:item><name>Moni Naor</name><affiliations><json:string>Weizmann Institute of Science, Rehovot, Israel</json:string></affiliations></json:item><json:item><name>Oscar Nierstrasz</name><affiliations><json:string>University of Bern, Switzerland</json:string></affiliations></json:item><json:item><name>C. 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Vardi</name><affiliations><json:string>Rice University, Houston, TX, USA</json:string></affiliations></json:item><json:item><name>Gerhard Weikum</name><affiliations><json:string>Max-Planck Institute of Computer Science, Saarbruecken, Germany</json:string></affiliations></json:item></editor><issn><json:string>0302-9743</json:string></issn><language><json:string>unknown</json:string></language><eissn><json:string>1611-3349</json:string></eissn><title>Lecture Notes in Computer Science</title><copyrightDate>2005</copyrightDate></serie><host><editor><json:item><name>João Carlos Setubal</name><affiliations><json:string>Department of Computer Science, Virginia Bioinformatics Institute and Virginia Polytechnic Institute and State University, Bioinformatics 1, Box 0477, 24060-0477, Blacksburg, VA, USA</json:string><json:string>E-mail: setubal@vbi.vt.edu</json:string></affiliations></json:item><json:item><name>Sergio Verjovski-Almeida</name><affiliations><json:string>Instituto de Quimica, Departamento de Bioquimica, Universidade de Sao Paulo, Av. Prof. Lineu Prestes 748, 05508-000, Sao Paulo, SP, Brazil</json:string><json:string>E-mail: verjo@iq.usp.br</json:string></affiliations></json:item></editor><subject><json:item><value>Computer Science</value></json:item><json:item><value>Computer Science</value></json:item><json:item><value>Database Management</value></json:item><json:item><value>Bioinformatics</value></json:item><json:item><value>Computer Appl. in Life Sciences</value></json:item><json:item><value>Health Informatics</value></json:item><json:item><value>Artificial Intelligence (incl. Robotics)</value></json:item><json:item><value>Algorithm Analysis and Problem Complexity</value></json:item></subject><isbn><json:string>978-3-540-28008-8</json:string></isbn><language><json:string>unknown</json:string></language><eissn><json:string>1611-3349</json:string></eissn><title>Advances in Bioinformatics and Computational Biology</title><bookId><json:string>978-3-540-31861-3</json:string></bookId><volume>3594</volume><pages><last>27</last><first>11</first></pages><issn><json:string>0302-9743</json:string></issn><genre><json:string>book-series</json:string></genre><eisbn><json:string>978-3-540-31861-3</json:string></eisbn><copyrightDate>2005</copyrightDate><doi><json:string>10.1007/11532323</json:string></doi></host><publicationDate>2005</publicationDate><copyrightDate>2005</copyrightDate><doi><json:string>10.1007/11532323_3</json:string></doi><id>A100AAD981C3B7283078AF5A91BF5005B3E243ED</id><score>0.59727925</score><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/A100AAD981C3B7283078AF5A91BF5005B3E243ED/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/A100AAD981C3B7283078AF5A91BF5005B3E243ED/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/A100AAD981C3B7283078AF5A91BF5005B3E243ED/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Cyberinfrastructure for PathoSystems Biology</title><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Springer Berlin Heidelberg</publisher><pubPlace>Berlin, Heidelberg</pubPlace><availability><p>Springer-Verlag Berlin Heidelberg, 2005</p></availability><date>2005</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Cyberinfrastructure for PathoSystems Biology</title><author xml:id="author-1"><persName><forename type="first">Bruno</forename><surname>Sobral</surname></persName><email>sobral@vt.edu</email><affiliation>Virginia Bioinformatics Institute at Virginia Tech (0477), 92024, Blacksburg, VA, USA</affiliation></author></analytic><monogr><title level="m">Advances in Bioinformatics and Computational Biology</title><title level="m" type="sub">Brazilian Symposium on Bioinformatics, BSB 2005, Sao