Neuroplasticity associated with tactile language communication in a deaf-blind subject.
Identifieur interne : 001143 ( PubMed/Corpus ); précédent : 001142; suivant : 001144Neuroplasticity associated with tactile language communication in a deaf-blind subject.
Auteurs : Souzana Obretenova ; Mark A. Halko ; Ela B. Plow ; Alvaro Pascual-Leone ; Lotfi B. MerabetSource :
- Frontiers in human neuroscience [ 1662-5161 ] ; 2010.
Abstract
A long-standing debate in cognitive neuroscience pertains to the innate nature of language development and the underlying factors that determine this faculty. We explored the neural correlates associated with language processing in a unique individual who is early blind, congenitally deaf, and possesses a high level of language function. Using functional magnetic resonance imaging (fMRI), we compared the neural networks associated with the tactile reading of words presented in Braille, Print on Palm (POP), and a haptic form of American Sign Language (haptic ASL or hASL). With all three modes of tactile communication, indentifying words was associated with robust activation within occipital cortical regions as well as posterior superior temporal and inferior frontal language areas (lateralized within the left hemisphere). In a normally sighted and hearing interpreter, identifying words through hASL was associated with left-lateralized activation of inferior frontal language areas however robust occipital cortex activation was not observed. Diffusion tensor imaging -based tractography revealed differences consistent with enhanced occipital-temporal connectivity in the deaf-blind subject. Our results demonstrate that in the case of early onset of both visual and auditory deprivation, tactile-based communication is associated with an extensive cortical network implicating occipital as well as posterior superior temporal and frontal associated language areas. The cortical areas activated in this deaf-blind subject are consistent with characteristic cortical regions previously implicated with language. Finally, the resilience of language function within the context of early and combined visual and auditory deprivation may be related to enhanced connectivity between relevant cortical areas.
DOI: 10.3389/neuro.09.060.2009
PubMed: 20130756
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Plow</name></author><author><name sortKey="Pascual Leone, Alvaro" sort="Pascual Leone, Alvaro" uniqKey="Pascual Leone A" first="Alvaro" last="Pascual-Leone">Alvaro Pascual-Leone</name></author><author><name sortKey="Merabet, Lotfi B" sort="Merabet, Lotfi B" uniqKey="Merabet L" first="Lotfi B" last="Merabet">Lotfi B. Merabet</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.3389/neuro.09.060.2009</idno><idno type="RBID">pubmed:20130756</idno><idno type="pmid">20130756</idno><idno type="wicri:Area/PubMed/Corpus">001143</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Neuroplasticity associated with tactile language communication in a deaf-blind subject.</title><author><name sortKey="Obretenova, Souzana" sort="Obretenova, Souzana" uniqKey="Obretenova S" first="Souzana" last="Obretenova">Souzana Obretenova</name><affiliation><nlm:affiliation>The Berenson-Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School Boston, MA, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Halko, Mark A" sort="Halko, Mark A" uniqKey="Halko M" first="Mark A" last="Halko">Mark A. Halko</name></author><author><name sortKey="Plow, Ela B" sort="Plow, Ela B" uniqKey="Plow E" first="Ela B" last="Plow">Ela B. Plow</name></author><author><name sortKey="Pascual Leone, Alvaro" sort="Pascual Leone, Alvaro" uniqKey="Pascual Leone A" first="Alvaro" last="Pascual-Leone">Alvaro Pascual-Leone</name></author><author><name sortKey="Merabet, Lotfi B" sort="Merabet, Lotfi B" uniqKey="Merabet L" first="Lotfi B" last="Merabet">Lotfi B. Merabet</name></author></analytic><series><title level="j">Frontiers in human neuroscience</title><idno type="eISSN">1662-5161</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A long-standing debate in cognitive neuroscience pertains to the innate nature of language development and the underlying factors that determine this faculty. We explored the neural correlates associated with language processing in a unique individual who is early blind, congenitally deaf, and possesses a high level of language function. Using functional magnetic resonance imaging (fMRI), we compared the neural networks associated with the tactile reading of words presented in Braille, Print on Palm (POP), and a haptic form of American Sign Language (haptic ASL or hASL). With all three modes of tactile communication, indentifying words was associated with robust activation within occipital cortical regions as well as posterior superior temporal and inferior frontal language areas (lateralized within the left hemisphere). In a normally sighted and hearing interpreter, identifying words through