Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase
Identifieur interne : 000E43 ( Istex/Corpus ); précédent : 000E42; suivant : 000E44Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase
Auteurs : Chung-Hoon Kim ; Hee-Dong Chae ; Jooryung Huh ; Byung-Moon Kang ; Yoon Seok Chang ; Joo-Hyun NamSource :
- Journal of Obstetrics and Gynaecology Research [ 1341-8076 ] ; 2002-08.
English descriptors
- Teeft :
- Aofog, Brain injury, Cerebral cortex, Control pups, Different routes, Ecmo, Endometrial, Endometrial thickness, Epithelial, Estrogen receptor, Extracorporeal membrane oxygenation, Fetal lambs, Gynaecology, Gynaecology research, Gynecology, Inos, Japan objective, Naoki nagata, Obstetrics, Oxygenated, Oxygenated blood, Oxygenated blood distribution, Preovulatory, Preovulatory phase, Progesterone, Progesterone receptor, Receptor, Receptor scores, Right atrium, Sgml, Sonographic, Stromal, Study design, Umbilical vein, Young scientist award, Younger physicians.
Abstract
Objectives: The purpose of the present study is to evaluate the relationship between endometrial concentrations of estrogen receptor (ER) and progesterone receptor (PR), and sonographic endometrial findings in the preovulatory phase of menstrual cycle. Study Design: In 45 cycles of 45 infertile women with tubal factor only, transvaginal sonographic assessments and biopsy for immunohistochemical staining of the endometrium were made in the preovulatory phase of unstimulated, normal menstrual cycle. Immunohistochemical localization of ER and PR was scored according to intensity of staining and proportion of cells specifically stained in glandular epithelium and stroma, and the results were analyzed according to the sonographic endometrial thickness (<6 mm, 6–10 mm, or >10 mm) and pattern. Endometrial patterns were classified as A, centrally hyperechogenic triple‐line pattem or non‐A, not triple‐line. Results: There were no significant differences in the endometrial thickness, serum estradiol level and serum progesterone level between A and non‐A groups. The receptor scores of epithelial and stromal ER and epithelial PR were comparable in A and non‐A groups. However, the receptor score of stromal PR was significantly higher in A group, with 4.8 ± 1.4 compared with 2.7 ± 1.7 in non‐A group (P < 0.001). There were no differences in the receptor scores of epithelial ER, epithelial PR, stromal ER and stromal PR among the 3 groups according to the endometrial thickness. Conclusions: This study suggests that high PR expression in endometrial stroma could be related to the sonographic triple‐line or multilayered pattern of endometrium in the preovulatory period.
Url:
DOI: 10.1046/j.1341-8076.2002.00048.x
Links to Exploration step
ISTEX:37A1693A00E83CA1D0EE7AD585F65175776EA372Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title><author><name sortKey="Kim, Chung Oon" sort="Kim, Chung Oon" uniqKey="Kim C" first="Chung-Hoon" last="Kim">Chung-Hoon Kim</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Chae, Hee Ong" sort="Chae, Hee Ong" uniqKey="Chae H" first="Hee-Dong" last="Chae">Hee-Dong Chae</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Huh, Jooryung" sort="Huh, Jooryung" uniqKey="Huh J" first="Jooryung" last="Huh">Jooryung Huh</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Kang, Byung Oon" sort="Kang, Byung Oon" uniqKey="Kang B" first="Byung-Moon" last="Kang">Byung-Moon Kang</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Chang, Yoon Seok" sort="Chang, Yoon Seok" uniqKey="Chang Y" first="Yoon Seok" last="Chang">Yoon Seok Chang</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Nam, Joo Yun" sort="Nam, Joo Yun" uniqKey="Nam J" first="Joo-Hyun" last="Nam">Joo-Hyun Nam</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:37A1693A00E83CA1D0EE7AD585F65175776EA372</idno><date when="2002" year="2002">2002</date><idno type="doi">10.1046/j.1341-8076.2002.00048.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-5G3HQXHH-W/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000E43</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000E43</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title><author><name sortKey="Kim, Chung Oon" sort="Kim, Chung Oon" uniqKey="Kim C" first="Chung-Hoon" last="Kim">Chung-Hoon Kim</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Chae, Hee Ong" sort="Chae, Hee Ong" uniqKey="Chae H" first="Hee-Dong" last="Chae">Hee-Dong Chae</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Huh, Jooryung" sort="Huh, Jooryung" uniqKey="Huh J" first="Jooryung" last="Huh">Jooryung Huh</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Kang, Byung Oon" sort="Kang, Byung Oon" uniqKey="Kang B" first="Byung-Moon" last="Kang">Byung-Moon Kang</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Chang, Yoon Seok" sort="Chang, Yoon Seok" uniqKey="Chang Y" first="Yoon Seok" last="Chang">Yoon Seok Chang</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author><author><name sortKey="Nam, Joo Yun" sort="Nam, Joo Yun" uniqKey="Nam J" first="Joo-Hyun" last="Nam">Joo-Hyun Nam</name><affiliation><mods:affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Obstetrics and Gynaecology Research</title><title level="j" type="alt">JOURNAL OF OBSTETRICS GYNAECOLOGY RESEARCH</title><idno type="ISSN">1341-8076</idno><idno type="eISSN">1447-0756</idno><imprint><biblScope unit="vol">28</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="233">233</biblScope><biblScope unit="page" to="235">235</biblScope><publisher>Blackwell Science Asia Pty. Ltd.