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Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.

Identifieur interne : 001A38 ( PubMed/Corpus ); précédent : 001A37; suivant : 001A39

Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.

Auteurs : Liliana Werner ; Nick Mamalis ; Suresh K. Pandey ; Andrea M. Izak ; Christian D. Nilson ; Brandon L. Davis ; Christopher Weight ; David J. Apple

Source :

Journal of cataract and refractive surgery [ 0886-3350 ] ; 2004.

RBID : pubmed:15519096

English descriptors

KwdEn :
- Acrylic Resins, Animals, Biocompatible Materials, Cataract (etiology), Cataract (prevention & control), Lens Capsule, Crystalline (pathology), Lens Implantation, Intraocular (adverse effects), Lenses, Intraocular (adverse effects), Postoperative Complications, Prosthesis Design, Rabbits.
MESH :
- chemical : Acrylic Resins, Biocompatible Materials.
- adverse effects : Lens Implantation, Intraocular, Lenses, Intraocular.
- etiology : Cataract.
- pathology : Lens Capsule, Crystalline.
- prevention & control : Cataract.
- Animals, Postoperative Complications, Prosthesis Design, Rabbits.

Abstract

To evaluate the development of posterior capsule opacification (PCO) after implantation of single-piece hydrophilic acrylic intraocular lenses (IOLs) with an enhanced square edge.

