Neural activities of tactile crossmodal working memory in humans: an event-related potential study
Identifieur interne : 001925 ( Pmc/Curation ); précédent : 001924; suivant : 001926Neural activities of tactile crossmodal working memory in humans: an event-related potential study
Auteurs : Shinji Ohara [États-Unis] ; Liping Wang [États-Unis, République populaire de Chine] ; Yixuan Ku [États-Unis, République populaire de Chine] ; Fred A. Lenz [États-Unis] ; Steven S. Hsiao [États-Unis] ; Bo Hong [États-Unis, République populaire de Chine] ; Yong-Di Zhou [États-Unis]Source :
- Neuroscience [ 0306-4522 ] ; 2008.
Abstract
In the present study, we examined the neural mechanisms underlying crossmodal working memory by analyzing scalp-recorded event-related potentials (ERPs) from normal human subjects performing tactile-tactile unimodal or tactile-auditory crossmodal delay tasks that consisted of stimulus-1 (S-1, tactile), interval (delay), and stimulus-2 (S-2, tactile or auditory). We hypothesized that there are sequentially discrete task-correlated changes in ERPs representing neural processes of tactile working memory, and in addition, significant differences would be observed in ERPs between the unimodal task and the crossmodal task.
In comparison to the ERP components in the unimodal task, two late positive ERP components (LPC-1 and LPC-2) evoked by the tactile S-1 in the delay of the crossmodal task were enhanced by expectation of the associated auditory S-2 presented at the end of the delay. Such enhancement might represent neural activities involved in crossmodal association between the tactile stimulus and the auditory stimulus. Later in the delay, a late negative component (LNC) was observed. The amplitude of LNC depended on information retained during the delay, and when the same information was retained, this amplitude was not influenced by modality or location of S-2 (auditory S-2 through headphones, or tactile S-2 on the left index finger). LNC might represent the neural activity involved in working memory. The above results suggest that the sequential ERP changes in the present study represent temporally distinguishable neural processes, such as the crossmodal association and crossmodal working memory.
Url:
DOI: 10.1016/j.neuroscience.2007.12.043
PubMed: 18304742
PubMed Central: 3343365
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001925
Links to Exploration step
PMC:3343365Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neural activities of tactile crossmodal working memory in humans: an event-related potential study</title>
<author><name sortKey="Ohara, Shinji" sort="Ohara, Shinji" uniqKey="Ohara S" first="Shinji" last="Ohara">Shinji Ohara</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Liping" sort="Wang, Liping" uniqKey="Wang L" first="Liping" last="Wang">Liping Wang</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A5">The Institute of Cognitive Neuroscience, East China Normal University, Shanghai, P. R. China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Institute of Cognitive Neuroscience, East China Normal University, Shanghai</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ku, Yixuan" sort="Ku, Yixuan" uniqKey="Ku Y" first="Yixuan" last="Ku">Yixuan Ku</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">Tsinghua University, Beijing, P. R. China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Tsinghua University, Beijing</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lenz, Fred A" sort="Lenz, Fred A" uniqKey="Lenz F" first="Fred A." last="Lenz">Fred A. Lenz</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hsiao, Steven S" sort="Hsiao, Steven S" uniqKey="Hsiao S" first="Steven S." last="Hsiao">Steven S. Hsiao</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A3">Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neuroscience, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hong, Bo" sort="Hong, Bo" uniqKey="Hong B" first="Bo" last="Hong">Bo Hong</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">Tsinghua University, Beijing, P. R. China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Tsinghua University, Beijing</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhou, Yong Di" sort="Zhou, Yong Di" uniqKey="Zhou Y" first="Yong-Di" last="Zhou">Yong-Di Zhou</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">18304742</idno>
<idno type="pmc">3343365</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343365</idno>
<idno type="RBID">PMC:3343365</idno>
<idno type="doi">10.1016/j.neuroscience.2007.12.043</idno>
<date when="2008">2008</date>
<idno type="wicri:Area/Pmc/Corpus">001925</idno>
<idno type="wicri:Area/Pmc/Curation">001925</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Neural activities of tactile crossmodal working memory in humans: an event-related potential study</title>