</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2002-08">2002-08</date></imprint><idno type="ISSN">1341-8076</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1341-8076</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Aofog</term><term>Brain injury</term><term>Cerebral cortex</term><term>Control pups</term><term>Different routes</term><term>Ecmo</term><term>Endometrial</term><term>Endometrial thickness</term><term>Epithelial</term><term>Estrogen receptor</term><term>Extracorporeal membrane oxygenation</term><term>Fetal lambs</term><term>Gynaecology</term><term>Gynaecology research</term><term>Gynecology</term><term>Inos</term><term>Japan objective</term><term>Naoki nagata</term><term>Obstetrics</term><term>Oxygenated</term><term>Oxygenated blood</term><term>Oxygenated blood distribution</term><term>Preovulatory</term><term>Preovulatory phase</term><term>Progesterone</term><term>Progesterone receptor</term><term>Receptor</term><term>Receptor scores</term><term>Right atrium</term><term>Sgml</term><term>Sonographic</term><term>Stromal</term><term>Study design</term><term>Umbilical vein</term><term>Young scientist award</term><term>Younger physicians</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objectives: The purpose of the present study is to evaluate the relationship between endometrial concentrations of estrogen receptor (ER) and progesterone receptor (PR), and sonographic endometrial findings in the preovulatory phase of menstrual cycle. Study Design: In 45 cycles of 45 infertile women with tubal factor only, transvaginal sonographic assessments and biopsy for immunohistochemical staining of the endometrium were made in the preovulatory phase of unstimulated, normal menstrual cycle. Immunohistochemical localization of ER and PR was scored according to intensity of staining and proportion of cells specifically stained in glandular epithelium and stroma, and the results were analyzed according to the sonographic endometrial thickness (<6 mm, 6–10 mm, or >10 mm) and pattern. Endometrial patterns were classified as A, centrally hyperechogenic triple‐line pattem or non‐A, not triple‐line. Results: There were no significant differences in the endometrial thickness, serum estradiol level and serum progesterone level between A and non‐A groups. The receptor scores of epithelial and stromal ER and epithelial PR were comparable in A and non‐A groups. However, the receptor score of stromal PR was significantly higher in A group, with 4.8 ± 1.4 compared with 2.7 ± 1.7 in non‐A group (P < 0.001). There were no differences in the receptor scores of epithelial ER, epithelial PR, stromal ER and stromal PR among the 3 groups according to the endometrial thickness. Conclusions: This study suggests that high PR expression in endometrial stroma could be related to the sonographic triple‐line or multilayered pattern of endometrium in the preovulatory period.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>endometrial</json:string><json:string>young scientist award</json:string><json:string>obstetrics</json:string><json:string>receptor</json:string><json:string>inos</json:string><json:string>ecmo</json:string><json:string>aofog</json:string><json:string>oxygenated</json:string><json:string>sonographic</json:string><json:string>gynecology</json:string><json:string>gynaecology</json:string><json:string>epithelial</json:string><json:string>stromal</json:string><json:string>preovulatory</json:string><json:string>progesterone</json:string><json:string>sgml</json:string><json:string>cerebral cortex</json:string><json:string>preovulatory phase</json:string><json:string>brain injury</json:string><json:string>oxygenated blood</json:string><json:string>extracorporeal membrane oxygenation</json:string><json:string>endometrial thickness</json:string><json:string>fetal lambs</json:string><json:string>right atrium</json:string><json:string>study design</json:string><json:string>umbilical vein</json:string><json:string>control pups</json:string><json:string>gynaecology research</json:string><json:string>younger physicians</json:string><json:string>different routes</json:string><json:string>estrogen receptor</json:string><json:string>progesterone receptor</json:string><json:string>oxygenated blood distribution</json:string><json:string>naoki nagata</json:string><json:string>japan objective</json:string><json:string>receptor scores</json:string></teeft></keywords><author><json:item><name>Chung‐hoon Kim</name><affiliations><json:string>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Hee‐Dong Chae</name><affiliations><json:string>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Jooryung Huh</name><affiliations><json:string>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Byung‐Moon