Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model.
Identifieur interne : 000B43 ( PubMed/Corpus ); précédent : 000B42; suivant : 000B44Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model.
Auteurs : Andrew Ollerton ; Liliana Werner ; Stanley R. Fuller ; Shaheen C. Kavoussi ; J Steele Mcintyre ; Nick MamalisSource :
- Journal of cataract and refractive surgery [ 1873-4502 ] ; 2012.
English descriptors
- KwdEn :
- Acrylic Resins, Animals, Biocompatible Materials, Capsule Opacification (pathology), Capsule Opacification (prevention & control), Hydrophobic and Hydrophilic Interactions, Lens Capsule, Crystalline (pathology), Lens Implantation, Intraocular, Lenses, Intraocular, Materials Testing, Microscopy, Electron, Scanning, Models, Animal, Phacoemulsification, Prosthesis Design, Rabbits, Uveal Diseases (pathology), Uveal Diseases (prevention & control).
- MESH :
- chemical : Acrylic Resins, Biocompatible Materials.
- pathology : Capsule Opacification, Lens Capsule, Crystalline, Uveal Diseases.
- prevention & control : Capsule Opacification, Uveal Diseases.
- Animals, Hydrophobic and Hydrophilic Interactions, Lens Implantation, Intraocular, Lenses, Intraocular, Materials Testing, Microscopy, Electron, Scanning, Models, Animal, Phacoemulsification, Prosthesis Design, Rabbits.
Abstract
To evaluate uveal and capsular biocompatibility of a 1-piece intraocular lens (IOL) manufactured from a new hydrophobic acrylic material that incorporates a barrier step at the optic-haptic junctions.
DOI: 10.1016/j.jcrs.2012.05.039
PubMed: 22920504
Links to Exploration step
pubmed:22920504Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model.</title><author><name sortKey="Ollerton, Andrew" sort="Ollerton, Andrew" uniqKey="Ollerton A" first="Andrew" last="Ollerton">Andrew Ollerton</name><affiliation><nlm:affiliation>Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name></author><author><name sortKey="Fuller, Stanley R" sort="Fuller, Stanley R" uniqKey="Fuller S" first="Stanley R" last="Fuller">Stanley R. Fuller</name></author><author><name sortKey="Kavoussi, Shaheen C" sort="Kavoussi, Shaheen C" uniqKey="Kavoussi S" first="Shaheen C" last="Kavoussi">Shaheen C. Kavoussi</name></author><author><name sortKey="Mcintyre, J Steele" sort="Mcintyre, J Steele" uniqKey="Mcintyre J" first="J Steele" last="Mcintyre">J Steele Mcintyre</name></author><author><name sortKey="Mamalis, Nick" sort="Mamalis, Nick" uniqKey="Mamalis N" first="Nick" last="Mamalis">Nick Mamalis</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="doi">10.1016/j.jcrs.2012.05.039</idno><idno type="RBID">pubmed:22920504</idno><idno type="pmid">22920504</idno><idno type="wicri:Area/PubMed/Corpus">000B43</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model.</title><author><name sortKey="Ollerton, Andrew" sort="Ollerton, Andrew" uniqKey="Ollerton A" first="Andrew" last="Ollerton">Andrew Ollerton</name><affiliation><nlm:affiliation>Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name></author><author><name sortKey="Fuller, Stanley R" sort="Fuller, Stanley R" uniqKey="Fuller S" first="Stanley R" last="Fuller">Stanley R. Fuller</name></author><author><name sortKey="Kavoussi, Shaheen C" sort="Kavoussi, Shaheen C" uniqKey="Kavoussi S" first="Shaheen C" last="Kavoussi">Shaheen C. Kavoussi</name></author><author><name sortKey="Mcintyre, J Steele" sort="Mcintyre, J Steele" uniqKey="Mcintyre J" first="J Steele" last="Mcintyre">J Steele Mcintyre</name></author><author><name sortKey="Mamalis, Nick" sort="Mamalis, Nick" uniqKey="Mamalis N" first="Nick" last="Mamalis">Nick Mamalis</name></author></analytic><series><title level="j">Journal of cataract and refractive surgery</title><idno type="eISSN">1873-4502</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic Resins</term><term>Animals</term><term>Biocompatible Materials</term><term>Capsule Opacification (pathology)</term><term>Capsule Opacification (prevention & control)</term><term>Hydrophobic and Hydrophilic Interactions</term><term>Lens Capsule, Crystalline (pathology)</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Materials Testing</term><term>Microscopy, Electron, Scanning</term><term>Models, Animal</term><term>Phacoemulsification</term><term>Prosthesis Design</term><term>Rabbits</term><term>Uveal Diseases (pathology)</term><term>Uveal Diseases (prevention & control)</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Acrylic Resins</term><term>Biocompatible Materials</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Capsule Opacification</term><term>Lens Capsule, Crystalline</term><term>Uveal Diseases</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Capsule Opacification</term><term>Uveal Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Hydrophobic and Hydrophilic Interactions</term><term>Lens Implantation, Intraocular</term><term>Lenses, Intraocular</term><term>Materials Testing</term><term>Microscopy, Electron, Scanning</term><term>Models, Animal</term><term>Phacoemulsification</term><term>Prosthesis Design</term><term>Rabbits</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To evaluate uveal and capsular biocompatibility of a 1-piece intraocular lens (IOL) manufactured from a new hydrophobic acrylic material that incorporates a barrier step at the optic-haptic junctions.