Leopoldo, Brazil, July 27-29, 2005. Proceedings</title><idno type="pISBN">978-3-540-28008-8</idno><idno type="eISBN">978-3-540-31861-3</idno><idno type="pISSN">0302-9743</idno><idno type="eISSN">1611-3349</idno><idno type="DOI">10.1007/11532323</idno><idno type="book-ID">978-3-540-31861-3</idno><idno type="book-title-ID">125602</idno><idno type="book-sequence-number">3594</idno><idno type="book-volume-number">3594</idno><idno type="book-chapter-count">35</idno><editor><persName><forename type="first">João</forename><forename type="first">Carlos</forename><surname>Setubal</surname></persName><email>setubal@vbi.vt.edu</email><affiliation>Department of Computer Science, Virginia Bioinformatics Institute and Virginia Polytechnic Institute and State University, Bioinformatics 1, Box 0477, 24060-0477, Blacksburg, VA, USA</affiliation></editor><editor><persName><forename type="first">Sergio</forename><surname>Verjovski-Almeida</surname></persName><email>verjo@iq.usp.br</email><affiliation>Instituto de Quimica, Departamento de Bioquimica, Universidade de Sao Paulo, Av. 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type="first">M.</forename><surname>Kleinberg</surname></persName><affiliation>Cornell University, Ithaca, NY, USA</affiliation></editor><editor><persName><forename type="first">Friedemann</forename><surname>Mattern</surname></persName><affiliation>ETH Zurich, Switzerland</affiliation></editor><editor><persName><forename type="first">John</forename><forename type="first">C.</forename><surname>Mitchell</surname></persName><affiliation>Stanford University, CA, USA</affiliation></editor><editor><persName><forename type="first">Moni</forename><surname>Naor</surname></persName><affiliation>Weizmann Institute of Science, Rehovot, Israel</affiliation></editor><editor><persName><forename type="first">Oscar</forename><surname>Nierstrasz</surname></persName><affiliation>University of Bern, Switzerland</affiliation></editor><editor><persName><forename type="first">C.</forename><surname>Pandu Rangan</surname></persName><affiliation>Indian Institute of Technology, Madras, India</affiliation></editor><editor><persName><forename type="first">Bernhard</forename><surname>Steffen</surname></persName><affiliation>University of Dortmund, Germany</affiliation></editor><editor><persName><forename type="first">Madhu</forename><surname>Sudan</surname></persName><affiliation>Massachusetts Institute of Technology, MA, USA</affiliation></editor><editor><persName><forename type="first">Demetri</forename><surname>Terzopoulos</surname></persName><affiliation>New York University, NY, USA</affiliation></editor><editor><persName><forename type="first">Dough</forename><surname>Tygar</surname></persName><affiliation>University of California, Berkeley, CA, USA</affiliation></editor><editor><persName><forename type="first">Moshe</forename><forename type="first">Y.</forename><surname>Vardi</surname></persName><affiliation>Rice University, Houston, TX, USA</affiliation></editor><editor><persName><forename type="first">Gerhard</forename><surname>Weikum</surname></persName><affiliation>Max-Planck Institute of Computer Science, Saarbruecken, Germany</affiliation></editor><biblScope><date>2005</date></biblScope><idno type="pISSN">0302-9743</idno><idno type="eISSN">1611-3349</idno><idno type="series-Id">558</idno></series><series><title level="s">Lecture Notes in Bioinformatics</title><editor><persName><forename type="first">David</forename><surname>Hutchison</surname></persName><affiliation>Lancaster University, UK</affiliation></editor><editor><persName><forename type="first">Takeo</forename><surname>Kanade</surname></persName><affiliation>Carnegie Mellon University, Pittsburgh, PA, USA</affiliation></editor><editor><persName><forename type="first">Josef</forename><surname>Kittler</surname></persName><affiliation>University of Surrey, Guildford, UK</affiliation></editor><editor><persName><forename type="first">Jon</forename><forename type="first">M.