Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification: five-year results of a randomized study.
Identifieur interne : 001947 ( PubMed/Corpus ); précédent : 001946; suivant : 001948Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification: five-year results of a randomized study.
Auteurs : Stefan Sacu ; Rupert Menapace ; Oliver Findl ; Barbara Kiss ; Wolf Buehl ; Michael GeorgopoulosSource :
- American journal of ophthalmology [ 0002-9394 ] ; 2005.
English descriptors
- KwdEn :
- Aged, Capsulorhexis, Cataract (etiology), Cell Movement, Double-Blind Method, Epithelial Cells (pathology), Fibrosis, Follow-Up Studies, Humans, Lens Capsule, Crystalline (pathology), Lens Implantation, Intraocular, Lenses, Intraocular, Phacoemulsification, Postoperative Complications, Prosthesis Design, Silicone Elastomers, Treatment Outcome, Visual Acuity.
- MESH :
- chemical : Silicone Elastomers.
- etiology : Cataract.
- pathology : Epithelial Cells, Lens Capsule, Crystalline.
- Aged, Capsulorhexis, Cell Movement, Double-Blind Method, Fibrosis, Follow-Up Studies, Humans, Lens Implantation, Intraocular, Lenses, Intraocular, Phacoemulsification, Postoperative Complications, Prosthesis Design, Treatment Outcome, Visual Acuity.
Abstract
To compare the intensity of capsule opacification with the sharp and the round optic edge variant of an open-loop hydrophobic silicone intraocular lens (IOL).
DOI: 10.1016/j.ajo.2004.12.050
PubMed: 15808167
Links to Exploration step
pubmed:15808167Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification: five-year results of a randomized study.</title>
<author><name sortKey="Sacu, Stefan" sort="Sacu, Stefan" uniqKey="Sacu S" first="Stefan" last="Sacu">Stefan Sacu</name>
<affiliation><nlm:affiliation>Medical University of Vienna, Department of Ophthalmology, Vienna, Austria.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name>
</author>
<author><name sortKey="Findl, Oliver" sort="Findl, Oliver" uniqKey="Findl O" first="Oliver" last="Findl">Oliver Findl</name>
</author>
<author><name sortKey="Kiss, Barbara" sort="Kiss, Barbara" uniqKey="Kiss B" first="Barbara" last="Kiss">Barbara Kiss</name>
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<author><name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name>
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<author><name sortKey="Georgopoulos, Michael" sort="Georgopoulos, Michael" uniqKey="Georgopoulos M" first="Michael" last="Georgopoulos">Michael Georgopoulos</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification: five-year results of a randomized study.</title>
<author><name sortKey="Sacu, Stefan" sort="Sacu, Stefan" uniqKey="Sacu S" first="Stefan" last="Sacu">Stefan Sacu</name>
<affiliation><nlm:affiliation>Medical University of Vienna, Department of Ophthalmology, Vienna, Austria.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name>
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<author><name sortKey="Findl, Oliver" sort="Findl, Oliver" uniqKey="Findl O" first="Oliver" last="Findl">Oliver Findl</name>
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<author><name sortKey="Kiss, Barbara" sort="Kiss, Barbara" uniqKey="Kiss B" first="Barbara" last="Kiss">Barbara Kiss</name>
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<author><name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name>
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<author><name sortKey="Georgopoulos, Michael" sort="Georgopoulos, Michael" uniqKey="Georgopoulos M" first="Michael" last="Georgopoulos">Michael Georgopoulos</name>
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<series><title level="j">American journal of ophthalmology</title>
<idno type="ISSN">0002-9394</idno>
<imprint><date when="2005" type="published">2005</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Capsulorhexis</term>
<term>Cataract (etiology)</term>
<term>Cell Movement</term>
<term>Double-Blind Method</term>
<term>Epithelial Cells (pathology)</term>
<term>Fibrosis</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Phacoemulsification</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
<term>Silicone Elastomers</term>
<term>Treatment Outcome</term>
<term>Visual Acuity</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Silicone Elastomers</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cataract</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Epithelial Cells</term>
<term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Capsulorhexis</term>
<term>Cell Movement</term>
<term>Double-Blind Method</term>
<term>Fibrosis</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Phacoemulsification</term>
<term>Postoperative Complications</term>
<term>Prosthesis Design</term>
<term>Treatment Outcome</term>
<term>Visual Acuity</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">To compare the intensity of capsule opacification with the sharp and the round optic edge variant of an open-loop hydrophobic silicone intraocular lens (IOL).</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">15808167</PMID>
<DateCreated><Year>2005</Year>
<Month>04</Month>
