The soft keratoprosthesis.
Identifieur interne : 002033 ( PubMed/Corpus ); précédent : 002032; suivant : 002034The soft keratoprosthesis.
Auteurs : D R CaldwellSource :
- Transactions of the American Ophthalmological Society [ 0065-9533 ] ; 1997.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Animals, Biocompatible Materials, Cats, Cercopithecus aethiops, Cornea (pathology), Cornea (surgery), Female, Guinea Pigs, Humans, Male, Materials Testing, Polytetrafluoroethylene, Postoperative Complications, Prostheses and Implants, Prosthesis Implantation, Rabbits, Urethane.
- MESH :
- chemical : Biocompatible Materials, Polytetrafluoroethylene, Urethane.
- pathology : Cornea.
- surgery : Cornea.
- Aged, Aged, 80 and over, Animals, Cats, Cercopithecus aethiops, Female, Guinea Pigs, Humans, Male, Materials Testing, Postoperative Complications, Prostheses and Implants, Prosthesis Implantation, Rabbits.
Abstract
The purpose of this work was to develop a keratoprosthesis which utilizes a biocolonizable skirt attached to a soft, elastomeric optic for world-wide application.
PubMed: 9440192
Links to Exploration step
pubmed:9440192Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The soft keratoprosthesis.</title><author><name sortKey="Caldwell, D R" sort="Caldwell, D R" uniqKey="Caldwell D" first="D R" last="Caldwell">D R Caldwell</name><affiliation><nlm:affiliation>Tulane University Medical Center, School of Medicine, Department of Ophthalmology, New Orleans, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1997">1997</date><idno type="RBID">pubmed:9440192</idno><idno type="pmid">9440192</idno><idno type="wicri:Area/PubMed/Corpus">002033</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The soft keratoprosthesis.</title><author><name sortKey="Caldwell, D R" sort="Caldwell, D R" uniqKey="Caldwell D" first="D R" last="Caldwell">D R Caldwell</name><affiliation><nlm:affiliation>Tulane University Medical Center, School of Medicine, Department of Ophthalmology, New Orleans, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Transactions of the American Ophthalmological Society</title><idno type="ISSN">0065-9533</idno><imprint><date when="1997" type="published">1997</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Animals</term><term>Biocompatible Materials</term><term>Cats</term><term>Cercopithecus aethiops</term><term>Cornea (pathology)</term><term>Cornea (surgery)</term><term>Female</term><term>Guinea Pigs</term><term>Humans</term><term>Male</term><term>Materials Testing</term><term>Polytetrafluoroethylene</term><term>Postoperative Complications</term><term>Prostheses and Implants</term><term>Prosthesis Implantation</term><term>Rabbits</term><term>Urethane</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Biocompatible Materials</term><term>Polytetrafluoroethylene</term><term>Urethane</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Cornea</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Cornea</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Animals</term><term>Cats</term><term>Cercopithecus aethiops</term><term>Female</term><term>Guinea Pigs</term><term>Humans</term><term>Male</term><term>Materials Testing</term><term>Postoperative Complications</term><term>Prostheses and Implants</term><term>Prosthesis Implantation</term><term>Rabbits</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purpose of this work was to develop a keratoprosthesis which utilizes a biocolonizable skirt attached to a soft, elastomeric optic for world-wide application.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">9440192</PMID><DateCreated><Year>1998</Year><Month>02</Month><Day>05</Day></DateCreated><DateCompleted><Year>1998</Year><Month>02</Month><Day>05</Day></DateCompleted><DateRevised><Year>2014</Year><Month>06</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0065-9533</ISSN><JournalIssue CitedMedium="Print"><Volume>95</Volume><PubDate><Year>1997</Year></PubDate></JournalIssue><Title>Transactions of the American Ophthalmological Society</Title><ISOAbbreviation>Trans Am Ophthalmol Soc</ISOAbbreviation></Journal><ArticleTitle>The soft keratoprosthesis.</ArticleTitle><Pagination><MedlinePgn>751-802</MedlinePgn></Pagination><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">The purpose of this work was to develop a keratoprosthesis which utilizes a biocolonizable skirt attached to a soft, elastomeric optic for world-wide application.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Over a period of 20 years, using in vivo animal implantation studies, a series of experiments was conducted testing materials for biocompatibility and durability which resulted in the development of an improved design. A new surgical technique was developed, using porous, biocolonizable haptics embedded within the sclera and combined with the established techniques of resection of Descemet's membrane and a conjunctival flap.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Animal implantation studies indicated that 6 haptics, equidistantly placed, was the optimal shape. Two clinical trials resulted in the selection of an aliphatic polyether-based urethane for the optic and 60 mu pore polytetrafluoroethylene for the porous ingrowth material. Heated, pressurized injection moulding proved to be the optimal bonding method between the skirt and the optic. Sclerally embedded haptics achieved excellent integration with the tissue.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This keratoprosthesis is a significant improvement over previous models with a rigid optic in that: 1. The porous ingrowth haptic is sclerally anchored, preventing extrusion. 2. It has a soft elastomeric optic which more successfully defuses the shearing forces of the keratoprosthesis/tissue interface secondary to blinking. 3. The optic is less massive and of greater circumference at the optic/tissue interface, thereby imparting less energy per area with a given movement. 4. The optic does not project posteriorly thereby decreasing anterior chamber irritation and reducing the possibility of glaucoma, uveitis, endophthalmitis, and retinal detachment. 5. This keratoprosthesis allows a normal field of view for the patient and an effective funduscopic view for the surgeon. 6. The large optical diameter eliminates problems with decentralization of the image. 7. It has a significantly better cosmetic appearance.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Caldwell</LastName><ForeName>D R</ForeName><Initials>DR</Initials><AffiliationInfo><Affiliation>Tulane University Medical Center, School of Medicine, Department of Ophthalmology, New Orleans, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>UNITED STATES</Country><MedlineTA>Trans Am Ophthalmol Soc</MedlineTA><NlmUniqueID>7506106</NlmUniqueID><ISSNLinking>0065-9533</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001672">Biocompatible Materials</NameOfSubstance></Chemical><Chemical><RegistryNumber>3IN71E75Z5</RegistryNumber><NameOfSubstance UI="D014520">Urethane</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-84-0</RegistryNumber><NameOfSubstance UI="D011138">Polytetrafluoroethylene</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Arch Ophthalmol. 1976 Feb;94(2):270-3</RefSource><PMID Version="1">1252179</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Invest Ophthalmol. 1976 Dec;15(12):986-93</RefSource><PMID Version="1">992963</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Invest Ophthalmol Vis Sci. 1977 Jan;16(1):21-31</RefSource><PMID Version="1">188776</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977 Mar-Apr;83(2):252-67</RefSource><PMID 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Version="1">4995062</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Biomed Mater Res. 1972;6(1):467-79</RefSource><PMID Version="1">5014905</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Ophthalmol. 1974 May;77(5):694-70</RefSource><PMID Version="1">4596032</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001672">Biocompatible Materials</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002415">Cats</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002522">Cercopithecus aethiops</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003315">Cornea</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000601">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006168">Guinea Pigs</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008422">Materials Testing</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D011138">Polytetrafluoroethylene</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011183">Postoperative Complications</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D019736">Prostheses and Implants</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D019919">Prosthesis Implantation</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011817">Rabbits</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D014520">Urethane</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC1298380</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1997</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1998</Year><Month>1</Month><Day>24</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1997</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">9440192</ArticleId><ArticleId IdType="pmc">PMC1298380</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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