Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
Identifieur interne : 001579 ( PubMed/Corpus ); précédent : 001578; suivant : 001580Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
Auteurs : Matthias G. Wirtitsch ; Rupert Menapace ; Michael Georgopoulos ; Georg Rainer ; Wolf Buehl ; Harald HeinzlSource :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 2007.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Antihypertensive Agents (administration & dosage), Antihypertensive Agents (adverse effects), Capsulorhexis (methods), Cataract (complications), Combined Modality Therapy, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Intraocular Pressure, Lens Implantation, Intraocular, Lenses, Intraocular, Male, Middle Aged, Ocular Hypertension (prevention & control), Postoperative Complications, Prospective Studies, Prosthesis Design, Sulfonamides (administration & dosage), Sulfonamides (adverse effects), Thiophenes (administration & dosage), Thiophenes (adverse effects), Timolol (administration & dosage), Timolol (adverse effects).
- MESH :
- chemical , administration & dosage : Antihypertensive Agents, Sulfonamides, Thiophenes, Timolol.
- chemical , adverse effects : Antihypertensive Agents, Sulfonamides, Thiophenes, Timolol.
- complications : Cataract.
- methods : Capsulorhexis.
- prevention & control : Ocular Hypertension.
- Aged, Aged, 80 and over, Combined Modality Therapy, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Intraocular Pressure, Lens Implantation, Intraocular, Lenses, Intraocular, Male, Middle Aged, Postoperative Complications, Prospective Studies, Prosthesis Design.
Abstract
To assess the safety, in terms of the intraocular pressure (IOP), of cataract surgery with primary posterior continuous curvilinear capsulorhexis (PPCCC) and a postoperative dose of a fixed dorzolamide-timolol combination and evaluate the effect of intraocular lens (IOL) haptic angulation.
DOI: 10.1016/j.jcrs.2007.05.039
PubMed: 17889772
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pubmed:17889772Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.</title><author><name sortKey="Wirtitsch, Matthias G" sort="Wirtitsch, Matthias G" uniqKey="Wirtitsch M" first="Matthias G" last="Wirtitsch">Matthias G. Wirtitsch</name><affiliation><nlm:affiliation>Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name></author><author><name sortKey="Georgopoulos, Michael" sort="Georgopoulos, Michael" uniqKey="Georgopoulos M" first="Michael" last="Georgopoulos">Michael Georgopoulos</name></author><author><name sortKey="Rainer, Georg" sort="Rainer, Georg" uniqKey="Rainer G" first="Georg" last="Rainer">Georg Rainer</name></author><author><name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name></author><author><name sortKey="Heinzl, Harald" sort="Heinzl, Harald" uniqKey="Heinzl H" first="Harald" last="Heinzl">Harald Heinzl</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1016/j.jcrs.2007.05.039</idno><idno type="RBID">pubmed:17889772</idno><idno type="pmid">17889772</idno><idno type="wicri:Area/PubMed/Corpus">001579</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.</title><author><name sortKey="Wirtitsch, Matthias G" sort="Wirtitsch, Matthias G" uniqKey="Wirtitsch M" first="Matthias G" last="Wirtitsch">Matthias G. Wirtitsch</name><affiliation><nlm:affiliation>Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.</nlm:affiliation></affiliation></author><author><name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name></author><author><name sortKey="Georgopoulos, Michael" sort="Georgopoulos, Michael" uniqKey="Georgopoulos M" first="Michael" last="Georgopoulos">Michael Georgopoulos</name></author><author><name sortKey="Rainer, Georg" sort="Rainer, Georg" uniqKey="Rainer G" first="Georg" last="Rainer">Georg Rainer</name></author><author><name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name></author><author><name sortKey="Heinzl, Harald" sort="Heinzl, Harald" uniqKey="Heinzl H" first="Harald" last="Heinzl">Harald Heinzl</name></author></analytic><series><title level="j">Journal of cataract and refractive surgery</title><idno type="ISSN">0886-3350</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Antihypertensive Agents (administration & dosage)</term><term>Antihypertensive Agents (adverse effects)</term><term>Capsulorhexis (methods)</term><term>Cataract (complications)</term><term>Combined Modality Therapy</term><term>Double-Blind Method</term><term>Drug Therapy, Combination</term><term>Female</term><term>Humans</term><term>Intraocular Pressure</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Male</term><term>Middle Aged</term><term>Ocular Hypertension (prevention & control)</term><term>Postoperative Complications</term><term>Prospective Studies</term><term>Prosthesis Design</term><term>Sulfonamides (administration & dosage)</term><term>Sulfonamides (adverse effects)</term><term>Thiophenes (administration & dosage)</term><term>Thiophenes (adverse effects)</term><term>Timolol (administration & dosage)</term><term>Timolol (adverse effects)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antihypertensive Agents</term><term>Sulfonamides</term><term>Thiophenes</term><term>Timolol</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antihypertensive Agents</term><term>Sulfonamides</term><term>Thiophenes</term><term>Timolol</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Cataract</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Capsulorhexis</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Ocular Hypertension</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Combined Modality Therapy</term><term>Double-Blind Method</term><term>Drug Therapy, Combination</term><term>Female</term><term>Humans</term><term>Intraocular Pressure</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Male</term><term>Middle Aged</term><term>Postoperative Complications</term><term>Prospective Studies</term><term>Prosthesis Design</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To assess the safety, in terms of the intraocular pressure (IOP), of cataract surgery with primary posterior continuous curvilinear capsulorhexis (PPCCC) and a postoperative dose of a fixed dorzolamide-timolol combination and evaluate the effect of intraocular lens (IOL) haptic angulation.