Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses.
Identifieur interne : 001F63 ( PubMed/Curation ); précédent : 001F62; suivant : 001F64Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses.
Auteurs : D G Kent [États-Unis] ; Q. Peng ; R T Isaacs ; S B Whiteside ; D L Barker ; D J AppleSource :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 1998.
English descriptors
- KwdEn :
- Animals, Biomechanical Phenomena, Capsulorhexis, Cell Division, Epithelial Cells (pathology), Lens Capsule, Crystalline (pathology), Lens Capsule, Crystalline (surgery), Lens Implantation, Intraocular (methods), Lenses, Intraocular, Male, Prosthesis Design, Rabbits, Silicone Elastomers, Suture Techniques.
- MESH :
- chemical : Silicone Elastomers.
- methods : Lens Implantation, Intraocular.
- pathology : Epithelial Cells, Lens Capsule, Crystalline.
- surgery : Lens Capsule, Crystalline.
- Animals, Biomechanical Phenomena, Capsulorhexis, Cell Division, Lenses, Intraocular, Male, Prosthesis Design, Rabbits, Suture Techniques.
Abstract
To evaluate the effects of a new mini-haptic design on the strength and stability of capsular bag fixation of plate-haptic silicone intraocular lenses (IOLs) and determine whether this design encourages the growth of regenerating lens material or fibrous tissue around the haptic biomaterial and thus improves lens fixation in the capsular bag.
PubMed: 9610451
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pubmed:9610451Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses.</title>
<author><name sortKey="Kent, D G" sort="Kent, D G" uniqKey="Kent D" first="D G" last="Kent">D G Kent</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston 29425-2236, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston 29425-2236</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peng, Q" sort="Peng, Q" uniqKey="Peng Q" first="Q" last="Peng">Q. Peng</name>
</author>
<author><name sortKey="Isaacs, R T" sort="Isaacs, R T" uniqKey="Isaacs R" first="R T" last="Isaacs">R T Isaacs</name>
</author>
<author><name sortKey="Whiteside, S B" sort="Whiteside, S B" uniqKey="Whiteside S" first="S B" last="Whiteside">S B Whiteside</name>
</author>
<author><name sortKey="Barker, D L" sort="Barker, D L" uniqKey="Barker D" first="D L" last="Barker">D L Barker</name>
</author>
<author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D J" last="Apple">D J Apple</name>
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<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1998">1998</date>
<idno type="RBID">pubmed:9610451</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses.</title>
<author><name sortKey="Kent, D G" sort="Kent, D G" uniqKey="Kent D" first="D G" last="Kent">D G Kent</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston 29425-2236, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston 29425-2236</wicri:regionArea>
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</author>
<author><name sortKey="Peng, Q" sort="Peng, Q" uniqKey="Peng Q" first="Q" last="Peng">Q. Peng</name>
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<author><name sortKey="Isaacs, R T" sort="Isaacs, R T" uniqKey="Isaacs R" first="R T" last="Isaacs">R T Isaacs</name>
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<author><name sortKey="Whiteside, S B" sort="Whiteside, S B" uniqKey="Whiteside S" first="S B" last="Whiteside">S B Whiteside</name>
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<author><name sortKey="Barker, D L" sort="Barker, D L" uniqKey="Barker D" first="D L" last="Barker">D L Barker</name>
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<author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D J" last="Apple">D J Apple</name>
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<series><title level="j">Journal of cataract and refractive surgery</title>
<idno type="ISSN">0886-3350</idno>
<imprint><date when="1998" type="published">1998</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Biomechanical Phenomena</term>
<term>Capsulorhexis</term>
<term>Cell Division</term>
<term>Epithelial Cells (pathology)</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Capsule, Crystalline (surgery)</term>
<term>Lens Implantation, Intraocular (methods)</term>
<term>Lenses, Intraocular</term>
<term>Male</term>
<term>Prosthesis Design</term>
<term>Rabbits</term>
<term>Silicone Elastomers</term>
<term>Suture Techniques</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Silicone Elastomers</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Lens Implantation, Intraocular</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Epithelial Cells</term>
<term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Biomechanical Phenomena</term>
<term>Capsulorhexis</term>
<term>Cell Division</term>
<term>Lenses, Intraocular</term>
<term>Male</term>
<term>Prosthesis Design</term>
<term>Rabbits</term>