Kang</name><affiliations><json:string>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Yoon Seok Chang</name><affiliations><json:string>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</json:string></affiliations></json:item><json:item><name>Joo‐Hyun Nam</name><affiliations><json:string>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>endometrial pattern</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>endometrial thickness</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>estrogen receptor (ER)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>progesterone receptor (PR)</value></json:item></subject><articleId><json:string>JOG0482</json:string></articleId><arkIstex>ark:/67375/WNG-5G3HQXHH-W</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Objectives: The purpose of the present study is to evaluate the relationship between endometrial concentrations of estrogen receptor (ER) and progesterone receptor (PR), and sonographic endometrial findings in the preovulatory phase of menstrual cycle. Study Design: In 45 cycles of 45 infertile women with tubal factor only, transvaginal sonographic assessments and biopsy for immunohistochemical staining of the endometrium were made in the preovulatory phase of unstimulated, normal menstrual cycle. Immunohistochemical localization of ER and PR was scored according to intensity of staining and proportion of cells specifically stained in glandular epithelium and stroma, and the results were analyzed according to the sonographic endometrial thickness (>6 mm, 6–10 mm, or >10 mm) and pattern. Endometrial patterns were classified as A, centrally hyperechogenic triple‐line pattem or non‐A, not triple‐line. Results: There were no significant differences in the endometrial thickness, serum estradiol level and serum progesterone level between A and non‐A groups. The receptor scores of epithelial and stromal ER and epithelial PR were comparable in A and non‐A groups. However, the receptor score of stromal PR was significantly higher in A group, with 4.8 ± 1.4 compared with 2.7 ± 1.7 in non‐A group (P > 0.001). There were no differences in the receptor scores of epithelial ER, epithelial PR, stromal ER and stromal PR among the 3 groups according to the endometrial thickness. Conclusions: This study suggests that high PR expression in endometrial stroma could be related to the sonographic triple‐line or multilayered pattern of endometrium in the preovulatory period.</abstract><qualityIndicators><score>5.974</score><pdfWordCount>1106</pdfWordCount><pdfCharCount>7176</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>3</pdfPageCount><pdfPageSize>595 x 842 pts (A4)</pdfPageSize><refBibsNative>false</refBibsNative><abstractWordCount>239</abstractWordCount><abstractCharCount>1684</abstractCharCount><keywordCount>4</keywordCount></qualityIndicators><title>Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title><genre><json:string>article</json:string></genre><host><title>Journal of Obstetrics and Gynaecology Research</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1447-0756</json:string></doi><issn><json:string>1341-8076</json:string></issn><eissn><json:string>1447-0756</json:string></eissn><publisherId><json:string>JOG</json:string></publisherId><volume>28</volume><issue>4</issue><pages><first>233</first><last>235</last></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date></date><geogName></geogName><orgName></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName></persName><placeName></placeName><ref_url></ref_url><ref_bibl></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-5G3HQXHH-W</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - obstetrics & gynecology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - obstetrics & reproductive medicine</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Obstetrics and Gynaecology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>2002</publicationDate><copyrightDate>2002</copyrightDate><doi><json:string>10.1046/j.1341-8076.2002.00048.x</json:string></doi><id>37A1693A00E83CA1D0EE7AD585F65175776EA372</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-5G3HQXHH-W/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-5G3HQXHH-W/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/WNG-5G3HQXHH-W/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Science Asia Pty. Ltd.