Anterior capsule opacification: correlation of pathologic findings with clinical sequelae.
Identifieur interne : 001D32 ( PubMed/Corpus ); précédent : 001D31; suivant : 001D33Anterior capsule opacification: correlation of pathologic findings with clinical sequelae.
Auteurs : L. Werner ; S K Pandey ; D J Apple ; M. Escobar-Gomez ; L. Mclendon ; T A MackySource :
- Ophthalmology [ 0161-6420 ] ; 2001.
English descriptors
- KwdEn :
- MESH :
- chemical : Acrylic Resins, Silicone Elastomers.
- adverse effects : Lenses, Intraocular.
- etiology : Cataract.
- pathology : Anterior Eye Segment, Cataract, Lens Capsule, Crystalline, Postoperative Complications.
- Humans, Lens Implantation, Intraocular, Prosthesis Design.
Abstract
To evaluate the degree of anterior capsule opacification (ACO) in human eyes obtained postmortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs and compare the findings with clinical sequelae of capsular shrinkage.
PubMed: 11535472
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Anterior capsule opacification: correlation of pathologic findings with clinical sequelae.</title><author><name sortKey="Werner, L" sort="Werner, L" uniqKey="Werner L" first="L" last="Werner">L. Werner</name><affiliation><nlm:affiliation>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pandey, S K" sort="Pandey, S K" uniqKey="Pandey S" first="S K" last="Pandey">S K Pandey</name></author><author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D J" last="Apple">D J Apple</name></author><author><name sortKey="Escobar Gomez, M" sort="Escobar Gomez, M" uniqKey="Escobar Gomez M" first="M" last="Escobar-Gomez">M. Escobar-Gomez</name></author><author><name sortKey="Mclendon, L" sort="Mclendon, L" uniqKey="Mclendon L" first="L" last="Mclendon">L. Mclendon</name></author><author><name sortKey="Macky, T A" sort="Macky, T A" uniqKey="Macky T" first="T A" last="Macky">T A Macky</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2001">2001</date><idno type="RBID">pubmed:11535472</idno><idno type="pmid">11535472</idno><idno type="wicri:Area/PubMed/Corpus">001D32</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Anterior capsule opacification: correlation of pathologic findings with clinical sequelae.</title><author><name sortKey="Werner, L" sort="Werner, L" uniqKey="Werner L" first="L" last="Werner">L. Werner</name><affiliation><nlm:affiliation>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pandey, S K" sort="Pandey, S K" uniqKey="Pandey S" first="S K" last="Pandey">S K Pandey</name></author><author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D J" last="Apple">D J Apple</name></author><author><name sortKey="Escobar Gomez, M" sort="Escobar Gomez, M" uniqKey="Escobar Gomez M" first="M" last="Escobar-Gomez">M. Escobar-Gomez</name></author><author><name sortKey="Mclendon, L" sort="Mclendon, L" uniqKey="Mclendon L" first="L" last="Mclendon">L. Mclendon</name></author><author><name sortKey="Macky, T A" sort="Macky, T A" uniqKey="Macky T" first="T A" last="Macky">T A Macky</name></author></analytic><series><title level="j">Ophthalmology</title><idno type="ISSN">0161-6420</idno><imprint><date when="2001" type="published">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term><term>Anterior Eye Segment (pathology)</term><term>Cataract (etiology)</term><term>Cataract (pathology)</term><term>Humans</term><term>Lens Capsule, Crystalline (pathology)</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular (adverse effects)</term><term>Postoperative Complications (pathology)</term><term>Prosthesis Design</term><term>Silicone Elastomers</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term><term>Silicone Elastomers</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lenses, Intraocular</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cataract</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Anterior Eye Segment</term><term>Cataract</term><term>Lens Capsule, Crystalline</term><term>Postoperative Complications</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Lens Implantation, Intraocular</term><term>Prosthesis Design</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To evaluate the degree of anterior capsule opacification (ACO) in human eyes obtained postmortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs and compare the findings with clinical sequelae of capsular shrinkage.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">11535472</PMID><DateCreated><Year>2001</Year><Month>09</Month><Day>05</Day></DateCreated><DateCompleted><Year>2001</Year><Month>09</Month><Day>20</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0161-6420</ISSN><JournalIssue CitedMedium="Print"><Volume>108</Volume><Issue>9</Issue><PubDate><Year>2001</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Ophthalmology</Title><ISOAbbreviation>Ophthalmology</ISOAbbreviation></Journal><ArticleTitle>Anterior capsule opacification: correlation of pathologic findings with clinical sequelae.