<Day>05</Day>
</DateCreated>
<DateCompleted><Year>2005</Year>
<Month>04</Month>
<Day>25</Day>
</DateCompleted>
<DateRevised><Year>2006</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0002-9394</ISSN>
<JournalIssue CitedMedium="Print"><Volume>139</Volume>
<Issue>4</Issue>
<PubDate><Year>2005</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>American journal of ophthalmology</Title>
<ISOAbbreviation>Am. J. Ophthalmol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification: five-year results of a randomized study.</ArticleTitle>
<Pagination><MedlinePgn>696-703</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To compare the intensity of capsule opacification with the sharp and the round optic edge variant of an open-loop hydrophobic silicone intraocular lens (IOL).</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Randomized, controlled, double-blind clinical trial with intraindividual comparison.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Fifty-one patients with bilateral age-related cataract were included (102 eyes). Each patient had had cataract surgery in both eyes and received a Microsil IOL with a sharp optic edge design (model S) in one eye and a Microsil IOL with a round optic edge design (model R) in the fellow eye. Both IOLs had an identical haptic design (nonangulated polymethylmethacrylate) and silicone optic material. The patients were examined at the slit lamp, best-corrected visual acuity was assessed, and standardized high-resolution digital retroillumination images of the posterior capsule were taken 5 years after surgery. The intensity of regeneratory posterior capsule opacification (rPCO), fibrotic PCO (fPCO), and anterior capsule opacification (ACO) was assessed subjectively at the slit lamp, and of rPCO, objectively using automated image analysis software (AQUA). The need for an Nd:YAG laser capsulotomy (Nd:YAG-LCT) was noted.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The mean AQUA PCO score was 1.2 for the model S and 2.4 for the model R lens (P = .001). The model S lens also led to less peripheral fPCO (P = .003). Concerning ACO, there was no significant difference between both IOL groups (P = .72). Whereas no capsulotomy was required with the model S, four cases (16%) had been performed in the model R group.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Five years postoperatively, the sharp-edged silicone IOL showed less rPCO and fPCO than the round-edged IOL. However, regarding ACO, there was no significant difference between both IOL styles.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sacu</LastName>
<ForeName>Stefan</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Medical University of Vienna, Department of Ophthalmology, Vienna, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Menapace</LastName>
<ForeName>Rupert</ForeName>
<Initials>R</Initials>
</Author>
<Author ValidYN="Y"><LastName>Findl</LastName>
<ForeName>Oliver</ForeName>
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<Author ValidYN="Y"><LastName>Kiss</LastName>
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<Author ValidYN="Y"><LastName>Buehl</LastName>
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<Author ValidYN="Y"><LastName>Georgopoulos</LastName>
<ForeName>Michael</ForeName>
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</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType>
<PublicationType UI="D003160">Comparative Study</PublicationType>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Am J Ophthalmol</MedlineTA>
<NlmUniqueID>0370500</NlmUniqueID>
<ISSNLinking>0002-9394</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012826">Silicone Elastomers</NameOfSubstance>
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<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019923">Capsulorhexis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002386">Cataract</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000209">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002465">Cell Movement</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004311">Double-Blind Method</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004847">Epithelial Cells</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005355">Fibrosis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005500">Follow-Up Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007903">Lens Capsule, Crystalline</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019654">Lens Implantation, Intraocular</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D007910">Lenses, Intraocular</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D018918">Phacoemulsification</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D011183">Postoperative Complications</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D012826">Silicone Elastomers</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D016896">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014792">Visual Acuity</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
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