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">22920504</PMID><DateCreated><Year>2012</Year><Month>09</Month><Day>24</Day></DateCreated><DateCompleted><Year>2013</Year><Month>01</Month><Day>09</Day></DateCompleted><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-4502</ISSN><JournalIssue CitedMedium="Internet"><Volume>38</Volume><Issue>10</Issue><PubDate><Year>2012</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Journal of cataract and refractive surgery</Title><ISOAbbreviation>J Cataract Refract Surg</ISOAbbreviation></Journal><ArticleTitle>Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model.</ArticleTitle><Pagination><MedlinePgn>1827-32</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jcrs.2012.05.039</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0886-3350(12)00994-7</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To evaluate uveal and capsular biocompatibility of a 1-piece intraocular lens (IOL) manufactured from a new hydrophobic acrylic material that incorporates a barrier step at the optic-haptic junctions.</AbstractText><AbstractText Label="SETTING" NlmCategory="METHODS">John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</AbstractText><AbstractText Label="DESIGN" NlmCategory="METHODS">Experimental study.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The study IOL (Eternity-Uni W-60) was implanted in the right eyes of 5 New Zealand rabbits and the control IOL (Acrysof SN60WF) in the left eyes. Slitlamp examination was performed 1 through 4 weeks postoperatively. After death, the globes were enucleated and fixed in formalin. Capsular bag opacification scoring (Miyake-Apple view) was then performed followed by complete histopathology.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">At the 4-week examination, the mean posterior capsule opacification (PCO) score was 1.5 ± 1.0 (SD) in the study group and 2.2 ± 1.09 in the control group (P=.02). Anterior capsule opacification (ACO) was not present in the study eyes and was mild in the control eyes. On gross examination, the mean central PCO score was 0.9 ± 0.65 in the study group and 1.7 ± 1.20 in the control group (P=.07); the mean peripheral PCO score was 1.3 ± 0.67 and 2.4 ± 1.14 (P=.01) and the mean Soemmerring ring score was 3.8 ± 0.44 and 4.2 ± 1.09, respectively (P=.47). Histopathology confirmed that both IOLs were equally tolerated by the rabbit eyes.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In this rabbit study, the new hydrophobic acrylic material was biocompatible. The barrier step incorporated to the optic-haptic junctions has the potential to enhance PCO prevention.</AbstractText><CopyrightInformation>Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ollerton</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Werner</LastName><ForeName>Liliana</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Fuller</LastName><ForeName>Stanley R</ForeName><Initials>SR</Initials></Author><Author ValidYN="Y"><LastName>Kavoussi</LastName><ForeName>Shaheen C</ForeName><Initials>SC</Initials></Author><Author ValidYN="Y"><LastName>McIntyre</LastName><ForeName>J Steele</ForeName><Initials>JS</Initials></Author><Author ValidYN="Y"><LastName>Mamalis</LastName><ForeName>Nick</ForeName><Initials>N</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D023362">Evaluation Studies</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>08</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Cataract Refract Surg</MedlineTA><NlmUniqueID>8604171</NlmUniqueID><ISSNLinking>0886-3350</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000180">Acrylic Resins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001672">Biocompatible Materials</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D000180">Acrylic Resins</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D001672">Biocompatible Materials</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D058442">Capsule Opacification</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000517">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D057927">Hydrophobic and Hydrophilic Interactions</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D007903">Lens Capsule, Crystalline</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D019654">Lens Implantation, Intraocular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D007910">Lenses, Intraocular</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008422">Materials Testing</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008855">Microscopy, Electron, Scanning</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D023421">Models, Animal</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018918">Phacoemulsification</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011474">Prosthesis Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011817">Rabbits</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014603">Uveal Diseases</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000473">pathology</QualifierName><QualifierName MajorTopicYN="N" UI="Q000517">prevention & control</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>2</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2012</Year><Month>4</Month><Day>2</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>5</Month><Day>2</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2012</Year><Month>8</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>8</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>8</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>1</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">S0886-3350(12)00994-7</ArticleId><ArticleId IdType="doi">10.1016/j.jcrs.2012.05.039</ArticleId><ArticleId IdType="pubmed">22920504</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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