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Pathology of 219 human cadaver eyes with 1-piece or 3-piece hydrophobic acrylic intraocular lenses: capsular bag opacification and sites of square-edged barrier breach.

Identifieur interne : 000F08 ( PubMed/Corpus ); précédent : 000F07; suivant : 000F09

Pathology of 219 human cadaver eyes with 1-piece or 3-piece hydrophobic acrylic intraocular lenses: capsular bag opacification and sites of square-edged barrier breach.

Auteurs : Peter J. Ness ; Liliana Werner ; Surekha Maddula ; Don Davis ; Brian Zaugg ; Jack Stringham ; Michael Burrow ; Oliver Yeh

Source :

RBID : pubmed:21419595

English descriptors

Abstract

To assess capsular bag opacification and sites of initial posterior capsule opacification (PCO) in human cadaver eyes with square-edged 1-piece or 3-piece hydrophobic acrylic intraocular lenses (IOLs).

DOI: 10.1016/j.jcrs.2010.11.036
PubMed: 21419595

Links to Exploration step

pubmed:21419595

Le document en format XML

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<title xml:lang="en">Pathology of 219 human cadaver eyes with 1-piece or 3-piece hydrophobic acrylic intraocular lenses: capsular bag opacification and sites of square-edged barrier breach.</title>
<author>
<name sortKey="Ness, Peter J" sort="Ness, Peter J" uniqKey="Ness P" first="Peter J" last="Ness">Peter J. Ness</name>
<affiliation>
<nlm:affiliation>John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
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<author>
<name sortKey="Maddula, Surekha" sort="Maddula, Surekha" uniqKey="Maddula S" first="Surekha" last="Maddula">Surekha Maddula</name>
</author>
<author>
<name sortKey="Davis, Don" sort="Davis, Don" uniqKey="Davis D" first="Don" last="Davis">Don Davis</name>
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<author>
<name sortKey="Zaugg, Brian" sort="Zaugg, Brian" uniqKey="Zaugg B" first="Brian" last="Zaugg">Brian Zaugg</name>
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<author>
<name sortKey="Stringham, Jack" sort="Stringham, Jack" uniqKey="Stringham J" first="Jack" last="Stringham">Jack Stringham</name>
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<author>
<name sortKey="Burrow, Michael" sort="Burrow, Michael" uniqKey="Burrow M" first="Michael" last="Burrow">Michael Burrow</name>
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<author>
<name sortKey="Yeh, Oliver" sort="Yeh, Oliver" uniqKey="Yeh O" first="Oliver" last="Yeh">Oliver Yeh</name>
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<title xml:lang="en">Pathology of 219 human cadaver eyes with 1-piece or 3-piece hydrophobic acrylic intraocular lenses: capsular bag opacification and sites of square-edged barrier breach.</title>
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<name sortKey="Ness, Peter J" sort="Ness, Peter J" uniqKey="Ness P" first="Peter J" last="Ness">Peter J. Ness</name>
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<name sortKey="Davis, Don" sort="Davis, Don" uniqKey="Davis D" first="Don" last="Davis">Don Davis</name>
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<name sortKey="Zaugg, Brian" sort="Zaugg, Brian" uniqKey="Zaugg B" first="Brian" last="Zaugg">Brian Zaugg</name>
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<name sortKey="Stringham, Jack" sort="Stringham, Jack" uniqKey="Stringham J" first="Jack" last="Stringham">Jack Stringham</name>
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<name sortKey="Yeh, Oliver" sort="Yeh, Oliver" uniqKey="Yeh O" first="Oliver" last="Yeh">Oliver Yeh</name>
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<title level="j">Journal of cataract and refractive surgery</title>
<idno type="eISSN">1873-4502</idno>
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<term>Acrylic Resins</term>
<term>Cadaver</term>
<term>Capsule Opacification (etiology)</term>
<term>Capsule Opacification (pathology)</term>
<term>Capsule Opacification (prevention & control)</term>
<term>Humans</term>
<term>Lens Capsule, Crystalline (pathology)</term>
<term>Lens Capsule, Crystalline (ultrasonography)</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Phacoemulsification</term>
<term>Prosthesis Design</term>
<term>Pseudophakia (etiology)</term>
<term>Pseudophakia (pathology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en">
<term>Acrylic Resins</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Capsule Opacification</term>
<term>Pseudophakia</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Capsule Opacification</term>
<term>Lens Capsule, Crystalline</term>
<term>Pseudophakia</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en">
<term>Capsule Opacification</term>
</keywords>
<keywords scheme="MESH" qualifier="ultrasonography" xml:lang="en">
<term>Lens Capsule, Crystalline</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Cadaver</term>
<term>Humans</term>
<term>Lens Implantation, Intraocular</term>
<term>Lenses, Intraocular</term>
<term>Phacoemulsification</term>
<term>Prosthesis Design</term>
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<front>
<div type="abstract" xml:lang="en">To assess capsular bag opacification and sites of initial posterior capsule opacification (PCO) in human cadaver eyes with square-edged 1-piece or 3-piece hydrophobic acrylic intraocular lenses (IOLs).</div>
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<Year>2011</Year>
<Month>04</Month>
<Day>22</Day>
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<Year>2011</Year>
<Month>08</Month>
<Day>12</Day>
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<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1873-4502</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>37</Volume>
<Issue>5</Issue>
<PubDate>
<Year>2011</Year>
<Month>May</Month>
</PubDate>
</JournalIssue>
<Title>Journal of cataract and refractive surgery</Title>
<ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation>
</Journal>
<ArticleTitle>Pathology of 219 human cadaver eyes with 1-piece or 3-piece hydrophobic acrylic intraocular lenses: capsular bag opacification and sites of square-edged barrier breach.</ArticleTitle>
<Pagination>
<MedlinePgn>923-30</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jcrs.2010.11.036</ELocationID>
<Abstract>
<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To assess capsular bag opacification and sites of initial posterior capsule opacification (PCO) in human cadaver eyes with square-edged 1-piece or 3-piece hydrophobic acrylic intraocular lenses (IOLs).</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Experimental study.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Eyes were immersed in 10% formalin after enucleation and had anterior segment scanning with very-high-frequency ultrasound (Artemis). After the eyes were sectioned at the equator, gross examination of the anterior segment was performed from the posterior aspect to assess capsular bag opacification, anterior capsule coverage of the IOL edge, and IOL fixation. Selected eyes had histopathologic examination.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">One hundred nineteen eyes with 1-piece IOLs and 100 with 3-piece IOLs were included in the analyses of capsular bag opacification. There was no difference in central (P=.29) or peripheral (P=.76) PCO. In 63 of 84 eyes with a 1-piece IOL and peripheral PCO, the optic-haptic junction was the site of initiation. In eyes with a 3-piece IOL, initial peripheral PCO was observed at nearly the same rate whether there was full 360-degree anterior capsulorhexis overlap of the optic or no overlap (P=.13). In the latter, the site of PCO initiation was in areas lacking capsulorhexis coverage in 46% of eyes.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">There was no difference in central or peripheral PCO between 1-piece and 3-piece hydrophobic acrylic IOLs. With 1-piece IOLs, PCO tended to start at the optic-haptic junctions. With 3-piece IOLs, full anterior capsule coverage did not produce a statistically significant benefit with respect to PCO prevention.</AbstractText>
<CopyrightInformation>Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
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<LastName>Ness</LastName>
<ForeName>Peter J</ForeName>
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