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Outcomes after lensectomy for children with Marfan syndrome.

Identifieur interne : 000024 ( PubMed/Corpus ); précédent : 000023; suivant : 000025

Outcomes after lensectomy for children with Marfan syndrome.

Auteurs : Sonia Manning ; Bernadette Lanigan ; Michael O'Keefe

Source :

RBID : pubmed:27150966

Abstract

To describe the long-term incidence of retinal detachment, intra- and postoperative complications, and visual and refractive outcomes of children with Marfan syndrome following lensectomy for ectopia lentis, with or without subsequent correction of aphakia using the Artisan aphakic iris-fixated anterior chamber intraocular lens.

DOI: 10.1016/j.jaapos.2016.02.006
PubMed: 27150966

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pubmed:27150966

Le document en format XML

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<name sortKey="Manning, Sonia" sort="Manning, Sonia" uniqKey="Manning S" first="Sonia" last="Manning">Sonia Manning</name>
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<nlm:affiliation>Department of Ophthalmology, Mater Misericordiae University Hospital, Dublin, Ireland.</nlm:affiliation>
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<name sortKey="Lanigan, Bernadette" sort="Lanigan, Bernadette" uniqKey="Lanigan B" first="Bernadette" last="Lanigan">Bernadette Lanigan</name>
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<nlm:affiliation>Department of Ophthalmology, Children's University Hospital Temple Street, Dublin, Ireland.</nlm:affiliation>
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<name sortKey="O Keefe, Michael" sort="O Keefe, Michael" uniqKey="O Keefe M" first="Michael" last="O'Keefe">Michael O'Keefe</name>
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<nlm:affiliation>Department of Ophthalmology, Children's University Hospital Temple Street, Dublin, Ireland. Electronic address: mokeefe@materprivate.ie.</nlm:affiliation>
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<nlm:affiliation>Department of Ophthalmology, Mater Misericordiae University Hospital, Dublin, Ireland.</nlm:affiliation>
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<name sortKey="Lanigan, Bernadette" sort="Lanigan, Bernadette" uniqKey="Lanigan B" first="Bernadette" last="Lanigan">Bernadette Lanigan</name>
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<name sortKey="O Keefe, Michael" sort="O Keefe, Michael" uniqKey="O Keefe M" first="Michael" last="O'Keefe">Michael O'Keefe</name>
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<title level="j">Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus</title>
<idno type="eISSN">1528-3933</idno>
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<div type="abstract" xml:lang="en">To describe the long-term incidence of retinal detachment, intra- and postoperative complications, and visual and refractive outcomes of children with Marfan syndrome following lensectomy for ectopia lentis, with or without subsequent correction of aphakia using the Artisan aphakic iris-fixated anterior chamber intraocular lens.</div>
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<Title>Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus</Title>
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<ArticleTitle>Outcomes after lensectomy for children with Marfan syndrome.</ArticleTitle>
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<AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To describe the long-term incidence of retinal detachment, intra- and postoperative complications, and visual and refractive outcomes of children with Marfan syndrome following lensectomy for ectopia lentis, with or without subsequent correction of aphakia using the Artisan aphakic iris-fixated anterior chamber intraocular lens.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The medical records of children treated at the Department of Ophthalmology, Children's University Hospital, Dublin, Ireland, from January 1, 1991, to December 31, 2011, were retrospectively reviewed. The primary outcome measure was rate of retinal detachment at final follow-up. Secondary outcomes included postoperative complications, endothelial cell count, visual acuity, refractive error, and postoperative refraction prediction error.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 30 eyes of 15 patients underwent lensectomy. Of these, 16 eyes of 8 patients subsequently underwent Artisan implantation. Mean follow-up was 13.8 ± 5.9 years after lensectomy and 4.1 ± 2.8 years after Artisan implantation. There were no cases of retinal detachment. Best-corrected visual acuity was 0.11 ± 0.14 (logMAR) post-lensectomy and 0.12 ± 0.19 post-Artisan implantation. Endothelial cell count of the pseudophakic group was 3109 ± 458 preoperatively and 2632 ± 592 postoperatively. Mean cell loss was 15.4%. One eye required repeat surgical peripheral iridectomy for pseudophakic pupillary block. One eye required re-enclavation of a dislocated Artisan IOL haptic; the same eye required anterior vitrectomy for removal of retained lens fragment from the original lensectomy.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In this study cohort, there was no increased incidence of retinal detachment in children with Marfan syndrome and ectopia lentis in the setting of one or more prior intraocular procedures. A moderate rate of endothelial cell loss was observed.</AbstractText>
<CopyrightInformation>Copyright © 2016 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.</CopyrightInformation>
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<Affiliation>Department of Ophthalmology, Mater Misericordiae University Hospital, Dublin, Ireland.</Affiliation>
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<Affiliation>Department of Ophthalmology, Children's University Hospital Temple Street, Dublin, Ireland.</Affiliation>
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<Affiliation>Department of Ophthalmology, Children's University Hospital Temple Street, Dublin, Ireland. Electronic address: mokeefe@materprivate.ie.</Affiliation>
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