</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2002-08"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title><title level="a" type="sub">2000; 26: 95–101</title><title level="a" type="short">Young Scientist Award</title><author xml:id="author-0000"><persName><forename type="first">Chung‐hoon</forename><surname>Kim</surname></persName><affiliation><orgName type="department">Department of Obstetrics and Gynecology</orgName><address><addrLine>College of Medicine</addrLine><addrLine>University of Ulsan</addrLine><addrLine>Asan Medical Center</addrLine><addrLine>Seoul</addrLine><country key="KR">KOREA, REPUBLIC OF</country><country key="KR"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Hee‐Dong</forename><surname>Chae</surname></persName><affiliation><orgName type="department">Department of Obstetrics and Gynecology</orgName><address><addrLine>College of Medicine</addrLine><addrLine>University of Ulsan</addrLine><addrLine>Asan Medical Center</addrLine><addrLine>Seoul</addrLine><country key="KR">KOREA, REPUBLIC OF</country><country key="KR"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Jooryung</forename><surname>Huh</surname></persName><affiliation><orgName type="department">Department of Obstetrics and Gynecology</orgName><address><addrLine>College of Medicine</addrLine><addrLine>University of Ulsan</addrLine><addrLine>Asan Medical Center</addrLine><addrLine>Seoul</addrLine><country key="KR">KOREA, REPUBLIC OF</country><country key="KR"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Byung‐Moon</forename><surname>Kang</surname></persName><affiliation><orgName type="department">Department of Obstetrics and Gynecology</orgName><address><addrLine>College of Medicine</addrLine><addrLine>University of Ulsan</addrLine><addrLine>Asan Medical Center</addrLine><addrLine>Seoul</addrLine><country key="KR">KOREA, REPUBLIC OF</country><country key="KR"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Yoon Seok</forename><surname>Chang</surname></persName><affiliation><orgName type="department">Department of Obstetrics and Gynecology</orgName><address><addrLine>College of Medicine</addrLine><addrLine>University of Ulsan</addrLine><addrLine>Asan Medical Center</addrLine><addrLine>Seoul</addrLine><country key="KR">KOREA, REPUBLIC OF</country><country key="KR"></country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">Joo‐Hyun</forename><surname>Nam</surname></persName><affiliation><orgName type="department">Department of Obstetrics and Gynecology</orgName><address><addrLine>College of Medicine</addrLine><addrLine>University of Ulsan</addrLine><addrLine>Asan Medical Center</addrLine><addrLine>Seoul</addrLine><country key="KR">KOREA, REPUBLIC OF</country><country key="KR"></country></address></affiliation></author><idno type="istex">37A1693A00E83CA1D0EE7AD585F65175776EA372</idno><idno type="ark">ark:/67375/WNG-5G3HQXHH-W</idno><idno type="DOI">10.1046/j.1341-8076.2002.00048.x</idno><idno type="unit">JOG0482</idno><idno type="toTypesetVersion">file:JOG.JOG482.pdf</idno></analytic><monogr><title level="j" type="main">Journal of Obstetrics and Gynaecology Research</title><title level="j" type="alt">JOURNAL OF OBSTETRICS GYNAECOLOGY RESEARCH</title><idno type="pISSN">1341-8076</idno><idno type="eISSN">1447-0756</idno><idno type="book-DOI">10.1111/(ISSN)1447-0756</idno><idno type="book-part-DOI">10.1111/jog.2002.28.issue-4</idno><idno type="product">JOG</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">28</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="233">233</biblScope><biblScope unit="page" to="235">235</biblScope><publisher>Blackwell Science Asia Pty. Ltd.</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2002-08"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><p><hi rend="italic"><hi rend="italic">Objectives:</hi></hi> The purpose of the present study is to evaluate the relationship between endometrial concentrations of estrogen receptor (ER) and progesterone receptor (PR), and sonographic endometrial findings in the preovulatory phase of menstrual cycle.</p><p><hi rend="italic"><hi rend="italic">Study Design:</hi></hi> In 45 cycles of 45 infertile women with tubal factor only, transvaginal sonographic assessments and biopsy for immunohistochemical staining of the endometrium were made in the preovulatory phase of unstimulated, normal menstrual cycle. Immunohistochemical localization of ER and PR was scored according to intensity of staining and proportion of cells specifically stained in glandular epithelium and stroma, and the results were analyzed according to the sonographic endometrial thickness (<6 mm, 6–10 mm, or >10 mm) and pattern. Endometrial patterns were classified as A, centrally hyperechogenic triple‐line pattem or non‐A, not triple‐line.</p><p><hi rend="italic"><hi rend="italic">Results:</hi></hi> There were no significant differences in the endometrial thickness, serum estradiol level and serum progesterone level between A and non‐A groups. The receptor scores of epithelial and stromal ER and epithelial PR were comparable in A and non‐A groups. However, the receptor score of stromal PR was significantly higher in A group, with 4.8 ± 1.4 compared with 2.7 ± 1.7 in non‐A group (<hi rend="italic">P</hi> < 0.001). There were no differences in the receptor scores of epithelial ER, epithelial PR, stromal ER and stromal PR among the 3 groups according to the endometrial thickness.</p><p><hi rend="italic"><hi rend="italic">Conclusions:</hi></hi> This study suggests that high PR expression in endometrial stroma could be related to the sonographic triple‐line or multilayered pattern of endometrium in the preovulatory period.