<author><name sortKey="Ohara, Shinji" sort="Ohara, Shinji" uniqKey="Ohara S" first="Shinji" last="Ohara">Shinji Ohara</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Liping" sort="Wang, Liping" uniqKey="Wang L" first="Liping" last="Wang">Liping Wang</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A5">The Institute of Cognitive Neuroscience, East China Normal University, Shanghai, P. R. China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Institute of Cognitive Neuroscience, East China Normal University, Shanghai</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Ku, Yixuan" sort="Ku, Yixuan" uniqKey="Ku Y" first="Yixuan" last="Ku">Yixuan Ku</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">Tsinghua University, Beijing, P. R. China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Tsinghua University, Beijing</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Lenz, Fred A" sort="Lenz, Fred A" uniqKey="Lenz F" first="Fred A." last="Lenz">Fred A. Lenz</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hsiao, Steven S" sort="Hsiao, Steven S" uniqKey="Hsiao S" first="Steven S." last="Hsiao">Steven S. Hsiao</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A3">Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neuroscience, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hong, Bo" sort="Hong, Bo" uniqKey="Hong B" first="Bo" last="Hong">Bo Hong</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">Tsinghua University, Beijing, P. R. China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Tsinghua University, Beijing</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Zhou, Yong Di" sort="Zhou, Yong Di" uniqKey="Zhou Y" first="Yong-Di" last="Zhou">Yong-Di Zhou</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurosurgery, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A2">Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Neuroscience</title>
<idno type="ISSN">0306-4522</idno>
<idno type="eISSN">1873-7544</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P2">In the present study, we examined the neural mechanisms underlying crossmodal working memory by analyzing scalp-recorded event-related potentials (ERPs) from normal human subjects performing tactile-tactile unimodal or tactile-auditory crossmodal delay tasks that consisted of stimulus-1 (S-1, tactile), interval (delay), and stimulus-2 (S-2, tactile or auditory). We hypothesized that there are sequentially discrete task-correlated changes in ERPs representing neural processes of tactile working memory, and in addition, significant differences would be observed in ERPs between the unimodal task and the crossmodal task.</p>
<p id="P3">In comparison to the ERP components in the unimodal task, two late positive ERP components (LPC-1 and LPC-2) evoked by the tactile S-1 in the delay of the crossmodal task were enhanced by expectation of the associated auditory S-2 presented at the end of the delay. Such enhancement might represent neural activities involved in crossmodal association between the tactile stimulus and the auditory stimulus. Later in the delay, a late negative component (LNC) was observed. The amplitude of LNC depended on information retained during the delay, and when the same information was retained, this amplitude was not influenced by modality or location of S-2 (auditory S-2 through headphones, or tactile S-2 on the left index finger). LNC might represent the neural activity involved in working memory. The above results suggest that the sequential ERP changes in the present study represent temporally distinguishable neural processes, such as the crossmodal association and crossmodal working memory.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">7605074</journal-id>
<journal-id journal-id-type="pubmed-jr-id">6087</journal-id>
<journal-id journal-id-type="nlm-ta">Neuroscience</journal-id>
<journal-id journal-id-type="iso-abbrev">Neuroscience</journal-id>
<journal-title-group><journal-title>Neuroscience</journal-title>
</journal-title-group>
<issn pub-type="ppub">0306-4522</issn>
<issn pub-type="epub">1873-7544</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">18304742</article-id>
<article-id pub-id-type="pmc">3343365</article-id>
<article-id pub-id-type="doi">10.1016/j.neuroscience.2007.12.043</article-id>
<article-id pub-id-type="manuscript">NIHMS46180</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Neural activities of tactile crossmodal working memory in humans: an event-related potential study</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Ohara</surname>
<given-names>Shinji</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Wang</surname>
