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Open radical retropubic prostatectomy using high anterior release of the levator fascia and constant haptic feedback in bilateral neurovascular bundle preservation plus early postoperative phosphodiesterase type 5 inhibition: a contemporary series.

Identifieur interne : 000D66 ( PubMed/Curation ); précédent : 000D65; suivant : 000D67

Open radical retropubic prostatectomy using high anterior release of the levator fascia and constant haptic feedback in bilateral neurovascular bundle preservation plus early postoperative phosphodiesterase type 5 inhibition: a contemporary series.

Auteurs : J Mikel Hubanks [États-Unis] ; Eric C. Umbreit ; R Jeffrey Karnes ; Robert P. Myers

Source :

RBID : pubmed:22154730

English descriptors

Abstract

Patients with newly diagnosed localized prostate cancer who choose surgery want cure and decent quality of life, namely, pad-free urinary control and, often, erectile function satisfactory for sexual intercourse.

DOI: 10.1016/j.eururo.2011.11.046
PubMed: 22154730

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pubmed:22154730

Le document en format XML

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<title xml:lang="en">Open radical retropubic prostatectomy using high anterior release of the levator fascia and constant haptic feedback in bilateral neurovascular bundle preservation plus early postoperative phosphodiesterase type 5 inhibition: a contemporary series.</title>
<author>
<name sortKey="Hubanks, J Mikel" sort="Hubanks, J Mikel" uniqKey="Hubanks J" first="J Mikel" last="Hubanks">J Mikel Hubanks</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Urology, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Urology, Mayo Clinic, Rochester, MN</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Umbreit, Eric C" sort="Umbreit, Eric C" uniqKey="Umbreit E" first="Eric C" last="Umbreit">Eric C. Umbreit</name>
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<author>
<name sortKey="Karnes, R Jeffrey" sort="Karnes, R Jeffrey" uniqKey="Karnes R" first="R Jeffrey" last="Karnes">R Jeffrey Karnes</name>
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<author>
<name sortKey="Myers, Robert P" sort="Myers, Robert P" uniqKey="Myers R" first="Robert P" last="Myers">Robert P. Myers</name>
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<title xml:lang="en">Open radical retropubic prostatectomy using high anterior release of the levator fascia and constant haptic feedback in bilateral neurovascular bundle preservation plus early postoperative phosphodiesterase type 5 inhibition: a contemporary series.</title>
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<name sortKey="Hubanks, J Mikel" sort="Hubanks, J Mikel" uniqKey="Hubanks J" first="J Mikel" last="Hubanks">J Mikel Hubanks</name>
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<nlm:affiliation>Department of Urology, Mayo Clinic, Rochester, MN, USA.</nlm:affiliation>
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<name sortKey="Karnes, R Jeffrey" sort="Karnes, R Jeffrey" uniqKey="Karnes R" first="R Jeffrey" last="Karnes">R Jeffrey Karnes</name>
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<name sortKey="Myers, Robert P" sort="Myers, Robert P" uniqKey="Myers R" first="Robert P" last="Myers">Robert P. Myers</name>
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<title level="j">European urology</title>
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<term>Adult</term>
<term>Aged</term>
<term>Carbolines (therapeutic use)</term>
<term>Coitus</term>
<term>Erectile Dysfunction (drug therapy)</term>
<term>Erectile Dysfunction (prevention & control)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Grading</term>
<term>Phosphodiesterase 5 Inhibitors (therapeutic use)</term>
<term>Prospective Studies</term>
<term>Prostate (drug effects)</term>
<term>Prostate (innervation)</term>
<term>Prostate (surgery)</term>
<term>Prostate-Specific Antigen (blood)</term>
<term>Prostatectomy (methods)</term>
<term>Prostatic Neoplasms (surgery)</term>
<term>Quality of Life</term>
<term>Surveys and Questionnaires</term>
<term>Tadalafil</term>
<term>Treatment Outcome</term>
<term>Urinary Incontinence (prevention & control)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en">
<term>Prostate-Specific Antigen</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Carbolines</term>
<term>Phosphodiesterase 5 Inhibitors</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>Erectile Dysfunction</term>
</keywords>
<keywords scheme="MESH" qualifier="innervation" xml:lang="en">
<term>Prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Prostatectomy</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en">
<term>Erectile Dysfunction</term>
<term>Urinary Incontinence</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Prostate</term>
<term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Coitus</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Grading</term>
<term>Prospective Studies</term>
<term>Quality of Life</term>
<term>Surveys and Questionnaires</term>
<term>Tadalafil</term>
<term>Treatment Outcome</term>
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<front>
<div type="abstract" xml:lang="en">Patients with newly diagnosed localized prostate cancer who choose surgery want cure and decent quality of life, namely, pad-free urinary control and, often, erectile function satisfactory for sexual intercourse.</div>
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<PMID Version="1">22154730</PMID>
<DateCreated>
<Year>2012</Year>
<Month>04</Month>
<Day>03</Day>
</DateCreated>
<DateCompleted>
<Year>2012</Year>
<Month>08</Month>
<Day>02</Day>
</DateCompleted>
<DateRevised>
<Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1873-7560</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>61</Volume>
<Issue>5</Issue>
<PubDate>
<Year>2012</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>European urology</Title>
<ISOAbbreviation>Eur. Urol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Open radical retropubic prostatectomy using high anterior release of the levator fascia and constant haptic feedback in bilateral neurovascular bundle preservation plus early postoperative phosphodiesterase type 5 inhibition: a contemporary series.</ArticleTitle>
<Pagination>