DOI: 10.1016/j.jcrs.2004.02.085
PubMed: 15519096

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pubmed:15519096

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.</title>
<author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
<affiliation><nlm:affiliation>David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA. liliana.werner@hsc.utah.edu</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mamalis, Nick" sort="Mamalis, Nick" uniqKey="Mamalis N" first="Nick" last="Mamalis">Nick Mamalis</name>
</author>
<author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K" last="Pandey">Suresh K. Pandey</name>
</author>
<author><name sortKey="Izak, Andrea M" sort="Izak, Andrea M" uniqKey="Izak A" first="Andrea M" last="Izak">Andrea M. Izak</name>
</author>
<author><name sortKey="Nilson, Christian D" sort="Nilson, Christian D" uniqKey="Nilson C" first="Christian D" last="Nilson">Christian D. Nilson</name>
</author>
<author><name sortKey="Davis, Brandon L" sort="Davis, Brandon L" uniqKey="Davis B" first="Brandon L" last="Davis">Brandon L. Davis</name>
</author>
<author><name sortKey="Weight, Christopher" sort="Weight, Christopher" uniqKey="Weight C" first="Christopher" last="Weight">Christopher Weight</name>
</author>
<author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J" last="Apple">David J. Apple</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2004">2004</date>
<idno type="doi">10.1016/j.jcrs.2004.02.085</idno>
<idno type="RBID">pubmed:15519096</idno>
<idno type="pmid">15519096</idno>
<idno type="wicri:Area/PubMed/Corpus">001A38</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.</title>
<author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
<affiliation><nlm:affiliation>David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA. liliana.werner@hsc.utah.edu</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Mamalis, Nick" sort="Mamalis, Nick" uniqKey="Mamalis N" first="Nick" last="Mamalis">Nick Mamalis</name>
</author>
<author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K" last="Pandey">Suresh K. Pandey</name>
</author>
<author><name sortKey="Izak, Andrea M" sort="Izak, Andrea M" uniqKey="Izak A" first="Andrea M" last="Izak">Andrea M. Izak</name>
</author>
<author><name sortKey="Nilson, Christian D" sort="Nilson, Christian D" uniqKey="Nilson C" first="Christian D" last="Nilson">Christian D. Nilson</name>
</author>
<author><name sortKey="Davis, Brandon L" sort="Davis, Brandon L" uniqKey="Davis B" first="Brandon L" last="Davis">Brandon L. Davis</name>
</author>
<author><name sortKey="Weight, Christopher" sort="Weight, Christopher" uniqKey="Weight C" first="Christopher" last="Weight">Christopher Weight</name>
</author>
<author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J" last="Apple">David J. Apple</name>
</author>
</analytic>
<series><title level="j">Journal of cataract and refractive surgery</title>
<idno type="ISSN">0886-3350</idno>
<imprint><date when="2004" type="published">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term>
<term>Animals</term>
<term>Biocompatible Materials</term>
<term>Cataract (etiology)</term>
<term>Cataract (prevention & control)</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Implantation, Intraocular (adverse effects)</term>
<term>Lenses, Intraocular (adverse effects)</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
<term>Rabbits</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term>
<term>Biocompatible Materials</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cataract</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cataract</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
<term>Rabbits</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">To evaluate the development of posterior capsule opacification (PCO) after implantation of single-piece hydrophilic acrylic intraocular lenses (IOLs) with an enhanced square edge.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">15519096</PMID>
<DateCreated><Year>2004</Year>
<Month>11</Month>
<Day>02</Day>
</DateCreated>
<DateCompleted><Year>2005</Year>
<Month>01</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised><Year>2006</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0886-3350</ISSN>
<JournalIssue CitedMedium="Print"><Volume>30</Volume>
<Issue>11</Issue>
<PubDate><Year>2004</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>Journal of cataract and refractive surgery</Title>
<ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation>
</Journal>
<ArticleTitle>Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.</ArticleTitle>
<Pagination><MedlinePgn>2403-9</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To evaluate the development of posterior capsule opacification (PCO) after implantation of single-piece hydrophilic acrylic intraocular lenses (IOLs) with an enhanced square edge.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The standard 570H Centerflex (Rayner Ltd.) design was compared to 2 new designs with enhanced square edges: the 570E and the 570C. Ten IOLs of each type were implanted in a randomized manner by the same surgeon in 15 pigmented rabbits. After a follow-up of 3 weeks, the rabbits were killed and the eyes were analyzed from the posterior view. The intensity of central PCO, peripheral PCO, and Soemmering's ring formation was graded from 0 to 4. The area of Soemmering's ring was graded from 0 to 4 based on the number of quadrants involved. Other parameters analyzed were capsulorhexis coverage of the IOL edge and IOL centration and fixation. Results from the posterior view were complemented by histopathological evaluation.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Posterior capsule opacification was lowest in the 570C group, highest in the 570H group, and intermediate in the 570E group. There was a statistically significant difference between the 3 groups in peripheral PCO (P = .039). No significant difference was found between the groups in the other parameters analyzed. When cell ingrowth occurred with the 570H, it started at the optic-haptic junctions, as observed during the clinical follow-up and confirmed by gross and histopathological analyses.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The square optic edge is the most important IOL design feature for PCO prevention. However, it should be present for 360 degrees around the IOL optic to provide an effective barrier effect.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Werner</LastName>
<ForeName>Liliana</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>David J. Apple, MD Laboratories for Ophthalmic Devices Research, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA. liliana.werner@hsc.utah.edu</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mamalis</LastName>
<ForeName>Nick</ForeName>
<Initials>N</Initials>
</Author>
<Author ValidYN="Y"><LastName>Pandey</LastName>
<ForeName>Suresh K</ForeName>
<Initials>SK</Initials>
</Author>
<Author ValidYN="Y"><LastName>Izak</LastName>
<ForeName>Andrea M</ForeName>
<Initials>AM</Initials>
</Author>
<Author ValidYN="Y"><LastName>Nilson</LastName>
<ForeName>Christian D</ForeName>
<Initials>CD</Initials>
</Author>
<Author ValidYN="Y"><LastName>Davis</LastName>
<ForeName>Brandon L</ForeName>
<Initials>BL</Initials>
</Author>
<Author ValidYN="Y"><LastName>Weight</LastName>
<ForeName>Christopher</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Apple</LastName>
<ForeName>David J</ForeName>
<Initials>DJ</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Cataract Refract Surg</MedlineTA>
<NlmUniqueID>8604171</NlmUniqueID>
<ISSNLinking>0886-3350</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000180">Acrylic Resins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D001672">Biocompatible Materials</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D000180">Acrylic Resins</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D001672">Biocompatible Materials</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002386">Cataract</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000209">etiology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000517">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007903">Lens Capsule, Crystalline</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019654">Lens Implantation, Intraocular</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000009">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007910">Lenses, Intraocular</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000009">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D011183">Postoperative Complications</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011817">Rabbits</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="accepted"><Year>2004</Year>
<Month>Feb</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2004</Year>
<Month>11</Month>
<Day>3</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2005</Year>
<Month>1</Month>
<Day>26</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2004</Year>
<Month>11</Month>
<Day>3</Day>
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<Minute>0</Minute>
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</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pii">S0886335004004080</ArticleId>
<ArticleId IdType="doi">10.1016/j.jcrs.2004.02.085</ArticleId>
<ArticleId IdType="pubmed">15519096</ArticleId>
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Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.

Posterior capsule opacification in rabbit eyes implanted with hydrophilic acrylic intraocular lenses with enhanced square edge.

Source :

English descriptors

Abstract

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