</forename><surname>Kleinberg</surname></persName><affiliation>Cornell University, Ithaca, NY, USA</affiliation></editor><editor><persName><forename type="first">Friedemann</forename><surname>Mattern</surname></persName><affiliation>ETH Zurich, Switzerland</affiliation></editor><editor><persName><forename type="first">John</forename><forename type="first">C.</forename><surname>Mitchell</surname></persName><affiliation>Stanford University, CA, USA</affiliation></editor><editor><persName><forename type="first">Moni</forename><surname>Naor</surname></persName><affiliation>Weizmann Institute of Science, Rehovot, Israel</affiliation></editor><editor><persName><forename type="first">Oscar</forename><surname>Nierstrasz</surname></persName><affiliation>University of Bern, Switzerland</affiliation></editor><editor><persName><forename type="first">C.</forename><surname>Pandu Rangan</surname></persName><affiliation>Indian Institute of Technology, Madras, India</affiliation></editor><editor><persName><forename type="first">Bernhard</forename><surname>Steffen</surname></persName><affiliation>University of Dortmund, Germany</affiliation></editor><editor><persName><forename type="first">Madhu</forename><surname>Sudan</surname></persName><affiliation>Massachusetts Institute of Technology, MA, USA</affiliation></editor><editor><persName><forename type="first">Demetri</forename><surname>Terzopoulos</surname></persName><affiliation>New York University, NY, USA</affiliation></editor><editor><persName><forename type="first">Dough</forename><surname>Tygar</surname></persName><affiliation>University of California, Berkeley, CA, USA</affiliation></editor><editor><persName><forename type="first">Moshe</forename><forename type="first">Y.</forename><surname>Vardi</surname></persName><affiliation>Rice University, Houston, TX, USA</affiliation></editor><editor><persName><forename type="first">Gerhard</forename><surname>Weikum</surname></persName><affiliation>Max-Planck Institute of Computer Science, Saarbruecken, Germany</affiliation></editor><editor><persName><forename type="first">Sorin</forename><surname>Istrail</surname></persName><affiliation>Celera Genomics, Applied Biosystems, Rockville, MD, USA</affiliation></editor><editor><persName><forename type="first">Pavel</forename><surname>Pevzner</surname></persName><affiliation>University of California, San Diego, CA, USA</affiliation></editor><editor><persName><forename type="first">Michael</forename><surname>Waterman</surname></persName><affiliation>University of Southern California, Los Angeles, CA, USA</affiliation></editor><editor><persName><forename type="first">João</forename><forename type="first">Carlos</forename><surname>Setubal</surname></persName><email>setubal@vbi.vt.edu</email><affiliation>Department of Computer Science, Virginia Bioinformatics Institute and Virginia Polytechnic Institute and 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University</OrgName><OrgAddress><City>Pittsburgh</City><State>PA</State><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff3"><OrgName>University of Surrey</OrgName><OrgAddress><City>Guildford</City><Country>UK</Country></OrgAddress></Affiliation><Affiliation ID="Aff4"><OrgName>Cornell University</OrgName><OrgAddress><City>Ithaca</City><State>NY</State><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff5"><OrgName>ETH Zurich</OrgName><OrgAddress><Country>Switzerland</Country></OrgAddress></Affiliation><Affiliation ID="Aff6"><OrgName>Stanford University</OrgName><OrgAddress><City>CA</City><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff7"><OrgName>Weizmann Institute of Science</OrgName><OrgAddress><City>Rehovot</City><Country>Israel</Country></OrgAddress></Affiliation><Affiliation ID="Aff8"><OrgName>University of Bern</OrgName><OrgAddress><Country>Switzerland</Country></OrgAddress></Affiliation><Affiliation ID="Aff9"><OrgName>Indian Institute of Technology</OrgName><OrgAddress><City>Madras</City><Country>India</Country></OrgAddress></Affiliation><Affiliation ID="Aff10"><OrgName>University of Dortmund</OrgName><OrgAddress><Country>Germany</Country></OrgAddress></Affiliation><Affiliation