<given-names>Liping</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ku</surname>
<given-names>Yixuan</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Lenz</surname>
<given-names>Fred A.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hsiao</surname>
<given-names>Steven S.</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hong</surname>
<given-names>Bo</given-names>
</name>
<xref ref-type="aff" rid="A4">4</xref>
<xref ref-type="aff" rid="A6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zhou</surname>
<given-names>Yong-Di</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Department of Neurosurgery, Johns Hopkins University, Baltimore, MD, USA</aff>
<aff id="A2"><label>2</label>
Krieger Mind / Brain Institute, Johns Hopkins University, Baltimore, MD, USA</aff>
<aff id="A3"><label>3</label>
Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USA</aff>
<aff id="A4"><label>4</label>
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA</aff>
<aff id="A5"><label>5</label>
The Institute of Cognitive Neuroscience, East China Normal University, Shanghai, P. R. China</aff>
<aff id="A6"><label>6</label>
Tsinghua University, Beijing, P. R. China</aff>
<author-notes><corresp id="FN1">Correspondence: Yong-Di Zhou, Ph.D., Meyer 8-181D, Department of Neurosurgery, School of Medicine, Johns Hopkins University, 600 N. Wolfe Street, Baltimore, MD 21287, Tel: 410-955-5774, Fax: 443-287-8044, <email>yzhou12@jhmi.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>20</day>
<month>4</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="epub"><day>12</day>
<month>1</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="ppub"><day>27</day>
<month>3</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>04</day>
<month>5</month>
<year>2012</year>
</pub-date>
<volume>152</volume>
<issue>3</issue>
<fpage>692</fpage>
<lpage>702</lpage>
<permissions><copyright-statement>© 2007 IBRO. Published by Elsevier Ltd. All rights reserved.</copyright-statement>
<copyright-year>2007</copyright-year>
</permissions>
<abstract><p id="P2">In the present study, we examined the neural mechanisms underlying crossmodal working memory by analyzing scalp-recorded event-related potentials (ERPs) from normal human subjects performing tactile-tactile unimodal or tactile-auditory crossmodal delay tasks that consisted of stimulus-1 (S-1, tactile), interval (delay), and stimulus-2 (S-2, tactile or auditory). We hypothesized that there are sequentially discrete task-correlated changes in ERPs representing neural processes of tactile working memory, and in addition, significant differences would be observed in ERPs between the unimodal task and the crossmodal task.</p>
<p id="P3">In comparison to the ERP components in the unimodal task, two late positive ERP components (LPC-1 and LPC-2) evoked by the tactile S-1 in the delay of the crossmodal task were enhanced by expectation of the associated auditory S-2 presented at the end of the delay. Such enhancement might represent neural activities involved in crossmodal association between the tactile stimulus and the auditory stimulus. Later in the delay, a late negative component (LNC) was observed. The amplitude of LNC depended on information retained during the delay, and when the same information was retained, this amplitude was not influenced by modality or location of S-2 (auditory S-2 through headphones, or tactile S-2 on the left index finger). LNC might represent the neural activity involved in working memory. The above results suggest that the sequential ERP changes in the present study represent temporally distinguishable neural processes, such as the crossmodal association and crossmodal working memory.</p>
</abstract>
<kwd-group><kwd>auditory</kwd>
<kwd>ERP</kwd>
<kwd>crossmodal</kwd>
<kwd>human</kwd>
<kwd>working memory</kwd>
</kwd-group>
<funding-group><award-group><funding-source country="United States">National Institute of Neurological Disorders and Stroke : NINDS</funding-source>
<award-id>R01 NS040059-04 || NS</award-id>
</award-group>
<award-group><funding-source country="United States">National Institute of Neurological Disorders and Stroke : NINDS</funding-source>
<award-id>R01 NS038493-08 || NS</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001925 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 001925 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Pmc |étape= Curation |type= RBID |clé= PMC:3343365 |texte= Neural activities of tactile crossmodal working memory in humans: an event-related potential study }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:18304742" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \ | NlmPubMed2Wicri -a HapticV1
This area was generated with Dilib version V0.6.23. |