</ArticleTitle><Pagination><MedlinePgn>1675-81</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate the degree of anterior capsule opacification (ACO) in human eyes obtained postmortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs and compare the findings with clinical sequelae of capsular shrinkage.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">Comparative autopsy tissue study with clinicopathologic correlations.</AbstractText><AbstractText Label="MATERIALS" NlmCategory="METHODS">Three hundred formalin-fixed human eyes containing the following PC-IOL styles were analyzed: (1) one-piece polymethyl methacrylate (PMMA) optic-PMMA haptic (n = 50), one-piece silicone-plate IOL, with large (2) or small (3) fixation holes (n = 35), (4) three-piece PMMA optic-Prolene haptic (n = 50), (5) three-piece acrylic optic-PMMA haptic (n = 55), three-piece silicone optic with PMMA (6) or polyimide (7) haptics (n = 30), and (8) three-piece silicone optic-Prolene haptic (n = 80) lenses.</AbstractText><AbstractText Label="TESTING" NlmCategory="METHODS">The eyes were sectioned in the equatorial plane for gross examination of the capsular bag from a posterior view. The cornea and iris were then excised for evaluation from an anterior view.</AbstractText><AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">ACO was scored in each eye from 0 to IV, according to the degree/area of capsule opacification. Capsulorrhexis size and IOL decentration were measured with calipers.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The overall differences among the IOL groups regarding the three parameters were significant (ACO score: P < 0.001; capsulorrhexis diameter: P = 0.036; IOL decentration: P = 0.012). Mean ACO scores were highest with the large- and small-hole one-piece silicone-plate lenses (2.543 +/- 0.950) and lowest with the three-piece acrylic optic-PMMA haptic lenses (0.600 +/- 0.710). Of 10 cases of capsulorrhexis phimosis observed in the study, 7 cases were associated with three-piece silicone optic-Prolene haptic lenses, which also presented the highest mean decentration (0.375 +/- 0.601 mm).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our results confirm previous histopathologic observations that the rate of ACO is the lowest with acrylic lenses and higher with plate-haptic silicone IOLs. Nevertheless, clinical sequelae of capsular shrinkage are also very important with three-piece silicone optic-Prolene haptic designs. Thus, IOL material and design are significant factors in the development of ACO, but they ultimately also influence the clinical presentation of capsular shrinkage.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Werner</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pandey</LastName><ForeName>S K</ForeName><Initials>SK</Initials></Author><Author ValidYN="Y"><LastName>Apple</LastName><ForeName>D J</ForeName><Initials>DJ</Initials></Author><Author ValidYN="Y"><LastName>Escobar-Gomez</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>McLendon</LastName><ForeName>L</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Macky</LastName><ForeName>T A</ForeName><Initials>TA</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Ophthalmology</MedlineTA><NlmUniqueID>7802443</NlmUniqueID><ISSNLinking>0161-6420</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000180">Acrylic Resins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012826">Silicone Elastomers</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000180">Acrylic Resins</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000869">Anterior Eye Segment</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002386">Cataract</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007903">Lens Capsule, Crystalline</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D019654">Lens Implantation, Intraocular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007910">Lenses, Intraocular</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011183">Postoperative Complications</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012826">Silicone Elastomers</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>9</Month><Day>6</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>9</Month><Day>21</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>9</Month><Day>6</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11535472</ArticleId><ArticleId IdType="pii">S0161-6420(01)00674-1</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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