ID="Aff11"><OrgName>Massachusetts Institute of Technology</OrgName><OrgAddress><City>MA</City><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff12"><OrgName>New York University</OrgName><OrgAddress><City>NY</City><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff13"><OrgName>University of California</OrgName><OrgAddress><City>Berkeley</City><State>CA</State><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff14"><OrgName>Rice University</OrgName><OrgAddress><City>Houston</City><State>TX</State><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff15"><OrgName>Max-Planck Institute of Computer Science</OrgName><OrgAddress><City>Saarbruecken</City><Country>Germany</Country></OrgAddress></Affiliation></EditorGroup></SeriesHeader><SubSeries><SubSeriesInfo><SubSeriesID>5381</SubSeriesID><SubSeriesPrintISSN>0302-9743</SubSeriesPrintISSN><SubSeriesElectronicISSN>1611-3349</SubSeriesElectronicISSN><SubSeriesTitle Language="En">Lecture Notes in Bioinformatics</SubSeriesTitle></SubSeriesInfo><SubSeriesHeader><EditorGroup><Editor AffiliationIDS="Aff16"><EditorName DisplayOrder="Western"><GivenName>Sorin</GivenName><FamilyName>Istrail</FamilyName></EditorName></Editor><Editor AffiliationIDS="Aff17"><EditorName DisplayOrder="Western"><GivenName>Pavel</GivenName><FamilyName>Pevzner</FamilyName></EditorName></Editor><Editor AffiliationIDS="Aff18"><EditorName DisplayOrder="Western"><GivenName>Michael</GivenName><FamilyName>Waterman</FamilyName></EditorName></Editor><Affiliation ID="Aff16"><OrgName>Celera Genomics, Applied Biosystems</OrgName><OrgAddress><City>Rockville</City><State>MD</State><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff17"><OrgName>University of California</OrgName><OrgAddress><City>San Diego</City><State>CA</State><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff18"><OrgName>University of Southern California</OrgName><OrgAddress><City>Los Angeles</City><State>CA</State><Country>USA</Country></OrgAddress></Affiliation></EditorGroup></SubSeriesHeader></SubSeries><Book Language="En"><BookInfo BookProductType="Proceedings" ContainsESM="No" Language="En" MediaType="eBook" NumberingDepth="2" NumberingStyle="ContentOnly" OutputMedium="All" TocLevels="0"><BookID>978-3-540-31861-3</BookID><BookTitle>Advances in Bioinformatics and Computational Biology</BookTitle><BookSubTitle>Brazilian Symposium on Bioinformatics, BSB 2005, Sao Leopoldo, Brazil, July 27-29, 2005. Proceedings</BookSubTitle><BookVolumeNumber>3594</BookVolumeNumber><BookSequenceNumber>3594</BookSequenceNumber><BookDOI>10.1007/11532323</BookDOI><BookTitleID>125602</BookTitleID><BookPrintISBN>978-3-540-28008-8</BookPrintISBN><BookElectronicISBN>978-3-540-31861-3</BookElectronicISBN><BookChapterCount>35</BookChapterCount><BookCopyright><CopyrightHolderName>Springer-Verlag Berlin Heidelberg</CopyrightHolderName><CopyrightYear>2005</CopyrightYear></BookCopyright><BookSubjectGroup><BookSubject Code="I" Type="Primary">Computer Science</BookSubject><BookSubject Code="I18024" Priority="1" Type="Secondary">Database Management</BookSubject><BookSubject Code="L15001" Priority="2" Type="Secondary">Bioinformatics</BookSubject><BookSubject Code="L17004" Priority="3" Type="Secondary">Computer Appl. in Life Sciences</BookSubject><BookSubject Code="H28009" Priority="4" Type="Secondary">Health Informatics</BookSubject><BookSubject Code="I21017" Priority="5" Type="Secondary">Artificial Intelligence (incl. Robotics)</BookSubject><BookSubject Code="I16021" Priority="6" Type="Secondary">Algorithm Analysis and Problem Complexity</BookSubject><SubjectCollection Code="SUCO11645">Computer Science</SubjectCollection></BookSubjectGroup><BookContext><SeriesID>558</SeriesID><SubSeriesID>5381</SubSeriesID></BookContext></BookInfo><BookHeader><EditorGroup><Editor AffiliationIDS="Aff19"><EditorName DisplayOrder="Western"><GivenName>João</GivenName><GivenName>Carlos</GivenName><FamilyName>Setubal</FamilyName></EditorName><Contact><Email>setubal@vbi.vt.edu</Email></Contact></Editor><Editor