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">17889772</PMID><DateCreated><Year>2007</Year><Month>09</Month><Day>24</Day></DateCreated><DateCompleted><Year>2007</Year><Month>12</Month><Day>13</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0886-3350</ISSN><JournalIssue CitedMedium="Print"><Volume>33</Volume><Issue>10</Issue><PubDate><Year>2007</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Journal of cataract and refractive surgery</Title><ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation></Journal><ArticleTitle>Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.</ArticleTitle><Pagination><MedlinePgn>1754-9</MedlinePgn></Pagination><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To assess the safety, in terms of the intraocular pressure (IOP), of cataract surgery with primary posterior continuous curvilinear capsulorhexis (PPCCC) and a postoperative dose of a fixed dorzolamide-timolol combination and evaluate the effect of intraocular lens (IOL) haptic angulation.</AbstractText><AbstractText Label="SETTING" NlmCategory="METHODS">Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">In this prospective randomized double-masked bilateral study, 88 eyes of 44 consecutive patients with age-related cataract were included in an intraindividual comparison study. All patients had standardized cataract surgery with PPCCC and IOL implantation in the capsular bag followed by a postoperative dose of a fixed dorzolamide-timolol combination. Patients were randomly assigned to receive an ACR6D SE IOL (Laboratoires Cornéal) in 1 eye and a Centerflex (C-flex) 570C IOL (Rayner Surgical GmbH) in the contralateral eye. The IOP was measured at baseline and postoperatively at 6 and 24 hours as well as 1 week.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Intraindividual comparison showed statistically significantly higher IOP measurements in the C-flex 570C nonangulated IOL group than in the ACR6D SE angulated IOL group at 24 hours (P = .003) and 1 week (P = .043). The highest IOP spikes (34 mm Hg) were at 6 hours in 2 eyes with a C-flex 570C IOL. The ACR6D SE group had statistically significant changes in IOP between preoperative and all postoperative time points. In the C-flex 570C group, the only statistically significant change in IOP was between preoperatively and 6 hours postoperatively.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Cataract surgery with PPCCC was safe in terms of the postoperative IOP course. Haptic angulation slightly decreased the overall IOP rise and the incidence of IOP rises above 30 mm Hg.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wirtitsch</LastName><ForeName>Matthias G</ForeName><Initials>MG</Initials><AffiliationInfo><Affiliation>Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Menapace</LastName><ForeName>Rupert</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Georgopoulos</LastName><ForeName>Michael</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Rainer</LastName><ForeName>Georg</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Buehl</LastName><ForeName>Wolf</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>Heinzl</LastName><ForeName>Harald</ForeName><Initials>H</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Cataract Refract Surg</MedlineTA><NlmUniqueID>8604171</NlmUniqueID><ISSNLinking>0886-3350</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000959">Antihypertensive Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013449">Sulfonamides</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013876">Thiophenes</NameOfSubstance></Chemical><Chemical><RegistryNumber>817W3C6175</RegistryNumber><NameOfSubstance UI="D013999">Timolol</NameOfSubstance></Chemical><Chemical><RegistryNumber>9JDX055TW1</RegistryNumber><NameOfSubstance UI="C062765">dorzolamide</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000959">Antihypertensive Agents</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000008">administration & dosage</QualifierName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D019923">Capsulorhexis</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002386">Cataract</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003131">Combined Modality Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004311">Double-Blind Method</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004359">Drug Therapy, Combination</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D007429">Intraocular Pressure</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D019654">Lens Implantation, Intraocular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D007910">Lenses, Intraocular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009798">Ocular Hypertension</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000517">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011183">Postoperative Complications</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011446">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013449">Sulfonamides</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000008">administration & dosage</QualifierName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013876">Thiophenes</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000008">administration & dosage</QualifierName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D013999">Timolol</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000008">administration & dosage</QualifierName><QualifierName MajorTopicYN="N" UI="Q000009">adverse effects</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2007</Year><Month>3</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2007</Year><Month>5</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>9</Month><Day>25</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>12</Month><Day>14</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>9</Month><Day>25</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">S0886-3350(07)01185-6</ArticleId><ArticleId IdType="doi">10.1016/j.jcrs.2007.05.039</ArticleId><ArticleId IdType="pubmed">17889772</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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