<term>Suture Techniques</term>
</keywords>
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<front><div type="abstract" xml:lang="en">To evaluate the effects of a new mini-haptic design on the strength and stability of capsular bag fixation of plate-haptic silicone intraocular lenses (IOLs) and determine whether this design encourages the growth of regenerating lens material or fibrous tissue around the haptic biomaterial and thus improves lens fixation in the capsular bag.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">9610451</PMID>
<DateCreated><Year>1998</Year>
<Month>07</Month>
<Day>09</Day>
</DateCreated>
<DateCompleted><Year>1998</Year>
<Month>07</Month>
<Day>09</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0886-3350</ISSN>
<JournalIssue CitedMedium="Print"><Volume>24</Volume>
<Issue>5</Issue>
<PubDate><Year>1998</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Journal of cataract and refractive surgery</Title>
<ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation>
</Journal>
<ArticleTitle>Mini-haptics to improve capsular fixation of plate-haptic silicone intraocular lenses.</ArticleTitle>
<Pagination><MedlinePgn>666-71</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To evaluate the effects of a new mini-haptic design on the strength and stability of capsular bag fixation of plate-haptic silicone intraocular lenses (IOLs) and determine whether this design encourages the growth of regenerating lens material or fibrous tissue around the haptic biomaterial and thus improves lens fixation in the capsular bag.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Department of Ophthalmology, Charleston, South Carolina, USA.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Six rabbits had bilateral continuous curvilinear capsulorhexis, phacoemulsification, and plate-haptic silicone IOL implantation. Each rabbit had a small-hole plate IOL (Chiron C10UB) implanted in the right eye and a mini-haptic plate IOL (Chiron C40UB) in the left eye. All rabbits were killed at 2 months. The force required to extract one haptic from the capsular bag was measured with a digital force gauge. Histopathologic analysis was performed on all specimens.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The mini-haptic style IOLs required significantly more extraction force than the small-hole design (P = .011). Histopathologically, proliferating lens epithelial cells were observed growing circumferentially around the mini-haptics, causing a 360 degree synechia formation. This formation did not occur with the conventional small-hole plate IOLs used as the control.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Lens epithelial cell proliferation around the mini-haptics significantly improved capsular bag fixation of the plate-haptic silicone IOL. This should decrease the incidence of clinical decentration and dislocation.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kent</LastName>
<ForeName>D G</ForeName>
<Initials>DG</Initials>
<AffiliationInfo><Affiliation>Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston 29425-2236, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Peng</LastName>
<ForeName>Q</ForeName>
<Initials>Q</Initials>
</Author>
<Author ValidYN="Y"><LastName>Isaacs</LastName>
<ForeName>R T</ForeName>
<Initials>RT</Initials>
</Author>
<Author ValidYN="Y"><LastName>Whiteside</LastName>
<ForeName>S B</ForeName>
<Initials>SB</Initials>
</Author>
<Author ValidYN="Y"><LastName>Barker</LastName>
<ForeName>D L</ForeName>
<Initials>DL</Initials>
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<Author ValidYN="Y"><LastName>Apple</LastName>
<ForeName>D J</ForeName>
<Initials>DJ</Initials>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<MedlineJournalInfo><Country>UNITED STATES</Country>
<MedlineTA>J Cataract Refract Surg</MedlineTA>
<NlmUniqueID>8604171</NlmUniqueID>
<ISSNLinking>0886-3350</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012826">Silicone Elastomers</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001696">Biomechanical Phenomena</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019923">Capsulorhexis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002455">Cell Division</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004847">Epithelial Cells</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007903">Lens Capsule, Crystalline</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019654">Lens Implantation, Intraocular</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D007910">Lenses, Intraocular</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011817">Rabbits</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D012826">Silicone Elastomers</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D013536">Suture Techniques</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
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