hASL was associated with left-lateralized activation of inferior frontal language areas however robust occipital cortex activation was not observed. Diffusion tensor imaging -based tractography revealed differences consistent with enhanced occipital-temporal connectivity in the deaf-blind subject. Our results demonstrate that in the case of early onset of both visual and auditory deprivation, tactile-based communication is associated with an extensive cortical network implicating occipital as well as posterior superior temporal and frontal associated language areas. The cortical areas activated in this deaf-blind subject are consistent with characteristic cortical regions previously implicated with language. Finally, the resilience of language function within the context of early and combined visual and auditory deprivation may be related to enhanced connectivity between relevant cortical areas.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="PubMed-not-MEDLINE"><PMID Version="1">20130756</PMID><DateCreated><Year>2010</Year><Month>02</Month><Day>04</Day></DateCreated><DateCompleted><Year>2011</Year><Month>07</Month><Day>14</Day></DateCompleted><DateRevised><Year>2013</Year><Month>08</Month><Day>13</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1662-5161</ISSN><JournalIssue CitedMedium="Internet"><Volume>3</Volume><PubDate><Year>2010</Year></PubDate></JournalIssue><Title>Frontiers in human neuroscience</Title><ISOAbbreviation>Front Hum Neurosci</ISOAbbreviation></Journal><ArticleTitle>Neuroplasticity associated with tactile language communication in a deaf-blind subject.</ArticleTitle><Pagination><MedlinePgn>60</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3389/neuro.09.060.2009</ELocationID><Abstract><AbstractText>A long-standing debate in cognitive neuroscience pertains to the innate nature of language development and the underlying factors that determine this faculty. We explored the neural correlates associated with language processing in a unique individual who is early blind, congenitally deaf, and possesses a high level of language function. Using functional magnetic resonance imaging (fMRI), we compared the neural networks associated with the tactile reading of words presented in Braille, Print on Palm (POP), and a haptic form of American Sign Language (haptic ASL or hASL). With all three modes of tactile communication, indentifying words was associated with robust activation within occipital cortical regions as well as posterior superior temporal and inferior frontal language areas (lateralized within the left hemisphere). In a normally sighted and hearing interpreter, identifying words through hASL was associated with left-lateralized activation of inferior frontal language areas however robust occipital cortex activation was not observed. Diffusion tensor imaging -based tractography revealed differences consistent with enhanced occipital-temporal connectivity in the deaf-blind subject. Our results demonstrate that in the case of early onset of both visual and auditory deprivation, tactile-based communication is associated with an extensive cortical network implicating occipital as well as posterior superior temporal and frontal associated language areas. The cortical areas activated in this deaf-blind subject are consistent with characteristic cortical regions previously implicated with language. Finally, the resilience of language function within the context of early and combined visual and auditory deprivation may be related to enhanced connectivity between relevant cortical areas.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Obretenova</LastName><ForeName>Souzana</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>The Berenson-Allen Center for Noninvasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School Boston, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Halko</LastName><ForeName>Mark A</ForeName><Initials>MA</Initials></Author><Author ValidYN="Y"><LastName>Plow</LastName><ForeName>Ela B</ForeName><Initials>EB</Initials></Author><Author ValidYN="Y"><LastName>Pascual-Leone</LastName><ForeName>Alvaro</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Merabet</LastName><ForeName>Lotfi B</ForeName><Initials>LB</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2010</Year><Month>01</Month><Day>04</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Front Hum Neurosci</MedlineTA><NlmUniqueID>101477954</NlmUniqueID><ISSNLinking>1662-5161</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Brain Lang. 2002 Aug;82(2):167-78</RefSource><PMID Version="1">12096874</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cogn Neurosci. 2002 Oct 1;14(7):1064-75</RefSource><PMID Version="1">12419129</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain Cogn. 2002 Jun;49(1):170-81</RefSource><PMID Version="1">12027401</PMID></CommentsCorrections><CommentsCorrections 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