AffiliationIDS="Aff20"><EditorName DisplayOrder="Western"><GivenName>Sergio</GivenName><FamilyName>Verjovski-Almeida</FamilyName></EditorName><Contact><Email>verjo@iq.usp.br</Email></Contact></Editor><Affiliation ID="Aff19"><OrgDivision>Department of Computer Science</OrgDivision><OrgName>Virginia Bioinformatics Institute and Virginia Polytechnic Institute and State University</OrgName><OrgAddress><Street>Bioinformatics 1</Street><Postbox>Box 0477</Postbox><Postcode>24060-0477</Postcode><City>Blacksburg</City><State>VA</State><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff20"><OrgDivision>Instituto de Quimica, Departamento de Bioquimica</OrgDivision><OrgName>Universidade de Sao Paulo</OrgName><OrgAddress><Street>Av. Prof. Lineu Prestes 748</Street><Postcode>05508-000</Postcode><City>Sao Paulo</City><State>SP</State><Country>Brazil</Country></OrgAddress></Affiliation></EditorGroup></BookHeader><Part ID="Part1"><PartInfo TocLevels="0"><PartID>1</PartID><PartSequenceNumber>1</PartSequenceNumber><PartTitle>Invited Papers</PartTitle><PartChapterCount>4</PartChapterCount><PartContext><SeriesID>558</SeriesID><BookTitle>Advances in Bioinformatics and Computational Biology</BookTitle></PartContext></PartInfo><Chapter ID="Chap3" Language="En"><ChapterInfo ChapterType="OriginalPaper" ContainsESM="No" NumberingDepth="2" NumberingStyle="ContentOnly" TocLevels="0"><ChapterID>3</ChapterID><ChapterDOI>10.1007/11532323_3</ChapterDOI><ChapterSequenceNumber>3</ChapterSequenceNumber><ChapterTitle Language="En">Cyberinfrastructure for PathoSystems Biology</ChapterTitle><ChapterFirstPage>11</ChapterFirstPage><ChapterLastPage>27</ChapterLastPage><ChapterCopyright><CopyrightHolderName>Springer-Verlag Berlin Heidelberg</CopyrightHolderName><CopyrightYear>2005</CopyrightYear></ChapterCopyright><ChapterGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ChapterGrants><ChapterContext><SeriesID>558</SeriesID><PartID>1</PartID><BookID>978-3-540-31861-3</BookID><BookTitle>Advances in Bioinformatics and Computational Biology</BookTitle></ChapterContext></ChapterInfo><ChapterHeader><AuthorGroup><Author AffiliationIDS="Aff21"><AuthorName DisplayOrder="Western"><GivenName>Bruno</GivenName><GivenName>W.</GivenName><GivenName>S.</GivenName><FamilyName>Sobral</FamilyName></AuthorName><Contact><Email>sobral@vt.edu</Email><URL>http://www.vbi.vt.edu</URL></Contact></Author><Affiliation ID="Aff21"><OrgName>Virginia Bioinformatics Institute at Virginia Tech (0477)</OrgName><OrgAddress><City>Blacksburg</City><State>VA</State><Postcode>92024</Postcode><Country>USA</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para>The application of new information and biotechnologies to infectious disease research provides an opportunity to design, develop and deploy a comprehensive cyberinfrastructure for life sciences. The application of integrative approaches including theory, wet experimentation, modeling and simulation and the leveraging of a strong comparative, evolutionary framework has spawned pathosystems biology. I will show examples of how cyberinfrastructure is being developed and used to support pathosystems biology.</Para></Abstract></ChapterHeader><NoBody></NoBody></Chapter></Part></Book></Series></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Cyberinfrastructure for PathoSystems Biology</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Cyberinfrastructure for PathoSystems Biology</title></titleInfo><name type="personal"><namePart type="given">Bruno</namePart><namePart type="given">W.</namePart><namePart type="given">S.