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Incidence and risk factors of Nd:YAG capsulotomy after phacoemulsification in non-diabetic and diabetic patients.

Identifieur interne : 001769 ( PubMed/Corpus ); précédent : 001768; suivant : 001770

Incidence and risk factors of Nd:YAG capsulotomy after phacoemulsification in non-diabetic and diabetic patients.

Auteurs : Mostafa A. Elgohary ; Jonathan G. Dowler

Source :

RBID : pubmed:16925699

English descriptors

Abstract

To estimate the cumulative incidence and identify the risk factors of posterior capsule opacification (PCO) that required Nd:YAG capsulotomy in non-diabetic and diabetic patients.

DOI: 10.1111/j.1442-9071.2006.01263.x
PubMed: 16925699

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pubmed:16925699

Le document en format XML

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<title xml:lang="en">Incidence and risk factors of Nd:YAG capsulotomy after phacoemulsification in non-diabetic and diabetic patients.</title>
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<name sortKey="Elgohary, Mostafa A" sort="Elgohary, Mostafa A" uniqKey="Elgohary M" first="Mostafa A" last="Elgohary">Mostafa A. Elgohary</name>
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<nlm:affiliation>Medical Retina Service, Moorfields Eye Hospital, London, UK, and Tanta Ophthalmology University Hospital, Egypt. m.elgohary@doctors.org.uk</nlm:affiliation>
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<name sortKey="Dowler, Jonathan G" sort="Dowler, Jonathan G" uniqKey="Dowler J" first="Jonathan G" last="Dowler">Jonathan G. Dowler</name>
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<title xml:lang="en">Incidence and risk factors of Nd:YAG capsulotomy after phacoemulsification in non-diabetic and diabetic patients.</title>
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<name sortKey="Elgohary, Mostafa A" sort="Elgohary, Mostafa A" uniqKey="Elgohary M" first="Mostafa A" last="Elgohary">Mostafa A. Elgohary</name>
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<name sortKey="Dowler, Jonathan G" sort="Dowler, Jonathan G" uniqKey="Dowler J" first="Jonathan G" last="Dowler">Jonathan G. Dowler</name>
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<title level="j">Clinical & experimental ophthalmology</title>
<idno type="ISSN">1442-6404</idno>
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<date when="2006" type="published">2006</date>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cataract (epidemiology)</term>
<term>Cataract (etiology)</term>
<term>Diabetes Complications</term>
<term>Female</term>
<term>Humans</term>
<term>Incidence</term>
<term>Laser Therapy (statistics & numerical data)</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Capsule, Crystalline (surgery)</term>
<term>Lens Implantation, Intraocular</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Phacoemulsification</term>
<term>Postoperative Complications (epidemiology)</term>
<term>Postoperative Complications (etiology)</term>
<term>Proportional Hazards Models</term>
<term>Retrospective Studies</term>
<term>Risk Factors</term>
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<term>Cataract</term>
<term>Postoperative Complications</term>
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<term>Cataract</term>
<term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en">
<term>Laser Therapy</term>
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<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Lens Capsule, Crystalline</term>
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<term>Adult</term>
<term>Aged</term>
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<term>Diabetes Complications</term>
<term>Female</term>
<term>Humans</term>
<term>Incidence</term>
<term>Lens Implantation, Intraocular</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Phacoemulsification</term>
<term>Proportional Hazards Models</term>
<term>Retrospective Studies</term>
<term>Risk Factors</term>
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<front>
<div type="abstract" xml:lang="en">To estimate the cumulative incidence and identify the risk factors of posterior capsule opacification (PCO) that required Nd:YAG capsulotomy in non-diabetic and diabetic patients.</div>
</front>
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<PMID Version="1">16925699</PMID>
<DateCreated>
<Year>2006</Year>
<Month>08</Month>
<Day>23</Day>
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<DateCompleted>
<Year>2006</Year>
<Month>10</Month>
<Day>03</Day>
</DateCompleted>
<DateRevised>
<Year>2007</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
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<ISSN IssnType="Print">1442-6404</ISSN>
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<Volume>34</Volume>
<Issue>6</Issue>
<PubDate>
<Year>2006</Year>
<Month>Aug</Month>
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<Title>Clinical & experimental ophthalmology</Title>
<ISOAbbreviation>Clin. Experiment. Ophthalmol.</ISOAbbreviation>
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<ArticleTitle>Incidence and risk factors of Nd:YAG capsulotomy after phacoemulsification in non-diabetic and diabetic patients.</ArticleTitle>
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<MedlinePgn>526-34</MedlinePgn>
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<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To estimate the cumulative incidence and identify the risk factors of posterior capsule opacification (PCO) that required Nd:YAG capsulotomy in non-diabetic and diabetic patients.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Retrospective case-note review of 806 consecutive patients that underwent phacoemulsification and intraocular lens (IOL) implantation, 327 (40.6%) of whom were diabetic.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The cumulative incidence of Nd:YAG capsulotomy were 10.6%, 14.8%, 21.2% and 28.6% in non-diabetic patients; and 9%, 9.4%, 15.3% and 5.3% in diabetic patients after 1, 2, 3 and 4 years, respectively. A multivariate Cox regression analysis showed that, over the follow-up period, diabetes mellitus was associated with a decreased risk of Nd:YAG capsulotomy (hazard ratio [HR]=0.69; 95% confidence interval [CI] 0.47-0.99; P=0.047), whereas age of 65 years or younger (HR=1.58; 95% CI 1.09-2.27; P=0.02), polymethylmethacrylate (PMMA) (HR=3.98; 95% CI 1.60-9.95; P=0.003) or plate-haptic silicone IOLs (HR=3.75; 95% CI 1.60-8.80; P=0.002) in comparison with three-piece silicone IOLs, postoperative inflammation (HR=2.62; 95% CI 1.56-4.42; P<0.001) and pars plana vitrectomy (HR=1.85; 95% CI 1.20-2.83; P=0.005) were associated with an increased risk. Subgroup analysis showed that in non-diabetic patients, male gender (HR=1.63; 95% CI 1.04-2.57; P=0.03) was an additional risk factor and in diabetic patients there was no significant association between diabetes type, duration or retinopathy grade and the risk of Nd:YAG capsulotomy.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Although diabetes mellitus appears to be associated with a lower long-term incidence and a decreased risk of Nd:YAG capsulotomy, younger age, pars plana vitrectomy, postoperative inflammation, plate-haptic silicone and PMMA IOLs in addition to male gender in non-diabetic patients appear to be associated with a greater risk. Estimation of the incidence and risk factors of PCO should help in patient counselling and to design methods to reduce or prevent its development.</AbstractText>
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<Affiliation>Medical Retina Service, Moorfields Eye Hospital, London, UK, and Tanta Ophthalmology University Hospital, Egypt. m.elgohary@doctors.org.uk</Affiliation>
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