<MedlinePgn>878-84</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.eururo.2011.11.046</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Patients with newly diagnosed localized prostate cancer who choose surgery want cure and decent quality of life, namely, pad-free urinary control and, often, erectile function satisfactory for sexual intercourse.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Determine in a prospective study the positive surgical margin rate and functional outcomes for a consecutive series of patients undergoing open radical retropubic prostatectomy (ORRP) with bilateral neurovascular bundle preservation (BNVBP) performed by one experienced surgeon.</AbstractText>
<AbstractText Label="DESIGN, SETTING, AND PARTICIPANTS" NlmCategory="METHODS">Of 197 consecutive patients undergoing BNVBP during 2008, 123 were evaluable, allowing both immediate postoperative phosphodiesterase type 5 inhibition (PDE5i) and a third-party questionnaire with validated urinary and erectile function domains provided preoperatively and at 3, 6, and 12 mo postoperatively.</AbstractText>
<AbstractText Label="INTERVENTION" NlmCategory="METHODS">Two interventions were used: (1) ORRP with ×4.3 optical loupes and constant digital tactile monitoring during BNVBP preceded by high anterior release (HAR) of levator fascia and neurovascular bundles and (2) early postoperative PDE5i.</AbstractText>
<AbstractText Label="MEASUREMENTS" NlmCategory="METHODS">Age; biopsy Gleason score; clinical stage; preoperative prostate-specific antigen level; pathologic grade; stage; margin status; University of California, Los Angeles Prostate Cancer Index domain for urinary pad use and bother; and International Index of Erectile Function-5 (IIEF-5) were used.</AbstractText>
<AbstractText Label="RESULTS AND LIMITATIONS" NlmCategory="CONCLUSIONS">Surgical margins were positive in 1 of the 123 evaluable patients (1%). At 1 yr, 95% of patients were pad-free. Satisfactory erectile function was achieved by 109 patients (89%): 82 (67%) scored an IIEF-5 of 22-25, and 27 (22%) scored <22-25 with ≥4 on either satisfaction or confidence questions or achieved "full" erection within the first year. Mean hospital stay was 1.3 d. Limitations were (1) observational, noncomparative, single-surgeon series and (2) in third-party methodology, failure to capture patient answers for all questionnaire intervals with resultant inability to address durability of functional results for all patients.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">ORRP using ×4.3 optical loupe magnification, constant haptic feedback in BNVBP with HAR, and immediate postoperative PDE5i yielded satisfactory outcomes.</AbstractText>
<CopyrightInformation>Copyright © 2011 European Association of Urology. Published by Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
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<LastName>Hubanks</LastName>
<ForeName>J Mikel</ForeName>
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<LastName>Karnes</LastName>
<ForeName>R Jeffrey</ForeName>
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<ForeName>Robert P</ForeName>
<Initials>RP</Initials>
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<Language>eng</Language>
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<PublicationType UI="D016428">Journal Article</PublicationType>
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<ArticleDate DateType="Electronic">
<Year>2011</Year>
<Month>12</Month>
<Day>05</Day>
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<Country>Switzerland</Country>
<MedlineTA>Eur Urol</MedlineTA>
<NlmUniqueID>7512719</NlmUniqueID>
<ISSNLinking>0302-2838</ISSNLinking>
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<ChemicalList>
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<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D002243">Carbolines</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D058986">Phosphodiesterase 5 Inhibitors</NameOfSubstance>
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<Chemical>
<RegistryNumber>742SXX0ICT</RegistryNumber>
<NameOfSubstance UI="D000068581">Tadalafil</NameOfSubstance>
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<RegistryNumber>EC 3.4.21.77</RegistryNumber>
<NameOfSubstance UI="D017430">Prostate-Specific Antigen</NameOfSubstance>
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<CommentsCorrections RefType="CommentIn">
<RefSource>Eur Urol. 2012 May;61(5):885-6; discussion 886-7</RefSource>
<PMID Version="1">22230712</PMID>
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<DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName>
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<DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
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<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D002243">Carbolines</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000627">therapeutic use</QualifierName>
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<DescriptorName MajorTopicYN="N" UI="D003075">Coitus</DescriptorName>
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<DescriptorName MajorTopicYN="N" UI="D007172">Erectile Dysfunction</DescriptorName>
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<DescriptorName MajorTopicYN="N" UI="D011446">Prospective Studies</DescriptorName>
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<DescriptorName MajorTopicYN="N" UI="D011467">Prostate</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000187">drug effects</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000294">innervation</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D017430">Prostate-Specific Antigen</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000097">blood</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D011468">Prostatectomy</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D011471">Prostatic Neoplasms</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D011788">Quality of Life</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D011795">Surveys and Questionnaires</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D000068581">Tadalafil</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N" UI="D014549">Urinary Incontinence</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000517">prevention & control</QualifierName>
</MeshHeading>
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<Year>2011</Year>
<Month>9</Month>
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<Year>2011</Year>
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