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1">endometrial pattern</term><term xml:id="k2">endometrial thickness</term><term xml:id="k3">estrogen receptor (ER)</term><term xml:id="k4">progesterone receptor (PR)</term></keywords><keywords rend="tocHeading1"><term>Miscellaneous</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change xml:id="refBibs-istex" who="#ISTEX-API" when="2018-06-14">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-5G3HQXHH-W/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley component found"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Science Asia Pty. Ltd.</publisherName><publisherLoc>Melbourne, Australia</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1447-0756</doi><issn type="print">1341-8076</issn><issn type="electronic">1447-0756</issn><idGroup><id type="product" value="JOG"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="JOURNAL OF OBSTETRICS GYNAECOLOGY RESEARCH">Journal of Obstetrics and Gynaecology Research</title></titleGroup></publicationMeta><publicationMeta level="part" position="08004"><doi origin="wiley">10.1111/jog.2002.28.issue-4</doi><numberingGroup><numbering type="journalVolume" number="28">28</numbering><numbering type="journalIssue" number="4">4</numbering></numberingGroup><coverDate startDate="2002-08">August 2002</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0023300" status="forIssue"><doi origin="wiley">10.1046/j.1341-8076.2002.00048.x</doi><idGroup><id type="unit" value="JOG0482"></id></idGroup><titleGroup><title type="tocHeading1">Miscellaneous</title></titleGroup><eventGroup><event type="firstOnline" date="2008-10-01"></event><event type="publishedOnlineFinalForm" date="2008-10-01"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:Header result:Header" date="2010-03-05"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-01"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-30"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="233">233</numbering><numbering type="pageLast" number="235">235</numbering></numberingGroup><linkGroup><link type="toTypesetVersion" href="file:JOG.JOG482.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="0"></count><count type="formulaTotal" number="0"></count><count type="referenceTotal" number="0"></count><count type="wordTotal" number="1068"></count><count type="linksPubMed" number="0"></count><count type="linksCrossRef" number="0"></count></countGroup><titleGroup><title type="main">Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title><title type="subtitle">2000; 26: 95–101</title><title type="shortAuthors">Young Scientist Award</title><title type="short">Young Scientist Award</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#aff-1-1"><personName><givenNames>Chung‐hoon</givenNames><familyName>Kim</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#aff-1-1"><personName><givenNames>Hee‐Dong</givenNames><familyName>Chae</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#aff-1-1"><personName><givenNames>Jooryung</givenNames><familyName>Huh</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#aff-1-1"><personName><givenNames>Byung‐Moon</givenNames><familyName>Kang</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#aff-1-1"><personName><givenNames>Yoon Seok</givenNames><familyName>Chang</familyName></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#aff-1-1"><personName><givenNames>Joo‐Hyun</givenNames><familyName>Nam</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="aff-1-1" countryCode="KR"><unparsedAffiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">endometrial pattern</keyword><keyword xml:id="k2">endometrial thickness</keyword><keyword xml:id="k3">estrogen receptor (ER)</keyword><keyword xml:id="k4">progesterone receptor (PR)</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p> <i><b>Objectives:</b></i> The purpose of the present study is to evaluate the relationship between endometrial concentrations of estrogen receptor (ER) and progesterone receptor (PR), and sonographic endometrial findings in the preovulatory phase of menstrual cycle.</p><p> <i><b>Study Design:</b></i> In 45 cycles of 45 infertile women with tubal factor only, transvaginal sonographic assessments and biopsy for immunohistochemical staining of the endometrium were made in the preovulatory phase of unstimulated, normal menstrual cycle. Immunohistochemical localization of ER and PR was scored according to intensity of staining and proportion of cells specifically stained in glandular epithelium and stroma, and the results were analyzed according to the sonographic endometrial thickness (<6 mm, 6–10 mm, or >10 mm) and pattern. Endometrial patterns were classified as A, centrally hyperechogenic triple‐line pattem or non‐A, not triple‐line.</p><p> <i><b>Results:</b></i> There were no significant differences in the endometrial thickness, serum estradiol level and serum progesterone level between A and non‐A groups. The receptor scores of epithelial and stromal ER and epithelial PR were comparable in A and non‐A groups. However, the receptor score of stromal PR was significantly higher in A group, with 4.8 ± 1.4 compared with 2.7 ± 1.7 in non‐A group (<i>P</i> < 0.001). There were no differences in the receptor scores of epithelial ER, epithelial PR, stromal ER and stromal PR among the 3 groups according to the endometrial thickness.