Current progress in patient-specific modeling
Identifieur interne : 001323 ( Pmc/Curation ); précédent : 001322; suivant : 001324Current progress in patient-specific modeling
Auteurs : Maxwell Lewis Neal ; Roy KerckhoffsSource :
- Briefings in Bioinformatics [ 1467-5463 ] ; 2009.
Abstract
We present a survey of recent advancements in the emerging field of patient-specific modeling (PSM). Researchers in this field are currently simulating a wide variety of tissue and organ dynamics to address challenges in various clinical domains. The majority of this research employs three-dimensional, image-based modeling techniques. Recent PSM publications mostly represent feasibility or preliminary validation studies on modeling technologies, and these systems will require further clinical validation and usability testing before they can become a standard of care. We anticipate that with further testing and research, PSM-derived technologies will eventually become valuable, versatile clinical tools.
Url:
DOI: 10.1093/bib/bbp049
PubMed: 19955236
PubMed Central: 2810113
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<front><div type="abstract" xml:lang="en"><p>We present a survey of recent advancements in the emerging field of patient-specific modeling (PSM). Researchers in this field are currently simulating a wide variety of tissue and organ dynamics to address challenges in various clinical domains. The majority of this research employs three-dimensional, image-based modeling techniques. Recent PSM publications mostly represent feasibility or preliminary validation studies on modeling technologies, and these systems will require further clinical validation and usability testing before they can become a standard of care. We anticipate that with further testing and research, PSM-derived technologies will eventually become valuable, versatile clinical tools.</p>
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<bio><p><bold>Maxwell Lewis Neal</bold>
earned his BS in Biology from Case Western Reserve University in 1999. He has experience modeling brain, bones and the cardiovascular system. He is presently a PhD candidate in the Division of Biomedical and Health Informatics at the University of Washington, and his current research focuses on creating informatics tools to support biosimulation modeling.</p>
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<bio><p><bold>Roy Kerckhoffs</bold>
earned his PhD degree in biomedical engineering in 2003 at Eindhoven University of Technology in the Netherlands. He is working as a Project Scientist at the Cardiac Mechanics Research Group at the University of California San Diego. His research interests include multiscale modeling of cardiovascular mechanics and electrophysiology. Currently, his main focus lies on the development of multiscale (animal- and patient-specific) computational models of cardiac electromechanics.</p>
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<author-notes><corresp>Corresponding author. Roy Kerckhoffs, Department of Bioengineering, Mailcode #0412, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0412, USA. Tel: <phone>+1-858-822-4872</phone>
; Fax: <fax>+1-858-534-5722</fax>
; E-mail: <email>roy@bioeng.ucsd.edu</email>
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<permissions><copyright-statement>© The Author 2009. Published by Oxford University Press. For Permissions, please email: journals.permissions@oxfordjournals.org</copyright-statement>
<copyright-year>2009</copyright-year>
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<abstract><p>We present a survey of recent advancements in the emerging field of patient-specific modeling (PSM). Researchers in this field are currently simulating a wide variety of tissue and organ dynamics to address challenges in various clinical domains. The majority of this research employs three-dimensional, image-based modeling techniques. Recent PSM publications mostly represent feasibility or preliminary validation studies on modeling technologies, and these systems will require further clinical validation and usability testing before they can become a standard of care. We anticipate that with further testing and research, PSM-derived technologies will eventually become valuable, versatile clinical tools.</p>
</abstract>
<kwd-group><kwd>computer simulation</kwd>
<kwd>clinical decision support techniques</kwd>
<kwd>computer-assisted three dimensional imaging</kwd>
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