</namePart><namePart type="family">Sobral</namePart><affiliation>Virginia Bioinformatics Institute at Virginia Tech (0477), 92024, Blacksburg, VA, USA</affiliation><affiliation>E-mail: sobral@vt.edu</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="conference" displayLabel="OriginalPaper"></genre><originInfo><publisher>Springer Berlin Heidelberg</publisher><place><placeTerm type="text">Berlin, Heidelberg</placeTerm></place><dateIssued encoding="w3cdtf">2005</dateIssued><copyrightDate encoding="w3cdtf">2005</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Abstract: The application of new information and biotechnologies to infectious disease research provides an opportunity to design, develop and deploy a comprehensive cyberinfrastructure for life sciences. The application of integrative approaches including theory, wet experimentation, modeling and simulation and the leveraging of a strong comparative, evolutionary framework has spawned pathosystems biology. I will show examples of how cyberinfrastructure is being developed and used to support pathosystems biology.</abstract><relatedItem type="host"><titleInfo><title>Advances in Bioinformatics and Computational Biology</title><subTitle>Brazilian Symposium on Bioinformatics, BSB 2005, Sao Leopoldo, Brazil, July 27-29, 2005. Proceedings</subTitle></titleInfo><name type="personal"><namePart type="given">João</namePart><namePart type="given">Carlos</namePart><namePart type="family">Setubal</namePart><affiliation>Department of Computer Science, Virginia Bioinformatics Institute and Virginia Polytechnic Institute and State University, Bioinformatics 1, Box 0477, 24060-0477, Blacksburg, VA, USA</affiliation><affiliation>E-mail: setubal@vbi.vt.edu</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Sergio</namePart><namePart type="family">Verjovski-Almeida</namePart><affiliation>Instituto de Quimica, Departamento de Bioquimica, Universidade de Sao Paulo, Av. 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Robotics)</topic><topic authority="SpringerSubjectCodes" authorityURI="I16021">Algorithm Analysis and Problem Complexity</topic></subject><identifier type="DOI">10.1007/11532323</identifier><identifier type="ISBN">978-3-540-28008-8</identifier><identifier type="eISBN">978-3-540-31861-3</identifier><identifier type="ISSN">0302-9743</identifier><identifier type="eISSN">1611-3349</identifier><identifier type="BookTitleID">125602</identifier><identifier type="BookID">978-3-540-31861-3</identifier><identifier type="BookChapterCount">35</identifier><identifier type="BookVolumeNumber">3594</identifier><identifier type="BookSequenceNumber">3594</identifier><identifier type="PartChapterCount">4</identifier><part><date>2005</date><detail type="part"><title>Invited Papers</title></detail><detail type="volume"><number>3594</number><caption>vol.</caption></detail><extent unit="pages"><start>11</start><end>27</end></extent></part><recordInfo><recordOrigin>Springer-Verlag Berlin Heidelberg, 2005</recordOrigin></recordInfo></relatedItem><relatedItem type="series"><titleInfo><title>Lecture Notes in Computer Science</title></titleInfo><name type="personal"><namePart type="given">David</namePart><namePart type="family">Hutchison</namePart><affiliation>Lancaster University, UK</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Takeo</namePart><namePart type="family">Kanade</namePart><affiliation>Carnegie Mellon University, Pittsburgh, PA, USA</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Josef</namePart><namePart type="family">Kittler</namePart><affiliation>University of Surrey, Guildford, UK</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Jon</namePart><namePart type="given">M.</namePart><namePart type="family">Kleinberg</namePart><affiliation>Cornell University, Ithaca, NY, USA</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Friedemann</namePart><namePart type="family">Mattern</namePart><affiliation>ETH Zurich, Switzerland</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">John</namePart><namePart type="given">C.</namePart><namePart type="family">Mitchell</namePart><affiliation>Stanford University, CA, USA</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Moni</namePart><namePart type="family">Naor</namePart><affiliation>Weizmann Institute of Science, Rehovot, Israel</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Oscar</namePart><namePart type="family">Nierstrasz</namePart><affiliation>University of Bern, Switzerland</affiliation><role><roleTerm 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