</p><p> <i><b>Conclusions:</b></i> This study suggests that high PR expression in endometrial stroma could be related to the sonographic triple‐line or multilayered pattern of endometrium in the preovulatory period.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title><subTitle>2000; 26: 95–101</subTitle></titleInfo><titleInfo type="abbreviated" lang="en"><title>Young Scientist Award</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase</title></titleInfo><name type="personal"><namePart type="given">Chung‐hoon</namePart><namePart type="family">Kim</namePart><affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hee‐Dong</namePart><namePart type="family">Chae</namePart><affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jooryung</namePart><namePart type="family">Huh</namePart><affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Byung‐Moon</namePart><namePart type="family">Kang</namePart><affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yoon Seok</namePart><namePart type="family">Chang</namePart><affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Joo‐Hyun</namePart><namePart type="family">Nam</namePart><affiliation>Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Science Asia Pty. Ltd.</publisher><place><placeTerm type="text">Melbourne, Australia</placeTerm></place><dateIssued encoding="w3cdtf">2002-08</dateIssued><copyrightDate encoding="w3cdtf">2002</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">0</extent><extent unit="tables">0</extent><extent unit="formulas">0</extent><extent unit="references">0</extent><extent unit="linksCrossRef">0</extent><extent unit="words">1068</extent></physicalDescription><abstract lang="en">Objectives: The purpose of the present study is to evaluate the relationship between endometrial concentrations of estrogen receptor (ER) and progesterone receptor (PR), and sonographic endometrial findings in the preovulatory phase of menstrual cycle. Study Design: In 45 cycles of 45 infertile women with tubal factor only, transvaginal sonographic assessments and biopsy for immunohistochemical staining of the endometrium were made in the preovulatory phase of unstimulated, normal menstrual cycle. Immunohistochemical localization of ER and PR was scored according to intensity of staining and proportion of cells specifically stained in glandular epithelium and stroma, and the results were analyzed according to the sonographic endometrial thickness (<6 mm, 6–10 mm, or >10 mm) and pattern. Endometrial patterns were classified as A, centrally hyperechogenic triple‐line pattem or non‐A, not triple‐line. Results: There were no significant differences in the endometrial thickness, serum estradiol level and serum progesterone level between A and non‐A groups. The receptor scores of epithelial and stromal ER and epithelial PR were comparable in A and non‐A groups. However, the receptor score of stromal PR was significantly higher in A group, with 4.8 ± 1.4 compared with 2.7 ± 1.7 in non‐A group (P < 0.001). There were no differences in the receptor scores of epithelial ER, epithelial PR, stromal ER and stromal PR among the 3 groups according to the endometrial thickness. Conclusions: This study suggests that high PR expression in endometrial stroma could be related to the sonographic triple‐line or multilayered pattern of endometrium in the preovulatory period.</abstract><subject lang="en"><genre>keywords</genre><topic>endometrial pattern</topic><topic>endometrial thickness</topic><topic>estrogen receptor (ER)</topic><topic>progesterone receptor (PR)</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Obstetrics and Gynaecology Research</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">1341-8076</identifier><identifier type="eISSN">1447-0756</identifier><identifier type="DOI">10.1111/(ISSN)1447-0756</identifier><identifier type="PublisherID">JOG</identifier><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>28</number></detail><detail type="issue"><caption>no.</caption><number>4</number></detail><extent unit="pages"><start>233</start><end>235</end></extent></part></relatedItem><identifier type="istex">37A1693A00E83CA1D0EE7AD585F65175776EA372</identifier><identifier type="ark">ark:/67375/WNG-5G3HQXHH-W</identifier><identifier type="DOI">10.1046/j.1341-8076.2002.00048.x</identifier><identifier type="ArticleID">JOG0482</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Science Asia Pty. Ltd.</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-5G3HQXHH-W/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Informatique/explor/SgmlV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E43 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000E43 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Informatique
|area= SgmlV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:37A1693A00E83CA1D0EE7AD585F65175776EA372
|texte= Relationship between endometrial estrogen and progesterone receptors, and sonographic endometrial appearance in the preovulatory phase
}}
| This area was generated with Dilib version V0.6.33. |  |